Oral Health Probiotics WiseBiotics Mint Ingredients & Drug Interactions
by NatureWise
What is this page for?
First and foremost: checking Oral Health Probiotics WiseBiotics Mint against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Oral Health Probiotics WiseBiotics Mint is a dietary supplement by NatureWise with 12 active ingredients. Its ingredients are commonly taken for digestive health and regularity, infant colic and gut support, diarrhea (including antibiotic-related).Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are B. breve. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Oral Health Probiotics WiseBiotics Mint by NatureWise
Ask about any prescription or over-the-counter medication and we check it for interactions with Oral Health Probiotics WiseBiotics Mint by NatureWise — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Oral Health Probiotics WiseBiotics Mint by NatureWise
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This tablet contains 12 active probiotic ingredients—mostly beneficial bacteria strains meant to support oral health. The two we could verify are Bifidobacterium breve and Streptococcus thermophilus; the others (including several Lactobacillus and Bifidobacterium species, plus two Streptococcus salivarius strains) are part of what's called an Oral Health Probiotic Blend.
The inactive ingredients are standard tablet binders and fillers like inulin, dicalcium phosphate, and stevia leaf extract for sweetness—plus natural peppermint flavor.
Does it work?
Not established
The evidence for what these probiotics actually do is limited. For Bifidobacterium breve, studies suggest it's possibly ineffective for age-related cognitive decline and sepsis, but there isn't enough reliable data to rate it for antibiotic-associated diarrhea, hay fever, or other allergic conditions.
Streptococcus thermophilus shows insufficient evidence for antibiotic-associated diarrhea, bacterial vaginosis, constipation, diabetes, and other conditions listed. We don't have effectiveness ratings on file for the other strains in the blend.
How safe is it?
Well-documented data
Both B. breve and S. thermophilus are generally well tolerated in healthy people, but probiotics do come with caveats. Caution is needed if you're very ill, immunocompromised, or a preterm infant—there are rare but documented cases of these bacteria causing bloodstream infections in critically ill patients and newborns.
Bloating and flatulence have been reported with probiotic use generally. The safety data on probiotic supplements is limited, so check with your doctor before you start, especially if you have a weakened immune system or are facing critical illness.
Meds to double-check
Moderate interaction found
Antibiotic drugs are the main concern—they can reduce how well this probiotic works by killing the live bacteria in it. Separate your doses and talk to your pharmacist about timing.
We couldn't verify interactions for most of the other probiotic strains in the blend, so run your medications through the checker on this page to be sure.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
This is a probiotic blend aimed at oral health, but the evidence for its effectiveness isn't strong yet. The main thing to watch is if you're taking antibiotics—they'll interfere with the live bacteria in this supplement.
If you're healthy and not on antibiotics, it's generally well tolerated, but it's worth a quick conversation with your pharmacist or doctor first, especially if you have any immune system concerns.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 12 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Oral Health Probiotics WiseBiotics Mint, straight from the product label.
| Brand | NatureWise |
|---|---|
| Barcode (UPC) | 858081006356 |
| Net contents | 50 Chewable Mint Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Mar 25, 2025 |
| DSLD ID | 327773 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Children 4 or More Years of Age, Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Oral Health Probiotics WiseBiotics Mint by NatureWise, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L. plantarum | 0 NP | -- |
| B. breve | 0 NP | -- |
| L. paracasei LPC-37 | 0 NP | -- |
| L. reuteri | 0 NP | -- |
| L. salivarius | 0 NP | -- |
| S. thermophilus | 0 NP | -- |
| L. casei | 0 NP | -- |
| B. longum infantis | 0 NP | -- |
| L. rhamnosus GG | 0 NP | -- |
| B. animalis lactis BL-04 | 0 NP | -- |
| Oral Health Probiotic Blend | 110 mg | -- |
| S. salivarius BLIS M18 | 0 NP | -- |
| S. salivarius BLIS-K12 | 0 NP | -- |
Other ingredients: Isomalt, Inulin, Behenoyl Polyoxyl-8 Glycerides, Dicalcium Phosphate, Peppermint Flavor, Natural, Stevia leaf extract
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Gluten free
Advanced oral care
Advanced protection for teeth & gums + better breath & upper resiratory immune support for healthy ears nose & throat
This product does not contain: Wheat, gluten, soy, eggs, tree nuts, peanuts, fish, or shellfish.
Suggested/Recommended/Usage/Directions
Suggested use: After brushing teeth or using mouthwash, chew or suck 1 tablet once or twice daily, or as recommended by your healthcare provider. NatureWise Oral Health Probiotics should always be taken in conjunction with a healthy diet.
Precautions
Caution: As with any dietary supplement, you should consult your healthcare provider before use, especially if pregnant, nursing, have a medical condition, taking medications, or have known adverse reactions or allergies.
Caution: As with any dietary supplement, you should consult your healthcare provider before use, especially if pregnant, nursing, have a medical condition, taking medications, or have known adverse reactions or allergies.
Contains trace amounts of milk protein from the fermentation process.
Keep out of the reach of children, except under adult supervision.
Do not use if safety seal is damaged or missing.
Formula
NatureWise Oral Health Probiotics is intelligently formulated with 12 strains of probiotics, including BLIS K12 & BLIS M18, that have been researched for their potential benefits for dental and upper respiratory system, which may contribute to the overall health of the ear, nose, and throat wellness.
For children & adults
General Statements
To learn more about NatureWise Oral Health Probiotics and our other great products, please visit us at naturewise.com.
Brand IP Statement(s)
Copyright 2023 NatureWise. All rights reserved.
BLIS and BLIS K12 are trademarks of Blis Technologies Limited and the subject of USA patent no. 6772912. BLIS and BLIS M18 are trademarks of Blis Technologies Limited and the subject of USA patent no. 7226590.
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Storage
Store in a cool, dry place.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Oral Health Probiotics WiseBiotics Mint by NatureWise label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Oral Health Probiotics WiseBiotics Mint by NatureWise
These are the 12 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Chewable Tablet(s) Dosage formTablet Or Pill Servings per container50 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Oral Health Probiotic Blend
- › L. plantarum
- › B. breve
- › L. paracasei LPC-37
- › L. reuteri
- › L. salivarius
- › S. thermophilus
- › L. casei
- › B. longum infantis
- › L. rhamnosus GG
- › B. animalis lactis BL-04
- › S. salivarius BLIS M18
- › S. salivarius BLIS-K12
Other (inactive) ingredients: Isomalt, Inulin, Behenoyl Polyoxyl-8 Glycerides, Dicalcium Phosphate, Peppermint Flavor, Natural, Stevia leaf extract. These complete the product’s ingredient list but are not active constituents.
Oral Health Probiotics WiseBiotics Mint by NatureWise Drug Interactions
HelloPharmacist Interaction Report
NatureWise Oral Health Probiotics WiseBiotics Mint contains live probiotic bacteria, and one of them—Bifidobacterium breve—does interact with medications.
The main concern is antibiotic drugs: since antibiotics kill bacteria, they can wipe out a significant portion of the B. breve organisms in the supplement, making the probiotic less effective. If you're on an antibiotic, separate your doses—take one in the morning and the other several hours later, and talk to your pharmacist about timing.
Read the full breakdown — every affected drug type, severity by severity
We couldn't check the interaction data for several of the other probiotic strains in this product: L. plantarum, L. paracasei, L. reuteri, L. salivarius, L. casei, B. longum infantis, L. rhamnosus GG, B. animalis lactis, S. salivarius BLIS M18, and S. salivarius BLIS-K12. One ingredient, S. thermophilus, was checked and has no documented interactions.
Altogetherr, these interactions span 182 individual medications. Use the medication checker below to see if any of your prescriptions appear, and talk to your pharmacist before you start—especially if you're on antibiotics.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Oral Health Probiotics WiseBiotics Mint?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Oral Health Probiotics WiseBiotics Mint interact with 182 drugs. Click any drug to see the details.
1 of the 12 ingredients in Oral Health Probiotics WiseBiotics Mint interact with drugs. Each result below shows which ingredient is responsible. B. breve
AmikacinAmikin, Arikayce
How Amikacin interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Amikacin interactionAmoxicillinAmix, Amoram, Amoxident, Amoxil Capsules, Amoxil Injection, Galenamox +3 more
How Amoxicillin interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Amoxicillin interactionAmoxicillin VeterinaryBiomox
How Amoxicillin Veterinary interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Amoxicillin Veterinary interactionAmoxicillin, Clavulanate PotassiumAugmentin, Augmentin '125/31 SF', Augmentin '250/62 SF', Augmentin XR, Augmentin-Duo 400/57, Clavulin
How Amoxicillin, Clavulanate Potassium interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Amoxicillin, Clavulanate Potassium interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Amphotericin, Tetracycline interactionAmpicillinOmnipen, Omnipen-N, Penbritin, Principen, Rimacillin
How Ampicillin interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Ampicillin interactionAmpicillin, SulbactamUnasyn
How Ampicillin, Sulbactam interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Ampicillin, Sulbactam interactionAvibactam Sodium, CeftazidimeAvycaz
How Avibactam Sodium, Ceftazidime interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Avibactam Sodium, Ceftazidime interactionAzithromycinAzasite, Zithromax, Zmax
How Azithromycin interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Azithromycin interactionAztreonamAzactam
How Aztreonam interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Aztreonam interactionBacampicillinPenglobe
How Bacampicillin interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Bacampicillin interactionBacitracinBaci-IM, Baciguent, Bacitracin Ointment
How Bacitracin interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Bacitracin interactionBenznidazoleBenznidazole
How Benznidazole interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Benznidazole interactionBismuth Subsalicylate, Metronidazole, TetracyclineHelidac
How Bismuth Subsalicylate, Metronidazole, Tetracycline interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionCapreomycinCapastat
How Capreomycin interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Capreomycin interactionCarbenicillin Indanyl SodiumGeocillin
How Carbenicillin Indanyl Sodium interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Carbenicillin Indanyl Sodium interactionCefaclorCeclor, Ceclor CD
How Cefaclor interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Cefaclor interactionCefadroxilCef-Tab, Duricef, Ultracef
How Cefadroxil interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Cefadroxil interactionCefamandoleMandol
How Cefamandole interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Cefamandole interactionCefazolinAncef
How Cefazolin interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Cefazolin interactionCefdinirOmnicef
How Cefdinir interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Cefdinir interactionCefditoren PivoxilSpectracef
How Cefditoren Pivoxil interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Cefditoren Pivoxil interactionCefepimeMaxipime
How Cefepime interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Cefepime interactionCefiderocol Sulfate TosylateFetroja
How Cefiderocol Sulfate Tosylate interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Cefiderocol Sulfate Tosylate interactionCefiximeSuprax
How Cefixime interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Cefixime interactionCefmetazoleZefazone
How Cefmetazole interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Cefmetazole interactionCefonicidMonocid
How Cefonicid interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Cefonicid interactionCefoperazoneCefobid
How Cefoperazone interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Cefoperazone interactionCefotaximeClaforan
How Cefotaxime interacts with Oral Health Probiotics WiseBiotics Mint — through 1 ingredient. Tap an ingredient for the detail:
B. BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve + Cefotaxime interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Oral Health Probiotics WiseBiotics Mint with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
B. breve
Antibiotic Drugs
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B. breve.
Since B. breve preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. breve preparations by at least 2 hours.
Brand information
Manufacturer and brand details for Oral Health Probiotics WiseBiotics Mint, from the product label.
NatureWise
See all NatureWise products- Name
- NatureWise
- City
- Costa Mesa
- State
- CA
- ZipCode
- 92626
- Phone Number
- 800-510-7207
- Web Address
- naturewise.com
Oral Health Probiotics WiseBiotics Mint by NatureWise: Common Questions
Does Oral Health Probiotics WiseBiotics Mint by NatureWise interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this probiotic work if I'm on an antibiotic?
Is it safe for me if I have a weak immune system?
Can I take this while pregnant or breastfeeding?
What does 'oral health' mean for these probiotics?
Will this cause bloating or gas?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Oral Health Probiotics WiseBiotics Mint is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Oral Health Probiotics WiseBiotics Mint’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Bifidobacterium Breve
Interacts with 182 drugsBifidobacterium breve is a 'friendly' gut bacterium taken as a probiotic, most often to support digestion and balance the gut microbiome. Some studies suggest possible benefits for certain d...
Read the full Bifidobacterium Breve monograph → Herb & supplement monographStreptococcus Thermophilus
Streptococcus thermophilus is a friendly bacterium used as a probiotic, often combined with other strains in yogurt and supplements. It is generally well tolerated in healthy people and may...
Read the full Streptococcus Thermophilus monograph →Sources & How We Checked
Oral Health Probiotics WiseBiotics Mint's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 30 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Bifidobacterium Breve 9 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Ohishi A, Takahashi S, Ito Y, et al. Bifidobacterium septicemia associated with postoperative probiotic therapy in a neonate with omphalocele. J Pediatr. 2010;156(4):679-81. PubMed
- Sakurai Y, Watanabe T, Miura Y, et al. Clinical and bacteriologic characteristics of six cases of Bifidobacterium breve bacteremia due to probiotic administration in the neonatal intensive care unit. Pediatr Infect Dis J 2022;41(1):62-65. PubMed
- Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
- Wakabayashi Y, Nakayama S, Yamamoto A, et al. First case of necrotizing fasciitis and bacteremia caused by Bifidobacteriumbreve. Anaerobe 2022;76:102613.
- Takeda Y, Ota K, Kondo A, et al. A case of necrotizing fasciitis caused by Bifidobacterium breve. IDCases 2022;31:e01667. PubMed
- Suwantarat N, Romagnoli M, Wakefield T, Carroll KC. Ventriculoperitoneal shunt infection caused by Bifidobacterium breve. Anaerobe 2014;28:1-3. PubMed
See these in context on the Bifidobacterium Breve monograph →
Streptococcus Thermophilus 21 references
- Saxelin M, Chuang NH, Chassy B, et al. Lactobacilli and bacteremia in southern Finland 1989-1992. Clin Infect Dis 1996;22:564-6. PubMed
- Tynkkynen S, Singh KV, Varmanen P. Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes. Int J Food Microbiol 1998;41:195-204. PubMed
- Klein G, Zill E, Schindler R, et al. Peritonitis associated with vancomycin-resistant Lactobacillus rhamnosus in a continuous ambulatory peritoneal dialysis patient; organism identification, antibiotic therapy, and case report. J Clin Microbiol 1998;36:
- Kalima P, Masterton RG, Roddie PH, et al. Lactobacillus rhamnosus infection in a child following bone marrow transplant. J Infect 1996;32:165-7. PubMed
- Goldin BR. Health Benefits of probiotics. Br J Nutr 1998;80:S203-7. DOI
- Rautio M, Jousimies-Somer H, Kauma H, et al. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. Clin Infect Dis 1999;28:1159-60.
- MacGregor G, Smith AJ, Thakker B, Kinsella J. Yoghurt biotherapy: contraindicated in immunosuppressed patients? Postgrad Med J 2002;78:366-7. PubMed
- Land MH, Rouster-Stevens K, Woods CR, et al. Lactobacillus sepsis associated with probiotic therapy. Pediatrics 2005;115:178-81.
- De Groote MA, Frank DN, Dowell E, et al. Lactobacillus rhamnosus GG bacteremia associated with probiotic use in a child with short gut syndrome. Pediatr Infect Dis J 2005;24:278-80. PubMed
- Vahabnezhad E, Mochon AB, Wozniak LJ, Ziring DA. Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis. J Clin Gastroenterol. 2013;47(5):437-9. PubMed
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See these in context on the Streptococcus Thermophilus monograph →
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