Interactions on record — worth a quick check against your medications. Based on 2 of 5 ingredients. Check your meds →
Dietary supplement

Oral & Sinus Cinnamon Stick Flavor Ingredients & Drug Interactions

by SimplyBiotix

Oral & Sinus Cinnamon Stick Flavor label
See full label image
Lozenge Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Oral & Sinus Cinnamon Stick Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Oral & Sinus Cinnamon Stick Flavor is a dietary supplement by SimplyBiotix with 5 active ingredients. Its ingredients are commonly taken for zinc deficiency, immune support, cold symptoms.Based on those ingredients, 764 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin D, Zinc. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Oral & Sinus Cinnamon Stick Flavor by SimplyBiotix

Ask about any prescription or over-the-counter medication and we check it for interactions with Oral & Sinus Cinnamon Stick Flavor by SimplyBiotix — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Oral & Sinus Cinnamon Stick Flavor by SimplyBiotix

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 2 of its 5 active ingredients.
  • “Oral & Sinus Probiotic Blend” is a proprietary blend — the label gives one combined amount (40 mg) without saying how much of each component you get.

This lozenge has 5 ingredients, including two active ones: zinc and vitamin D. Zinc plays a role in immune function and wound healing; vitamin D is essential for bone health and calcium absorption.

The product also contains three probiotic strains — L. reuteri, S. salivarius K12, and S. salivarius M18 — though we hold no interaction data for those. The rest is inactive ingredients: isomalt (a sugar substitute), microcrystalline cellulose and stearic acid (binders), dicalcium phosphate, and natural cinnamon and vanilla flavors with stevia for sweetness.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: ear, nose, throat, oral, and immune health.
  • We looked for evidence on: Allergic rhinitis (hay fever), Asthma, Canker sores, Coronavirus disease 2019 (COVID-19), Dental caries, Gingivitis — and 4 related terms.
  • The strongest evidence on file: Vitamin D is rated "Possibly Effective" for Dental caries (Natural Medicines).
  • Also on file: Vitamin D is rated "Possibly Effective" for Coronavirus disease 2019 (COVID-19), Allergic rhinitis (hay fever).
  • Also on file: Zinc is rated "Possibly Effective" for Gingivitis, Herpes labialis (cold sores), Halitosis, Coronavirus disease 2019 (COVID-19).

Zinc is effective for zinc deficiency and likely effective for Wilson disease (a copper storage disorder). For acne, age-related eye disease, diabetes, and a rare skin condition called acrodermatitis enteropathica, the evidence is possible but not yet strong enough to call it proven.

Vitamin D is effective for rickets, renal bone disease, familial hypophosphatemia, osteomalacia (soft bones), and hypoparathyroidism. The evidence we hold doesn't address whether this lozenge works for oral or sinus health specifically.

The evidence, ingredient by ingredient Zinc Vitamin D

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Zinc is well tolerated in doses below 40 mg daily (the safe upper limit for adults). At recommended amounts, the most common side effects are abdominal cramps, diarrhea, metallic taste, nausea, and vomiting — all dose-related.

High doses over time can raise the risk of copper deficiency, which may lead to anemia. Vitamin D is generally safe at recommended doses.

Very high doses over time can cause toxicity, with symptoms including high calcium levels, weakened bones, and eye irritation. Both ingredients are considered likely safe in pregnancy and during breastfeeding at recommended amounts, though vitamin D in pregnancy should be used only under your doctor's guidance.

High-dose zinc in pregnancy is rated both likely safe and possibly unsafe — talk with your doctor before taking high amounts while pregnant.

Side effects, ingredient by ingredient Zinc Vitamin D

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Vitamin D, Zinc.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: heart-rhythm medications.
  • For scale: 765 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this lozenge, double-check with your doctor or pharmacist if you use quinolone or tetracycline antibiotics, cephalexin, or penicillamine — zinc can cut their absorption and effectiveness. Also flag heart drugs (verapamil, diltiazem, digoxin), thiazide diuretics, atorvastatin, or HIV medications like ritonavir or integrase inhibitors, where vitamin D can cause problems.

If your kidneys don't work well and you take aluminum-containing products, mention that too. Spacing your dose away from antibiotics (2–6 hours, depending on the type) may help, but your doctor or pharmacist is the one to plan that.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This lozenge may help if you're deficient in zinc or vitamin D, or if you're managing specific conditions like rickets or Wilson disease. If you take antibiotics, heart rhythm drugs, HIV medications, or cholesterol drugs, check your exact medications with your doctor or pharmacist before starting.

The probiotic strains here don't have interaction data available, so we can't tell you how they might affect your drugs. Your own doctor or pharmacist can review your full medication list and decide if this is right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 28, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Oral & Sinus Cinnamon Stick Flavor, straight from the product label.

Brand SimplyBiotix
Barcode (UPC) 678829292250
Net contents 30 Lozenge(s)
Market status On market
Date entered into DSLD May 28, 2019
DSLD ID 201971
Product type Other Combinations
Supplement form Lozenge
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Oral & Sinus Cinnamon Stick Flavor by SimplyBiotix, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Lozenge(s)
Maximum serving Sizes:
1 Lozenge(s)
Servings per container
30
UPC/BARCODE
678829292250
IngredientAmount% DV
Zinc5 mg45%
Vitamin D10 mcg50%
L. reuteri0 NP--
S. salivarius K120 NP--
Oral & Sinus Probiotic Blend40 mg--
S. salivarius M180 NP--

Other ingredients: Isomalt, Microcrystalline Cellulose, Stearic Acid, Dicalcium Phosphate, natural Cinnamon flavor, Stevia, natural Vanilla flavor

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General

SKU: BNT 02 L13000, 2017 R-1

General Statements

This Product Supports: Ear, Nose, and Throat Health Oral Health Immune Health

Immune Support

Helps keep your teeth, gums, and sinuses healthy

The Formula: This product is guaranteed for purity and labeled potency through the end of shelf life.

Formulation

This Product Is Free From: No Soy No GMOs No Gluten No Eggs No Peanuts/Tree Nuts No Sugar

Sugar free

Seals/Symbols

No Gluten

Suggested/Recommended/Usage/Directions

Suggested Use: Adults and children 4 years and older: Dissolve 1 lozenge in mouth once or twice daily and then swallow, ideally after brushing teeth.

Formula

Contains: Milk. Contains trace amounts of milk protein from the manufacturing process; however, suitable for individuals following lactose-restricted diets.

Contains BLIS K12 Contains BLIS M18

Precautions

Contains: Milk. Contains trace amounts of milk protein from the manufacturing process; however, suitable for individuals following lactose-restricted diets.

Keep out of reach of children.

FDA Statement of Identity

Dietary Supplement

Storage

Store bottle in a cool, dry place. After opening, store bottle with cap tightly closed.

Brand IP Statement(s)

BLIS, BLIS K12, AND BLIS M18 are trademarks of Blis Technologies Limited and are subject of USA patent nos. 6773912 and 7226590.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Oral & Sinus Cinnamon Stick Flavor by SimplyBiotix label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Oral & Sinus Cinnamon Stick Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Oral & Sinus Cinnamon Stick Flavor by SimplyBiotix

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Lozenge(s) Dosage formLozenge Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Zinc

Interacts with
67 drugs
5 mg per serving Form: Zinc Oxide

Zinc is an essential mineral that your body needs for immune function, wound healing, taste, and smell. Most people get enough from food, but suppleme...

Zinc monograph & interactions

Vitamin D

Interacts with
715 drugs
10 mcg per serving Form: Cholecalciferol

Vitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people,...

Vitamin D monograph & interactions

Oral & Sinus Probiotic Blend

40 mg per serving
  • › L. reuteri
  • › S. salivarius K12
  • › S. salivarius M18

Other (inactive) ingredients: Isomalt, Microcrystalline Cellulose, Stearic Acid, Dicalcium Phosphate, Natural Cinnamon flavor, Stevia, Natural Vanilla flavor. These complete the product’s ingredient list but are not active constituents.

Interaction report

Oral & Sinus Cinnamon Stick Flavor by SimplyBiotix Drug Interactions

Want to check YOUR meds against Oral & Sinus Cinnamon Stick Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
764Drugs
143 Moderate 621 Minor

Ingredients driving the most interactions

Vitamin D 715
Zinc 67

Individual Drug Interactions

The ingredients in Oral & Sinus Cinnamon Stick Flavor interact with 764 drugs. Click any drug to see the details.

2 of the 5 ingredients in Oral & Sinus Cinnamon Stick Flavor interact with drugs. Each result below shows which ingredient is responsible. Vitamin D Zinc

Each ingredient & the kinds of drugs it affects

For each ingredient in Oral & Sinus Cinnamon Stick Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin D8 drug types · 715 drugs

Aluminum

Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
The protein that transports calcium across the intestinal wall can also bind and transport aluminum. This protein is stimulated by vitamin D, which may therefore increase aluminum absorption. This mechanism may contribute to increased aluminum levels and toxicity in people with renal failure, when they take vitamin D and aluminum-containing phosphate binders chronically.

Likelihood Probable Evidence B
Atorvastatin (Lipitor)

Vitamin D might reduce absorption of atorvastatin.
A small, low-quality clinical study shows that taking vitamin D reduces levels of atorvastatin and its active metabolites by up to 55%. However, while atorvastatin levels decreased, total cholesterol, low-density lipoprotein (LDL) cholesterol, and high-density lipoprotein (HDL) cholesterol levels did not substantially change. Atorvastatin is metabolized in the gut by CYP3A4 enzymes, and researchers theorized that vitamin D might induce CYP3A4, causing reduced levels of atorvastatin. However, this proposed mechanism was not specifically studied.

Likelihood Probable Evidence B
Calcipotriene (Dovonex)

Taking calcipotriene with vitamin D increases the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with vitamin D supplements might increase the risk of hypercalcemia.

Likelihood Probable Evidence D
Digoxin (Lanoxin)

Theoretically, hypercalcemia induced by high-dose vitamin D can increase the risk of arrhythmia from digoxin.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and digoxin concurrently.

Likelihood Possible Evidence D
Diltiazem (Cardizem, Others)

Theoretically, hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of diltiazem for arrhythmia.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically this could also occur with diltiazem. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and diltiazem concurrently.

Likelihood Probable Evidence B
Thiazide Diuretics

Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Thiazide diuretics decrease urinary calcium excretion, which could lead to hypercalcemia if vitamin D supplements are taken concurrently. This has been reported in people being treated with vitamin D for hypoparathyroidism, and also in elderly people with normal parathyroid function who were taking a thiazide, vitamin D, and calcium-containing antacids daily.

Likelihood Probable Evidence D
Verapamil (Calan, Others)

Hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of verapamil for arrhythmia.
Hypercalcemia due to high doses of vitamin D can reduce the effectiveness of verapamil in atrial fibrillation. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and verapamil concurrently.

Likelihood Probable Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
There is some concern that vitamin D might induce CYP3A4. In vitro research suggests that vitamin D induces CYP3A4 transcription. Additionally, observational research has found that increased UV light exposure and serum vitamin D levels are associated with decreased serum levels of CYP3A4 substrates such as tacrolimus and sirolimus, while no association between UV light exposure or vitamin D levels and levels of mycophenolic acid, a non-CYP3A4 substrate, was found. A small, low-quality clinical study shows that taking vitamin D reduces levels of the CYP3A4 substrate atorvastatin and its active metabolites by up to 55%; however, the clinical effects of atorvastatin were not reduced. While researchers theorized that vitamin D might induce CYP3A4, this proposed mechanism was not specifically studied.

Likelihood Possible Evidence D
Vitamin D full monograph & interactions

Zinc10 drug types · 67 drugs

Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Theoretically, zinc might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide should be taken at least 2 hours before or 6 hours after zinc containing products.

Likelihood Probable Evidence D
Cephalexin (Keflex)

Zinc might decrease cephalexin levels by chelating with cephalexin in the gut and preventing its absorption.
A pharmacokinetic study shows that zinc sulfate 250 mg taken concomitantly with cephalexin 500 mg decreases peak levels of cephalexin by 31% and reduces the exposure to cephalexin by 27%. Also, taking zinc sulfate 3 hours before cephalexin decreases peak levels of cephalexin by 11% and reduces the exposure to cephalexin by 18%. By decreasing cephalexin levels, zinc might increase the risk of treatment failure. This effect does not occur when zinc is taken 3 hours after the cephalexin dose. To avoid an interaction, advise patients take zinc sulfate 3 hours after taking cephalexin.

Likelihood Probable Evidence B
Cisplatin (Platinol-Aq)

Theoretically, zinc might interfere with the therapeutic effects of cisplatin.
Animal research suggests that zinc stimulates tumor cell production of the protein metallothionein, which binds and inactivates cisplatin. It is not known whether zinc supplements or high dietary zinc intake can cause clinically significant interference with cisplatin therapy. Cisplatin might also increase zinc excretion.

Likelihood Possible Evidence D
Integrase Inhibitors

Theoretically, taking zinc along with integrase inhibitors might decrease the levels and clinical effects of these drugs.
Zinc is a divalent cation. Pharmacokinetic studies have shown that other divalent cations such as calcium and iron can decrease blood levels of the integrase inhibitor dolutegravir through chelation.

Likelihood Possible Evidence D
Penicillamine (Cuprimine, Depen)

Zinc might reduce the levels and clinical effects of penicillamine.
By forming an insoluble complex with penicillamine, zinc interferes with penicillamine absorption and activity. Zinc supplements reduce the efficacy of low-dose penicillamine (0.5-1 gram/day), but do not seem to affect higher doses (1-2.75 gram/day), provided dosing times are separated. Advise patients to take zinc and penicillamine at least 2 hours apart.

Likelihood Probable Evidence B
Quinolone Antibiotics

Zinc can decrease the levels and clinical effects of quinolones antibiotics.
Quinolones form complexes with zinc in the gastrointestinal tract, reducing absorption of both the quinolone and zinc if taken at the same time. Advise patients to take these drugs at least 2 hours before, or 4-6 hours after, zinc supplements.

Likelihood Probable Evidence B
Ritonavir (Norvir)

Zinc modestly reduces levels of ritonavir.
Clinical research shows that zinc might reduce serum ritonavir levels by chelating with ritonavir in the gut and preventing its absorption. In patients with HIV, ritonavir is taken with atazanavir to prevent the metabolism and increase the effects of atazanavir. A pharmacokinetic study shows that, in patients being treated with atazanavir/ritonavir, co-administration of zinc sulfate (Solvazinc tablets) 125 mg as a single dose or as multiple daily doses for 2 weeks reduces plasma levels of ritonavir by about 16%. However, atazanavir levels still remains high enough to prevent HIV virus replication. Therefore, the decrease in ritonavir levels is not likely to be clinically significant.

Likelihood Probable Evidence B
Tetracycline Antibiotics

Zinc might reduce levels of tetracycline antibiotics.
Tetracyclines form complexes with zinc in the gastrointestinal tract, which can reduce absorption of both the tetracycline and zinc when taken at the same time. Taking zinc sulfate 200 mg with tetracycline reduces absorption of the antibiotic by 30% to 40%. Demeclocycline and minocycline cause a similar interaction. However, doxycycline does not seem to interact significantly with zinc. Advise patients to take tetracyclines at least 2 hours before, or 4-6 hours after, zinc supplements to avoid any interactions.

Likelihood Probable Evidence B
Amiloride (Midamor)

Amiloride can modestly reduce zinc excretion and increase zinc levels.
Clinical research shows that amiloride can reduce urinary zinc excretion, especially at doses of 10 mg per day or more. This zinc-sparing effect can help to counteract zinc losses caused by thiazide diuretics, but it is unlikely to cause zinc toxicity at usual amiloride doses. The other potassium-sparing diuretics, spironolactone (Aldactone) and triamterene (Dyrenium), do not seem to have a zinc-sparing effect.

Likelihood Probable Evidence B
Atazanavir (Reyataz)

Zinc modestly reduces levels of atazanavir, although this effect does not seem to be clinically significant.
Clinical research shows that zinc might decrease serum atazanavir levels by chelating with atazanavir in the gut and preventing its absorption. Although a single dose of zinc sulfate (Solvazinc tablets) 125 mg orally does not affect atazanavir concentrations in patients being treated with atazanavir/ritonavir, co-administration of zinc sulfate 125 mg daily for 2 weeks reduces plasma levels of atazanavir by about 22% in these patients. However, despite this decrease, atazanavir levels still remain at high enough concentrations for the prevention of HIV virus replication.

Likelihood Probable Evidence B
Zinc full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Oral & Sinus Cinnamon Stick Flavor, from the product label.

SimplyBiotix

See all SimplyBiotix products
Name
Healthy Directions
City
Bethesda
State
MD
ZipCode
20817
Phone Number
(800) 618-1810
Web Address
SimplyBiotix.com
Pharmacist Counseling Corner

Oral & Sinus Cinnamon Stick Flavor by SimplyBiotix: Common Questions

Does Oral & Sinus Cinnamon Stick Flavor by SimplyBiotix interact with any medications?
Yes. Based on its ingredients, Oral & Sinus Cinnamon Stick Flavor has a known interaction with 764 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Oral & Sinus Cinnamon Stick Flavor contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is zinc for in this lozenge?
Zinc supports immune function and wound healing. It's effective for treating zinc deficiency and Wilson disease, and may help with acne and age-related eye problems, though the evidence for those is still building.
What does vitamin D do here?
Vitamin D helps your body absorb calcium and is essential for bone health. It's effective for rickets, soft bones (osteomalacia), kidney bone disease, low parathyroid function, and familial hypophosphatemia.
Can I take this if I'm pregnant?
Zinc and vitamin D are rated likely safe in pregnancy at recommended amounts, but vitamin D should be used only under your doctor's guidance when you're pregnant. The probiotic strains don't have pregnancy data on file, so check with your doctor or pharmacist before starting.
What side effects should I expect?
At recommended doses, zinc may cause a metallic taste, nausea, or diarrhea — these are dose-related. Vitamin D at recommended amounts is generally well tolerated. High doses of either can cause problems over time, so stick to normal amounts unless your doctor advises otherwise.
Is this safe for breastfeeding?
Both zinc and vitamin D are rated likely safe during breastfeeding at recommended amounts. We don't have safety data for the probiotic strains, so ask your doctor or pharmacist if you're nursing.
Can I take this with antibiotics?
Zinc can reduce how well certain antibiotics work, especially quinolones, tetracyclines, and cephalexin. Talk with your doctor or pharmacist before combining this lozenge with any antibiotic — spacing the doses several hours apart may help, but they'll need to advise you on your specific medication.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Oral & Sinus Cinnamon Stick Flavor label
Go deeper

The Full Monographs Behind Oral & Sinus Cinnamon Stick Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Zinc

Interacts with 67 drugs

Zinc is an essential mineral that your body needs for immune function, wound healing, taste, and smell. Most people get enough from food, but supplements can help correct or prevent a defici...

Read the full Zinc monograph → Herb & supplement monograph

Vitamin D

Interacts with 715 drugs

Vitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people, especially those with low sun exposure,...

Read the full Vitamin D monograph →
Sources

Sources & How We Checked

Oral & Sinus Cinnamon Stick Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 114 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Zinc 88 references
  1. Barceloux DG. Zinc. J Toxicol Clin Toxicol 1999;37:279-92.
  2. Eby GA, Davis DR, Halcomb WW. Reduction in duration of common colds by zinc gluconate lozenges in a double-blind study. Antimicrob Agents Chemother 1984;25:20-4. DOI
  3. Smith DS, Helzner EC, Nuttall CE Jr, et al. Failure of zinc gluconate in treatment of acute upper respiratory tract infections. Antimicrob Agents Chemother 1989;33:646-8. PubMed
  4. Blondeau JM. Expanded activity and utility of the new fluoroquinolones: a review. Clin Ther 1999;21:3-40. PubMed
  5. Reyes AJ, Olhaberry JV, Leary WP, et al. Urinary zinc excretion, diuretics, zinc deficiency and some side-effects of diuretics. S Afr Med J 1983;64:936-41.
  6. Kugelmas M. Preliminary observation: oral zinc sulfate replacement is effective in treating muscle cramps in cirrhotic patients. J Am Coll Nutr 2000;19:13-5. PubMed
  7. Hebel SK, ed. Drug Facts and Comparisons. 52nd ed. St. Louis: Facts and Comparisons, 1998.
  8. Chan S, Gerson B, Subramaniam S. The role of copper, molybdenum, selenium, and zinc in nutrition and health. Clin Lab Med 1998;18:673-85. DOI
  9. Brewer GJ, Yuzbasiyan-Gurkan V, Johnson V, et al. Treatment of Wilson's disease with zinc: XI. Interaction with other anticopper agents. J Am Coll Nutr 1993;12:26-30. PubMed
  10. Fosmire GJ. Zinc toxicity. Am J Clin Nutr 1990;51:225-7.
  11. Lomaestro BM, Bailie GR. Absorption interactions with fluoroquinolones. 1995 update. Drug Saf 1995;12:314-33. PubMed
  12. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  13. Seelig MS. Auto-immune complications of D-penicillamine - A possible result of zinc and magnesium depletion and of pyridoxine inactivation. J Am Coll Nutr 1982;1:207-14. PubMed
  14. Neuvonen PJ. Interactions with the absorption of tetracyclines. Drugs 1976;11:45-54.. PubMed
  15. Hirt M, Nobel S, Barron E. Zinc nasal gel for the treatment of common cold symptoms: A double-blind, placebo-controlled trial. Ear Nose Throat J 2000;79:778-82.. DOI
  16. Simkin PA. Oral zinc sulphate in rheumatoid arthritis. Lancet 1976;2:539-42. PubMed
  17. Wray D. A double-blind trial of systemic zinc sulfate in recurrent aphthous stomatitis. Oral Surg Oral Med Oral Pathol 1982;53:469-72. PubMed
  18. Douglas RM, Miles HB, Moore BW, et al. Failure of effervescent zinc acetate lozenges to alter the course of upper respiratory tract infections in Australian adults. Antimicrob Agents Chemother 1987;31:1263-5. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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