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Dietary supplement

Oregano Oil Ingredients & Drug Interactions

by Allergy Research Group

Oregano Oil label
See full label image
Softgel Capsule Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Oregano Oil against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Oregano Oil is a dietary supplement by Allergy Research Group with 2 active ingredients. Its ingredients are commonly taken for high cholesterol, digestive health and fiber, heart health support.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Oregano Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Oregano Oil by Allergy Research Group

Ask about any prescription or over-the-counter medication and we check it for interactions with Oregano Oil by Allergy Research Group — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Oregano Oil by Allergy Research Group

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This softgel contains 2 active ingredients: oregano oil and rice bran oil. Oregano oil is the concentrated extract from the oregano plant.

Rice bran oil comes from the outer layer of rice grains and is used in supplements for its nutrient profile. The capsule itself is made from gelatin, glycerin, and water.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Dyslipidemia — rated "Possibly Effective" (Rice Bran) (Natural Medicines).

The evidence for oregano oil's effectiveness isn't established in the data we hold. The product facts list several conditions—acne, bronchitis, asthma, headache, and upper respiratory infections—but for all of them the rating is insufficient reliable evidence to rate, meaning we don't have enough solid research to say whether it works.

Rice bran oil shows possibly effective evidence for dyslipidemia (high cholesterol levels), but possibly ineffective for colorectal cancer. For hair loss (alopecia areata), the evidence is insufficient.

The evidence, ingredient by ingredient Rice Bran Oregano

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oregano oil is well tolerated in food amounts, but concentrated supplements are stronger and less studied. The most common side effect is gastrointestinal upset.

Rare but serious allergic reactions, including anaphylaxis, have been reported in sensitive people. Topical oregano oil at concentrations above 1% can irritate mucous membranes.

Rice bran is generally well tolerated orally, though increasing bran intake can cause temporary abdominal discomfort, bloating, and irregular bowel habits when you first start. Allergic reactions to rice bran are rare but serious—anaphylaxis has been documented.

During pregnancy, oregano in medicinal or supplement amounts is possibly unsafe; food amounts are likely fine. There isn't enough data on oregano supplements during breastfeeding to know either way, so stick to food amounts.

Rice bran is likely safe in pregnancy and lactation.

Side effects, ingredient by ingredient Rice Bran Oregano

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Oregano.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take blood thinners (anticoagulants) or antiplatelet drugs like warfarin, clopidogrel, or aspirin—oregano oil may increase bleeding risk. Also check if you take diabetes medications, since oregano oil might lower blood sugar further and cause hypoglycemia.

No interactions are documented for rice bran oil.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help with high cholesterol, though the evidence is modest. The main caution: if you take blood thinners or diabetes medications, you need to check with your doctor or pharmacist before starting it—oregano oil can theoretically increase bleeding risk and lower blood sugar.

If you've had allergic reactions to oregano or rice, avoid it. Talk it over with your own doctor or pharmacist before you begin.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Oregano Oil, straight from the product label.

Brand Allergy Research Group
Barcode (UPC) 713947738508
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Nov 21, 2018
DSLD ID 183471
Product type Botanical With Nutrients
Supplement form Softgel Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Oregano Oil by Allergy Research Group, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
30
UPC/BARCODE
713947738508
IngredientAmount% DV
Rice Bran Oil100 mg--
Oregano Oil200 mg--

Other ingredients: Gelatin, Glycerin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Pure essential oil of oregano derived from Origanum vulare, containing 60% carvacrol.

Suggested/Recommended/Usage/Directions

Suggested use As a dietary supplement, 1 or 2 softgels daily with meals, or as directed by a healthcare practitioner.

Storage

Keep in a cool, dry place, tightly capped.

General

Rev. 005

FDA Statement of Identity

Dietary Supplement

Formulation

Hypoallergenic

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Oregano Oil by Allergy Research Group label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Oregano Oil label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Oregano Oil by Allergy Research Group

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Rice Bran Oil

No known
interactions
100 mg per serving

Rice bran is the nutrient-rich outer layer of the rice grain and is a good source of fiber, healthy fats, and plant compounds. It is most studied for...

Rice Bran Oil monograph & interactions

Oregano Oil

Interacts with
208 drugs
200 mg per serving Form: Carvacrol

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacr...

Oregano Oil monograph & interactions

Other (inactive) ingredients: Gelatin, Glycerin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Oregano Oil by Allergy Research Group Drug Interactions

Want to check YOUR meds against Oregano Oil?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Oregano Oil 208

Individual Drug Interactions

The ingredients in Oregano Oil interact with 208 drugs. Click any drug to see the details.

1 of the 2 ingredients in Oregano Oil interact with drugs. Each result below shows which ingredient is responsible. Oregano Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Oregano Oil with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Oregano Oil2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aristolochic acid isolated from oregano leaves has antithrombin activity. It has also been reported that oregano oil inhibits arachidonic acid-induced, and ADP-induced, platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, oregano might increase the risk for hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research shows that oregano extracts might lower blood glucose levels.

Likelihood Possible Evidence D
Oregano Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Oregano Oil, from the product label.

Allergy Research Group

See all Allergy Research Group products
Name
Allergy Research Group
City
Alameda
State
CA
ZipCode
94502
Phone Number
510-263-2000
Web Address
www.allergyresearchgroup.com
Pharmacist Counseling Corner

Oregano Oil by Allergy Research Group: Common Questions

Does Oregano Oil by Allergy Research Group interact with any medications?
Yes. Based on its ingredients, Oregano Oil has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Oregano Oil contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
Oregano oil in supplement amounts is possibly unsafe during pregnancy; food amounts of oregano are likely fine. Rice bran is likely safe. Because there isn't enough data on the oregano oil dose in this product, talk with your doctor or pharmacist before you take it while pregnant.
Is it safe to breastfeed while taking this?
There isn't enough safety data on oregano oil supplements during breastfeeding, so the data advises sticking to food amounts. Rice bran is likely safe. Talk with your doctor or pharmacist about whether this product is right for you while nursing.
What side effects might I notice?
The most common side effect is gastrointestinal upset from the oregano oil. If you're new to rice bran, you might have temporary bloating, gas, or loose stools. Serious allergic reactions like anaphylaxis are rare but have been reported.
Can I take this if I have a rice allergy?
No—this product contains rice bran oil, which can trigger allergic reactions in sensitive people, including rare but serious anaphylaxis. If you've had any allergic reaction to rice, avoid this supplement.
Does oregano oil really work for what it claims?
The facts we have don't show reliable evidence that oregano oil works for acne, bronchitis, asthma, headache, or upper respiratory infections. The evidence just isn't there yet.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Oregano Oil is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Oregano Oil label
Go deeper

The Full Monographs Behind Oregano Oil’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Rice Bran

Rice bran is the nutrient-rich outer layer of the rice grain and is a good source of fiber, healthy fats, and plant compounds. It is most studied for helping lower cholesterol, but for most...

Read the full Rice Bran monograph → Herb & supplement monograph

Oregano

Interacts with 208 drugs

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacrol. While lab studies suggest it may hav...

Read the full Oregano monograph →
Sources

Sources & How We Checked

Oregano Oil's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 19 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Rice Bran 7 references
  1. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  2. Fujiwaki T, Furusho K. The effects of rice bran broth bathing in patients with atopic dermatitis. Acta Paediatr Jpn 1992;34:505-10.
  3. Uenotsuchi T, Satoh E, Kiryu H, Yano Y. Pyemotes dermatitis caused by indirect contact with husk rice. Br J Dermatol 2000;143:680-2. DOI
  4. Satoh R, Tsuge I, Tokuda R, Teshima R. Analysis of the distribution of rice allergens in brown rice grains and of the allergenicity of products containing rice bran. Food Chem. 2019;276:761-767. PubMed
  5. Togashi Y, Inomata N, Suzuki A, Hakuta A, Aihara M. Pediatric case with rice bran allergy induced by epicutaneous sensitization in a family rice shop. Allergol Int. 2019;68(1):117-118. PubMed
  6. So WKW, Chan JYW, Law BMH, et al. Effects of a Rice Bran Dietary Intervention on the Composition of the Intestinal Microbiota of Adults with a High Risk of Colorectal Cancer: A Pilot Randomised-Controlled Trial. Nutrients 2021;13(2):526. PubMed
  7. Haneda Y, Kadowaki S, Furui M, Taketani T. A pediatric case of food-dependent exercise-induced anaphylaxis due to rice bran. Asia Pac Allergy 2021;11(1):e4. PubMed

See these in context on the Rice Bran monograph →

Oregano 12 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Benito M, Jorro G, Morales C, et al. Labiatae allergy: systemic reactions due to ingestion of oregano and thyme. Ann Allergy Asthma Immunol 1996;76:416-8. PubMed
  3. Chevallier A. Encyclopedia of Herbal Medicine. 2nd ed. New York, NY: DK Publ, Inc., 2000.
  4. Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
  5. Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290.
  6. Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
  7. Goun, E., Cunningham, G., Solodnikov, S., Krasnykch, O., and Miles, H. Antithrombin activity of some constituents from Origanum vulgare. Fitoterapia 2002;73(7-8):692-694. PubMed
  8. Lemhadri, A., Zeggwagh, N. A., Maghrani, M., Jouad, H., and Eddouks, M. Anti-hyperglycaemic activity of the aqueous extract of Origanum vulgare growing wild in Tafilalet region. J Ethnopharmacol. 2004;92(2-3):251-256. PubMed
  9. McCue, P., Vattem, D., and Shetty, K. Inhibitory effect of clonal oregano extracts against porcine pancreatic amylase in vitro. Asia Pac.J Clin.Nutr. 2004;13(4):401-408.
  10. Ragi, J., Pappert, A., Rao, B., Havkin-Frenkel, D., and Milgraum, S. Oregano extract ointment for wound healing: a randomized, double-blind, petrolatum-controlled study evaluating efficacy. J.Drugs Dermatol. 2011;10(10):1168-1172.
  11. Singletary K. Oregano: overview of the literature on health benefits. Nutrition Today 2010;45(3):129-38.
  12. Silva MLAE, Lucarini R, Dos Santos FF, et al. Hypoglycemic effect of rosmarinic acid-rich infusion (RosCE) from Origanum vulgare in alloxan-induced diabetic rats. Nat Prod Res 2022;36(17):4525-4531.

See these in context on the Oregano monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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