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Dietary supplement

Organic Beet Root Extract Powder 400 mg Ingredients & Drug Interactions

by BulkSupplements.com

Organic Beet Root Extract Powder 400 mg label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Oct 7, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Organic Beet Root Extract Powder 400 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Organic Beet Root Extract Powder 400 mg is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for high blood pressure, exercise and athletic performance, heart and circulation support.Based on those ingredients, 863 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Beet Root Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Organic Beet Root Extract Powder 400 mg by BulkSupplements.com

Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Beet Root Extract Powder 400 mg by BulkSupplements.com — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Organic Beet Root Extract Powder 400 mg by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Oct 8, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient, beet root extract, at 400 mg. Its notable components in the data we hold are nitrates, which can widen blood vessels, and betanin, the major red pigment in beet.

The only inactive ingredient listed is maltodextrin.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Beet's overall clinical evidence instead.

Moderate

Some clinical evidence supports Beet for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Athletic performance — rated "Possibly Effective" (Natural Medicines).
  • On file: Exercise-induced muscle soreness — rated "Possibly Effective" (Natural Medicines).

Beet root extract is rated possibly effective for athletic performance and for exercise-induced muscle soreness. It is rated possibly ineffective for chronic obstructive pulmonary disease (COPD).

For dyslipidemia and cognitive function, the reliable evidence is insufficient to rate.

The evidence, ingredient by ingredient Beet

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beet as a food is generally well tolerated, but the data we hold says concentrated supplements lack adequate safety data, so use caution. The most common adverse effects are red stools and red urine, which the data describes as not harmful.

Black stools have been reported, including in a 79-year-old man taking apixaban and clopidogrel, who had nausea and vomiting; reviewers judged an upper gastrointestinal bleed unlikely in that case. Rare serious effects include low blood calcium (hypocalcemia) and kidney damage when large amounts are taken.

Our data has no usable pregnancy entry for this ingredient, and the breastfeeding entry is blank, so there isn't enough information to say either way. Talk with your own doctor or pharmacist about pregnancy or breastfeeding.

Side effects, ingredient by ingredient Beet

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beet.
  • The most serious interaction on file is rated Moderate.
  • For scale: 864 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check medications cleared by the liver enzyme CYP3A4 first, which are rated Moderate. Blood pressure medicines (antihypertensives) and drugs cleared by CYP1A2 are both rated Minor.

Blood thinners are not listed as an interaction category, but a case report describes black stools in a patient taking apixaban and clopidogrel, so review your exact medications with your own doctor or pharmacist.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Beet root extract may be of interest to people looking into athletic performance or exercise-related muscle soreness, where the evidence is rated possibly effective. If you take medications cleared by CYP3A4, blood pressure medicines, or other drugs in the interaction list, be especially careful and talk it over with your own doctor or pharmacist before starting.

If you are pregnant or breastfeeding, talk with your own healthcare provider, since our data doesn't settle that question.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic Beet Root Extract Powder 400 mg, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X002I79A8H
Net contents 1 Kilogram(s); 35.3 Ounce(s)
Market status On market
Date entered into DSLD Feb 23, 2025
DSLD ID 329954
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic Beet Root Extract Powder 400 mg by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
400 mL
Maximum serving Sizes:
400 mL
Servings per container
2500
UPC/BARCODE
X002I79A8H
IngredientAmount% DV
Beet Root Extract400 mg--

Other ingredients: Maltodextrin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Organic Beet Root Extract Powder 400 mg per serving

Brand IP Statement(s)

Bulksupplements.com Clean & pure bulk supplements

Seals/Symbols

USDA Organic

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 400 mg (about 1/5 tsp) once or twice daily or as directed by a physician.

Formulation

Free of: Added sugar, soy, dairy, yeast, gluten

Certified organic by: Organic Certifiers, Inc.

General Statements

Use an accurate milligram scale.

New

Storage

Contents are sold by weight, not volume. Settling may occur. Store in a dry, cool place

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Organic Beet Root Extract Powder 400 mg by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Organic Beet Root Extract Powder 400 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Organic Beet Root Extract Powder 400 mg by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size400 mL Dosage formPowder Servings per container2500 Amounts shown are per serving.

Beet Root Extract

Interacts with
863 drugs
400 mg per serving

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some peopl...

Beet Root Extract monograph & interactions

Other (inactive) ingredients: Maltodextrin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Organic Beet Root Extract Powder 400 mg by BulkSupplements.com Drug Interactions

Want to check YOUR meds against Organic Beet Root Extract Powder 400 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
863Drugs
645 Moderate 218 Minor

Ingredients driving the most interactions

Beet Root Extract 863

Individual Drug Interactions

The ingredients in Organic Beet Root Extract Powder 400 mg interact with 863 drugs. Click any drug to see the details.

1 of the 1 ingredient in Organic Beet Root Extract Powder 400 mg interact with drugs. Each result below shows which ingredient is responsible. Beet Root Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Organic Beet Root Extract Powder 400 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Beet Root Extract3 drug types · 863 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, beet might increase the levels of CYP3A4 substrates.
In vitro research suggests that betanin, the major pigment in beet, competitively inhibits CYP3A4 in a dose-dependent manner similarly to strong CYP3A4 inhibitor ketoconazole.

Likelihood Possible Evidence D
Antihypertensive Drugs

Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure. However, a study published in the European Journal of Clinical Nutrition using concentrated beetroot juice found no significant impact on blood pressure or heart rate in different age groups. Other small clinical studies suggest that while beet consumption might transiently lower blood pressure due to vessel dilation, there's no consistent evidence of a lasting effect. Overall, the theoretical risk of reduced blood pressure due to beet's nitrate content exists, but studies generally indicate a low and temporary impact rather than a sustained decrease.

Likelihood Possible Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research suggests that beet induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Beet Root Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Organic Beet Root Extract Powder 400 mg, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
bulksupplements.com
Pharmacist Counseling Corner

Organic Beet Root Extract Powder 400 mg by BulkSupplements.com: Common Questions

Does Organic Beet Root Extract Powder 400 mg by BulkSupplements.com interact with any medications?
Yes. Based on its ingredients, Organic Beet Root Extract Powder 400 mg has a known interaction with 863 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Organic Beet Root Extract Powder 400 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant?
Our data has no usable pregnancy entry for beet root extract, so there isn't enough information to say either way. Talk with your own doctor or pharmacist for advice about your situation.
Will this make my stool or urine change color?
Yes, red stools and red urine are the most common adverse effects. The data describes the red coloring of stools as not harmful.
Does beet root extract work for athletic performance?
It is rated possibly effective for athletic performance and for exercise-induced muscle soreness. The evidence is not rated as conclusive.
Does it help with COPD?
It is rated possibly ineffective for chronic obstructive pulmonary disease (COPD) in the data we hold.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic Beet Root Extract Powder 400 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic Beet Root Extract Powder 400 mg label
Go deeper

The Full Monographs Behind Organic Beet Root Extract Powder 400 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Beet

Interacts with 863 drugs

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some people. It is generally safe as a food, but s...

Read the full Beet monograph →
Sources

Sources & How We Checked

Organic Beet Root Extract Powder 400 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beet 10 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Siervo M, Lara J, Ogbonmwan I, Mathers JC. Inorganic nitrate and beetroot juice supplementation reduces blood pressure in adults: a systematic review and meta-analysis. J Nutr 2013;143:818-26. PubMed
  3. Wylie LJ, Kelly J, Bailey SJ, et al. Beetroot juice and exercise: pharmacodynamic and dose-response relationships. J Appl Physiol (1985). 2013;115(3):325-36. PubMed
  4. Garnacho-Castaño MV, Palau-Salvà G, Cuenca E, et al. Effects of a single dose of beetroot juice on cycling time trial performance at ventilatory thresholds intensity in male triathletes. J Int Soc Sports Nutr. 2018;15(1):49. PubMed
  5. Rasica L, Porcelli S, Marzorati M, et al. Ergogenic effects of beetroot juice supplementation during severe-intensity exercise in obese adolescents. Am J Physiol Regul Integr Comp Physiol. 2018;315(3):R453-R460. PubMed
  6. Henrohn D, Björkstrand K, Lundberg JO, et al. Effects of oral supplementation with nitrate-rich beetroot juice in patients with pulmonary arterial hypertension-results from BEET-PAH, an exploratory randomized, double-blind, placebo-controlled, crosso
  7. Serra-Payá N, Garnacho-Castaño MV, Sánchez-Nuño S, et al. The relationship between resistance exercise performance and ventilatory efficiency after beetroot juice intake in well-trained athletes. Nutrients 2021;13(4):1094. PubMed
  8. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
  9. Lim SH, Bae S, Lee HS, Han HK, Choi CI. Effect of Betanin, the Major Pigment of Red Beetroot (Beta vulgaris L.), on the Activity of Recombinant Human Cytochrome P450 Enzymes. Pharmaceuticals (Basel) 2023;16(9):1224. PubMed
  10. Oscherwitz M, Tamayo RM, Heudebert A, Centor R. A Case of Pseudo-Hematochezia from Beet Supplement Ingestion. Am J Med 2023;136(9):e177-e178. PubMed

See these in context on the Beet monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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