Interactions on record — worth a quick check against your medications. Based on 1 of 10 ingredients. Check your meds →
Dietary supplement

Organic Cold Pressed Walnut Oil Ingredients & Drug Interactions

by Higher Nature

Organic Cold Pressed Walnut Oil label
See full label image
Liquid Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Organic Cold Pressed Walnut Oil against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Organic Cold Pressed Walnut Oil is a dietary supplement by Higher Nature with 10 active ingredients. Its ingredients are commonly taken for heart health, healthy cooking fat, skin moisturizing.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Oleic Acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Organic Cold Pressed Walnut Oil by Higher Nature

Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Cold Pressed Walnut Oil by Higher Nature — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Organic Cold Pressed Walnut Oil by Higher Nature

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 6 of its 7 active ingredients.

This product contains 7 ingredients, with oleic acid as a key active component — a monounsaturated fat that plays a central role in how your body processes cholesterol and manages blood sugar. The other active fatty acids (linoleic acid, alpha-linolenic acid, saturates, monounsaturates, and polyunsaturates) are the natural fats that make up walnut oil itself.

Salt is also listed as an active ingredient. The inactive ingredient is the organically grown, unrefined, cold-pressed walnut oil that forms the base of the product.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Oleic Acid's overall clinical evidence instead.

Moderate

Some clinical evidence supports Oleic Acid for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Coronary heart disease (CHD) — rated "Possibly Effective" (Natural Medicines).
  • On file: Hypercholesterolemia — rated "Possibly Effective" (Natural Medicines).

The evidence in our data speaks to oleic acid's role in managing cholesterol and heart health. Oleic acid is rated possibly effective for high cholesterol (hypercholesterolemia) and possibly effective for reducing the risk of coronary heart disease (CHD).

This rating means preliminary research supports the idea, but larger or more rigorous trials are needed to be sure. We don't hold effectiveness data for the other ingredients in this product.

The evidence, ingredient by ingredient Oleic Acid

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oleic acid from food sources — like the amounts in olive oil — is generally well tolerated and recognized as safe. However, the safety data we hold notes that concentrated supplements of oleic acid have not been well studied in pregnancy or while breastfeeding.

Food-level amounts are considered safe during these times, but supplement-strength doses lack good safety evidence. Talk with your doctor or pharmacist about whether this product is right for you if you're pregnant, planning to become pregnant, or breastfeeding.

No adverse effects are documented in our data for this product.

Side effects, ingredient by ingredient Oleic Acid

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Oleic Acid.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs (such as metformin, sulfonylureas, or insulin), talk with your doctor or pharmacist before adding this product — oleic acid may increase how well these medications lower your blood sugar. We could not check several other ingredients in this product against our interaction data, so it's worth running your full medication list through the tool on this page before you start.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and some safety-information gaps remain.

If you're interested in supporting heart health and cholesterol management through a walnut oil supplement, this product offers oleic acid that preliminary research suggests may help. The main caution is if you take antidiabetes medications — you'll want to discuss this with your doctor or pharmacist first, since oleic acid may strengthen their blood-sugar-lowering effect.

Pregnancy and breastfeeding warrant a conversation with your healthcare provider about safety before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic Cold Pressed Walnut Oil, straight from the product label.

Brand Higher Nature
Barcode (UPC) 5031013105890
Net contents 200 mL
Market status On market
Date entered into DSLD Jun 24, 2020
DSLD ID 228205
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses Nutrient, All Other
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic Cold Pressed Walnut Oil by Higher Nature, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 mL
Maximum serving Sizes:
10 mL
UPC/BARCODE
5031013105890
IngredientAmount% DV
Sugar0 Gram(s), 0 Gram(s)--
Salt0 Gram(s), 0 Gram(s)--
Carbohydrates0 Gram(s), 0 Gram(s)--
Protein0 Gram(s), 0 Gram(s)--
Energy0 NP2.1%
Linoleic Acid2.6 Gram(s), 53 Gram(s)--
Oleic Acid1.1 Gram(s), 22 Gram(s)--
Alpha-Linolenic Acid0.52 Gram(s), 10 Gram(s)--
Saturates0.4 Gram(s), 8 Gram(s)2%, 40%
Total Fat4.75 Gram(s), 95 Gram(s)6.8%, 135.7%
Monounsaturates1.2 Gram(s), 24 Gram(s)--
Polyunsaturates3.15 Gram(s), 63 Gram(s)--

Other ingredients: organically grown unrefined cold pressed Walnut Oil

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

RI = Reference Intake of an average adult (8400kJ/ 2000kcal). This pack provides 40 x 5ml portions.

This PET jar is 100% stable, non toxic and non-reactive with oils.

Omega Excellence

This product is not tested on animals.

Packaged in a protective atmosphere. Best before end: see base.

Bottle 1 PET Lid 5 PP

Formulation

Does Not Contain: Sugar, salt, starch, soya, wheat, gluten, maize, corn, yeast, lactose, dairy products, artificial preservatives, colours or flavourings.

Vegan

This tasty 100% Certified Organic Cold Pressed Walnut Oil is extracted from superior quality, organically grown, raw walnuts. Carefully cold pressed and filtered to create a delicate, soft-yellow oil with a distinctive, sweet walnut flavour.

This tasty 100% Certified Organic Cold Pressed Walnut Oil is extracted from superior quality, organically grown, raw walnuts. Carefully cold pressed and filtered to create a delicate, soft-yellow oil with a distinctive, sweet walnut flavour.

Suitable for vegetarians and vegans.

Formula

Light oil with distinctive nutty taste Rich in healthy omegas

Suggested/Recommended/Usage/Directions

Directions: Use with salads, vegetables, dips, desserts, cooked pasta and rice. Not suitable for frying or baking. A healthy daily serving would be 1-2 teaspoons (5-10ml) (adults and children over 4 years).

Seals/Symbols

Organic Food Federation Certified Organic GB-ORB-04 Non EU Agriculture

Precautions

Contains nut oil.

Storage

Store in a cool, dark place. Refrigerate after opening and consume within 6 weeks.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Organic Cold Pressed Walnut Oil by Higher Nature label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Organic Cold Pressed Walnut Oil label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Organic Cold Pressed Walnut Oil by Higher Nature

These are the 10 active ingredients this product is made of. Select any to open its full monograph.

Serving size5 mL Dosage formLiquid Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Salt

0 Gram(s) per serving

Carbohydrates

0 Gram(s) per serving
  • › Sugar

Protein

0 Gram(s) per serving

Energy

0 NP per serving

Linoleic Acid

2.6 Gram(s) per serving

Oleic Acid

Interacts with
86 drugs
1.1 Gram(s) per serving

Oleic acid is a heart-healthy monounsaturated fat found mainly in olive oil, canola oil, avocados, and nuts. As part of a Mediterranean-style diet, it...

Oleic Acid monograph & interactions

Alpha-Linolenic Acid

0.52 Gram(s) per serving

Saturates

0.4 Gram(s) per serving

Monounsaturates

1.2 Gram(s) per serving

Polyunsaturates

3.15 Gram(s) per serving

Other (inactive) ingredients: Organically grown unrefined cold pressed Walnut Oil. These complete the product’s ingredient list but are not active constituents.

Interaction report

Organic Cold Pressed Walnut Oil by Higher Nature Drug Interactions

Want to check YOUR meds against Organic Cold Pressed Walnut Oil?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Oleic Acid 86

Individual Drug Interactions

The ingredients in Organic Cold Pressed Walnut Oil interact with 86 drugs. Click any drug to see the details.

1 of the 10 ingredients in Organic Cold Pressed Walnut Oil interact with drugs. Each result below shows which ingredient is responsible. Oleic Acid

Each ingredient & the kinds of drugs it affects

For each ingredient in Organic Cold Pressed Walnut Oil with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Oleic Acid1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, oleic acid might increase the effects of antidiabetes drugs. Preliminary clinical research in patients with type 2 diabetes taking oral hypoglycemic drugs shows that eating a diet rich in oleic acid from olive oil decreases fasting blood glucose levels when compared to eating a diet rich in linoleic acid from sunflower oil. It is unknown if taking oleic acid supplements would have this effect or if this change is clinically significant. Until more is known, use caution. Dose adjustment may be necessary. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, metformin (Glucophage), pioglitazone (Actos), rosiglitazone (Avandia), and others.

Likelihood Possible Evidence B
Oleic Acid full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Organic Cold Pressed Walnut Oil, from the product label.

Higher Nature

See all Higher Nature products
Name
Higher Nature
City
Burwash Common
State
East Sussex
ZipCode
TN19 7LX
Web Address
www.highernature.com
Pharmacist Counseling Corner

Organic Cold Pressed Walnut Oil by Higher Nature: Common Questions

Does Organic Cold Pressed Walnut Oil by Higher Nature interact with any medications?
Yes. Based on its ingredients, Organic Cold Pressed Walnut Oil has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Organic Cold Pressed Walnut Oil contains 10 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is oleic acid and why is it in walnut oil?
Oleic acid is a naturally occurring monounsaturated fat found in walnuts and other plant oils. It's part of the oil itself and may play a role in supporting heart health and cholesterol management.
Does this product actually help with cholesterol or heart disease?
The research we have on oleic acid rates it as possibly effective for high cholesterol and coronary heart disease — meaning early studies show promise, but we'd need larger trials to be confident. It's not a proven treatment, so talk with your doctor if you're considering it for those concerns.
Is it safe to take this while pregnant or breastfeeding?
Food-level amounts of oleic acid are considered safe during pregnancy and breastfeeding, but this product is a concentrated supplement, and concentrated doses haven't been well studied in these situations. Check with your doctor or pharmacist for personalized advice.
What are the inactive ingredients, and are there fillers?
The inactive ingredient listed is the organically grown, unrefined, cold-pressed walnut oil itself. We don't have data on other fillers, binders, or capsule materials that may be present.
Can I take this if I'm on medication for diabetes?
Not without checking first. Oleic acid may strengthen the blood-sugar-lowering effect of antidiabetes drugs, which could cause your blood sugar to drop too low. Talk with your doctor or pharmacist before starting this product if you take any diabetes medication.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic Cold Pressed Walnut Oil is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic Cold Pressed Walnut Oil label
Go deeper

The Full Monographs Behind Organic Cold Pressed Walnut Oil’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Oleic Acid

Interacts with 86 drugs

Oleic acid is a heart-healthy monounsaturated fat found mainly in olive oil, canola oil, avocados, and nuts. As part of a Mediterranean-style diet, it is widely viewed as a healthier replace...

Read the full Oleic Acid monograph →
Sources

Sources & How We Checked

Organic Cold Pressed Walnut Oil's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 19 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Oleic Acid 19 references
  1. Madigan C, Ryan M, Owens D, et al. Dietary unsaturated fatty acids in type 2 diabetes: higher levels of postprandial lipoprotein on a linoleic acid-rich sunflower oil diet compared with an oleic acid-rich olive oil diet. Diabetes Care 2000;23:1472-7. PubMed
  2. Gillingham, L. G., Gustafson, J. A., Han, S. Y., Jassal, D. S., and Jones, P. J. High-oleic rapeseed (canola) and flaxseed oils modulate serum lipids and inflammatory biomarkers in hypercholesterolaemic subjects. Br J Nutr 2011;105(3):417-427. PubMed
  3. Jones PJ, Senanayake VK, Pu S, Jenkins DJ, Connelly PW, Lamarche B, Couture P, Charest A, Baril-Gravel L, West SG, Liu X, Fleming JA, McCrea CE, Kris-Etherton PM. DHA-enriched high-oleic acid canola oil improves lipid profile and lowers predicted cardiova
  4. Cater, N. B., Heller, H. J., and Denke, M. A. Comparison of the effects of medium-chain triacylglycerols, palm oil, and high oleic acid sunflower oil on plasma triacylglycerol fatty acids and lipid and lipoprotein concentrations in humans. Am.J Clin.Nutr PubMed
  5. Mozaffarian D, Clarke R. Quantitative effects on cardiovascular risk factors and coronary heart disease risk of replacing partially hydrogenated vegetable oils with other fats and oils. Eur J Clin Nutr. 2009;63(Suppl 2):S22-33. PubMed
  6. Cao Y, Hou L, Wang W. Dietary total fat and fatty acids intake, serum fatty acids and risk of breast cancer: A meta-analysis of prospective cohort studies. Int J Cancer. 2016;138(8):1894-904. doi: 10.1002/ijc.29938. PubMed
  7. FDA completes review of qualified health claim petition for oleic acid and the risk of coronary heart disease. November 2018. Available at: www.fda.gov/Food/NewsEvents/ConstituentUpdates/ucm624758.htm. Accessed January 25, 2019.
  8. Liu X, Kris-Etherton PM, West SG, et al. Effects of canola and high-oleic-acid canola oils on abdominal fat mass in individuals with central obesity. Obesity. 2016;24(11):2261-2268. PubMed
  9. Bowen KJ, Kris-Etherton PM, West SG, et al. Diets enriched with conventional or high-oleic acid canola oils lower atherogenic lipids and lipoproteins compared to a diet with a western fatty acid profile in adults with central adiposity. J Nutr. 2019;149(3 PubMed
  10. Steffen BT, Duprez D, Szklo M, Guan W, Tsai MY. Circulating oleic acid levels are related to greater risks of cardiovascular events and all-cause mortality: The Multi-Ethnic Study of Atherosclerosis. J Clin Lipidol. 2018;12(6):1404-1412. PubMed
  11. Banim PJ, Luben R, Khaw KT, Hart AR. Dietary oleic acid is inversely associated with pancreatic cancer - Data from food diaries in a cohort study. Pancreatology. 2018;18(6):655-660. PubMed
  12. Morin SJ, Gaziano JM, Djoussé L. Relation between plasma phospholipid oleic acid and risk of heart failure. Eur J Nutr. 2018;57(8):2937-2942. PubMed
  13. Samieri C, Féart C, Proust-Lima C, et al. Olive oil consumption, plasma oleic acid, and stroke incidence: the Three-City Study. Neurology. 2011;77(5):418-25. PubMed
  14. Compher CW, Kinosian BP, Rubesin SE, Ratcliffe SJ, Metz DC. Energy absorption is reduced with oleic acid supplements in human short bowel syndrome. JPEN J Parenter Enteral Nutr. 2009;33(1):102-8. PubMed
  15. Ben Fradj MK, Ouanes Y, Hadj-Taieb S, et al. Decreased oleic acid and marine n?-?3 polyunsaturated fatty acids in Tunisian patients with urothelial bladder cancer. Nutr Cancer. 2018;70(7):1043-1050.
  16. de Silva PS, Luben R, Shrestha SS, Khaw KT, Hart AR. Dietary arachidonic and oleic acid intake in ulcerative colitis etiology: a prospective cohort study using 7-day food diaries. Eur J Gastroenterol Hepatol. 2014;26(1):11-8. PubMed
  17. Higashi K, Shige H, Ito T, et al. Effect of a low-fat diet enriched with oleic acid on postprandial lipemia in patients with type 2 diabetes mellitus. Lipids. 2001;36(1):1-6. PubMed
  18. Lin HC, van Citters GW, Heimer F, Bonorris G. Slowing of gastrointestinal transit by oleic acid: a preliminary report of a novel, nutrient-based treatment in humans. Dig Dis Sci. 2001;46(2):223-9. PubMed
  19. Li D, Tong Y, Li Y. Associations between dietary oleic acid and linoleic acid and depressive symptoms in perimenopausal women: The Study of Women's Health Across the Nation. Nutrition. 2020 Mar;71:110602. PubMed

See these in context on the Oleic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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