Organic Coleus Ingredients & Drug Interactions
by Herbadiet
What is this page for?
First and foremost: checking Organic Coleus against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Organic Coleus is a dietary supplement by Herbadiet with 1 active ingredient. Its ingredients are commonly taken for weight management, asthma and breathing, high blood pressure.Based on those ingredients, 915 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Coleus. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Organic Coleus by Herbadiet
Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Coleus by Herbadiet — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Organic Coleus by Herbadiet
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Organic Coleus by Herbadiet contains one active ingredient: coleus, a plant extract. The capsule itself is made from vegetable cellulose, an inactive ingredient.
Does it work?
Not established
The evidence we hold doesn't establish that coleus is effective for any of the conditions listed — angina, asthma, cancer, congestive heart failure, eczema, or dry eye all have insufficient reliable evidence to rate. That doesn't mean coleus doesn't work; it means the research to support it isn't in our data.
How safe is it?
Well-documented data
Coleus is generally well tolerated when taken by mouth, though some people report gastrointestinal side effects — most often diarrhea, along with less common nausea, vomiting, or constipation. In a small number of trial participants, loose stools and increased bowel movements occurred; retrospective reports suggest about a 10% rate of GI adverse effects overall, with diarrhea accounting for most of them.
Because coleus can lower blood pressure and isn't well studied for long-term use, use it only with professional guidance. The safety data advises against use during pregnancy and while breastfeeding — there isn't enough information to know it's safe in those situations.
Meds to double-check
Major interaction found
Before taking Organic Coleus, check with your doctor or pharmacist if you take any of the following: nitrates or calcium channel blockers (heart medications) — rated Major risk — or blood pressure drugs, blood thinners (anticoagulants and antiplatelet drugs, including warfarin), or any medication your liver processes through CYP2C9 or CYP3A4 pathways — all Moderate risk. The research on coleus and liver metabolism is conflicting, so clarification from your own provider is important.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.
Coleus has too many documented interactions with common heart, blood pressure, and blood-thinning medications for you to add it without checking first with your own doctor or pharmacist. If you don't take any of those drug types, the evidence on whether it actually works for anything is still too thin to recommend it.
Talk it over with your healthcare provider before you start.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 19, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Organic Coleus, straight from the product label.
| Brand | Herbadiet |
|---|---|
| Barcode (UPC) | 880860948649 |
| Net contents | 60 V-Cap(s) |
| Market status | On market |
| Date entered into DSLD | Nov 19, 2021 |
| DSLD ID | 257912 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Organic Coleus by Herbadiet, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Herbadiet Organic Coleus is made with certified organic coleus forskohlii root powder. This full spectrum herb retains all the active constituents in nature intended balanced ratio. Encapsulating this goodness in our quick release, easy to swallow vegan capsules, guarantees you a premium quality nutritional supplement.
Formulation
Cardiovascular support Boosts metabolism Helps fight insomnia
Natural color variation may occur in this product
USDA Organic
100% natural Weight management
Non-GMO
Suitable for vegetarians and vegans
Free of preservatives, binders, gluten, artificial ingredients, dairy, soy, wheat, yeast
Every batch 3rd party lab tested
FDA Disclaimer Statement
These statements have not been evaluated by FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Precautions
Do not use if seal under the cap is broken or missing. Dietary supplement shouldn't be used as a substitute for a varied diet
Caution: If you are pregnant, breast feeding, or taking medications, consult your doctor before use.
Discontinue use and consult your doctor if any adverse reactions occur.
Keep out of reach of children.
Not for medicinal use
Storage
Store in cool, dry place
Seals/Symbols
fssai Lic. No.: 20817018000147 Vcaps Plus GMP Good Manufacturing Practice Quality Product
USDA Organic
General Statements
1% for the planet
License Number : 10018064001315
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions for Use: Take 2 capsules daily, preferably with meals or as directed by your physician.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Organic Coleus by Herbadiet label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Organic Coleus by Herbadiet
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Coleus
Interacts with915 drugs
Coleus is a plant from the mint family whose root contains a compound called forskolin, often marketed for weight loss, asthma, and heart health. Whil...
Coleus monograph & interactionsOther (inactive) ingredients: Vegetable Cellulose Shell. These complete the product’s ingredient list but are not active constituents.
Organic Coleus by Herbadiet Drug Interactions
HelloPharmacist Interaction Report
Organic Coleus by Herbadiet contains coleus, which has documented interactions with several medication types.
The most serious concerns are with nitrates and calcium channel blockers (heart medications), both rated Major — coleus may add to their effects on blood vessel dilation in the heart, potentially causing too much of a drop in blood pressure or strain on the heart.
Read the full breakdown — every affected drug type, severity by severity
Coleus also interacts at a Moderate level with blood pressure medications, blood thinners (anticoagulants and antiplatelet drugs including warfarin), and drugs your liver breaks down through two major enzyme pathways (CYP2C9 and CYP3A4 substrates). With blood pressure drugs, the concern is additive lowering of your blood pressure.
With blood thinners, coleus may increase bleeding and bruising risk. With the liver-metabolized drugs, coleus may either reduce how well they work or increase their levels in your blood, depending on which enzyme pathway is involved — and the research on coleus and CYP2C9 is conflicting, which adds uncertainty.
Additionally, no other interactions are documented in our data. Because this product affects so many medications, use the interaction checker below to search your exact prescriptions before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Organic Coleus?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Organic Coleus interact with 915 drugs. Click any drug to see the details.
1 of the 1 ingredient in Organic Coleus interact with drugs. Each result below shows which ingredient is responsible. Coleus
AmlodipineNorliqva
How Amlodipine interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusCytochrome P450 3a4 (cyp3a4) Substrates, Calcium Channel Blockers +1 Major
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Major
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Coleus + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusCalcium Channel Blockers, Antihypertensive Drugs +1 Major
Interaction Summary
Theoretically, combining coleus with calcium channel blockers might increase the coronary vasodilatory effects.
Read the full Coleus + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Major
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Coleus + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusCalcium Channel Blockers, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Major
Interaction Summary
Theoretically, combining coleus with calcium channel blockers might increase the coronary vasodilatory effects.
Read the full Coleus + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusAntihypertensive Drugs, Cytochrome P450 2c9 (cyp2c9) Substrates +2 Major
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Coleus + Amlodipine, Celecoxib interactionBepridilVascor
How Bepridil interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusCalcium Channel Blockers, Cytochrome P450 3a4 (cyp3a4) Substrates Major
Interaction Summary
Theoretically, combining coleus with calcium channel blockers might increase the coronary vasodilatory effects.
Read the full Coleus + Bepridil interactionDiltiazemAdizem-SR, Adizem-XL, Angitil SR, Angitil XL, Calcicard CR, Cardizem +23 more
How Diltiazem interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusCalcium Channel Blockers, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Major
Interaction Summary
Theoretically, combining coleus with calcium channel blockers might increase the coronary vasodilatory effects.
Read the full Coleus + Diltiazem interactionDiltiazem, EnalaprilTeczem
How Diltiazem, Enalapril interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusAntihypertensive Drugs, Calcium Channel Blockers +1 Major
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Coleus + Diltiazem, Enalapril interactionEnalapril Maleate, FelodipineLexxel
How Enalapril Maleate, Felodipine interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Major
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Coleus + Enalapril Maleate, Felodipine interactionFelodipinePlendil, Renedil
How Felodipine interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusCalcium Channel Blockers, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Major
Interaction Summary
Theoretically, combining coleus with calcium channel blockers might increase the coronary vasodilatory effects.
Read the full Coleus + Felodipine interactionGlyceryl TrinitrateNitronal
How Glyceryl Trinitrate interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusNitrates Major
Interaction Summary
Theoretically, combining coleus with nitrates might increase the coronary vasodilatory effects.
Read the full Coleus + Glyceryl Trinitrate interactionIsosorbide DinitrateAngitak, Cedocard Retard, Isoket, Isoket Retard, Isordil
How Isosorbide Dinitrate interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusNitrates Major
Interaction Summary
Theoretically, combining coleus with nitrates might increase the coronary vasodilatory effects.
Read the full Coleus + Isosorbide Dinitrate interactionIsosorbide Dinitrate, HydralazineBiDil
How Isosorbide Dinitrate, Hydralazine interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusNitrates, Antihypertensive Drugs Major
Interaction Summary
Theoretically, combining coleus with nitrates might increase the coronary vasodilatory effects.
Read the full Coleus + Isosorbide Dinitrate, Hydralazine interactionIsosorbide MononitrateAngeze, Angeze SR, Chemydur 60XL, Dynamin, Elantan, Elantan LA +13 more
How Isosorbide Mononitrate interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusNitrates Major
Interaction Summary
Theoretically, combining coleus with nitrates might increase the coronary vasodilatory effects.
Read the full Coleus + Isosorbide Mononitrate interactionIsradipineDynacirc CR
How Isradipine interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusAntihypertensive Drugs, Calcium Channel Blockers +1 Major
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Coleus + Isradipine interactionLercanidipine HydrochlorideZanidip
How Lercanidipine Hydrochloride interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusCalcium Channel Blockers, Antihypertensive Drugs +1 Major
Interaction Summary
Theoretically, combining coleus with calcium channel blockers might increase the coronary vasodilatory effects.
Read the full Coleus + Lercanidipine Hydrochloride interactionLevamlodipineConjupri
How Levamlodipine interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs +1 Major
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus + Levamlodipine interactionNicardipineCardene, Cardene IV, Cardene SR
How Nicardipine interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusCytochrome P450 3a4 (cyp3a4) Substrates, Calcium Channel Blockers +1 Major
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus + Nicardipine interactionNicorandilAprior, Dancor, Ikorel, Sigmart, Zynicor
How Nicorandil interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusNitrates Major
Interaction Summary
Theoretically, combining coleus with nitrates might increase the coronary vasodilatory effects.
Read the full Coleus + Nicorandil interactionNifedipineAdalat, Adalat CC, Adalat LA, Adalat PA, Adalat Retard, Adalat XL +15 more
How Nifedipine interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Major
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Coleus + Nifedipine interactionNisoldipineSular
How Nisoldipine interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusCalcium Channel Blockers, Antihypertensive Drugs +1 Major
Interaction Summary
Theoretically, combining coleus with calcium channel blockers might increase the coronary vasodilatory effects.
Read the full Coleus + Nisoldipine interactionNitrendipineCardif
How Nitrendipine interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusCalcium Channel Blockers, Cytochrome P450 3a4 (cyp3a4) Substrates Major
Interaction Summary
Theoretically, combining coleus with calcium channel blockers might increase the coronary vasodilatory effects.
Read the full Coleus + Nitrendipine interactionNitroglycerinGonitro, Nitro Time, Nitro-Bid, Nitrocine Timecaps, Nitrogard, Nitrogard SR +7 more
How Nitroglycerin interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusNitrates Major
Interaction Summary
Theoretically, combining coleus with nitrates might increase the coronary vasodilatory effects.
Read the full Coleus + Nitroglycerin interactionPentaerythritol TetranitratePeritrate, Peritrate SA
How Pentaerythritol Tetranitrate interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusNitrates Major
Interaction Summary
Theoretically, combining coleus with nitrates might increase the coronary vasodilatory effects.
Read the full Coleus + Pentaerythritol Tetranitrate interactionPerindopril Arginine, AmlodipinePrestalia
How Perindopril Arginine, Amlodipine interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs +1 Major
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus + Perindopril Arginine, Amlodipine interactionTelmisartan, AmlodipineTwynsta
How Telmisartan, Amlodipine interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Major
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Coleus + Telmisartan, Amlodipine interactionTrandolapril, VerapamilTarka
How Trandolapril, Verapamil interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Major
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Coleus + Trandolapril, Verapamil interactionVerapamilCalan, Calan SR, Covera HS, Isoptin, Isoptin SR, Veramil +3 more
How Verapamil interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusCytochrome P450 3a4 (cyp3a4) Substrates, Calcium Channel Blockers +1 Major
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus + Verapamil interactionAdo-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Organic Coleus — through 1 ingredient. Tap an ingredient for the detail:
ColeusCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus + Ado-trastuzumab Emtansine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Organic Coleus with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Coleus
Calcium Channel Blockers
Theoretically, combining coleus with calcium channel blockers might increase the coronary vasodilatory effects.
Forskolin, a constituent of coleus, and calcium channel blockers both cause coronary vasodilatory effects.
Nitrates
Theoretically, combining coleus with nitrates might increase the coronary vasodilatory effects.
Forskolin, a constituent of coleus, and nitrates both cause coronary vasodilatory effects.
Anticoagulant/Antiplatelet Drugs
Theoretically, concomitant use of coleus and anticoagulant or antiplatelet drugs might increase the risk of bruising and bleeding.
In vitro and animal research shows that forskolin, a constituent of coleus, can inhibit platelet aggregation and adhesion.
Antihypertensive Drugs
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Animal research shows that forskolin, a constituent of coleus, may lower blood pressure.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, taking coleus may affect drugs metabolized by CYP2C9 and increase the risk of adverse effects or reduce the effectiveness.
Research on the effect of coleus on CYP2C9 is conflicting. Some animal research shows that coleus extract can induce CYP2C9, while in vitro research shows that coleus can inhibit CYP2C9. Until more is known, advise patients that taking coleus might increase or decrease levels of drugs metabolized by CYP2C9.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
In vitro research shows that coleus can activate the nuclear receptor, pregnane X receptor (PXR), which results in increased expression of CYP3A4. Although the clinical significance of this is not known, use caution when considering concomitant use of coleus and other drugs affected by these enzymes.
Warfarin (Coumadin)
Theoretically, taking coleus may affect the metabolism of warfarin and increase the risk of adverse effects or reduce the effectiveness.
Some animal research shows that coleus extract can induce cytochrome P450 2C9 (CYP2C9), an enzyme that metabolizes warfarin. However, other in vitro research shows that coleus can inhibit CYP2C9. Theoretically, taking coleus with drugs metabolized by CYP2C9 might affect drug levels and the risk of adverse effects. Until more is known, advise patients that taking coleus might increase or decrease levels of warfarin.
Brand information
Manufacturer and brand details for Organic Coleus, from the product label.
Herbadiet
See all Herbadiet products- Name
- Arkure Health Care
- City
- Haryana
- State
- India
- Web Address
- www.herbadiet.in
Organic Coleus by Herbadiet: Common Questions
Does Organic Coleus by Herbadiet interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is coleus, and what is it supposed to do?
Can I take this if I'm pregnant or breastfeeding?
What are the side effects?
Is this safe to take long-term?
Why does this product interact with so many medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Organic Coleus is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Organic Coleus’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Organic Coleus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 16 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Coleus 16 references
- Baumann G, Felix S, Sattelberger U, Klein G. Cardiovascular effects of forskolin (HL-362) in patients with idiopathic congestiv cardiomyopathy. A comparative study with dobutamine and sodium nitroprusside. J Cardiovasc Pharmacol 1990;16:93-100.
- Kramer W, Thormann J, Kindler M, Schlepper M. Effects of forskolin on left ventricular function in dilated cardiomyopathy. Arzneimittelforschung 1987;37:364-7.
- Bauer K, Dietersdorfer F, Kaspar S, et al. Pharmacodynamic effects of inhaled dry powder formulations of fenoterol and colforsin in asthma. Clin Pharmacol Ther 1993;53:76-83. PubMed
- Christenson JT, Thulesius O, Nazzal MM. The effect of forskolin on blood flow, platelet metabolism, aggregation and ATP release. Vasa 1995;24:56-61.
- Agarwal KC, Zielinski BA, Maitra RS. Significance of plasma adenosine in the antiplatelet activity of forskolin: potentiation by dipyridamole and dilazep. Thromb Haemost 1989;61:106-10. DOI
- Agarwal KC, Parks RE. Forskolin: a potential antimetastatic agent. Int J Cancer 1983;32:801-4. PubMed
- Almeida, F. C. and Lemonica, I. P. The toxic effects of Coleus barbatus B. on the different periods of pregnancy in rats. J Ethnopharmacol 2000;73(1-2):53-60. PubMed
- Ding, X. and Staudinger, J. L. Induction of drug metabolism by forskolin: the role of the pregnane X receptor and the protein kinase a signal transduction pathway. J Pharmacol Exp Ther 2005;312(2):849-856. PubMed
- Staudinger, J. L., Ding, X., and Lichti, K. Pregnane X receptor and natural products: beyond drug-drug interactions. Expert.Opin Drug Metab Toxicol 2006;2(6):847-857. PubMed
- van Hecke, E., Hindryckx, P., Geuns, J. M., and Devriese, E. Airborne contact dermatitis from coleus in a housewife. Contact Dermatitis 1991;25(2):128-129. PubMed
- Schlepper, M., Thormann, J., and Mitrovic, V. Cardiovascular effects of forskolin and phosphodiesterase-III inhibitors. Basic Res Cardiol 1989;84 Suppl 1:197-212. PubMed
- Dooms-Goossens, A., Borghijs, A., Degreef, H., Devriese, E. G., and Geuns, J. M. Airborne contact dermatitis to Coleus. Contact Dermatitis 1987;17(2):109-110. PubMed
- Lindner, E., Dohadwalla, A. N., and Bhattacharya, B. K. Positive inotropic and blood pressure lowering activity of a diterpene derivative isolated from Coleus forskohli: Forskolin. Arzneimittelforschung 1978;28(2):284-289.
- Loftus HL, Astell KJ, Mathai ML, et al. Coleus forskohlii Extract Supplementation in Conjunction with a Hypocaloric Diet Reduces the Risk Factors of Metabolic Syndrome in Overweight and Obese Subjects: A Randomized Controlled Trial. Nutrients. 2015;7(11): PubMed
- Yokotani K, Chiba T, Sato Y, et al. Hepatic cytochrome P450 mediates interaction between warfarin and Coleus forskohlii extract in vivo and in vitro. J Pharm Pharmacol. 2012;64(12):1793-801.
- Nishijima C, Chiba T, Sato Y, Umegaki K. Nationwide Online Survey Enables the Reevaluation of the Safety of Coleus forskohlii Extract Intake Based on the Adverse Event Frequencies. Nutrients. 2019;11(4). pii: E866. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC