Interactions on record — worth a quick check against your medications. Based on 2 of 4 ingredients. Check your meds →
Dietary supplement

Organic Infants Liquid Probiotic Unflavored Ingredients & Drug Interactions

by Mary Ruth's

Organic Infants Liquid Probiotic Unflavored label
See full label image
Liquid Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Organic Infants Liquid Probiotic Unflavored against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Organic Infants Liquid Probiotic Unflavored is a dietary supplement by Mary Ruth's with 4 active ingredients. Its ingredients are commonly taken for digestive health and regularity, irritable bowel syndrome (ibs), diarrhea (including antibiotic-related).Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bifidobacterium longum infantis, Bifidobacterium bifidum. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Organic Infants Liquid Probiotic Unflavored by Mary Ruth's

Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Infants Liquid Probiotic Unflavored by Mary Ruth's — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Organic Infants Liquid Probiotic Unflavored by Mary Ruth's

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 4 active ingredients.
  • “Proprietary Probiotic Blend” is a proprietary blend — the label gives one combined amount (250 mg) without saying how much of each component you get.

This liquid contains four active probiotic ingredients: Bifidobacterium longum infantis, Bifidobacterium bifidum, Bifidobacterium animalis lactis, and Lactobacillus reuteri. These are live beneficial bacteria meant to support digestive and immune health in infants.

The product is formulated in a liquid base with purified water and alfalfa as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: digestive health and gut balance for infants.
  • We looked for evidence on: Antibiotic-associated diarrhea, Colic, Constipation, Diarrhea, Irritable bowel syndrome (IBS), Necrotizing enterocolitis (NEC) — and 4 related terms.
  • The strongest evidence on file: Bifidobacterium Bifidum is rated "Possibly Effective" for Irritable bowel syndrome (IBS) (Natural Medicines).
  • Also on file: Bifidobacterium Bifidum is rated "Insufficient Reliable Evidence To Rate" for Antibiotic-associated diarrhea, Constipation, Radiation-induced diarrhea, Necrotizing enterocolitis (NEC), and more.
  • Also on file: Bifidobacterium Longum is rated "Insufficient Reliable Evidence To Rate" for Antibiotic-associated diarrhea.

Evidence for Bifidobacterium bifidum shows it's possibly effective for irritable bowel syndrome (IBS) and respiratory tract infections. For Bifidobacterium longum infantis, the data we hold rates age-related cognitive decline, hay fever, antibiotic-associated diarrhea, anxiety, asthma, and athletic performance as having insufficient reliable evidence — meaning the science isn't established enough yet to say whether it works for those conditions.

We have no effectiveness data on file for the other two bacterial strains in this product.

The evidence, ingredient by ingredient Bifidobacterium Longum Bifidobacterium Bifidum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both Bifidobacterium longum infantis and Bifidobacterium bifidum are generally well tolerated in healthy people, but caution is advised for seriously ill or immune-compromised infants — these probiotics have rarely caused bacterial bloodstream infections in critically ill or preterm infants, especially after antibiotics or surgery. Rare oral side effects include abdominal discomfort, bloating, flatulence, and constipation.

One case of a dry cough was reported. Because safety data are limited, check with your child's doctor before use.

For breastfeeding, limited data exist for Bifidobacterium longum infantis, so talk with your doctor or pharmacist first; for Bifidobacterium bifidum, there isn't enough data on file to know either way — discuss it with your healthcare provider for personalized advice.

Side effects, ingredient by ingredient Bifidobacterium Longum Bifidobacterium Bifidum

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Bifidobacterium Bifidum, Bifidobacterium Longum.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Separate this product from any antibiotic medications (Moderate interaction) — antibiotics can kill the live bacteria in the probiotic. Ask your child's doctor or pharmacist for the best timing between doses.

We could not check interaction data for Bifidobacterium animalis lactis and Lactobacillus reuteri, so use the search tool on this page to verify your child's exact medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This probiotic blend may help with IBS and respiratory infections (based on one ingredient), but evidence for other uses is not yet established. The main thing to watch is separating doses from any antibiotics your infant is taking — taking them at the same time can reduce how well the probiotics work.

Since rare serious infections have occurred in critically ill or premature infants, talk with your pediatrician before starting, especially if your child is in a hospital setting or has a weakened immune system.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 21, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic Infants Liquid Probiotic Unflavored, straight from the product label.

Brand Mary Ruth's
Net contents 1 Fluid Ounce(s); 30 Milliliter(s)
Market status On market
Date entered into DSLD Jul 21, 2022
DSLD ID 274593
Product type Non-nutrient/non-botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Organic, Infants/Baby (0 - 1 Year), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic Infants Liquid Probiotic Unflavored by Mary Ruth's, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Infants
Minimum serving Sizes:
0.05 mL
Maximum serving Sizes:
0.24 mL
Servings per container
125
IngredientAmount% DV
Proprietary Probiotic Blend250 mg--
Bifidobacterium longum infantis0 NP--
Bifidobacterium bifidum0 NP--
Bifidobacterium animalis lactis0 NP--
Lactobacillus reuteri0 NP--

Other ingredients: Water, Purified, Alfalfa

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: This product was formulated for infants (6-12 months). Once daily, dispense drops directly into baby's mouth, or add to bottle. Please avoid direct dropper contact to infant's mouth in order to prevent product contamination. Start dosage with one drop daily, slowly increasing the dose over several weeks. Dosage for infants not to exceed 5 drops daily.

Precautions

Check with your infant's physician, pediatrician or healthcare professional before beginning any new wellness supplement to make certain the supplement is suitable for your infant's health.

Storage

Store in a cool, dry place. To ensure freshness, we recommend refrigeration after opening.

General Statements

Contact us We love to hear from our customers. Questions? Feedback? Please feel free to call or email us! [email protected] (310) 955-1353

Formulation

USDA Organic

Vegan

Water based

Non GMO Gluten free

All ingredients are vegan and non-GMO

All ingredients are vegan and non-GMO

Seals/Symbols

USDA Organic

CCOF Certified Organic

Formula

4 strains

For infants 6-12 months

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Organic Infants Liquid Probiotic Unflavored by Mary Ruth's label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Organic Infants Liquid Probiotic Unflavored label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Organic Infants Liquid Probiotic Unflavored by Mary Ruth's

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.05 mL Dosage formLiquid Servings per container125 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Probiotic Blend

250 mg per serving

Other (inactive) ingredients: Water, Purified, Alfalfa. These complete the product’s ingredient list but are not active constituents.

Interaction report

Organic Infants Liquid Probiotic Unflavored by Mary Ruth's Drug Interactions

Want to check YOUR meds against Organic Infants Liquid Probiotic Unflavored?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Bifidobacterium longum infantis 182
Bifidobacterium bifidum 182

Individual Drug Interactions

The ingredients in Organic Infants Liquid Probiotic Unflavored interact with 182 drugs. Click any drug to see the details.

2 of the 4 ingredients in Organic Infants Liquid Probiotic Unflavored interact with drugs. Each result below shows which ingredient is responsible. Bifidobacterium longum infantis Bifidobacterium bifidum

Each ingredient & the kinds of drugs it affects

For each ingredient in Organic Infants Liquid Probiotic Unflavored with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Bifidobacterium longum infantis1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B. longum.
Since B. longum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. longum preparations by at least 2 hours.

Likelihood Probable Evidence D
Bifidobacterium longum infantis full monograph & interactions

Bifidobacterium bifidum1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium. bifidum with antibiotic drugs might decrease the effectiveness of B. bifidum.
Since B. bifidum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. bifidum preparations by at least 2 hours.

Likelihood Probable Evidence D
Bifidobacterium bifidum full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Organic Infants Liquid Probiotic Unflavored, from the product label.

Mary Ruth's

Name
MRO MaryRuth, LLC
City
Los Angeles
State
CA
ZipCode
90035
Phone Number
(310) 955-1353
Web Address
www.maryruthorganics.com
Pharmacist Counseling Corner

Organic Infants Liquid Probiotic Unflavored by Mary Ruth's: Common Questions

Does Organic Infants Liquid Probiotic Unflavored by Mary Ruth's interact with any medications?
Yes. Based on its ingredients, Organic Infants Liquid Probiotic Unflavored has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Organic Infants Liquid Probiotic Unflavored contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I give this to my infant if they're on antibiotics?
Not at the same time. Antibiotics will kill the live organisms in this probiotic, making it less effective. Separate the doses by several hours — your child's pediatrician or pharmacist can advise you on the best timing for your situation.
Is this safe for newborns or premature infants?
Generally well tolerated, but very premature or critically ill infants need caution. Rare cases of serious bloodstream infections from these probiotics have occurred in that group. Talk with your pediatrician first, especially if your infant is hospitalized or has a weakened immune system.
What are the side effects?
Most infants tolerate it well. Rare side effects include belly discomfort, bloating, flatulence, and constipation. One case of a dry cough was reported. If you notice any of these, let your pediatrician know.
Does this actually work for anything?
One ingredient, Bifidobacterium bifidum, is possibly effective for irritable bowel syndrome and respiratory tract infections. For other uses like eczema, allergies, or anxiety, the evidence isn't established enough yet to say whether it works.
Is it safe while breastfeeding?
There isn't enough safety data on file to know either way for one ingredient, and limited data for another. Talk with your doctor or pharmacist about whether it's right for your situation while breastfeeding.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic Infants Liquid Probiotic Unflavored is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic Infants Liquid Probiotic Unflavored label
Go deeper

The Full Monographs Behind Organic Infants Liquid Probiotic Unflavored’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bifidobacterium Longum

Interacts with 182 drugs

Bifidobacterium longum is a 'friendly' bacterium found naturally in the human gut and used as a probiotic. It is generally well tolerated and is most studied for digestive issues, though evi...

Read the full Bifidobacterium Longum monograph → Herb & supplement monograph

Bifidobacterium Bifidum

Interacts with 182 drugs

Bifidobacterium bifidum is a 'friendly' bacteria (probiotic) that naturally lives in the human gut and is taken to support digestion and gut balance. Some evidence suggests probiotics may he...

Read the full Bifidobacterium Bifidum monograph →
Sources

Sources & How We Checked

Organic Infants Liquid Probiotic Unflavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 28 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bifidobacterium Longum 21 references
  1. Ha GY, Yang CH, Kim H, Chong Y. Case of sepsis caused by Bifidobacterium longum. J Clin Microbiol 1999;37:1227-8.
  2. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  3. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  4. Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130(6):1355-60. PubMed
  5. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  6. Pellonperä O, Vahlberg T, Mokkala K, et al. Weight gain and body composition during pregnancy: a randomised pilot trial with probiotics and/or fish oil. Br J Nutr. 2020 Nov 4:1-11. PubMed
  7. Pellonperä O, Mokkala K, Houttu N, et al. Efficacy of fish oil and/or probiotic intervention on the incidence of gestational diabetes mellitus in an at-risk group of overweight and obese women: A randomized, placebo-controlled, double-blind clinical trial PubMed
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
  10. Enomoto T, Sowa M, Nishimori K, et al. Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergol Int 2014;63(4):575-85. PubMed
  11. US Food and Drug Administration (FDA). Dear Healthcare Provider Letter: Warning Regarding Use of Probiotics in Preterm Infants. September 2023. Available at: https://www.fda.gov/media/172606/download?attachment. Accessed November 1, 2023.
  12. Pillai A, Tan J, Paquette V, Panczuk J. Does probiotic bacteremia in premature infants impact clinically relevant outcomes? A case report and updated review of literature. Clin Nutr ESPEN. 2020;39:255-259. PubMed
  13. Sabaté JM, Iglicki F. Effect of Bifidobacterium longum 35624 on disease severity and quality of life in patients with irritable bowel syndrome. World J Gastroenterol 2022;28(7):732-744.
  14. Malaguarnera M, Greco F, Barone G, Gargante MP, Malaguarnera M, Toscano MA. Bifidobacterium longum with fructo-oligosaccharide (FOS) treatment in minimal hepatic encephalopathy: a randomized, double-blind, placebo-controlled study. Dig Dis Sci 2007;52(11) PubMed
  15. Zbinden A, Zbinden R, Berger C, Arlettaz R. Case series of Bifidobacterium longum bacteremia in three preterm infants on probiotic therapy. Neonatology 2015;107(1):56-9.
  16. Tamaki H, Nakase H, Inoue S, et al. Efficacy of probiotic treatment with Bifidobacterium longum 536 for induction of remission in active ulcerative colitis: A randomized, double-blinded, placebo-controlled multicenter trial. Dig Endosc 2016;28(1):67-74.
  17. Bertelli C, Pillonel T, Torregrossa A, et al. Bifidobacterium longum bacteremia in preterm infants receiving probiotics. Clin Infect Dis 2015;60(6):924-7. PubMed
  18. Esaiassen E, Cavanagh P, Hjerde E, Simonsen GS, Støen R, Klingenberg C. Bifidobacterium longum subspecies infantis bacteremia in 3 extremely preterm infants receiving probiotics. Emerg Infect Dis 2016;22(9):1664-6.
  19. Tena D, Losa C, Medina MJ, Sáez-Nieto JA. Peritonitis caused by Bifidobacterium longum: case report and literature review. Anaerobe 2014;27:27-30. PubMed
  20. Sangkanjanavanich S, Pradubpongsa P, Mitthamsiri W, Sangasapaviliya A, Boonpiyathad T. Bifidobacterium infantis 35624 efficacy in patients with uncontrolled asthma: A randomized placebo-controlled trial. Ann Allergy Asthma Immunol 2022;129(6):790-792. PubMed
  21. Wilson HL, Ong CW. Bifidobacterium longum vertebrodiscitis in a patient with cirrhosis and prostate cancer. Anaerobe 2017;47:47-50. PubMed

See these in context on the Bifidobacterium Longum monograph →

Bifidobacterium Bifidum 7 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  3. Rerksuppaphol S, Rerksuppaphol L. Randomized controlled trial of probiotics to reduce common cold in schoolchildren. Pediatr Int. 2012;54(5):682-7. PubMed
  4. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  5. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  6. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  7. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed

See these in context on the Bifidobacterium Bifidum monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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