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Dietary supplement

Organic Lion's Mane Mushroom Liquid Drops Ingredients & Drug Interactions

by dr.bo HERBALS

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Organic Lion's Mane Mushroom Liquid Drops is a dietary supplement by dr.bo HERBALS with 1 active ingredient. Its ingredients are commonly taken for memory and cognitive support, nerve health, mood and anxiety.Based on those ingredients, 327 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lion's Mane Mushroom. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Organic Lion's Mane Mushroom Liquid Drops by dr.bo HERBALS

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: lion's mane mushroom, a medicinal fungus used traditionally to support brain health and immunity. The liquid formula also includes glycerin and purified water as inactive ingredients to deliver the mushroom extract.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Lion's Mane Mushroom's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Memory and cognitive support.
  • We looked for evidence on: Alzheimer disease, Cognitive function, Cognitive impairment, Dementia, Memory, Parkinson disease — and 4 related terms.
  • The closest evidence on file: Lion's Mane Mushroom is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease (Natural Medicines).
  • Also on file: Lion's Mane Mushroom is rated "Insufficient Reliable Evidence To Rate" for Cognitive function, Cognitive impairment, Dementia, Memory, and more.

The evidence we hold rates lion's mane mushroom as having insufficient reliable evidence for Alzheimer disease, anxiety, athletic performance, cancer, cognitive function, and cognitive impairment. In plain terms, we don't yet have solid clinical data showing it works for these uses.

If you're considering it for one of these reasons, talk with your pharmacist about what the current research actually supports.

The evidence, ingredient by ingredient Lion's Mane Mushroom

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 0 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lion's mane mushroom is generally well tolerated when taken by mouth. The most common side effects reported are gastrointestinal discomfort, nausea, and skin rash, though these occur in a small number of people.

Long-term supplement safety hasn't been thoroughly studied, so caution is warranted with extended use. There isn't enough safety data to use this product during pregnancy or while breastfeeding — talk with your doctor or pharmacist before use if either applies to you.

Side effects, ingredient by ingredient Lion's Mane Mushroom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lion's Mane Mushroom.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 327 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications before starting, especially blood thinners and antiplatelet drugs (increased bleeding risk), diabetes medications (additive blood sugar-lowering effect), and immunosuppressant drugs (potential interference with immunity suppression). Use the medication search tool on this page to look up your exact prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.

Lion's mane mushroom may be worth considering if you're interested in cognitive or immune support, but the evidence for specific conditions isn't established yet. If you take blood thinners, diabetes medications, or immunosuppressants, you'll need to check with your pharmacist first.

Pregnancy and breastfeeding are not recommended without medical guidance.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic Lion's Mane Mushroom Liquid Drops, straight from the product label.

Brand dr.bo HERBALS
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Jun 25, 2025
DSLD ID 328685
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Organic, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic Lion's Mane Mushroom Liquid Drops by dr.bo HERBALS, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.5 mL
Maximum serving Sizes:
0.5 mL
Servings per container
60
IngredientAmount% DV
Lion's Mane Mushroom0.5 mL--

Other ingredients: Glycerin, Water, Purified

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: Shake gently before use. Take up to 15 drops (0.5 mL) 1 to 3 times a day, or as directed by a healthcare professional. Can be taken directly by mouth or added to water.

Precautions

Please avoid direct dropper contact to the skin or mouth in order to prevent product contamination and damage to the dropper.

Keep out of the reach of children.

Do not use if safety seal is damaged or missing. Do not exceed recommended dose. Discontinue use if negative reaction occurs.

Consult a physician before using this or any dietary supplement, especially if pregnant, nursing, taking medication, or have a medical condition.

Storage

No refrigeration necessary

Store in a cool, dry place.

General Statements

1 pump = approximately 22 drops

Facebook Instagram Follow us: @DRBO Nutrition

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

USDA Organic

Formulation

USDA Organic Certified organic by Organic Certifiers, Ventura, CA

All ingredients are vegan and non-GMO

All ingredients are vegan and non-GMO

FDA Statement of Identity

Dietary Supplement

See for yourself

Organic Lion's Mane Mushroom Liquid Drops by dr.bo HERBALS label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Organic Lion's Mane Mushroom Liquid Drops by dr.bo HERBALS

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.5 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.

Lion's Mane Mushroom

Interacts with
327 drugs
0.5 mL per serving Form: Hericium erinaceus

Lion's mane is an edible mushroom that is popular as a 'nootropic' for memory, focus, and nerve health, but solid human evidence is still limited and...

Lion's Mane Mushroom monograph & interactions

Other (inactive) ingredients: Glycerin, Water, Purified. These complete the product’s ingredient list but are not active constituents.

Interaction report

Organic Lion's Mane Mushroom Liquid Drops by dr.bo HERBALS Drug Interactions

Want to check YOUR meds against Organic Lion's Mane Mushroom Liquid Drops?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
327Drugs
327 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Organic Lion's Mane Mushroom Liquid Drops with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lion's Mane Mushroom3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
In vitro research suggests that lion's mane mushroom extracts can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Animal research suggests that an aqueous extract of lion's mane mushroom can reduce serum glucose and increase serum insulin.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
In animal and in vitro research, lion's mane mushroom polysaccharides stimulate the immune system.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Organic Lion's Mane Mushroom Liquid Drops, from the product label.

dr.bo HERBALS

See all dr.bo HERBALS products
Name
DR.BO
City
Sherman Oaks
State
CA
ZipCode
91403
Web Address
drbo.com
Pharmacist Counseling Corner

Organic Lion's Mane Mushroom Liquid Drops by dr.bo HERBALS: Common Questions

Does Organic Lion's Mane Mushroom Liquid Drops by dr.bo HERBALS interact with any medications?
Yes. Based on its ingredients, Organic Lion's Mane Mushroom Liquid Drops has a known interaction with 327 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Organic Lion's Mane Mushroom Liquid Drops contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's lion's mane mushroom supposed to do?
It's traditionally used to support brain health and immunity. However, we don't have solid clinical evidence that it works for Alzheimer disease, cognitive function, anxiety, or other specific conditions listed in our data.
Can I take this if I'm on a blood thinner like warfarin?
You need to check with your pharmacist first. Lion's mane may increase bleeding risk when combined with blood thinners and antiplatelet drugs. Run your specific medication through the checker on this page.
What are the side effects?
Most people tolerate it well. Some experience gastrointestinal discomfort, nausea, or a skin rash, though these are uncommon. Long-term safety data is limited.
Is it safe to take while I'm pregnant?
There isn't enough safety data to recommend it during pregnancy. Talk with your doctor or pharmacist before use if you're pregnant or planning to become pregnant.
Can I use this while breastfeeding?
There isn't enough safety data during breastfeeding. Speak with your doctor or pharmacist before starting if you're nursing.
Is this product just the mushroom, or does it have other stuff in it?
It's lion's mane mushroom extract plus glycerin and purified water as inactive ingredients to create the liquid form.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic Lion's Mane Mushroom Liquid Drops is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic Lion's Mane Mushroom Liquid Drops label
Go deeper

The Full Monographs Behind Organic Lion's Mane Mushroom Liquid Drops’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Organic Lion's Mane Mushroom Liquid Drops's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lion's Mane Mushroom 6 references
  1. Product information for <em>Niaspan</em>. Abbott Laboratories. North Chicago, IL 60064. April 2015.
  2. Liang B, Guo Z, Xie F, Zhao A. Antihyperglycemic and antihyperlipidemic activities of aqueous extract of Hericium erinaceus in experimental diabetic rats. BMC Complement Altern Med. 2013;13:253. PubMed
  3. Mori K, Inatomi S, Ouchi K, Azumi Y, Tuchida T. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. Phytother Res. 2009;23(3):367-72.
  4. Mori K, Kikuchi H, Obara Y, et al. Inhibitory effect of hericenone B from Hericium erinaceus on collagen-induced platelet aggregation. Phytomedicine. 2010;17(14):1082-5. PubMed
  5. Li IC, Chang HH, Lin CH, et al. Prevention of early Alzheimer's disease by erinacine A-enriched Hericium erinaceus mycelia pilot double-blind placebo-controlled study. Front Aging Neurosci 2020 Jun 3;12:155. doi: 10.3389/fnagi.2020.00155. PubMed
  6. Tian B, Liu R, Xu T, et al. Modulating effects of Hericium erinaceus polysaccharides on the immune response by regulating gut microbiota in cyclophosphamide-treated mice. J Sci Food Agric 2023;103(6):3050-3064.

See these in context on the Lion's Mane Mushroom monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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