Interactions on record — worth a quick check against your medications. Based on 1 of 11 ingredients. Check your meds →
Dietary supplement

Organic Sprouted Flax Seeds Ingredients & Drug Interactions

by Higher Nature

Organic Sprouted Flax Seeds label
See full label image
Other (e.g. Tea Bag) Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Organic Sprouted Flax Seeds against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Organic Sprouted Flax Seeds is a dietary supplement by Higher Nature with 11 active ingredients. Its ingredients are commonly taken for constipation and digestive health, high cholesterol, heart health.Based on those ingredients, 597 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lignans. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Organic Sprouted Flax Seeds by Higher Nature

Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Sprouted Flax Seeds by Higher Nature — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Organic Sprouted Flax Seeds by Higher Nature

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 8 of its 8 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 8 ingredients, including the active lignans from flaxseed—plant compounds with potential health effects. You're also getting linoleic acid, alpha-linolenic acid (an omega-3 fat), fiber, and various other fatty acids that naturally occur in flax seeds.

The inactive ingredient is the organically grown golden sprouted flax itself.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Fibre, omega fatty acids, and lignans support.
  • We looked for evidence on: Constipation, Hypercholesterolemia, Cardiovascular disease (CVD), Menopausal symptoms, Diabetes, Impaired glucose tolerance (prediabetes) — and 4 related terms.
  • The strongest evidence on file: Flaxseed is rated "Possibly Effective" for Constipation (Natural Medicines).
  • Also on file: Flaxseed is rated "Possibly Effective" for Diabetes, Hypercholesterolemia, Hypertension, Obesity.
  • Also on file: Flaxseed is rated "Insufficient Reliable Evidence To Rate" for Cardiovascular disease (CVD), Menopausal symptoms.

The lignans in flaxseed have some evidence behind them. The data we hold shows flaxseed is possibly effective for high cholesterol, type 2 diabetes, breast pain (mastalgia), and high blood pressure.

It's also possibly effective for constipation. Keep in mind that these are "possibly effective" ratings—the evidence exists but isn't rock-solid, so results vary from person to person.

The evidence, ingredient by ingredient Flaxseed

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Flaxseed is generally well tolerated when eaten as food, though you'll want to drink plenty of water and start with small amounts to minimize bloating and gas. The most common side effects are digestive: bloating, diarrhea, and abdominal discomfort, especially at higher doses.

Doses over 45 grams per day may not be tolerated because of increased bowel movements and diarrhea risk. Severe allergic reactions are rare but possible.

For supplement doses (as opposed to food amounts), there's concern about hormone-like effects, so get your doctor's approval first. There isn't enough reliable safety data on flaxseed supplements during breastfeeding, so use caution and talk with your healthcare provider.

Side effects, ingredient by ingredient Flaxseed

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Flaxseed.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 597 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, double-check if you're on blood thinners or antiplatelet drugs (like warfarin or aspirin in prescription doses)—flaxseed may increase bleeding risk. Also flag it with your pharmacist if you take blood pressure medications, antibiotics, estrogen-based birth control, or diabetes drugs, since flaxseed could change how these work.

Altogether, these interactions span 594 individual medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you're managing high cholesterol, blood sugar, or blood pressure, and you're not on blood thinners, birth control, or diabetes medications, flaxseed is worth a conversation with your pharmacist. If you take any of those drugs—or any blood pressure or antibiotic medication—check your specific drugs on this page before you start.

Start low with small amounts to see how your digestive system handles it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic Sprouted Flax Seeds, straight from the product label.

Brand Higher Nature
Barcode (UPC) 5031013104954
Net contents 250 Gram(s)
Market status On market
Date entered into DSLD Jun 24, 2020
DSLD ID 228198
Product type Other Combinations
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses Nutrient, All Other
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic Sprouted Flax Seeds by Higher Nature, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
15 Gram(s)
Maximum serving Sizes:
15 Gram(s)
UPC/BARCODE
5031013104954
IngredientAmount% DV
Sugar0.2 Gram(s), 1.6 Gram(s)0.3%, 1.8%
Salt0.00169 Gram(s), 0.1125 Gram(s)0.3%, 1.9%
Carbohydrates5.1 Gram(s), 34 Gram(s)2%, 13.1%
Protein3 Gram(s), 20.2 Gram(s)6.1%, 40.4%
Energy0 NP9%
Linoleic Acid0.9 Gram(s), 6.2 Gram(s)--
Alpha-Linolenic Acid3.5 Gram(s), 23.3 Gram(s)--
Fiber3.9 Gram(s), 26.2 Gram(s)--
Lignans0.2 Gram(s), 1.3 Gram(s)--
Saturates0.6 Gram(s), 3.7 Gram(s)2.8%, 18.5%
Total Fat6 Gram(s), 39.7 Gram(s)8.5%, 56.7%
Polyunsaturates3.9 Gram(s), 25.9 Gram(s)--
Monosaturates1.2 Gram(s), 8.2 Gram(s)--

Other ingredients: organically grown golden sprouted Flax

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

RI = Reference Intake of an average adult (8400kJ/ 2000kcal) This pack provides more than 16 x 15 gram portions.

This product is not tested on animals.

Omega Excellence

This superior PET jar is 100% stable & non toxic.

Contents may settle during transit.

Jar 1 PET Lid 5 PP

Formulation

Does Not Contain: soya, wheat, gluten, maize, corn, yeast, lactose, dairy products, artificial preservatives, colours or flavourings. No added sugar, salt or starch.

Suitable for vegetarians and vegans.

Vegan

High in fibre, protein and omega 3.

The process of sprouted helps improve enzyme activity and may increase the content of macro and micro nutrients within the food.

Organic Food Federation Certified Organic GB-ORG-04 Canadian Agriculture

Formula

fibre, lignans & omegas 3, 6 & 9

Ground seeds

Naturally sweet Organic Sprouted Flax Seeds are a good source of lignans, fibre, protein, omega 3 and magnesium.

Suggested/Recommended/Usage/Directions

Sprinkle over salads or breakfast cereal, blend into drinks and smoothies or stir into yoghurt. Tastes great straight from the spoon. Not suitable for cooking or baking.

Seals/Symbols

Organic Food Federation Certified Organic GB-ORG-04 Canadian Agriculture

Storage

Store in a cool, dark place. Refrigerate after opening and is best consumed within 3 months.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Organic Sprouted Flax Seeds by Higher Nature label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Organic Sprouted Flax Seeds label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Organic Sprouted Flax Seeds by Higher Nature

These are the 11 active ingredients this product is made of. Select any to open its full monograph.

Serving size15 Gram(s) Dosage formOther (e.g. Tea Bag) Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Salt

0.00169 Gram(s) per serving

Carbohydrates

5.1 Gram(s) per serving
  • › Sugar

Protein

3 Gram(s) per serving

Energy

0 NP per serving

Linoleic Acid

0.9 Gram(s) per serving

Alpha-Linolenic Acid

3.5 Gram(s) per serving

Fiber

3.9 Gram(s) per serving

Lignans

Interacts with
597 drugs
0.2 Gram(s) per serving

Flaxseed is a nutritious food rich in fiber, omega-3 fats (ALA), and plant compounds called lignans. It is most reliably helpful for constipation and...

Lignans monograph & interactions

Saturates

0.6 Gram(s) per serving

Polyunsaturates

3.9 Gram(s) per serving

Monosaturates

1.2 Gram(s) per serving

Other (inactive) ingredients: Organically grown golden sprouted Flax. These complete the product’s ingredient list but are not active constituents.

Interaction report

Organic Sprouted Flax Seeds by Higher Nature Drug Interactions

Want to check YOUR meds against Organic Sprouted Flax Seeds?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
597Drugs
597 Moderate

Ingredients driving the most interactions

Lignans 597

Individual Drug Interactions

The ingredients in Organic Sprouted Flax Seeds interact with 597 drugs. Click any drug to see the details.

1 of the 11 ingredients in Organic Sprouted Flax Seeds interact with drugs. Each result below shows which ingredient is responsible. Lignans

Each ingredient & the kinds of drugs it affects

For each ingredient in Organic Sprouted Flax Seeds with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lignans5 drug types · 597 drugs

Antibiotic Drugs

Theoretically, antibiotics might interfere with the metabolism of flaxseed constituents, which could potentially alter the effects of flaxseed.
Some potential benefits of flaxseed are thought to be due to its lignan content. Secoisolariciresinol diglucoside (SDG), a major lignan precursor, is found in high concentrations in flaxseed. SDG is converted by bacteria in the colon to the lignans enterolactone and enterodiol. Antibiotics alter the flora of the colon, which could theoretically alter the metabolism of flaxseed.

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Some clinical evidence suggests that the oil contained in flaxseed can decrease platelet aggregation.

Likelihood Possible Evidence B
Antidiabetes Drugs

Theoretically, flaxseed might have additive effects when used with antidiabetes drugs and increase the risk for hypoglycemia.
Some clinical research suggests that flaxseed can lower blood glucose levels.

Likelihood Probable Evidence B
Antihypertensive Drugs

Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Clinical research shows that daily flaxseed consumption, especially for longer than 12 weeks, modestly reduces blood pressure.

Likelihood Possible Evidence D
Estrogens

Theoretically, taking flaxseed might decrease the effects of estrogens.
Flaxseed contains lignans with mild estrogenic and possible antiestrogenic effects. The lignans seem to compete with circulating endogenous estrogen and might reduce estrogen binding to estrogen receptors, resulting in an anti-estrogen effect. It is unclear if this effect transfers to exogenously administered estrogens.

Likelihood Possible Evidence D
Lignans full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Organic Sprouted Flax Seeds, from the product label.

Higher Nature

See all Higher Nature products
Name
Higher Nature
City
Burwash Common
State
East Sussex
ZipCode
TN19 7LX
Web Address
www.highernature.com
Pharmacist Counseling Corner

Organic Sprouted Flax Seeds by Higher Nature: Common Questions

Does Organic Sprouted Flax Seeds by Higher Nature interact with any medications?
Yes. Based on its ingredients, Organic Sprouted Flax Seeds has a known interaction with 597 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Organic Sprouted Flax Seeds contains 11 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this hurt my birth control?
Flaxseed's lignans may reduce how well estrogen-based birth control works, which is a Moderate concern. Talk to your doctor or pharmacist before adding flaxseed if you're on hormonal contraception—they can help you weigh the risk.
What's the most common side effect?
Digestive upset—bloating, diarrhea, and gas are most likely, especially when you start or take higher doses. Drinking plenty of water and beginning with small amounts helps. If you go over 45 grams a day, digestive problems are more likely.
Is it safe during pregnancy?
The data rates flaxseed as possibly unsafe in pregnancy because of potential hormone-like effects at supplement doses. Talk with your doctor before using it if you're pregnant or trying to become pregnant.
Does flaxseed actually lower cholesterol?
The evidence shows flaxseed is possibly effective for high cholesterol, which means there's some clinical research backing it, but results aren't guaranteed and vary between people.
Can I use this if I'm on antibiotics?
There's a Moderate interaction: antibiotics might interfere with how your body breaks down flaxseed's active compounds. Check with your pharmacist before combining them, especially if you're on a longer course.
What's sprouted flax, and does it change anything?
Sprouted flax is flaxseed that's been allowed to sprout—it's the same plant source and contains the same lignans and active compounds that produce the interactions and effects listed here.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic Sprouted Flax Seeds is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic Sprouted Flax Seeds label
Go deeper

The Full Monographs Behind Organic Sprouted Flax Seeds’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Flaxseed

Interacts with 597 drugs

Flaxseed is a nutritious food rich in fiber, omega-3 fats (ALA), and plant compounds called lignans. It is most reliably helpful for constipation and may modestly lower cholesterol, but evid...

Read the full Flaxseed monograph →
Sources

Sources & How We Checked

Organic Sprouted Flax Seeds's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 37 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Flaxseed 37 references
  1. Kolonel LN, Nomura AM, Cooney RV. Dietary fat and prostate cancer: current status. J Natl Cancer Inst 1999;91:414-28. PubMed
  2. Ramon JM, Bou R, Romea S, et al. Dietary fat intake and prostate cancer risk: a case-control study in Spain. Cancer Causes Control 2000;11:679-85. PubMed
  3. Thompson LU, Rickard SE, Cheung F, et al. Variability in anticancer lignan levels in flaxseed. Nutr Cancer 1997;27:26-30. PubMed
  4. Nordstrom DC, Honkanen VE, Nasu Y, et al. Alpha-linolenic acid in the treatment of rheumatoid arthritis. A double-blind, placebo-controlled and randomized study: flaxseed vs. safflower seed. Rheumatol Int 1995;14:231-4. PubMed
  5. Cunnane SC, Ganguli S, Menard C, et al. High alpha-linolenic acid flaxseed (Linum usitatissimum): some nutritional properties in humans. Br J Nutr 1993;69:443-53.
  6. Clark WF, Parbtani A, Huff MW, et al. Flaxseed: a potential treatment for lupus nephritis. Kidney Int 1995;48:475-80. PubMed
  7. Cunnane SC, Hamadeh MJ, Liede AC, et al. Nutritional attributes of traditional flaxseed in healthy young adults. Am J Clin Nutr 1995;61:62-8. PubMed
  8. De Stefani E, Deneo-Pellegrini H, Boffetta P, et al. Alpha-linolenic acid and risk of prostate cancer: a case-control study in Uruguay. Cancer Epidemiol Biomarkers Prev 2000;9:335-8.
  9. Giovannucci E, Rimm EB, Colditz GA, et al. A prospective study of dietary fat and risk of prostate cancer. J Natl Cancer Inst 1993;85:1571-9. PubMed
  10. Clark WF, Kortas C, Heidenheim P, et al. Flaxseed in lupus nephritis: a two-year nonplacebo-controlled crossover study. J Am Coll Nutr 2001;20:143-8. PubMed
  11. Serraino M, Thompson LU. The effect of flaxseed supplementation on early risk markers for mammary carcinogenesis. Cancer Lett 1991;60:135-42. PubMed
  12. Rickard SE, Yuan YV, Thompson LU. Plasma insulin-like growth factor I levels in rats are reduced by dietary supplementation of flaxseed or its lignan secoisolariciresinol diglycoside. Cancer Lett 2000;161:47-55. PubMed
  13. Mousavi Y, Adlercreutz H. Enterolactone and estradiol inhibit each other's proliferative effect on MCF-7 breast cancer cells in culture. J Steroid Biochem Mol Biol 1992;41:615-9.. PubMed
  14. Adlercreutz H, Fotsis T, Bannwart C, et al. Determination of urinary lignans and phytoestrogen metabolites, potential antiestrogens and anticarcinogens, in urine of women on various habitual diets. J Steroid Biochem 1986;25:791-7.. PubMed
  15. Rose DP. Dietary fiber and breast cancer. Nutr Cancer 1990;13:1-8.. PubMed
  16. Lemay A, Dodin S, Kadri N, et al. Flaxseed dietary supplement versus hormone replacement therapy in hypercholesterolemic menopausal women. Obstet Gynecol 2002;100:495-504.. DOI
  17. Brooks JD, Ward WE, Lewis JE, et al. Supplementation with flaxseed alters estrogen metabolism in postmenopausal women to a greater extent than does supplementation with an equal amount of soy. Am J Clin Nutr 2004;79:318-25.. PubMed
  18. Laaksonen DE, Laukkanen JA, Niskanen L, et al. Serum linoleic and total polyunsaturated fatty acids in relation to prostate and other cancers: a population-based cohort study. Int J Cancer 2004;111:444-50.. PubMed
  19. Dodin S, Lemay A, Jacques H, et al. The effects of flaxseed dietary supplement on lipid profile, bone mineral density, and symptoms in menopausal women: a randomized, double-blind, wheat germ placebo-controlled clinical trial. J Clin Endocrinol Metab 2005 PubMed
  20. Brouwer IA, Katan MB, Zock PL. Dietary alpha-linolenic acid is associated with reduced risk of fatal coronary heart disease, but increased prostate cancer risk: a meta-analysis. J Nutr 2004;134:919-22.
  21. Demark-Wahnefried W, Polascik TJ, George SL, et al. Flaxseed supplementation (not dietary fat restriction) reduces prostate cancer proliferation rates in men presurgery. Cancer Epidemiol Biomarkers Prev 2008;17:3577-87. PubMed
  22. Thompson LU, Chen JM, Li T, et al. Dietary flaxseed alters tumor biological markers in postmenopausal breast cancer. Clin Cancer Res 2005;11:3828-35. PubMed
  23. Mani UV, Mani I, Biswas M, Kumar SN. An open-label study on the effect of flax seed powder (Linum usitatissimum) supplementation in the management of diabetes mellitus. J Diet Suppl 2011;8:257-65.
  24. Rhee Y, Brunt A. Flaxseed supplementation improved insulin resistance in obese glucose intolerant people: a randomized crossover design. Nutr J 2011;10:44. PubMed
  25. Cornish SM, Chilibeck PD, Paus-Jennsen L, et al. A randomized controlled trial of the effects of flaxseed lignan complex on metabolic syndrome composite score and bone mineral in older adults. Appl Physiol Nutr Metab 2009;34:89-98. PubMed
  26. Cockerell KM, Watkins AS, Reeves LB, et al. Effects of linseeds on the symptoms of irritable bowel syndrome: a pilot randomised controlled trial. J Hum Nutr Diet 2012;25:435-43. PubMed
  27. Colli MC, Bracht A, Soares AA, et al. Evaluation of the efficacy of flaxseed meal and flaxseed extract in reducing menopausal symptoms. J Med Food 2012;15:840-5. PubMed
  28. Allman, M. A., Pena, M. M., and Pang, D. Supplementation with flaxseed oil versus sunflowerseed oil in healthy young men consuming a low fat diet: effects on platelet composition and function. Eur.J Clin.Nutr. 1995;49(3):169-178.
  29. Simbalista RL, Sauerbronn AV, Aldrighi JM, Areas JA. Consumption of a flaxseed-rich food is not more effective than a placebo in alleviating the climacteric symptoms of postmenopausal women. J Nutr 2010;140:293-7. PubMed
  30. Patade A, Devareddy L, Lucas EA, et al. Flaxseed reduces total and LDL cholesterol concentrations in Native American postmenopausal women. J Womens Health (Larchmt) 2008;17:355-66. PubMed
  31. Rodriguez-Leyva D, Weighell W, Edel AL, LaVallee R, Dibrov E, Pinneker R, Maddaford TG, Ramjiawan B, Aliani M, Guzman R, Pierce GN. Potent antihypertensive action of dietary flaxseed in hypertensive patients. Hypertension. 2013 Dec;62(6):1081-9. PubMed
  32. Bloedon LT, Balikai S, Chittams J, et al. Flaxseed and cardiovascular risk factors: results from a double blind, randomized, controlled clinical trial. J Am Coll Nutr 2008;27:65-74. PubMed
  33. Ursoniu S, Sahebkar A, Andrica F, Serban C, Banach M; Lipid and Blood Pressure Meta-analysis Collaboration Group. Effects of flaxseed supplements on blood pressure: a systematic review and meta-analysis of controlled clinical trial. Clin Nutr. 2016 Jun;3 PubMed
  34. Mohammadi-Sartang M, Sohrabi Z, Barati-Bodaji R, Raeisi-Dehkordi H, Mazloom Z. Flaxseed supplementation on glucose control and insulin sensitivity: a systematic review and meta-analysis of 25 randomized, placebo-controlled trials. Nutr Rev. 2018 Feb 1;76( PubMed
  35. Haidari F, Banaei-Jahromi N, Zakerkish M, Ahmadi K. The effects of flaxseed supplementation on metabolic status in women with polycystic ovary syndrome: a randomized open-labeled controlled clinical trial. Nutr J. 2020;19(1):8. PubMed
  36. Villarreal-Renteria AI, Herrera-Echauri DD, Rodríguez-Rocha NP, et al. Effect of flaxseed (Linum usitatissimum) supplementation on glycemic control and insulin resistance in prediabetes and type 2 diabetes: A systematic review and meta-analysis of randomi
  37. Li L, Li H, Gao Y, Vafaei S, Zhang X, Yang M. Effect of flaxseed supplementation on blood pressure: a systematic review, and dose-response meta-analysis of randomized clinical trials. Food Funct 2023;14(2):675-690. PubMed

See these in context on the Flaxseed monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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