ParActin 300 mg Ingredients & Drug Interactions
by SuperSmart
What is this page for?
First and foremost: checking ParActin 300 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
ParActin 300 mg is a dietary supplement by SuperSmart with 1 active ingredient. Its ingredients are commonly taken for common cold and flu symptoms, upper respiratory infections, sore throat.Based on those ingredients, 413 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are ParActin Andrographis paniculata leaf extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against ParActin 300 mg by SuperSmart
Ask about any prescription or over-the-counter medication and we check it for interactions with ParActin 300 mg by SuperSmart — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of ParActin 300 mg by SuperSmart
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- No proprietary blends here — you can verify the dose of every single component.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 1 of the 1 matched ingredient can interact with medications — Andrographis.
- The most serious interaction on file is rated Moderate.
- Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs.
- For scale: 413 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
- Pregnancy & breastfeeding safety ratings cover 1 of 1.
- General safety write-ups exist for 1 of 1.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about ParActin 300 mg, straight from the product label.
| Brand | SuperSmart |
|---|---|
| Net contents | 90 Vegetarian Capsule(s) |
| Market status | Off market |
| Date entered into DSLD | Jun 24, 2020 |
| DSLD ID | 222843 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for ParActin 300 mg by SuperSmart, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| ParActin Andrographis paniculata leaf extract | 300 mg | -- |
Other ingredients: Acacia Gum, White Rice Flour
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
ParActin is the registered trademark of HP ingredients.
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Recommended use: Adults. Take 3 capsules a day.
Formula
Each vegetarian capsule contains 100 mg ParActin.
Precautions
Precautions: Do not exceed the recommended daily dose. This product is a nutritional supplement and should not replace a varied, balanced diet.
Keep out of childrens' reach.
As with any nutritional supplement, you should consult a health professional before taking this product if you are pregnant, breastfeeding or have a health problem.
Storage
Store away from direct light, heat and humidity.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
ParActin 300 mg by SuperSmart label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in ParActin 300 mg by SuperSmart
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size3 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
ParActin Andrographis paniculata leaf extract
Interacts with413 drugs
Andrographis is a bitter Asian herb traditionally used for colds, flu, and infections, and some studies suggest it may ease cold symptoms and shorten...
ParActin Andrographis paniculata leaf extract monograph & interactionsOther (inactive) ingredients: Acacia Gum, White Rice Flour. These complete the product’s ingredient list but are not active constituents.
ParActin 300 mg by SuperSmart Drug Interactions
ParActin 300 mg contains a single active ingredient, and it has known interactions with 413 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against ParActin 300 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in ParActin 300 mg interact with 413 drugs. Click any drug to see the details.
1 of the 1 ingredient in ParActin 300 mg interact with drugs. Each result below shows which ingredient is responsible. ParActin Andrographis paniculata leaf extract
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + 6-mercaptopurine interactionAbciximabReoPro
How Abciximab interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractAnticoagulant/antiplatelet Drugs, Immunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Abrocitinib interactionAcebutololRhotral, Sectral
How Acebutolol interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Acetaminophen, Ibuprofen interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Acetazolamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Acetylsalicylic Acid interactionAdalimumabHumira
How Adalimumab interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Adalimumab-fkjp interactionAlefaceptAmevive
How Alefacept interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Alemtuzumab interactionAliskirenTekturna
How Aliskiren interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Aliskiren interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Amiloride, Hydrochlorothiazide interactionAmlodipineNorliqva
How Amlodipine interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with ParActin 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Paractin Andrographis Paniculata Leaf ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Paractin Andrographis Paniculata Leaf Extract + Amlodipine Besylate interactionEach ingredient & the kinds of drugs it affects
For each ingredient in ParActin 300 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
ParActin Andrographis paniculata leaf extract
Anticoagulant/Antiplatelet Drugs
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Animal and laboratory studies suggest that andrographis has antiplatelet effects.
Antihypertensive Drugs
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Animal research suggests that andrographis has hypotensive effects.
Immunosuppressants
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Laboratory research suggests that andrographolide has immunostimulant activity.
Celecoxib (Celebrex)
Theoretically, andrographis extract might increase the maximum concentration and time to peak concentration of celecoxib. The clinical significance of these changes is unclear.
Animal research suggests that andrographis extract taken orally increases the maximum concentration and time to peak concentration of celecoxib but does not appear to impact the area under the curve.
Etoricoxib (Arcoxia)
Theoretically, andrographis might decrease the absorption of etoricoxib, although the clinical significance is unclear.
Animal research shows that andrographis extract, or the constituent andrographolide, taken orally with etoricoxib decreases the bioavailability of etoricoxib. However, this reduced bioavailability is not correlated with a reduction in the anti-inflammatory effects of etoricoxib in arthritic mice models. The clinical significance of this interaction is unclear.
Glipizide (Glucotrol)
Theoretically, andrographis extract might increase the maximum concentration and area under the curve of glipizide; however, opposite effects are seen with the constituent, andrographolide. The clinical significance of this interaction is unclear.
Animal research suggests that andrographis extract taken orally with glipizide in diabetes-induced rats increases the maximum concentration and area under the curve of glipizide. However, the opposite effect is seen with the constituent, andrographolide, in which the maximum concentration and area under the curve are decreased when taken with glipizide.
Brand information
Manufacturer and brand details for ParActin 300 mg, from the product label.
SuperSmart
See all SuperSmart products- Name
- SN Worldwide Unipessoal, Lda
- Street Address
- Avenida Do Infante 66, Edificio Quinta Avenida 1 C
- City
- Funchal
- ZipCode
- 9000-015
ParActin 300 mg by SuperSmart: Common Questions
Does ParActin 300 mg by SuperSmart interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if ParActin 300 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind ParActin 300 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
ParActin 300 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 26 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Andrographis 26 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Thamlikitkul V, Dechatiwongse T, Theerapong S, et al. Efficacy of Andrographis paniculata, Nees for pharyngotonsillitis in adults. J Med Assoc Thai 1991;74:437-42.
- Zhang CY, Tan BK. Mechanisms of cardiovascular activity of Andrographis paniculata in the anaesthetized rat. J Ethnopharmacol 1997;56:97-101. PubMed
- Zhao HY, Fang WY. Antithrombotic effects of Andrographis paniculata nees in preventing myocardial infarction. Chin Med J (Engl) 1991;104:770-5.
- Amroyan E, Gabrielian E, Panossian A, et al. Inhibitory effect of andrographolide from Andrographis paniculata on PAF-induced platelet aggregation. Phytomedicine 1999;6:27-31. PubMed
- Zhang C, Kuroyangi M, Tan BK. Cardiovascular activity of 14-deoxy-11,12-didehydroandrographolide in the anaesthetised rat and isolated right atria. Pharmacol Res 1998;38:413-7. PubMed
- Puri A, Saxena R, Saxena RP, et al. Immunostimulant agents from Andrographis paniculata. J Nat Prod 1993;56:995-9. PubMed
- Melchoir J, Spasov AA, Ostrovskij OV, et al. Double-blind, placebo-controlled pilot and phase III study of activity of standardized Andrographis paniculata Herba Nees extract fixed combination (Kan Jang) in the treatment of uncomplicated upper-respirator
- Calabrese C, Berman SH, Babish JG, et al. A phase I trial of andrographolide in HIV positive patients and normal volunteers. Phytother Res 2000;14:333-8. PubMed
- Gabrielian ES, Shukarian AK, Goukasova GI, et al. A double blind, placebo-controlled study of Andrographis paniculata fixed combination Kan Jang in the treatment of acute upper respiratory tract infections including sinusitis. Phytomedicine 2002;9:589-97 PubMed
- Poolsup N, Suthisisang C, Prathanturarug S, et al. Andrographis paniculata in the symptomatic treatment of uncomplicated upper respiratory tract infection: systematic review of randomized controlled trials. J Clin Pharm Ther 2004;29:37-45. PubMed
- Coon JT, Ernst E. Andrographis paniculata in the treatment of upper respiratory tract infections: a systematic review of safety and efficacy. Planta Med 2004;70:293-8.
- Kligler, B., Ulbricht, C., Basch, E., Kirkwood, C. D., Abrams, T. R., Miranda, M., Singh Khalsa, K. P., Giles, M., Boon, H., and Woods, J. Andrographis paniculata for the treatment of upper respiratory infection: a systematic review by the natural standa
- Burgos, R. A., Hancke, J. L., Bertoglio, J. C., Aguirre, V., Arriagada, S., Calvo, M., and Caceres, D. D. Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms: a prospective randomized placebo-controlled tria
- Saxena, R. C., Singh, R., Kumar, P., Yadav, S. C., Negi, M. P., Saxena, V. S., Joshua, A. J., Vijayabalaji, V., Goudar, K. S., Venkateshwarlu, K., and Amit, A. A randomized double blind placebo controlled clinical evaluation of extract of Andrographis pa
- Tang, T., Targan, S. R., Li, Z. S., Xu, C., Byers, V. S., and Sandborn, W. J. Randomised clinical trial: herbal extract HMPL-004 in active ulcerative colitis - a double-blind comparison with sustained release mesalazine. Aliment.Pharmacol Ther 2011;33(2) PubMed
- Sandborn, W. J., Targan, S. R., Byers, V. S., Rutty, D. A., Mu, H., Zhang, X., and Tang, T. Andrographis paniculata extract (HMPL-004) for active ulcerative colitis. Am J Gastroenterol. 2013;108(1):90-98. PubMed
- Melchior, J., Palm, S., and Wikman, G. Controlled clinical study of standardized Andrographis paniculata extract in common cold - a pilot trial. Phytomedicine. 1997;3(4):315-318. PubMed
- Balap A, Atre B, Lohidasan S, et al. Pharmacokinetic and pharmacodynamic herb-drug interaction of Andrographis paniculata (Nees) extract and andrographolide with etoricoxib after oral administration in rats. J Ethnopharmacol. 2016 May 13;183:9-17. PubMed
- Bertoglio JC, Baumgartner M, Palma R, et al. Andrographis paniculata decreases fatigue in patients with relapsing-remitting multiple sclerosis: a 12-month double-blind placebo-controlled pilot study. BMC Neurol. 2016; 16(1):77. PubMed
- Suwankesawong W, Saokaew S, Permsuwan U, et al. Characterization of hypersensitivity reactions reported among Andrographis paniculata users in Thailand using Health Product Vigilance Center (HPVC) database. BMC Complement Altern Med. 2014; 14:515. PubMed
- Ciampi E, Uribe-San-Martin R, Cárcamo C, et al. Efficacy of andrographolide in not active progressive multiple sclerosis: a prospective exploratory double-blind, parallel-group, randomized, placebo-controlled trial. BMC Neurol 2020;20(1):173. PubMed
- Worakunphanich W, Thavorncharoensap M, Youngkong S, Thadanipon K, Thakkinstian A. Safety of Andrographis paniculata: A systematic review and meta-analysis. Pharmacoepidemiol Drug Saf 2021;30(6):727-739.
- More SJ, Tandulwadkar SS, Balap AR, Lohidasan S, Sinnathambi A, Mahadik KR. Effect of Andrographis paniculata extract and Andrographolide on the pharmacokinetics of Aceclofenac and Celecoxib in rats. Futur J Pharm Sci. 2023;9(1):1. PubMed
- Sundhani E, Nugroho AE, Nurrochmad A, Puspitasari I, Amalia Prihati D, Lukitaningsih E. Pharmacokinetic Herb-Drug Interactions of Glipizide with Andrographis paniculata (Burm. f.) and Andrographolide in Normal and Diabetic Rats by Validated HPLC Method. M PubMed
- Shang YX, Shen C, Stub T, et al. Adverse Effects of Andrographolide Derivative Medications Compared to the Safe use of Herbal Preparations of Andrographis paniculata: Results of a Systematic Review and Meta-Analysis of Clinical Studies. Front Pharmacol 20 PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC