Parasite Formula Ingredients & Drug Interactions
by BIOVEA
What is this page for?
First and foremost: checking Parasite Formula against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Parasite Formula is a dietary supplement by BIOVEA with 5 active ingredients. Its ingredients are commonly taken for diarrhea and digestive upset, sore throat and cold symptoms, gum and mouth rinse (gargle).Based on those ingredients, 1,054 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Clove, Quassia. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Parasite Formula by BIOVEA
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AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Parasite Formula by BIOVEA
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
BIOVEA's Parasite Formula is a liquid blend with 5 active ingredients. The formula contains bayberry, organic clove, green black walnuts, and quassia—each traditionally used for various purposes.
We could not check fresh garrya as we hold no data for it. The product also contains grain alcohol and deionized water as inactive ingredients.
Does it work?
Not established
The evidence base for this product is limited. Clove has possibly effective evidence for ventilator-associated pneumonia, but for cough, pain, and indigestion the evidence is insufficient.
Black walnut, bayberry, and quassia all have insufficient evidence for their respective uses. We do not hold effectiveness data on fresh garrya.
How safe is it?
Well-documented data
Several ingredients in this formula carry safety cautions. Bayberry has limited safety data and may irritate the stomach in large amounts; the safety data advises against it during pregnancy and breastfeeding.
Clove is well tolerated as a food spice but concentrated doses can be irritating or toxic, especially in children—even small amounts of clove oil can cause serious effects. Black walnut has limited human data and is best avoided in pregnancy; it may cause gastrointestinal upset due to tannins and can trigger allergic reactions in people with tree nut allergies.
Quassia may irritate the digestive tract at medicinal doses and is likely unsafe in pregnancy. The safety data advises against quassia during breastfeeding as well.
Meds to double-check
Moderate interaction found
Check before taking if you use antidiabetes drugs (clove and quassia may lower blood sugar), diuretics (quassia may worsen potassium loss), drugs metabolized by your liver's CYP2D6, CYP1A2, CYP3A4, or CYP2C9 enzymes (clove may raise their levels), digoxin or other heart medications (quassia may affect them), blood thinners or antiplatelet drugs like warfarin or aspirin (clove may increase bleeding risk), or acid-reducing drugs like omeprazole, ranitidine, or cimetidine (quassia may reduce their effectiveness). Discuss with your pharmacist or doctor before combining.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
This product combines traditional herbal ingredients with limited modern evidence and notable safety concerns, particularly around digestive irritation and pregnancy/breastfeeding use. If you take antidiabetes drugs, blood thinners, diuretics, heart medications, or acid-reducing drugs, you'll want to check your specific medications before starting.
Talk with your doctor or pharmacist about whether this product is right for your situation.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 23, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Parasite Formula, straight from the product label.
| Brand | BIOVEA |
|---|---|
| Barcode (UPC) | 818423023557 |
| Net contents | 1 Fluid Ounce(s); 30 mL |
| Market status | On market |
| Date entered into DSLD | Jun 23, 2021 |
| DSLD ID | 249299 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Kosher, Women (not pregnant or lactating), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Parasite Formula by BIOVEA, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 577 mg | -- |
| Bayberry | 0 NP | -- |
| organic Clove | 0 NP | -- |
| Green Black Walnuts | 0 NP | -- |
| Quassia | 0 NP | -- |
| fresh Garrya | 0 NP | -- |
Other ingredients: Grain Alcohol, deionized Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols
GMP Compliant
K Parve K-1604
Formulation
Non-GMO Gluten free
General Statements
Premium quality guaranteed since 2001. BIOVEA is committed to product quality to support you and your family's wellness goals. Because we feel so strongly about the quality, potency and purity of our products, we 100% guarantee your satisfaction with every purchase.
Guaranteed premium quality
Liquid extract
Suggested/Recommended/Usage/Directions
Suggested Daily Intake: Take 30 drops, 1-3 times per day, or as needed in juice or water.
Shake well before using.
Precautions
Warning: Do not take during pregnancy.
Keep out of reach of children.
Do not use this product if the safety seal on the bottle is broken.
Contains: Tree nut (walnut).
Formula
K Parve K-1604
FDA Statement of Identity
Herbal Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Parasite Formula by BIOVEA label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Parasite Formula by BIOVEA
These are the 5 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
- › Bayberry
- › Organic Clove
- › Green Black Walnuts
- › Quassia
- › Fresh Garrya
Other (inactive) ingredients: Grain Alcohol, Deionized Water. These complete the product’s ingredient list but are not active constituents.
Parasite Formula by BIOVEA Drug Interactions
HelloPharmacist Interaction Report
BIOVEA's Parasite Formula interacts with medications through its clove and quassia content.
The most serious interaction is clove's potential to increase the risk of low blood sugar (hypoglycemia) when combined with antidiabetes drugs—a moderate-severity concern that may require dosing adjustments to your insulin or oral blood sugar medications.
Read the full breakdown — every affected drug type, severity by severity
Clove may also increase blood levels of drugs metabolized by your liver's CYP2D6, CYP1A2, CYP3A4, and CYP2C9 enzymes (Moderate severity for each). These include many common medications—heart drugs, antidepressants, antihistamines, and others.
Additionally, clove theoretically raises the risk of bleeding if you're on blood thinners or antiplatelet drugs like warfarin or aspirin (Minor severity).
Quassia carries moderate interactions with antidiabetes drugs (same low-blood-sugar concern as clove) and diuretics—overuse may worsen potassium loss, which is especially risky if you take water pills. Quassia also theoretically affects digoxin (a heart medication) and may reduce effectiveness of acid-reducing drugs like omeprazole, ranitidine, or cimetidine (all Minor to Moderate severity).
We could not check fresh garrya because we hold no data for it. Altogether, these interactions span 1,055 individual medications.
Before you start this product, check your exact medications with the search tool on this page, and confirm with your doctor or pharmacist that it's safe to combine.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Parasite Formula?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Parasite Formula interact with 1,054 drugs. Click any drug to see the details.
2 of the 5 ingredients in Parasite Formula interact with drugs. Each result below shows which ingredient is responsible. organic Clove Quassia
Aspirin, Caffeine, Dihydrocodeine BitartrateSynalgos DC
How Aspirin, Caffeine, Dihydrocodeine Bitartrate interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
Organic CloveAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Theoretically, clove oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Organic Clove + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAspirin, Caffeine, Dover's PwdAcedoval, Dovacet
How Aspirin, Caffeine, Dover's Pwd interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
Organic CloveCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP1A2.
Read the full Organic Clove + Aspirin, Caffeine, Dover's Pwd interactionAspirin, Caffeine, HydrocodoneDamason-P
How Aspirin, Caffeine, Hydrocodone interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
Organic CloveCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP3A4.
Read the full Organic Clove + Aspirin, Caffeine, Hydrocodone interactionAspirin, Caffeine, Isobutylallylbarbituric Acid, PhenacetinLanorinal
How Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
Organic CloveAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, clove oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Organic Clove + Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interactionAspirin, Caffeine, OrphenadrineInvagesic, Invagesic Forte, Norgesic, Norgesic Forte, Orphengesic, Orphengesic Forte
How Aspirin, Caffeine, Orphenadrine interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
Organic CloveCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP1A2.
Read the full Organic Clove + Aspirin, Caffeine, Orphenadrine interactionAspirin, Caffeine, Phenacetin, PropoxypheneMargesic Comp. 65
How Aspirin, Caffeine, Phenacetin, Propoxyphene interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
Organic CloveAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
Theoretically, clove oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Organic Clove + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionAspirin, Carisoprodol, Codeine PhosphateSoma Compound w/ Codeine
How Aspirin, Carisoprodol, Codeine Phosphate interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
Organic CloveAnticoagulant/antiplatelet Drugs, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, clove oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Organic Clove + Aspirin, Carisoprodol, Codeine Phosphate interactionAspirin, Chlorpheniramine, PhenylpropanolamineAlka-Seltzer Plus Cold
How Aspirin, Chlorpheniramine, Phenylpropanolamine interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
Organic CloveAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, clove oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Organic Clove + Aspirin, Chlorpheniramine, Phenylpropanolamine interactionAspirin, Codeine PhosphateAspirin w/ Codeine
How Aspirin, Codeine Phosphate interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
Organic CloveCytochrome P450 2d6 (cyp2d6) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP2D6.
Read the full Organic Clove + Aspirin, Codeine Phosphate interactionAspirin, Codeine Phosphate, MethocarbamolRobaxisal C
How Aspirin, Codeine Phosphate, Methocarbamol interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
Organic CloveAnticoagulant/antiplatelet Drugs, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, clove oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Organic Clove + Aspirin, Codeine Phosphate, Methocarbamol interactionAspirin, Codeine Phosphate, PhenobarbitalPhenaphen
How Aspirin, Codeine Phosphate, Phenobarbital interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
Organic CloveCytochrome P450 2d6 (cyp2d6) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP2D6.
Read the full Organic Clove + Aspirin, Codeine Phosphate, Phenobarbital interactionAspirin, HydrocodoneAlor 5 500, Lortab ASA
How Aspirin, Hydrocodone interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
Organic CloveAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, clove oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Organic Clove + Aspirin, Hydrocodone interactionAspirin, OmeprazoleYosprala
How Aspirin, Omeprazole interacts with Parasite Formula — through 2 ingredients. Tap an ingredient for the detail:
Organic CloveAnticoagulant/antiplatelet Drugs, Cytochrome P450 2c9 (cyp2c9) Substrates +1 Moderate
Interaction Summary
Theoretically, clove oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Organic Clove + Aspirin, Omeprazole interactionQuassiaProton Pump Inhibitors (ppis) Minor
Interaction Summary
Theoretically, due to reports that quassia increases stomach acid, quassia might decrease the effectiveness of PPIs.
Read the full Quassia + Aspirin, Omeprazole interactionAspirin, OxycodonePercodan
How Aspirin, Oxycodone interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
Organic CloveCytochrome P450 2d6 (cyp2d6) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP2D6.
Read the full Organic Clove + Aspirin, Oxycodone interactionAspirin, PentazocineTalwin Compound
How Aspirin, Pentazocine interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
Organic CloveAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, clove oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Organic Clove + Aspirin, Pentazocine interactionAtazanavirReyataz
How Atazanavir interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
Organic CloveCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP3A4.
Read the full Organic Clove + Atazanavir interactionAtazanavir, CobicistatEvotaz
How Atazanavir, Cobicistat interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
Organic CloveCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP3A4.
Read the full Organic Clove + Atazanavir, Cobicistat interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
QuassiaDiuretic Drugs Moderate
Interaction Summary
Overuse of quassia might compound diuretic-induced potassium loss.
Read the full Quassia + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
QuassiaDiuretic Drugs Moderate
Interaction Summary
Overuse of quassia might compound diuretic-induced potassium loss.
Read the full Quassia + Atenolol, Chlorthalidone interactionAtogepantQulipta
How Atogepant interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
Organic CloveCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP3A4.
Read the full Organic Clove + Atogepant interactionAtomoxetineStrattera
How Atomoxetine interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
Organic CloveCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP2D6.
Read the full Organic Clove + Atomoxetine interactionAtorvastatinAtorvaliq
How Atorvastatin interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
Organic CloveCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP3A4.
Read the full Organic Clove + Atorvastatin interactionAtorvastatin CalciumLipitor
How Atorvastatin Calcium interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
Organic CloveCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP3A4.
Read the full Organic Clove + Atorvastatin Calcium interactionAtropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, ScopolamineAtrohist Plus, Pro Tuss, Ru-tuss, Stahist
How Atropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, Scopolamine interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
Organic CloveCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP3A4.
Read the full Organic Clove + Atropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, Scopolamine interactionAtropine, MeperidineAtropine, Meperidine
How Atropine, Meperidine interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
Organic CloveCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP2D6.
Read the full Organic Clove + Atropine, Meperidine interactionAtropine, Morphine SulfateAtropine, Morphine Sulfate
How Atropine, Morphine Sulfate interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
Organic CloveCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP2D6.
Read the full Organic Clove + Atropine, Morphine Sulfate interactionAvacopanTavneos
How Avacopan interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
Organic CloveCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP3A4.
Read the full Organic Clove + Avacopan interactionAvanafilStendra
How Avanafil interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
Organic CloveCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP3A4.
Read the full Organic Clove + Avanafil interactionAvapritinibAyvakit
How Avapritinib interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
Organic CloveCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP3A4.
Read the full Organic Clove + Avapritinib interactionAxitinibInlyta
How Axitinib interacts with Parasite Formula — through 1 ingredient. Tap an ingredient for the detail:
Organic CloveCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP3A4.
Read the full Organic Clove + Axitinib interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Parasite Formula with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
organic Clove
Antidiabetes Drugs
Theoretically, concomitant use of clove extracts with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical and laboratory research suggest that polyphenol extracts from clove flower buds might lower blood glucose levels. Dosing adjustments for insulin or oral hypoglycemic agents may be necessary when taken with clove. Monitor blood glucose levels closely.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP1A2.
In vitro research shows that eugenol, the principal constituent of clove, can inhibit CYP1A2 in a dose-dependent manner,. This effect has not been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP2C9.
In vitro research shows that eugenol, the principal constituent of clove, inhibits CYP2C9 in a dose-dependent manner. This effect has not been reported in humans.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP2D6.
In vitro research shows that eugenol, the principal constituent of clove, can inhibit CYP2D6 in a dose-dependent manner. This effect has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, concomitant use of clove may increase levels of drugs metabolized by CYP3A4.
In vitro research shows that eugenol, the principal constituent of clove, can inhibit CYP3A4 in a dose-dependent manner. This effect has not been reported in humans.
Anticoagulant/Antiplatelet Drugs
Theoretically, clove oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Laboratory research suggests that eugenol, a constituent of clove, has antiplatelet activity. This interaction has not been reported in humans.
Ibuprofen (Advil, Others)
Theoretically, topical application of clove oil with ibuprofen might increase the absorption and side effects of topical ibuprofen.
Laboratory research shows that topical application of clove oil increases the absorption of topical ibuprofen. This interaction has not been reported in humans.
Quassia
Antidiabetes Drugs
In animals, quassia extract reduced levels of fasting glucose. Theoretically, quassia might have additive effects when used with antidiabetes drugs. This might increase the risk of hypoglycemia in some patients. Monitor blood glucose levels closely.
Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, metformin (Glucophage), pioglitazone (Actos), rosiglitazone (Avandia), and others.
Digoxin (Lanoxin)
Theoretically, concomitant use with cardiac medications might increase the risk of therapeutic and adverse effects.
Diuretic Drugs
Overuse of quassia might compound diuretic-induced potassium loss. There is some concern that people taking quassia along with potassium depleting diuretics might have an increased risk for hypokalemia. Initiation of potassium supplementation or an increase in potassium supplement dose may be necessary for some patients.
Some diuretics that can deplete potassium include chlorothiazide (Diuril), chlorthalidone (Thalitone), furosemide (Lasix), and hydrochlorothiazide (HCTZ, Hydrodiuril, Microzide), and others.
Antacids
Theoretically, due to reports that quassia increases stomach acid, quassia might decrease the effectiveness of antacids.
H2-Blockers
Theoretically, due to reports that quassia increases stomach acid, quassia might decrease the effectiveness of H2-blockers. The H2 blockers include cimetidine (Tagamet), ranitidine (Zantac), nizatidine (Axid), and famotidine (Pepcid).
Proton Pump Inhibitors (Ppis)
Theoretically, due to reports that quassia increases stomach acid, quassia might decrease the effectiveness of PPIs. PPIs include omeprazole (Prilosec), lansoprazole (Prevacid), rabeprazole (Aciphex), pantoprazole (Protonix), and esomeprazole (Nexium).
Brand information
Manufacturer and brand details for Parasite Formula, from the product label.
BIOVEA
See all BIOVEA products- Name
- BIOVEA
- Street Address
- 9160 E. Bahia Dr.
- City
- Scottsdale
- State
- AZ
- ZipCode
- 85260
- Web Address
- www.biovea.com
Parasite Formula by BIOVEA: Common Questions
Does Parasite Formula by BIOVEA interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is this safe during pregnancy or breastfeeding?
What's clove supposed to do in this formula?
Can this cause stomach upset?
Is this safe if I have a tree nut allergy?
What does black walnut do?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Parasite Formula is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Parasite Formula’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Bayberry
Bayberry is a traditional herb used mainly as an astringent for diarrhea, sore throats, and minor skin or gum problems, but there is very little modern human research to confirm it works. It...
Read the full Bayberry monograph → Herb & supplement monographClove
Interacts with 977 drugsClove is a common cooking spice that is also used in traditional medicine, especially as a topical numbing agent for tooth pain thanks to its main compound, eugenol. Food amounts are general...
Read the full Clove monograph → Herb & supplement monographBlack Walnut
Black walnut is a tree whose green hulls are traditionally used as a natural antiparasitic and digestive remedy, but solid human evidence for these uses is lacking. It contains a compound ca...
Read the full Black Walnut monograph → Herb & supplement monographQuassia
Interacts with 198 drugsQuassia is a tropical wood known for its very bitter taste, traditionally used as a digestive bitter and as a folk remedy for parasites and head lice. Human evidence for these uses is limite...
Read the full Quassia monograph →Sources & How We Checked
Parasite Formula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Bayberry 3 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
Clove 26 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Kanerva L, Estlander T, Jolanki R. Occupational allergic contact dermatitis from spices. Contact Dermatitis 1996;35:157-62. PubMed
- Chen SJ, Wang MH, Chen IJ. Antiplatelet and calcium inhibitory properties of eugenol and sodium eugenol acetate. Gen Pharmacol 1996;27:629-33. PubMed
- Malson JL, Lee EM, Murty R, et al. Clove cigarette smoking: biochemical, physiological, and subjective effects. Pharmacol Biochem Behav 2003;74:739-45. PubMed
- Kirsch CM, Yenokida GG, Jensen WA, et al. Non-cardiogenic pulmonary oedema due to the intravenous administration of clove oil. Thorax 1990;45:235-6. PubMed
- Pallares, D. E. Link between clove cigarettes and urticaria? Postgrad.Med 10-1-1999;106(4):153. PubMed
- Barnard, D. R. Repellency of essential oils to mosquitoes (Diptera: Culicidae). J Med Entomol. 1999;36(5):625-629. PubMed
- Sanchez-Perez, J. and Garcia-Diez, A. Occupational allergic contact dermatitis from eugenol, oil of cinnamon and oil of cloves in a physiotherapist. Contact Dermatitis 1999;41(6):346-347. PubMed
- Andersen, K. E., Johansen, J. D., Bruze, M., Frosch, P. J., Goossens, A., Lepoittevin, J. P., Rastogi, S., White, I., and Menne, T. The time-dose-response relationship for elicitation of contact dermatitis in isoeugenol allergic individuals. Toxicol.Appl PubMed
- Alqareer, A., Alyahya, A., and Andersson, L. The effect of clove and benzocaine versus placebo as topical anesthetics. J Dent 2006;34(10):747-750. PubMed
- Lane, B. W., Ellenhorn, M. J., Hulbert, T. V., and McCarron, M. Clove oil ingestion in an infant. Hum.Exp Toxicol. 1991;10(4):291-294. PubMed
- Quirce, S., Fernandez-Nieto, M., del, Pozo, V, Sastre, B., and Sastre, J. Occupational asthma and rhinitis caused by eugenol in a hairdresser. Allergy 2008;63(1):137-138. PubMed
- Srivastava, K. C. and Malhotra, N. Acetyl eugenol, a component of oil of cloves (Syzygium aromaticum L.) inhibits aggregation and alters arachidonic acid metabolism in human blood platelets. Prostaglandins Leukot.Essent.Fatty Acids 1991;42(1):73-81. PubMed
- Dyrbye, B. A., Dubois, L., Vink, R., and Horn, J. A patient with clove oil intoxication. Anaesth.Intensive Care 2012;40(2):365-366.
- Guidotti, T. L., Laing, L., and Prakash, U. B. Clove cigarettes. The basis for concern regarding health effects. West J Med 1989;151(2):220-228.
- Anonymous. Evaluation of the health hazard of clove cigarettes. Council on Scientific Affairs. JAMA 12-23-1988;260(24):3641-3644. DOI
- Romaguera, C., Alomar, A., Camarasa, J. M., Garcia, Bravo B., Garcia, Perez A., Grimalt, F., Guerra, P., Lopez, Gorretcher B., Pascual, A. M., Miranda, A., and . Contact dermatitis in children. Contact Dermatitis 1985;12(5):283-284. PubMed
- Hackett, P. H., Rodriguez, G., and Roach, R. C. Clove cigarettes and high-altitude pulmonary edema. JAMA 6-28-1985;253(24):3551-3552. DOI
- Isaacs, G. Permanent local anaesthesia and anhidrosis after clove oil spillage. Lancet 4-16-1983;1(8329):882. PubMed
- Saeed, S. A. and Gilani, A. H. Antithrombotic activity of clove oil. J Pak Med Assoc 1994;44(5):112-115.
- Hartnoll, G., Moore, D., and Douek, D. Near fatal ingestion of oil of cloves. Arch.Dis Child 1993;69(3):392-393. PubMed
- Srivastava, K. C. Antiplatelet principles from a food spice clove (Syzygium aromaticum L) [corrected]. Prostaglandins Leukot.Essent.Fatty Acids 1993;48(5):363-372.
- Jiang Q, Wu Y, Zhang H, et al. Development of essential oils as skin permeation enhancers: penetration enhancement effect and mechanism of action. Pharmaceutical Biol. 2017;55(1):1592-1600. PubMed
- Mohan R, Jose S, Mulakkal J, Karpinsky-Semper D, Swick AG, Krishnakumar IM. Water-soluble polyphenol-rich clove extract lowers pre- and post-prandial blood glucose levels in healthy and prediabetic volunteers: an open label pilot study. BMC Complement Alt PubMed
- Alharbi NFM, Ahad A, Bin Jardan YA, Al-Jenoobi FI. Effect of eugenol on cytochrome P450 1A2, 2C9, 2D6, and 3A4 activity in human liver microsomes. Saudi Pharm J 2024;32(7):102118. PubMed
Black Walnut 3 references
- Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Food and Drug Administration. Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA); Public Law 108-282, Title II. Accessed on May 19, 2021. Available at: https://www.fda.gov/food/food-allergensgluten-free-guidance-documents-regulatory-infor
Quassia 8 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Robbers JE, Speedie MK, Tyler VE. Pharmacognosy and Pharmacobiotechnology. Baltimore, MD: Williams & Wilkins, 1996.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Jensen O, Nielsen AO, Bjerregaard P. Pediculosis capitis treated with quassia tincture. Acta Derm Venereol 1978;58:557-9. DOI
- Diehl C, Ferrari A. Efficacy of topical 4% Quassia amara gel in facial seborrheic dermatitis:a randomized, double-blind, comparative study. J Drugs Dermatol. 2013;12(3):312-5.
- Ferrari A, Diehl C. Evaluation of the efficacy and tolerance of a topical gel with 4% quassia extract in the treatment of rosacea. J Clin Pharmacol. 2012;52(1):84-8. PubMed
- Husain GM, Singh PN, Singh RK, Kumar V. Antidiabetic activity of standardized extract of Quassia amara in nicotinamide-streptozotocin-induced diabetic rats. Phytother Res. 2011;25(12):1806-12.
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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