Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Peak 400 ATP Lemon Lime Ingredients & Drug Interactions

by ProMera Sports

Powder Category: Non-nutrient/non-botanical
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

Peak 400 ATP Lemon Lime is a dietary supplement by ProMera Sports with 1 active ingredient. Its ingredients are commonly taken for energy and cellular function support, athletic performance and muscle energy, circulation support.Based on those ingredients, 47 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Adenosine 5'Triphosphate Disodium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Peak 400 ATP Lemon Lime by ProMera Sports

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Peak 400 ATP contains one active ingredient: adenosine 5'-triphosphate (ATP) disodium, a compound your cells naturally use for energy. The powder also includes maltodextrin, citric acid, natural and artificial flavors, silicon dioxide, and sucralose as inactive ingredients to create the lemon-lime flavor and shelf stability.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Athletic performance enhancement and recovery.
  • We looked for evidence on: Athletic performance, Muscle strength, Endurance, Exercise recovery.
  • The closest evidence on file: Adenosine is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).

In the data we hold, adenosine is rated effective for two uses: stopping paroxysmal supraventricular tachycardia (an abnormal rapid heart rhythm that comes and goes) and aiding cardiovascular disease diagnosis during cardiac stress testing. Both of these are medical applications given by prescription injection under a doctor's supervision.

The facts we have don't establish effectiveness for this oral supplement form for any condition, and the safety notes emphasize that oral supplement evidence is limited.

The evidence, ingredient by ingredient Adenosine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

This is a critical point: adenosine's safety profile comes from the prescription injectable form, which is powerful and used only in medical settings by trained professionals. The facts note that oral or intramuscular adenosine hasn't reported adverse effects in trials, but a thorough safety evaluation hasn't been done.

The safety data advises against supplement use during pregnancy, and there isn't enough information to know whether it's safe while breastfeeding—talk with your doctor or pharmacist before use if either applies to you. The prescription intravenous form can cause chest pain, dizziness, shortness of breath, facial flushing, and headache, and rarely serious heart rhythm problems.

How an oral supplement would behave is not well established.

Side effects, ingredient by ingredient Adenosine

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Adenosine.
  • The most serious interaction on file is rated Major.
  • For scale: 47 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Stop and check with your pharmacist before taking Peak 400 ATP if you're on dipyridamole (Persantine)—this is a Major interaction that can cause serious heart and blood pressure effects. Also double-check carbamazepine (Tegretol) for seizure control, as it raises the risk of heart block.

Avoid taking this product within 24 hours of caffeine, aminophylline, or theophylline, as they block adenosine's effects.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This product is adenosine in oral supplement form, a compound normally given by injection for specific heart conditions in medical settings. If you take dipyridamole, carbamazepine, or methylxanthines (caffeine, theophylline, aminophylline), check with your pharmacist before starting.

Because oral adenosine supplement safety hasn't been thoroughly studied, and you're pregnant or breastfeeding, talk with your doctor first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Peak 400 ATP Lemon Lime, straight from the product label.

Brand ProMera Sports
Barcode (UPC) 682676734306
Net contents 1.27 oz.; 36 Gram(s)
Market status On market
Date entered into DSLD Aug 25, 2015
DSLD ID 49337
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Peak 400 ATP Lemon Lime by ProMera Sports, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1.2 Gram(s)
Maximum serving Sizes:
2.4 Gram(s)
Servings per container
30
UPC/BARCODE
682676734306
IngredientAmount% DV
Adenosine 5'Triphosphate Disodium400 mg--

Other ingredients: Maltodextrin, Citric Acid, Natural and Artificial flavors, Silicon Dioxide, Sucralose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Recovery Strength Performance Pre-Workout AM Pre workout Intra workout Post workout PM

Athletic Performance Enhancer

Naturally Flavored

Pre Workout 30 servings

Daily use of this product can help promote: ~ Improve blood flow ~ Improved muscular excitability ~ Improved recovery ~ Improved Performance

Note: Contents may settle during shipping.

NPN #80054219

Manufactured in the U.S.A. from international and domestic ingredients.

Dye Free

Research on file

Seals/Symbols

ProMera(R) Sports

PEAK ATP(R)

Brand IP Statement(s)

PEAK-ATP(R) is a registered trademark of TSI (USA), Inc. and is protected by U.S. Patents #7,629,329 and #7,671,038

The home of Con-Cret(R)

What is Peak 400(TM) ATP Peak 400(TM) ATP contains Peak ATP(R), a clinically studied form of oral ATP (Adenosine 5'-Triphosphate Disodium). Peak 400(TM) ATP is not creatine. Amazingly effective when used as a standalone or in combination with other pre-workouts. The addition of Peak 400 ATP(TM) to any pre-workout supplement will dramatically improve athletic performance. Peak 400 ATP(TM) is perfect for both men and women.

(C)2015 All Rights Reserved.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Suggested/Recommended/Usage/Directions

Suggested use: Adults, mix one serving (full clinical dose) with 4-6 ounces of water 30-45 minutes prior to training. For best results, take on an empty stomach. Do not take more than 2 servings in a 24 hour period.

Shake well before use.

Precautions

Warnings: Not intended for individuals under the age of 18.

Consult your physician before using this product and if you are taking any prescription or over the counter medications or supplements. Do not take if you are pregnant or nursing.

In the event of any adverse reaction discontinue use immediately and consult a physician.

Keep out of reach of children.

Storage

Store in a cool dry place.

FDA Statement of Identity

Dietary Supplement

General

REV 2015

See for yourself

Peak 400 ATP Lemon Lime by ProMera Sports label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Peak 400 ATP Lemon Lime by ProMera Sports

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1.2 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Adenosine 5'Triphosphate Disodium

Interacts with
47 drugs
400 mg per serving

Adenosine is a natural building block your body uses for energy and cell signaling, and a prescription injectable version is used by doctors to treat...

Adenosine 5'Triphosphate Disodium monograph & interactions

Other (inactive) ingredients: Maltodextrin, Citric Acid, Natural and Artificial flavors, Silicon Dioxide, Sucralose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Peak 400 ATP Lemon Lime by ProMera Sports Drug Interactions

Want to check YOUR meds against Peak 400 ATP Lemon Lime?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
47Drugs
2 Major 1 Moderate 44 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Peak 400 ATP Lemon Lime with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Adenosine 5'Triphosphate Disodium3 drug types · 47 drugs

Dipyridamole (Persantine)

Dipyridamole can increase the therapeutic and toxic effects of adenosine.
Dipyridamole decreases the metabolism of adenosine. Intravenous infusion of adenosine in patients who are taking dipyridamole can cause dizziness, bradycardia, and syncope. Dipyridamole should be discontinued for several days prior to a cardiac stress test using adenosine.

Likelihood Likely Evidence D
Carbamazepine (Tegretol)

Carbamazepine might increase the risk of heart block when used concomitantly with adenosine.
Carbamazepine and adenosine can both cause heart block. Giving them concurrently might produce an additive effect.

Likelihood Possible Evidence D
Methylxanthines

Methylxanthines are competitive antagonists of adenosine and can block its pharmacologic effects.
The methylxanthines, aminophylline, caffeine, and theophylline, can block the effects of adenosine by acting as competitive antagonists at adenosine cell surface receptors. It is recommended that methylxanthines be avoided for 24 hours prior to cardiac stress tests.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Peak 400 ATP Lemon Lime, from the product label.

Pharmacist Counseling Corner

Peak 400 ATP Lemon Lime by ProMera Sports: Common Questions

Does Peak 400 ATP Lemon Lime by ProMera Sports interact with any medications?
Yes. Based on its ingredients, Peak 400 ATP Lemon Lime has a known interaction with 47 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Peak 400 ATP Lemon Lime contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does adenosine in this supplement actually do?
Adenosine is a molecule your cells use for energy. In the prescription injectable form, it's effective at stopping a specific abnormal heart rhythm and helps doctors diagnose heart disease during stress tests. What it does in oral supplement form for otherwise healthy people isn't established in the data we hold.
Is it safe to take if I'm pregnant or breastfeeding?
The data advises against it during breastfeeding because there isn't enough safety information. For pregnancy, the facts don't provide a rating—that means there isn't enough data either way. Talk with your doctor or pharmacist before use if you're pregnant or nursing.
What side effects might I get?
The adverse effects documented are from the prescription intravenous form, which can cause chest pain, dizziness, shortness of breath, flushing, and headache. When adenosine is given orally or into muscle, no adverse effects have been reported, but a thorough safety study hasn't been done, so unknown risks may exist.
Can I take this with caffeine?
No—caffeine blocks adenosine's effects by competing at the same cell receptors. You should avoid caffeine for 24 hours before and after taking this product. The same goes for theophylline and aminophylline.
I'm scheduled for an adenosine stress test. Can I take this supplement?
Don't take this product before a cardiac stress test using adenosine. The injection form is already potent, and adding oral adenosine could interfere with the test. Ask your doctor or the testing facility what to do beforehand.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Peak 400 ATP Lemon Lime is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Peak 400 ATP Lemon Lime label
Go deeper

The Full Monographs Behind Peak 400 ATP Lemon Lime’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Peak 400 ATP Lemon Lime's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Adenosine 10 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Agteresch HJ, Dagnelie PC, van den Berg JW, Wilson JH. Adenosine triphosphate: established and potential clinical applications. Drugs 1999;58:211-32.. PubMed
  3. Agteresch HJ, Dagnelie PC, van der Gaast A, et al. Randomized clinical trial of adenosine 5'-triphosphate in patients with advanced non-small-cell lung cancer. J Natl Cancer Inst 2000;92:321-8.. PubMed
  4. Haskell CM, Wong M, Williams A, Lee LY. Phase I trial of extracellular adenosine 5'-triphosphate in patients with advanced cancer. Med Pediatr Oncol 1996;27:165-73.. DOI
  5. Haskell CM, Mendoza E, Pisters KM, et al. Phase II study of intravenous adenosine 5'-triphosphate in patients with previously untreated stage IIIB and stage IV non-small cell lung cancer. Invest New Drugs 1998;16:81-5.. PubMed
  6. Eisenach JC, Curry R, Hood DD. Dose response of intrathecal adenosine in experimental pain and allodynia. Anesthesiology 2002;97:938-42.. PubMed
  7. Agteresch HJ, Dagnelie PC, Rietveld T, et al. Pharmacokinetics of intravenous ATP in cancer patients. Eur J Clin Pharmacol 2000;56:49-55.. PubMed
  8. Underwood DA. Which medications should be held before a pharmacologic or exercise stress test? Cleve Clin J Med 2002;69:449-50. PubMed
  9. Litmann L, Anderson JD, Monroe MH. Adenosine and Aggrenox: A hazardous combination. Ann Intern Med 2002;137:E-76. PubMed
  10. Faghihi G, Iraji F, Rajaee Harandi M, et al. Comparison of the efficacy of topical minoxidil 5% and adenosine 0.75% solutions on male androgenic alopecia and measuring patient satisfaction rate. Acta Dermatovenerol Croat 2013;21(3):155-9.

See these in context on the Adenosine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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