Perfect Mushroom Immunity Powder Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Perfect Mushroom Immunity Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Perfect Mushroom Immunity Powder is a dietary supplement by Perfect Supplements with 3 active ingredients. Its ingredients are commonly taken for immune support, antioxidant support, general wellness/tonic.Based on those ingredients, 494 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Reishi Blend, Chaga. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Perfect Mushroom Immunity Powder by Perfect Supplements
Ask about any prescription or over-the-counter medication and we check it for interactions with Perfect Mushroom Immunity Powder by Perfect Supplements — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Perfect Mushroom Immunity Powder by Perfect Supplements
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Perfect Mushroom Immunity Powder contains three active ingredients: chaga, Turkey Tail, and Reishi Blend. Chaga and reishi are both medicinal mushrooms traditionally used to support immune function and overall wellness.
Turkey Tail is another functional mushroom added to the formula. There are no inactive ingredients listed for this product.
Does it work?
Not established
The evidence supporting these ingredients is limited. For chaga, we don't have enough reliable data to rate its effectiveness for heart disease, diabetes, or COVID-19.
Reishi mushroom shows possibly ineffective evidence for high cholesterol, and we lack solid data for altitude sickness, Alzheimer's disease, and athletic performance. We hold no effectiveness data for Turkey Tail.
Overall, the clinical evidence for this formula's benefits is not established in the sources we rely on.
How safe is it?
Well-documented data
Chaga is generally used in foods and teas, but human safety data are limited. There have been two cases of kidney failure and one case of kidney damage linked to excessive chaga use due to its high oxalate content.
Reishi mushroom is generally well tolerated short-term, though long-term safety isn't well studied. Common side effects include dizziness, dry mouth, itching, nausea, rash, stomach upset, sore throat, and runny nose.
Respiratory allergy to reishi spores can occur, and rare cases of insomnia and headache have been reported. Chaga and reishi should both be avoided during pregnancy and while breastfeeding—there isn't enough safety information to know they're safe in those situations.
Meds to double-check
Moderate interaction found
Check your exact medications if you take anticoagulant or antiplatelet drugs (blood thinners), antihypertensive drugs (blood pressure medications), antidiabetes drugs (diabetes medications), or immunosuppressants—all are Moderate concerns with ingredients in this powder. We could not check Turkey Tail against any medications.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
This powder is made from traditional medicinal mushrooms, but the clinical evidence for its benefits isn't solid in the data we hold. If you take blood thinners, blood pressure medications, antidiabetes drugs, or immunosuppressants, you'll want to check your specific medications with the tool on this page before starting.
Talk with your pharmacist or doctor, especially if you're pregnant, breastfeeding, or have kidney concerns.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Perfect Mushroom Immunity Powder, straight from the product label.
| Brand | Perfect Supplements |
|---|---|
| Barcode (UPC) | 793888502833 |
| Net contents | 144 Gram(s); 5 Ounce(s) |
| Market status | On market |
| Date entered into DSLD | Apr 24, 2025 |
| DSLD ID | 329223 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Perfect Mushroom Immunity Powder by Perfect Supplements, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Chaga | 800 mg | -- |
| Turkey Tail | 800 mg | -- |
| Reishi Blend | 800 mg | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Three simple ingredients: Made with the mycelial biomass & fruit body of 100% pure chaga, reishi, and turkey tail.
Mushroom Immunity is lab tested for a minimum of 360 mg of beta glucans per serving.
Chaga, reishi, & turkey tail
Formulation
Perfect health benefits: These mushrooms strengthen the body's natural defenses & healing mechanisms, and can increase general well-being.
Sustainable, ethical, transparent: Grown without toxic pesticides, fertilizers, or GMOs. Each batch is independently lab tested.
Organic USDA Organic Organic mushroom powder
Vegan
Gluten free Non-GMO
This product has been certified organic by Organic Certifiers Inc., under NOP Final Rule 7, CFR part 205. www.organiccertifiers.com
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Seals/Symbols
USDA Organic Vegan USA Grown Lab tested
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Usage: Add 1 tsp daily to liquids.
Storage
Store in a cool dry place.
Precautions
Manufactured in a facility that processes milk, egg, soy, tree nuts, fish, & shellfish.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Perfect Mushroom Immunity Powder by Perfect Supplements label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Perfect Mushroom Immunity Powder by Perfect Supplements
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Teaspoon(s) Dosage formPowder Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Chaga
Interacts with327 drugs
Chaga is a fungus that grows mostly on birch trees and is used as a tea or supplement, mainly for immune and antioxidant support. Human evidence for i...
Chaga monograph & interactionsTurkey Tail
Reishi Blend
Interacts with375 drugs
Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits...
Reishi Blend monograph & interactionsPerfect Mushroom Immunity Powder by Perfect Supplements Drug Interactions
HelloPharmacist Interaction Report
Perfect Mushroom Immunity Powder by Perfect Supplements contains two ingredients with documented interactions: chaga and reishi mushroom.
The most serious interactions are Moderate in severity and affect three major drug categories.
Read the full breakdown — every affected drug type, severity by severity
Chaga may increase bleeding risk if you take anticoagulant or antiplatelet drugs (blood thinners like warfarin or aspirin). It might also interfere with immunosuppressive medications used after transplants or for autoimmune conditions, and it could lower blood sugar too much if combined with antidiabetes drugs.
These effects come from lab and animal research; they haven't been confirmed in people yet.
Reishi mushroom carries similar Moderate concerns: high doses might increase bleeding risk with anticoagulants or antiplatelets, it could lower blood pressure too much with antihypertensive drugs, and it may add to the blood-sugar-lowering effect of antidiabetes medications. We could not check Turkey Tail for interactions—we hold no data on it.
Almogether, these interactions span 487 individual medications. Before you start this powder, run your exact prescriptions through the checker on this page.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Perfect Mushroom Immunity Powder?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Perfect Mushroom Immunity Powder interact with 494 drugs. Click any drug to see the details.
2 of the 3 ingredients in Perfect Mushroom Immunity Powder interact with drugs. Each result below shows which ingredient is responsible. Reishi Blend Chaga
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Perfect Mushroom Immunity Powder — through 1 ingredient. Tap an ingredient for the detail:
ChagaImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Chaga + 6-mercaptopurine interactionAbciximabReoPro
How Abciximab interacts with Perfect Mushroom Immunity Powder — through 2 ingredients. Tap an ingredient for the detail:
Reishi BlendAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Blend + Abciximab interactionChagaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Perfect Mushroom Immunity Powder — through 2 ingredients. Tap an ingredient for the detail:
Reishi BlendAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Blend + Abrocitinib interactionChagaAnticoagulant/antiplatelet Drugs, Immunosuppressants Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Perfect Mushroom Immunity Powder — through 2 ingredients. Tap an ingredient for the detail:
ChagaAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Chaga + Acarbose interactionReishi BlendAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Reishi Blend + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Perfect Mushroom Immunity Powder — through 1 ingredient. Tap an ingredient for the detail:
Reishi BlendAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Reishi Blend + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Perfect Mushroom Immunity Powder — through 2 ingredients. Tap an ingredient for the detail:
Reishi BlendAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Blend + Acenocoumarol interactionChagaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Perfect Mushroom Immunity Powder — through 2 ingredients. Tap an ingredient for the detail:
ChagaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga + Acetaminophen, Aspirin interactionReishi BlendAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Blend + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Perfect Mushroom Immunity Powder — through 2 ingredients. Tap an ingredient for the detail:
Reishi BlendAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Blend + Acetaminophen, Aspirin, Caffeine interactionChagaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Perfect Mushroom Immunity Powder — through 2 ingredients. Tap an ingredient for the detail:
Reishi BlendAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Blend + Acetaminophen, Ibuprofen interactionChagaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga + Acetaminophen, Ibuprofen interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Perfect Mushroom Immunity Powder — through 1 ingredient. Tap an ingredient for the detail:
Reishi BlendAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Reishi Blend + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Perfect Mushroom Immunity Powder — through 2 ingredients. Tap an ingredient for the detail:
ChagaAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Chaga + Acetohexamide interactionReishi BlendAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Reishi Blend + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Perfect Mushroom Immunity Powder — through 2 ingredients. Tap an ingredient for the detail:
ChagaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga + Acetylsalicylic Acid interactionReishi BlendAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Blend + Acetylsalicylic Acid interactionAdalimumabHumira
How Adalimumab interacts with Perfect Mushroom Immunity Powder — through 1 ingredient. Tap an ingredient for the detail:
ChagaImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Chaga + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with Perfect Mushroom Immunity Powder — through 1 ingredient. Tap an ingredient for the detail:
ChagaImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Chaga + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with Perfect Mushroom Immunity Powder — through 1 ingredient. Tap an ingredient for the detail:
ChagaImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Chaga + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with Perfect Mushroom Immunity Powder — through 1 ingredient. Tap an ingredient for the detail:
ChagaImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Chaga + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with Perfect Mushroom Immunity Powder — through 1 ingredient. Tap an ingredient for the detail:
ChagaImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Chaga + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with Perfect Mushroom Immunity Powder — through 1 ingredient. Tap an ingredient for the detail:
ChagaImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Chaga + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with Perfect Mushroom Immunity Powder — through 1 ingredient. Tap an ingredient for the detail:
ChagaImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Chaga + Adalimumab-fkjp interactionAlbiglutideTanzeum
How Albiglutide interacts with Perfect Mushroom Immunity Powder — through 2 ingredients. Tap an ingredient for the detail:
ChagaAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Chaga + Albiglutide interactionReishi BlendAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Reishi Blend + Albiglutide interactionAlefaceptAmevive
How Alefacept interacts with Perfect Mushroom Immunity Powder — through 1 ingredient. Tap an ingredient for the detail:
ChagaImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Chaga + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with Perfect Mushroom Immunity Powder — through 1 ingredient. Tap an ingredient for the detail:
ChagaImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Chaga + Alemtuzumab interactionAliskirenTekturna
How Aliskiren interacts with Perfect Mushroom Immunity Powder — through 1 ingredient. Tap an ingredient for the detail:
Reishi BlendAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Reishi Blend + Aliskiren interactionAlogliptinNesina
How Alogliptin interacts with Perfect Mushroom Immunity Powder — through 2 ingredients. Tap an ingredient for the detail:
Reishi BlendAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Reishi Blend + Alogliptin interactionChagaAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Chaga + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Perfect Mushroom Immunity Powder — through 2 ingredients. Tap an ingredient for the detail:
ChagaAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Chaga + Alogliptin, Metformin interactionReishi BlendAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Reishi Blend + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Perfect Mushroom Immunity Powder — through 2 ingredients. Tap an ingredient for the detail:
Reishi BlendAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Reishi Blend + Alogliptin, Pioglitazone interactionChagaAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Chaga + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Perfect Mushroom Immunity Powder — through 2 ingredients. Tap an ingredient for the detail:
Reishi BlendAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Blend + Alteplase, Tpa interactionChagaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Perfect Mushroom Immunity Powder — through 2 ingredients. Tap an ingredient for the detail:
ChagaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionReishi BlendAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Blend + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Perfect Mushroom Immunity Powder — through 2 ingredients. Tap an ingredient for the detail:
Reishi BlendAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Blend + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionChagaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Perfect Mushroom Immunity Powder — through 1 ingredient. Tap an ingredient for the detail:
Reishi BlendAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Reishi Blend + Ambrisentan interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Perfect Mushroom Immunity Powder with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Reishi Blend
Anticoagulant/Antiplatelet Drugs
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
A dose of 1.5 grams daily of reishi mushroom does not seem to decrease platelet aggregation, but a higher dose of 3 grams daily does.
Antidiabetes Drugs
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Animal research suggests that reishi mushroom decreases blood sugar. However, in patients with type 2 diabetes, taking reishi mushroom does not reduce fasting glucose levels, and its effects on glycated hemoglobin are inconsistent.
Antihypertensive Drugs
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Reishi mushroom has shown hypotensive activity in animal research. Clinical evidence suggests that reishi mushroom reduces blood pressure in some, but not all, patients with hypertension.
Chaga
Anticoagulant/Antiplatelet Drugs
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research suggests that chaga extract can inhibit platelet aggregation. This effect has not been reported in humans.
Antidiabetes Drugs
Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that chaga might decrease blood glucose levels and increase insulin levels. This has not been reported in humans.
Immunosuppressants
Theoretically, chaga might interfere with immunosuppressive therapy.
In vitro research suggests that certain constituents of chaga stimulate immune function. This has not been reported in humans.
Brand information
Manufacturer and brand details for Perfect Mushroom Immunity Powder, from the product label.
Perfect Supplements
See all Perfect Supplements products- Name
- Perfect Supplements, LLC
- Street Address
- PO Box 60070
- City
- Florence
- State
- MA
- ZipCode
- 01062
- Phone Number
- 1-866-802-3860
- Web Address
- www.perfectsupplements.com
Perfect Mushroom Immunity Powder by Perfect Supplements: Common Questions
Does Perfect Mushroom Immunity Powder by Perfect Supplements interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this powder if I'm pregnant or breastfeeding?
What are the most common side effects I might notice?
Is this powder clinically proven to boost immunity?
What is Turkey Tail in this formula?
Is reishi mushroom safe to take long-term?
Why does the product say chaga has high oxalate?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Perfect Mushroom Immunity Powder is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Perfect Mushroom Immunity Powder’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Chaga
Interacts with 327 drugsChaga is a fungus that grows mostly on birch trees and is used as a tea or supplement, mainly for immune and antioxidant support. Human evidence for its benefits is very limited, and it may...
Read the full Chaga monograph → Herb & supplement monographReishi Mushroom
Interacts with 375 drugsReishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits is limited or low-quality, so it should...
Read the full Reishi Mushroom monograph →Sources & How We Checked
Perfect Mushroom Immunity Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 26 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Chaga 9 references
- Sun JE, Ao ZH, Lu ZM, et al. Antihyperglycemic and antilipidperoxidative effects of dry matter of culture broth of Inonotus obliquus in submerged culture on normal and alloxan-diabetes mice. J Ethnopharmacol 2008;118(1):7-13. PubMed
- Hyun KW, Jeong SC, Lee DH, et al. Isolation and characterization of a novel platelet aggregation inhibitory peptide from the medicinal mushroom, Inonotus obliquus. Peptides 2006;27(6):1173-8. PubMed
- Kim YO, Han SB, Lee HW, et al. Immuno-stimulating effect of the endo-polysaccharide produced by submerged culture of Inonotus obliquus. Life Sci 2005;77(19):2438-56. PubMed
- Kikuchi Y, Seta K, Ogawa Y, et al. Chaga mushroom-induced oxalate nephropathy. Clin Nephrol 2014;81(6):440-4. PubMed
- Lee S, Lee HY, Park Y, et al. Development of end stage renal disease after long-term ingestion of chaga mushroom: case report and review of literature. J Korean Med Sci. 2020;35(19):e122.
- Kwon O, Kim Y, Paek JH, et al. Chaga mushroom-induced oxalate nephropathy that clinically manifested as nephrotic syndrome: A case report. Medicine (Baltimore) 2022;101(10):e28997. PubMed
- Su L, Xin C, Yang J, et al. A polysaccharide from Inonotus obliquus ameliorates intestinal barrier dysfunction in mice with type 2 diabetes mellitus. Int J Biol Macromol 2022;214:312-323. PubMed
- Chen S, Ma Y, Li H, et al. Anti-diabetic e?ects of Inonotus obliquus extract in high fat diet combined streptozotocin-induced type 2 diabetic mice. Nutr Hosp 2022;39(6):1256-1263. PubMed
- Ye X, Wu K, Xu L, et al. Methanol extract of Inonotus obliquus improves type 2 diabetes mellitus through modifying intestinal flora. Front Endocrinol (Lausanne) 2023;13:1103972. PubMed
Reishi Mushroom 17 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Tao J, Feng KY. Experimental and clinical studies on inhibitory effect of ganoderma lucidum on platelet aggregation. J Tongji Med Univ 1990;10:240-3. PubMed
- Singh AB, Gupta SK, Pereira BM, Prakash D. Sensitization to Ganoderma lucidum in patients with respiratory allergy in India. Clin Exp Allergy 1995;25:440-7.
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