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Dietary supplement

Pleurisy Root 450 mg Ingredients & Drug Interactions

by TerraVita Premium Collection

Pleurisy Root 450 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pleurisy Root 450 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Pleurisy Root 450 mg is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for respiratory congestion, pleurisy and chest discomfort, coughs and bronchitis.Based on those ingredients, 117 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Pleurisy Root. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Pleurisy Root 450 mg by TerraVita Premium Collection

Ask about any prescription or over-the-counter medication and we check it for interactions with Pleurisy Root 450 mg by TerraVita Premium Collection — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Pleurisy Root 450 mg by TerraVita Premium Collection

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: pleurisy root (asclepias tuberosa) at 450 mg per capsule. Pleurisy root is a plant traditionally used in herbal medicine, though it's not FDA-approved for any specific condition.

The capsule itself is made from gelatin and water, which are inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Pleurisy Root product and its label doesn't state a use — see Pleurisy Root's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We hold no effectiveness ratings for pleurisy root in our data. That means the evidence for what it does—or how well it works—isn't established in the information we have on file.

The evidence, ingredient by ingredient Pleurisy Root

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pleurisy root has a significant safety caution: it contains potentially toxic compounds and carries very little safety data, so if you're considering it, use it only under the guidance of your doctor or pharmacist. The safety data advises against use during pregnancy because it's traditionally been used to stimulate uterine contractions.

For breastfeeding, the safety rating is "Possibly Unsafe"—there isn't enough data to know for sure, so talk with your doctor or pharmacist before using it while nursing. Side effects from pleurisy root include stomach upset, nausea, and vomiting.

In larger amounts, it can trigger digitalis-like poisoning symptoms—a cluster that includes slow pulse, heart rhythm abnormalities, blurred vision, dizziness, muscle weakness, tremors, confusion, and in severe cases, cardiovascular collapse. Topical use may cause skin irritation.

Side effects, ingredient by ingredient Pleurisy Root

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Pleurisy Root.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: heart-rhythm medications.
  • For scale: 117 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check with your doctor or pharmacist before starting if you take digoxin (Lanoxin) or any other heart drugs, water pills (especially furosemide, hydrochlorothiazide, or chlorthalidone), or estrogen-based medications like birth control or hormone therapy. These interactions are documented and range from Major to Moderate in severity.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Pleurisy root is a traditional herb with serious interaction risks—especially if you take heart medications, water pills, or birth control. The safety data is sparse and it carries caution for use in pregnancy and breastfeeding.

Before you take it, check your medications with your doctor or pharmacist, since the interactions are real and potentially serious.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 21, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pleurisy Root 450 mg, straight from the product label.

Brand TerraVita Premium Collection
Barcode (UPC) 064435115340
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Feb 21, 2023
DSLD ID 286540
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pleurisy Root 450 mg by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
100
UPC/BARCODE
064435115340
IngredientAmount% DV
Pleurisy Root450 mg--

Other ingredients: Gelatin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Brand IP Statement(s)

Copyright 2004 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Suggested/Recommended/Usage/Directions

Directions Take 1 capsule, 3 times daily, with meals.

General Statements

TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.

Please recycle!

FDA Disclaimer Statement

Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pleurisy Root 450 mg by TerraVita Premium Collection label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pleurisy Root 450 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pleurisy Root 450 mg by TerraVita Premium Collection

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Pleurisy Root

Interacts with
117 drugs
450 mg per serving

Pleurisy root is the dried root of Asclepias tuberosa (butterfly weed), a plant used in traditional North American and herbal medicine mainly for resp...

Pleurisy Root monograph & interactions

Other (inactive) ingredients: Gelatin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pleurisy Root 450 mg by TerraVita Premium Collection Drug Interactions

Want to check YOUR meds against Pleurisy Root 450 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
117Drugs
1 Major 116 Moderate

Ingredients driving the most interactions

Pleurisy Root 117

Individual Drug Interactions

The ingredients in Pleurisy Root 450 mg interact with 117 drugs. Click any drug to see the details.

1 of the 1 ingredient in Pleurisy Root 450 mg interact with drugs. Each result below shows which ingredient is responsible. Pleurisy Root

Each ingredient & the kinds of drugs it affects

For each ingredient in Pleurisy Root 450 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Pleurisy Root3 drug types · 117 drugs

Digoxin (Lanoxin)

Pleurisy root contains digitalis-like cardenolide glycosides. Taking pleurisy root in combination with digoxin could increase the risk of adverse effects and toxicity.

Likelihood Probable Evidence D
Diuretic Drugs

Theoretically, concomitant use of potassium-depleting diuretics and pleurisy root can increase the risk of cardiac glycoside toxicity due to potassium depletion. Some diuretics that can deplete potassium include chlorothiazide (Diuril), chlorthalidone (Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, Hydrodiuril, Microzide), and others.

Likelihood Possible Evidence D
Estrogens

Theoretically, excessive amounts of pleurisy root might interfere with hormone drug therapy.

Likelihood Possible Evidence D
Pleurisy Root full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pleurisy Root 450 mg, from the product label.

TerraVita Premium Collection

See all TerraVita Premium Collection products
Name
TerraVita Fine Whole Herbs
City
Brampton
State
Ontario
Pharmacist Counseling Corner

Pleurisy Root 450 mg by TerraVita Premium Collection: Common Questions

Does Pleurisy Root 450 mg by TerraVita Premium Collection interact with any medications?
Yes. Based on its ingredients, Pleurisy Root 450 mg has a known interaction with 117 medications, including 1 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pleurisy Root 450 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take pleurisy root if I'm pregnant?
No. The safety data advises against it because pleurisy root has been traditionally used to stimulate the uterus and is considered unsafe in pregnancy. Talk with your doctor or pharmacist before taking it if you're pregnant or trying to conceive.
Is it safe to breastfeed while taking pleurisy root?
The safety rating for breastfeeding is "Possibly Unsafe"—meaning there isn't enough data to know either way. Talk with your doctor or pharmacist to decide whether it's right for you while nursing.
What side effects might I get from pleurisy root?
The most common side effects are stomach irritation, nausea, and vomiting. In larger doses, it can cause digitalis-like poisoning symptoms, including a slow pulse, heart rhythm problems, blurred vision, dizziness, muscle weakness, tremors, confusion, and in severe cases, cardiovascular shock.
Does pleurisy root have a lot of safety data behind it?
No—it has very little safety data and contains potentially toxic compounds. The caution is to use it only under the guidance of your doctor or pharmacist.
Can I use pleurisy root if I take a water pill for blood pressure?
You should check with your doctor or pharmacist first. Water pills that lower potassium (like furosemide, hydrochlorothiazide, or chlorthalidone) combined with pleurisy root can raise the risk of heart problems because the root's digitalis-like compounds become more dangerous when potassium is low.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pleurisy Root 450 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pleurisy Root 450 mg label
Go deeper

The Full Monographs Behind Pleurisy Root 450 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Pleurisy Root

Interacts with 117 drugs

Pleurisy root is the dried root of Asclepias tuberosa (butterfly weed), a plant used in traditional North American and herbal medicine mainly for respiratory complaints. There is very little...

Read the full Pleurisy Root monograph →
Sources

Sources & How We Checked

Pleurisy Root 450 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pleurisy Root 7 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  5. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  6. Gossel TA, Bricker JD. Principles of Clinical Toxicology. New York, NY:Raven Press, 1994.
  7. De Smet PAGM, Keller K, Hansel R, Chandler RF, Eds. Adverse Effects of Herbal Drugs 1. Verlag, Berlin: Springer, 1992. DOI

See these in context on the Pleurisy Root monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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