Interactions on record — worth a quick check against your medications. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

PMA Positive Mental Attitude Ingredients & Drug Interactions

by Viva Vitamins

Capsule Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

PMA Positive Mental Attitude is a dietary supplement by Viva Vitamins with 4 active ingredients. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 440 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are GABA, L-Glutamine, L-Tyrosine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of PMA Positive Mental Attitude by Viva Vitamins

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

PMA Positive Mental Attitude contains 4 active ingredients: L-glutamine, GABA (gamma-aminobutyric acid), L-tyrosine, and DL-phenylalanine. L-glutamine is an amino acid that supports recovery and immune function.

GABA is a neurotransmitter involved in relaxation and nerve signaling. L-tyrosine is another amino acid that serves as a building block for neurotransmitters and thyroid hormones.

DL-phenylalanine is an amino acid compound. The capsule itself is made from vegetable material.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: mental alertness, focus, mood and motivation support.
  • We looked for evidence on: Anxiety, Attention deficit-hyperactivity disorder (ADHD), Cognitive function, Depression, Fatigue, Insomnia — and 4 related terms.
  • The strongest evidence on file: Tyrosine is rated "Possibly Effective" for Cognitive function (Natural Medicines).
  • Also on file: Tyrosine is rated "Possibly Effective" for Memory.
  • Also on file: Gamma-aminobutyric Acid (gaba) is rated "Insufficient Reliable Evidence To Rate" for Anxiety, Attention deficit-hyperactivity disorder (ADHD), Depression, Insomnia, and more.

Evidence for this product's effectiveness is limited and mixed. L-tyrosine is possibly effective for cognitive function and memory, and effective for the rare metabolic condition phenylketonuria (PKU).

The other ingredients have insufficient reliable evidence to rate them for mental attitude or mood support — meaning the science hasn't established whether they work for those purposes in the way this product markets them. GABA, for example, shows insufficient evidence for anxiety, despite common claims about its calming role in the brain.

The evidence, ingredient by ingredient Glutamine Gamma-aminobutyric Acid (gaba) Tyrosine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-glutamine is rated likely safe in pregnancy and lactation. However, all four ingredients carry cautions about long-term safety — the data is incomplete.

L-glutamine and L-tyrosine are generally well tolerated in healthy adults, though people with kidney or liver disease should use L-glutamine only under medical supervision. GABA and L-tyrosine aren't recommended during breastfeeding because there isn't enough safety information.

Common side effects across the ingredients include headache, nausea, and gastrointestinal upset like bloating, constipation, or diarrhea. At higher doses, L-glutamine has been linked to dizziness and, rarely, mania in people with bipolar disorder.

GABA may cause drowsiness or muscle weakness.

Side effects, ingredient by ingredient Glutamine Gamma-aminobutyric Acid (gaba) Tyrosine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Gamma-aminobutyric Acid (gaba), Glutamine, Tyrosine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications; Parkinson's medications.
  • For scale: 440 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this product if you're on any of the following: seizure medications (anticonvulsants), blood pressure medications (antihypertensives), levodopa for Parkinson's disease, thyroid hormones, sedatives or sleep aids (CNS depressants), or any psychiatric medications. These are the medication types documented to interact with ingredients in this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you take seizure medications, blood pressure medications, Parkinson's medication (levodopa), or thyroid hormones, you'll want to talk with your doctor or pharmacist before starting this product. Even if you don't take those specific drugs, the interaction data is substantial — check your full medication list with the tool on this page.

L-glutamine and L-tyrosine are generally well tolerated, but long-term safety for all four ingredients isn't well established, and evidence that they improve mood or mental attitude is lacking.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 26, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about PMA Positive Mental Attitude, straight from the product label.

Brand Viva Vitamins
Barcode (UPC) 812720016335
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Dec 26, 2020
DSLD ID 238867
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for PMA Positive Mental Attitude by Viva Vitamins, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
812720016335
IngredientAmount% DV
L-Glutamine100 mg--
GABA100 mg--
L-Tyrosine200 mg--
DL-Phenylalanine250 mg--

Other ingredients: Vegetable Capsules

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Direction: As a dietary supplement, take one or more capsules daily, on an empty stomach, or as directed by your health care practitioner.

Formulation

Viva's PMA assists in the maintenance of mental alertness and acuity, while helping to promote motivation, a positive mood, and the ability to focus. The neurotransmitters in our bodies are produced from amino acid building blocks, primarily L-Tyrosine and DL-Phenylalanine. Viva has combined these amino acids with L-glutamine and GABA to help foster proper brain function and mental activity. So be positive with Viva's PMA.

Promotes mental performance Assists feelings of well-being

Contains No: Sugar, salt, starch, yeast, corn, soy, wheat, lactose, citrus, gluten, milk, egg, fish products, artificial coloring, flavoring, or preservatives.

Made in the USA

Non-GMO

Manufactured in an NSF - GMP Certified facility

Precautions

Keep out of the reach of children.

Do not use if safety seal under cap is broken or missing.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

We care about your family's health Specialty formulas

We always use the freshest food-derived ingredients Premium formulas

For more information, visit www.vivavitamins.com

In God we trust

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

2017 Manufactured exclusively for Viva Vitamins

See for yourself

PMA Positive Mental Attitude by Viva Vitamins label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in PMA Positive Mental Attitude by Viva Vitamins

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Glutamine

Interacts with
50 drugs
100 mg per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions

GABA

Interacts with
419 drugs
100 mg per serving

GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep...

GABA monograph & interactions

L-Tyrosine

Interacts with
21 drugs
200 mg per serving

L-tyrosine is an amino acid your body uses to make brain chemicals like dopamine and norepinephrine. Some studies suggest it may help mental performan...

L-Tyrosine monograph & interactions

DL-Phenylalanine

250 mg per serving

Other (inactive) ingredients: Vegetable Capsules. These complete the product’s ingredient list but are not active constituents.

Interaction report

PMA Positive Mental Attitude by Viva Vitamins Drug Interactions

Want to check YOUR meds against PMA Positive Mental Attitude?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
440Drugs
242 Moderate 198 Minor

Ingredients driving the most interactions

GABA 419

Each ingredient & the kinds of drugs it affects

For each ingredient in PMA Positive Mental Attitude with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

GABA2 drug types · 419 drugs

Antihypertensive Drugs

Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Some clinical research shows that GABA can decrease blood pressure in patients with hypertension.

Likelihood Possible Evidence B
Cns Depressants

Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants. However, it is unclear if this concern is clinically relevant.
Endogenous GABA has well-established relaxant effects and GABA(A) receptors have an established physiological role in sleep. However, the effects of GABA supplements are unclear, as it is unknown whether exogenous GABA crosses the blood-brain barrier. Although there have been limited reports of drowsiness or tiredness with GABA supplements, these effects have not been widely reported in clinical studies. Additionally, intravenous GABA 0.1-1 mg/kg has been shown to induce anxiety in a dose-dependent manner.

Likelihood Unlikely Evidence D

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D

L-Tyrosine2 drug types · 21 drugs

Levodopa

Theoretically, tyrosine might decrease the effectiveness of levodopa.
Tyrosine and levodopa compete for absorption in the proximal duodenum by the large neutral amino acid (LNAA) transport system. Advise patients to separate doses of tyrosine and levodopa by at least 2 hours.

Likelihood Probable Evidence D
Thyroid Hormone

Theoretically, tyrosine might have additive effects with thyroid hormone medications.
Tyrosine is a precursor to thyroxine and might increase levels of thyroid hormones.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for PMA Positive Mental Attitude, from the product label.

Viva Vitamins

Name
Viva Vitamins
Street Address
25908 McBean Pkwy
City
Valencia
State
CA
ZipCode
91355
Web Address
www.vivavitamins.com
Pharmacist Counseling Corner

PMA Positive Mental Attitude by Viva Vitamins: Common Questions

Does PMA Positive Mental Attitude by Viva Vitamins interact with any medications?
Yes. Based on its ingredients, PMA Positive Mental Attitude has a known interaction with 440 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
PMA Positive Mental Attitude contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is L-glutamine safe if I have kidney or liver problems?
L-glutamine is generally well tolerated, but if you have kidney or liver disease, it should only be used under medical supervision. Talk to your doctor before taking this product.
Can I take this while breastfeeding?
There isn't enough safety information for GABA or L-tyrosine during breastfeeding, and the product label advises caution. L-glutamine is rated likely safe, but the overall product carries a caution. Discuss it with your doctor or pharmacist before starting.
What are the most common side effects?
The most common side effects reported across the ingredients are headache, nausea, and gastrointestinal issues like bloating, constipation, and diarrhea. At higher doses, you might experience dizziness or drowsiness.
Does this product actually improve mood or mental attitude?
The evidence for that isn't established in the data we hold. GABA, in particular, shows insufficient evidence for anxiety despite its role in the nervous system. L-tyrosine is possibly effective for memory and cognitive function, but the product as a whole hasn't been proven for mood support.
Is there a risk of mania or mood disturbance?
Mania and hypomania have been reported in two patients with bipolar disorder taking glutamine at high doses. If you have bipolar disorder, mention this product to your doctor before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if PMA Positive Mental Attitude is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

PMA Positive Mental Attitude label
Sources

Sources & How We Checked

PMA Positive Mental Attitude's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 27 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Gamma-aminobutyric Acid (gaba) 12 references
  1. Cavagnini F, Invitti C, Pinto M, et al. Effect of acute and repeated administration of gamma aminobutyric acid (GABA) on growth hormone and prolactin secretion in man. Acta Endocrinol (Copenh) 1980;93:149-54.
  2. Nurnberger JI Jr, Berrettini WH, Simmons-Alling S, et al. Intravenous GABA administration is anxiogenic in man. Psychiatry Res 1986;19:113-7. PubMed
  3. Gershman RN, Vasilenko MA, Iliushina GG, et al. [Gammalon in the rehabilitation in infantile cerebral palsy]. Pediatr.Akus.Ginekol. 1977;(6):26-7.
  4. Loeb C, Benassi E, Bo, GP, et al. Preliminary evaluation of the effect of GABA and phosphatidylserine in epileptic patients. Epilepsy Res. 1987;1:209-12 . PubMed
  5. Inoue K, Shirai T, Ochiai H, et al. Blood-pressure-lowering effect of a novel fermented milk containing gamma-aminobutyric acid (GABA) in mild hypertensives. Eur J Clin Nutr 2003;57:490-95.
  6. ELLIOTT, K. A. and JASPER, H. H. Gammaaminobutyric acid. Physiol Rev. 1959;39(2):383-406.
  7. Winsky-Sommerer, R. Role of GABAA receptors in the physiology and pharmacology of sleep. Eur.J.Neurosci. 2009;29(9):1779-1794.
  8. Meldrum, B. S. GABAergic mechanisms in the pathogenesis and treatment of epilepsy. Br.J.Clin.Pharmacol. 1989;27 Suppl 1:3S-11S. PubMed
  9. Loeb, C., Marinari, U. M., Benassi, E., Besio, G., Cottalasso, D., Cupello, A., Maffini, M., Mainardi, P., Pronzato, M. A., and Scotto, P. A. Phosphatidylserine increases in vivo the synaptosomal uptake of exogenous GABA in rats. Exp.Neurol. 1988;99(2):4 PubMed
  10. Melis, G. B., Paoletti, A. M., Mais, V., and Fioretti, P. Interference of dopamine infusion on gamma-amino butyric acid (GABA)-stimulated prolactin increase. J.Endocrinol.Invest 1980;3(4):445-448.
  11. Boonstra E, de Kleijn R, Colzato LS, Alkemade A, Forstmann BU, Nieuwenhuis S. Neurotransmitters as food supplements: the effects of GABA on brain and behavior. Front Psychol. 2015 Oct 6;6:1520. doi: 10.3389/fpsyg.2015.01520. eCollection 2015. PubMed
  12. de Bie TH, Witkamp RF, Balvers MG, Jongsma MA. Effects of ?-aminobutyric acid supplementation on glucose control in adults with prediabetes: A double-blind, randomized, placebo-controlled trial. Am J Clin Nutr 2023;118(3):708-719. PubMed

See these in context on the Gamma-aminobutyric Acid (gaba) monograph →

Tyrosine 4 references
  1. Meyer JS, Welch KM, Deshmukh VD, et al. Neurotransmitter precursor amino acids in the treatment of multi-infarct dementia and Alzheimer's disease. J Amer Geriat Soc 1977;25:289-98.
  2. DiPiro JT, Talbert RL, Yee GC, et al; eds. Pharmacotherapy: A pathophysiologic approach. 4th ed. Stamford, CT: Appleton & Lange, 1999.
  3. Wood DR, Reimherr FW, Wender PH. Amino acid precursors for the treatment of attention deficit disorder, residual type. Psychopharmacol Bull 1985;21:146-9.
  4. van Spronsen FJ, van Rijn M, Bekhof J. Phenylketonuria: tyrosine supplementation in phenylalanine-restricted diets. Am J Clin Nutr 2001;73:153-7. PubMed

See these in context on the Tyrosine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring