ABC White Appletini Ingredients & Drug Interactions
What is this page for?
First and foremost: checking ABC White Appletini against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
ABC White Appletini is a dietary supplement by Core Nutritionals with 6 active ingredients. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against ABC White Appletini by Core Nutritionals
Ask about any prescription or over-the-counter medication and we check it for interactions with ABC White Appletini by Core Nutritionals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of ABC White Appletini by Core Nutritionals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
ABC White Appletini has 6 active ingredients — branched-chain amino acids (L-Leucine, L-Isoleucine, and L-Valine), L-Glutamine, CarnoSyn (beta-alanine), and Citrulline Malate. These are amino acids and amino-acid-like compounds often used in fitness supplements to support muscle recovery and exercise performance.
The powder also contains inactive ingredients — natural and artificial flavors, citric acid, sucralose, and acesulfame-K — which are fillers and flavoring agents common in supplement powders.
Does it work?
Moderate evidence
L-Glutamine is rated Effective for sickle cell disease and Possibly Effective for HIV/AIDS-related wasting, postoperative recovery, and critical illness from trauma. CarnoSyn (beta-alanine) is rated Possibly Effective for athletic and physical performance.
We don't have established evidence in our data for the other amino acids in this blend, and beta-alanine's effectiveness for cognitive decline, COPD, cognitive function, or menopausal symptoms hasn't been reliably demonstrated.
How safe is it?
Well-documented data
L-Glutamine is generally well tolerated orally, though it commonly causes gastrointestinal side effects like bloating, nausea, diarrhea, and constipation — especially at high doses. Headache and dizziness have been reported, and rare cases of mood changes (mania) occurred in people with bipolar disorder.
If you have kidney or liver disease, you should only use this under your doctor's supervision. CarnoSyn (beta-alanine) is generally well tolerated but commonly causes harmless tingling and flushing of the skin, usually starting on the scalp within 20 minutes and lasting about an hour.
It's not well studied for long-term high-dose use. The safety data advises against using this product during pregnancy or while breastfeeding.
L-Glutamine is rated Likely Safe in pregnancy and lactation, but there isn't enough data on the other ingredients to know either way — talk with your doctor or pharmacist about your specific situation.
Meds to double-check
Moderate interaction found
Anticonvulsant medications (seizure drugs) are the key one to double-check before starting this product — L-Glutamine may theoretically interfere with how they work. Run your exact medication through the checker on this page to be sure.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This is a branched-chain amino acid supplement that may help with muscle recovery and athletic performance, with L-Glutamine also having established use for sickle cell disease. If you take anticonvulsant (seizure) medication, you'll want to check with us first — that's the main drug concern.
Expect some skin tingling from the beta-alanine and possible digestive side effects from the glutamine. Talk to your pharmacist about whether it fits your health picture and medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2017.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about ABC White Appletini, straight from the product label.
| Brand | Core Nutritionals |
|---|---|
| Barcode (UPC) | 850757001429 |
| Net contents | 2.1875 lbs; 1 kg |
| Market status | On market |
| Date entered into DSLD | May 24, 2017 |
| DSLD ID | 73947 |
| Product type | Other Combinations |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for ABC White Appletini by Core Nutritionals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L-Glutamine | 2.5 Gram(s) | -- |
| L-Leucine | 5 Gram(s) | -- |
| L-Isoleucine | 2.5 Gram(s) | -- |
| L-Valine | 2.5 Gram(s) | -- |
| CarnoSyn | 2.5 Gram(s) | -- |
| Branched-Chain Amino Acids | 0 NP | -- |
| Citrulline Malate | 2.5 Gram(s) | -- |
Other ingredients: Natural and Artificial flavors, Citric Acid, Sucralose, Acesulfame-K
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Making a great BCAA product may be complicated, and other companies may get it wrong, but Core Nutritionals makes a superior BCAA product elementary. Tested amino ratios. Proven formulas. No unnecessary fillers.
A: Aminos in the only clinically-verified and tested BCAA (branched chain amino acid) ratio of 2:1:1 to support endurance, recovery, and the building of lean muscle.
C: Citrulline malate, at a clinical serving size, that may help to increase NO (nitric oxide) synthesis and ATP production.
When combined with regular weight/resistance training and a healthy, balanced diet.
Superior recovery and endurance
100 scoops BCAAS
Manufactured in a U.S. CGMP facility.
Brand IP Statement(s)
B: Beta-Alanine as CarnoSyn , the only patented brand of beta-alanine. CarnoSyn has been shown to increase muscle strength and performance, increase endurance, and decrease muscular fatigue.
Crush It
CarnoSyn Carnosine Synthesizer
Natural Alternatives International (NAI) is the owner of patents as listed on www.carnosyn.com and registered trademark CarnoSyn.
Precautions
Warning: This product is only intended for use in healthy adults 18 years of age or older.
Pregnant or nursing women should not use this product. Consult your healthcare provider before using this product, especially if you are taking any prescription, over the counter medication, dietary supplement product, or if you have any pre-existing medical condition including but not limited to: high or low blood pressure, cardiac arrhythmia, stroke, heart, liver, kidney or thyroid disease, seizure disorder, psychiatric disease, diabetes, difficulty urinating due to prostate enlargement or if you are taking a MAOI (Monoamine Oxidase Inhibitor) or any other medication.
Consult your healthcare provider before using this product, especially if you are taking any prescription, over the counter medication, dietary supplement product, or if you have any pre-existing medical condition including but not limited to: high or low blood pressure, cardiac arrhythmia, stroke, heart, liver, kidney or thyroid disease, seizure disorder, psychiatric disease, diabetes, difficulty urinating due to prostate enlargement or if you are taking a MAOI (Monoamine Oxidase Inhibitor) or any other medication. Immediately discontinue use and consult your health care professional if you experience adverse reaction to this product. Do not exceed recommended serving. Do not use if safety seal is broken or missing.
Keep out of reach of children.
Suggested/Recommended/Usage/Directions
Directions: Mix 2 scoops in 16-32 ounces of water and shake well. Adjust water level according to taste. Consume immediately before and during training. Additional servings can be taken throughout the day to maximize effectiveness.
FDA Statement of Identity
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Dietary Supplement
Formula
Amino acids. Beta-Alanine. Citrulline malate
Formulation
No fillers No sugars No artificial colors No calories Caffeine free Gluten free
Storage
Protect from heat, light and moisture Store at 10-25(0)C (50-77(0)F)
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
ABC White Appletini by Core Nutritionals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in ABC White Appletini by Core Nutritionals
These are the 6 active ingredients this product is made of. Select any to open its full monograph.
Serving size20 Gram(s) Dosage formPowder Servings per container50 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
L-Glutamine
Interacts with50 drugs
Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...
L-Glutamine monograph & interactionsCarnoSyn
No knowninteractions
Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-int...
CarnoSyn monograph & interactionsBranched-Chain Amino Acids
- › L-Leucine
- › L-Isoleucine
- › L-Valine
Citrulline Malate
Other (inactive) ingredients: Natural and Artificial flavors, Citric Acid, Sucralose, Acesulfame-K. These complete the product’s ingredient list but are not active constituents.
ABC White Appletini by Core Nutritionals Drug Interactions
HelloPharmacist Interaction Report
ABC White Appletini by Core Nutritionals contains L-Glutamine, which has documented interactions with medications.
The main concern is with anticonvulsant drugs (seizure medications). Glutamine is broken down in your body to glutamate, an excitatory brain chemical that may theoretically work against how anticonvulsants function — though this hasn't yet been reported in actual patients.
Read the full breakdown — every affected drug type, severity by severity
Altogether, these interactions span 50 individual medications.
We couldn't check three other ingredients in this product — L-Leucine, L-Isoleucine, and Citrulline Malate — because we hold no interaction data for them. CarnoSyn (beta-alanine) showed no interactions in our database.
If you take anticonvulsant medication, run your exact drug through the checker on this page before you start, and let your pharmacist know you're considering this supplement.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against ABC White Appletini?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in ABC White Appletini interact with 50 drugs. Click any drug to see the details.
1 of the 6 ingredients in ABC White Appletini interact with drugs. Each result below shows which ingredient is responsible. L-Glutamine
AcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Acetazolamide interactionAminophylline, Amobarbital, EphedrineAmesec
How Aminophylline, Amobarbital, Ephedrine interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Aminophylline, Amobarbital, Ephedrine interactionAmobarbitalAmytal
How Amobarbital interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Amobarbital interactionAmobarbital, Ephedrine SulfateEphedrine & Amytal
How Amobarbital, Ephedrine Sulfate interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Amobarbital, Ephedrine Sulfate interactionAmobarbital, SecobarbitalTuinal
How Amobarbital, Secobarbital interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Amobarbital, Secobarbital interactionAprobarbital, Butabarbital, PhenobarbitalTriple Barbital
How Aprobarbital, Butabarbital, Phenobarbital interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Aprobarbital, Butabarbital, Phenobarbital interactionBelladonna, Caffeine, Ergotamine, PentobarbitalMicomp PB
How Belladonna, Caffeine, Ergotamine, Pentobarbital interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Belladonna, Caffeine, Ergotamine, Pentobarbital interactionBelladonna, PhenobarbitalBellophen, Susano
How Belladonna, Phenobarbital interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Belladonna, Phenobarbital interactionBellafoline, Caffeine, Ergotamine Tartrate, PentobarbitalCafergot PB
How Bellafoline, Caffeine, Ergotamine Tartrate, Pentobarbital interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Bellafoline, Caffeine, Ergotamine Tartrate, Pentobarbital interactionButalbital, Phenobarbital, SecobarbitalTribarb
How Butalbital, Phenobarbital, Secobarbital interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Butalbital, Phenobarbital, Secobarbital interactionCarbamazepineCarbatrol, Carnexiv, Equetro, Tegretol, Tegretol XR
How Carbamazepine interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Carbamazepine interactionCenobamateXcopri
How Cenobamate interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Cenobamate interactionClobazamFrisium, Onfi, Sympazan
How Clobazam interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Clobazam interactionClonazepamCeberclon, Klonopin, Rivotril
How Clonazepam interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Clonazepam interactionClorazepateTranxene, Tranxene SD, Tranxene T-Tab
How Clorazepate interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Clorazepate interactionDiazepamDiastat AcuDial, Valium, Valium injection, Valtoco
How Diazepam interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Diazepam interactionDivalproex SodiumDepakote
How Divalproex Sodium interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Divalproex Sodium interactionEphedrine, Phenobarbital, TheophyllineTedral
How Ephedrine, Phenobarbital, Theophylline interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Ephedrine, Phenobarbital, Theophylline interactionEthosuximideZarontin
How Ethosuximide interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Ethosuximide interactionEthotoinPaganone
How Ethotoin interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Ethotoin interactionFelbamateFelbatol
How Felbamate interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Felbamate interactionFosphenytoinCerebyx
How Fosphenytoin interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Fosphenytoin interactionFosphenytoin SodiumSesquient
How Fosphenytoin Sodium interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Fosphenytoin Sodium interactionGabapentinGralise, Neurontin
How Gabapentin interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Gabapentin interactionGabapentin EnacarbilHorizant
How Gabapentin Enacarbil interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Gabapentin Enacarbil interactionLamotrigineLamictal
How Lamotrigine interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Lamotrigine interactionLevetiracetamElepsia XR, Keppra, Spritam
How Levetiracetam interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Levetiracetam interactionLorazepamAtivan
How Lorazepam interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Lorazepam interactionMagnesium Sulfate (prescription Drug)Bilagog, Magnesium Sulfate
How Magnesium Sulfate (prescription Drug) interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Magnesium Sulfate (prescription Drug) interactionMephenytoinMesantoin
How Mephenytoin interacts with ABC White Appletini — through 1 ingredient. Tap an ingredient for the detail:
L-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Mephenytoin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in ABC White Appletini with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
L-Glutamine
Anticonvulsants
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.
Brand information
Manufacturer and brand details for ABC White Appletini, from the product label.
Core Nutritionals
See all Core Nutritionals products- Name
- Core Nutritionals, LLC
- City
- Arlington
- State
- Virginia
- Phone Number
- (888) 978-2332
- Web Address
- www.CoreNutritionals.com
ABC White Appletini by Core Nutritionals: Common Questions
Does ABC White Appletini by Core Nutritionals interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this make me tingle or have side effects?
Is it safe to use while pregnant or breastfeeding?
What does glutamine actually do?
What's CarnoSyn and why is it in here?
Should I worry about the sweeteners?
Can I use this if I have kidney or liver problems?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if ABC White Appletini is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind ABC White Appletini’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Glutamine
Interacts with 50 drugsGlutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...
Read the full Glutamine monograph → Herb & supplement monographBeta-alanine
Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-intensity exercise. The evidence is moderat...
Read the full Beta-alanine monograph →Sources & How We Checked
ABC White Appletini's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 24 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Glutamine 11 references
- Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
- Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
- Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
- Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
- Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
- Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
- Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
- Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
- Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
- Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
- Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed
Beta-alanine 13 references
- Harris RC, Tallon MJ, Dunnett M, et al. The absorption of orally supplied beta-alanine and its effect on muscle carnosine synthesis in human vastus lateralis. Amino Acids 2006;30:279-89.
- Hill CA, Harris RC, Kim HJ, et al. Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity. Amino Acids 2007;32:225-33.
- Bellinger PM, Minahan CL. The effect of ß-alanine supplementation on cycling time trials of different length. Eur J Sport Sci 2016;16(7):829-36.
- Chung W, Shaw G, Anderson ME, et al. Effect of 10 week beta-alanine supplementation on competition and training performance in elite swimmers. Nutrients 2012;4(10):1441-53. PubMed
- Glenn JM, Gray M, Stewart R, et al. Incremental effects of 28 days of beta-alanine supplementation on high-intensity cycling performance and blood lactate in masters female cyclists. Amino Acids 2015;47(12):2593-600. PubMed
- Gross M, Bieri K, Hoppeler H, Norman B, Vogt M. Beta-alanine supplementation improves jumping power and affects severe-intensity performance in professional alpine skiers. Int J Sport Nutr Exerc Metab 2014;24(6):665-73. PubMed
- Howe ST, Bellinger PM, Driller MW, Shing CM, Fell JW. The effect of beta-alanine supplementation on isokinetic force and cycling performance in highly trained cyclists. Int J Sport Nutr Exerc Metab 2013;23(6):562-70. PubMed
- Sweeney KM, Wright GA, Glenn Brice A, Doberstein ST. The effect of beta-alanine supplementation on power performance during repeated sprint activity. J Strength Cond Res 2010;24(1):79-87.
- Décombaz J, Beaumont M, Vuichoud J, Bouisset F, Stellingwerff T. Effect of slow-release ß-alanine tablets on absorption kinetics and paresthesia. Amino Acids 2012;43(1):67-76. Erratum in: Amino Acids 2013;45(4):1015.
- Stellingwerff T, Anwander H, Egger A, et al. Effect of two ß-alanine dosing protocols on muscle carnosine synthesis and washout. Amino Acids 2012;42(6):2461-72. PubMed
- da Silva RP, de Oliveira LF, Saunders B, et al. Effects of ß-alanine and sodium bicarbonate supplementation on the estimated energy system contribution during high-intensity intermittent exercise. Amino Acids. 2019;51(1):83-96. PubMed
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