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Dietary supplement

Potassium Chloride Powder Ingredients & Drug Interactions

by NOW

Potassium Chloride Powder label
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Powder Category: Mineral
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Potassium Chloride Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Potassium Chloride Powder is a dietary supplement by NOW with 1 active ingredient. Its ingredients are commonly taken for preventing or treating low potassium (hypokalemia), supporting healthy blood pressure, muscle cramps.Based on those ingredients, 62 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Potassium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Potassium Chloride Powder by NOW

Ask about any prescription or over-the-counter medication and we check it for interactions with Potassium Chloride Powder by NOW — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Potassium Chloride Powder by NOW

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Potassium” is listed as a grouped ingredient — the label gives one combined amount (363 mg) without saying how much of each component you get.

This is a single-ingredient supplement: potassium chloride, a common form of potassium. The one active ingredient is potassium itself.

Magnesium carbonate is listed as an inactive ingredient (a filler or binder used in the powder).

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: potassium supplementation for electrolyte balance.
  • We looked for evidence on: hypokalemia, electrolyte balance, muscle function.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The product facts we hold do not include effectiveness ratings for potassium chloride. We cannot tell you from our data whether it works for any particular purpose.

The evidence, ingredient by ingredient Potassium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Potassium from food is safe and necessary. Potassium supplements are a different story — they can cause dangerously high blood levels in some people, especially those with kidney disease.

That's why you need medical guidance before taking them. Common side effects from oral potassium include abdominal pain, belching, diarrhea, nausea, and vomiting.

Rare but serious effects from high blood potassium are heart rhythm problems, low blood pressure, and mental confusion. During pregnancy, dietary potassium is appropriate, but use supplements only under medical guidance.

The same applies to breastfeeding — check with your doctor first.

Side effects, ingredient by ingredient Potassium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Potassium.
  • The most serious interaction on file is rated Moderate.
  • For scale: 62 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Do not take this product with potassium-sparing diuretics, ACE inhibitors, or angiotensin receptor blockers (ARBs) without your doctor's approval — all three increase the risk of dangerously high blood potassium. Use the search tool on this page to check your exact medications before you buy.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Potassium supplements are not casual vitamins. They're useful for people with genuine deficiency, but only under a doctor's supervision.

If you take a blood pressure medication or water pill, you must talk to your pharmacist or doctor before starting this product. Even if you don't take prescription drugs, kidney function matters — get professional guidance.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Potassium Chloride Powder, straight from the product label.

Brand NOW
Barcode (UPC) 733739014504
Net contents 8 Ounce(s); 227 Gram(s)
Market status On market
Date entered into DSLD Sep 25, 2025
DSLD ID 335292
Product type Mineral
Supplement form Powder
Dietary claims / uses Nutrient, All Other
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Potassium Chloride Powder by NOW, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 Gram(s)
Maximum serving Sizes:
0.7 Gram(s)
Servings per container
324
UPC/BARCODE
733739014504
IngredientAmount% DV
Potassium363 mg8%
Potassium Chloride693 mg--

Other ingredients: Magnesium Carbonate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Usage: Take 1/8 teaspoon with food. Take with at least 8 oz. of water or other beverage. Can be taken 1 to 3 times daily in separate servings.

Precautions

Do not exceed 3 servings per day.

Caution: For adults only.

Consult physician if pregnant/nursing, taking any medications (especially those that may affect kidney function or blood potassium levels), or have a medical condition (especially heart/kidney condition or diabetes).

Keep out of reach of children.

Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Formulation

Natural color variation may occur in this product.

Sodium free NON GMO Project Verified nongmoproject.org

Vegetarian/Vegan

Packaged and quality tested in the USA.

Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients.

Storage

This product is sold by weight not volume. Store in a cool, dry place after opening.

General Statements

This bottle is made from 100% PCR (post-consumer recycled) resin.

Minerals Family owned since 1968.

Formula

Essential mineral

Triangle K (Kosher)

Seals/Symbols

NON GMO Project Verified nongmoproject.org Triangle K (Kosher)

GMP Quality Assured

FDA Statement of Identity

A Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Potassium Chloride Powder by NOW label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Potassium Chloride Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Potassium Chloride Powder by NOW

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 Gram(s) Dosage formPowder Servings per container324 Amounts shown are per serving.

Potassium

Interacts with
62 drugs
363 mg per serving

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions

Other (inactive) ingredients: Magnesium Carbonate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Potassium Chloride Powder by NOW Drug Interactions

Want to check YOUR meds against Potassium Chloride Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
62Drugs
62 Moderate

Ingredients driving the most interactions

Potassium 62

Individual Drug Interactions

The ingredients in Potassium Chloride Powder interact with 62 drugs. Click any drug to see the details.

1 of the 1 ingredient in Potassium Chloride Powder interact with drugs. Each result below shows which ingredient is responsible. Potassium

Each ingredient & the kinds of drugs it affects

For each ingredient in Potassium Chloride Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
Potassium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Potassium Chloride Powder, from the product label.

NOW

See all NOW products
Name
NOW Foods
Street Address
395 S. Glen Ellyn Rd.
City
Bloomingdale
State
IL
ZipCode
60108
Web Address
nowfoods.com
Pharmacist Counseling Corner

Potassium Chloride Powder by NOW: Common Questions

Does Potassium Chloride Powder by NOW interact with any medications?
Yes. Based on its ingredients, Potassium Chloride Powder has a known interaction with 62 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Potassium Chloride Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What side effects might I get from taking this?
The most common ones are stomach and digestive: abdominal pain, belching, diarrhea, nausea, and vomiting. Serious side effects from high potassium blood levels — like heart rhythm problems, low blood pressure, or mental confusion — are rare but can happen, especially if your kidneys don't work well.
Is it safe to take while I'm pregnant?
Potassium from your normal diet is fine and necessary. For supplements, the evidence suggests they're likely safe, but use only under medical guidance during pregnancy — this is a conversation to have with your doctor.
Can I take it while breastfeeding?
Dietary potassium is appropriate. For this supplement, check with your doctor first — we recommend personalized advice before you start.
Who really needs a potassium supplement?
The product facts don't tell us that. Generally, potassium from food is how most people meet their needs. A supplement is something to discuss with your doctor — it's not a casual addition to your routine.
Why is this risky with blood pressure pills?
Blood pressure medications like ACE inhibitors and ARBs work partly by reducing how much potassium your kidneys clear. Adding a supplement pushes levels even higher, which can cause serious heart problems. That's why you need your doctor's approval.
What's the magnesium carbonate in here?
That's an inactive ingredient — a filler or binder used in the powder to make it work. It's not an active component.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Potassium Chloride Powder label
Go deeper

The Full Monographs Behind Potassium Chloride Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Potassium

Interacts with 62 drugs

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...

Read the full Potassium monograph →
Sources

Sources & How We Checked

Potassium Chloride Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Potassium 12 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
  3. Whelton PK, He J, Cutler JA, et al. Effects of oral potassium on blood pressure. Meta-analysis of randomized controlled clinical trials. JAMA 1997;277:1624-32. PubMed
  4. Phillips, C. O., Kashani, A., Ko, D. K., Francis, G., and Krumholz, H. M. Adverse effects of combination angiotensin II receptor blockers plus angiotensin-converting enzyme inhibitors for left ventricular dysfunction: a quantitative review of data from ra DOI
  5. Altieri, P. I., Herrero, C., Suero, R., and Ortiz, A. Bleeding duodenal ulcer in a patient taking slow-releasing potassium tablets. Bol.Asoc.Med P.R. 1977;69(8):276.
  6. Raf, L. E. Enteric-coated potassium chloride tablets and ulcer of the small intestine. Acta Chir Scand Suppl 1967;(374):1-87.
  7. Potassium chloride oral solution [package insert]. Allentown, PA: Lehigh Valley Technologies, Inc.; 2014.
  8. Potassium chloride injection [package insert]. Lake Forest, IL: Hospira Inc.; 2009.
  9. Patel RB, Tannenbaum S, Viana-Tejedor A, et al. Serum potassium levels, cardiac arrhythmias, and mortality following non-ST-elevation myocardial infarction or unstable angina: insights from MERLIN-TIMI 36. Eur Heart J Acute Cardiovasc Care 2017 Feb;6(1):1 PubMed
  10. Malta D, Arcand J, Ravindran A, Floras V, Allard JP, Newton GE. Adequate intake of potassium does not cause hyperkalemia in hypertensive individuals taking medications that antagonize the renin angiotensin aldosterone system. Am J Clin Nutr 2016 Oct;104(4 PubMed
  11. Keskin M, Kaya A, Tatlisu MA, et al. The effect of serum potassium level on in-hospital and long-term mortality in ST elevation myocardial infarction. Int J cardiol. 2016 Oct 15;221:505-10.
  12. Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad

See these in context on the Potassium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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