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Dietary supplement

Potassium Gluconate 595 mg Ingredients & Drug Interactions

by up&up

Other (e.g. Tea Bag) Category: Mineral
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Potassium Gluconate 595 mg is a dietary supplement by up&up with 1 active ingredient. Its ingredients are commonly taken for preventing or treating low potassium (hypokalemia), supporting healthy blood pressure, muscle cramps.Based on those ingredients, 62 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Potassium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Potassium Gluconate 595 mg by up&up

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Potassium” is listed as a grouped ingredient — the label gives one combined amount (99 mg) without saying how much of each component you get.

This product contains one active ingredient: potassium from 595 mg of potassium gluconate. Potassium gluconate is a form of potassium that dissolves in the digestive tract.

The product also contains inactive ingredients — stearic acid and magnesium stearate — which are common binders and flow agents in supplements.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: supports fluid balance, muscle and nerve health.
  • We looked for evidence on: hypokalemia, electrolyte balance, muscle function, nerve function.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

We hold no effectiveness data for this product in our records. That doesn't mean it doesn't work for its purpose — potassium is an essential mineral your body needs — but whether a supplement is right for you depends on your individual potassium level and overall health.

Talk with your doctor or pharmacist about whether you actually need supplementation and at what dose.

The evidence, ingredient by ingredient Potassium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Potassium from food is safe and essential. Potassium supplements, though, can be risky.

High blood potassium levels (hyperkalemia) are a real danger, especially if you have kidney disease or take certain medications, and high levels can cause heart rhythm problems, low blood pressure, and confusion. Common side effects from oral potassium are mild — abdominal pain, belching, diarrhea, nausea, and vomiting.

During pregnancy and breastfeeding, dietary potassium is fine, but the safety data advises using supplements only under medical guidance. Check with your doctor before adding any potassium supplement if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Potassium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Potassium.
  • The most serious interaction on file is rated Moderate.
  • For scale: 62 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take potassium-sparing diuretics (water pills that keep potassium in your body), ACE inhibitors, or angiotensin receptor blockers (ARBs) for blood pressure or heart health, check with your doctor or pharmacist before taking this product. All three drug classes raise your blood potassium, and adding a supplement could push levels too high.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Potassium supplements aren't something to take on your own — they need medical oversight because they can raise blood potassium to dangerous levels, especially in people with kidney problems or taking blood pressure medications. If you think you need more potassium, talk with your doctor or pharmacist first.

They can test your level and decide whether diet, a supplement, or neither is the right call for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Potassium Gluconate 595 mg, straight from the product label.

Brand up&up
Barcode (UPC) 070030624835
Net contents 100 Caplet(s)
Market status On market
Date entered into DSLD Jun 25, 2013
DSLD ID 20184
Product type Mineral
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Potassium Gluconate 595 mg by up&up, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Caplet(s)
Maximum serving Sizes:
1 Caplet(s)
UPC/BARCODE
070030624835
IngredientAmount% DV
Potassium99 mg3%
from 595 mg Potassium Gluconate595 mg--

Other ingredients: Potassium Gluconate, Stearic Acid, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

EXP09/14 2KN2158

ACTUAL SIZE

helps support fluid balance, muscle and nerve health**

This product is unconditionally guaranteed for freshness and labeled potency.

RESTORE Potassium is a major mineral needed for well-being. As an essential nutrient, potassium is important for muscle and nerve health and works with sodium to promote fluid balance in the body.**

ID482463

Seals/Symbols

RESTORE

FDA Statement of Identity

DIETARY SUPPLEMENT

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

No artificial colors, artificial flavors, preservatives, lactose or gluten

GLUTEN FREE

General

094 02 1292 : 5T778 UW F1

Brand IP Statement(s)

(C) 2012 Target Brands, Inc.

Suggested/Recommended/Usage/Directions

Suggested Use: Adults, take one caplet daily with a full glass of water or juice.

Precautions

Keep out of reach of children.

Storage

Store in a dry place at room temperature (59(0)-86(0)F).

See for yourself

Potassium Gluconate 595 mg by up&up label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Potassium Gluconate 595 mg by up&up

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Caplet(s) Dosage formOther (e.g. Tea Bag) Amounts shown are per serving.

Potassium

Interacts with
62 drugs
99 mg per serving

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions

Other (inactive) ingredients: Potassium Gluconate, Stearic Acid, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Potassium Gluconate 595 mg by up&up Drug Interactions

Want to check YOUR meds against Potassium Gluconate 595 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
62Drugs
62 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Potassium Gluconate 595 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
The maker

Brand information

Manufacturer and brand details for Potassium Gluconate 595 mg, from the product label.

up&up

See all up&up products
Name
Target Corporation
City
Minneapolis
State
MN
ZipCode
55403
Pharmacist Counseling Corner

Potassium Gluconate 595 mg by up&up: Common Questions

Does Potassium Gluconate 595 mg by up&up interact with any medications?
Yes. Based on its ingredients, Potassium Gluconate 595 mg has a known interaction with 62 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Potassium Gluconate 595 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does potassium do in my body?
Potassium is a mineral your body needs for heart rhythm, muscle function, and nerve signals. Most people get enough from food, but some conditions or medications mean your levels drop and supplementation becomes necessary.
Why is high blood potassium dangerous?
High potassium (hyperkalemia) can cause irregular heartbeats, heart block, low blood pressure, and confusion. It's a serious condition that's why supplements need medical oversight — your doctor checks your level first.
Can I take this if I have kidney disease?
People with kidney disease need to be especially careful because diseased kidneys can't regulate potassium well. Talk with your doctor before considering any potassium supplement — they'll check your levels and advise you personally.
What side effects might I feel from this supplement?
Most common are mild stomach symptoms: abdominal pain, belching, diarrhea, nausea, and vomiting. Serious side effects from dangerously high potassium are rare but can include heart rhythm problems, low blood pressure, and confusion.
Is this safe during pregnancy?
Potassium from your diet is fine and healthy during pregnancy. Supplements, though, should only be used under medical guidance if your doctor thinks you need them — talk with your doctor before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Potassium Gluconate 595 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Potassium Gluconate 595 mg label
Go deeper

The Full Monographs Behind Potassium Gluconate 595 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Potassium Gluconate 595 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Potassium 12 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
  3. Whelton PK, He J, Cutler JA, et al. Effects of oral potassium on blood pressure. Meta-analysis of randomized controlled clinical trials. JAMA 1997;277:1624-32. PubMed
  4. Phillips, C. O., Kashani, A., Ko, D. K., Francis, G., and Krumholz, H. M. Adverse effects of combination angiotensin II receptor blockers plus angiotensin-converting enzyme inhibitors for left ventricular dysfunction: a quantitative review of data from ra DOI
  5. Altieri, P. I., Herrero, C., Suero, R., and Ortiz, A. Bleeding duodenal ulcer in a patient taking slow-releasing potassium tablets. Bol.Asoc.Med P.R. 1977;69(8):276.
  6. Raf, L. E. Enteric-coated potassium chloride tablets and ulcer of the small intestine. Acta Chir Scand Suppl 1967;(374):1-87.
  7. Potassium chloride oral solution [package insert]. Allentown, PA: Lehigh Valley Technologies, Inc.; 2014.
  8. Potassium chloride injection [package insert]. Lake Forest, IL: Hospira Inc.; 2009.
  9. Patel RB, Tannenbaum S, Viana-Tejedor A, et al. Serum potassium levels, cardiac arrhythmias, and mortality following non-ST-elevation myocardial infarction or unstable angina: insights from MERLIN-TIMI 36. Eur Heart J Acute Cardiovasc Care 2017 Feb;6(1):1 PubMed
  10. Malta D, Arcand J, Ravindran A, Floras V, Allard JP, Newton GE. Adequate intake of potassium does not cause hyperkalemia in hypertensive individuals taking medications that antagonize the renin angiotensin aldosterone system. Am J Clin Nutr 2016 Oct;104(4 PubMed
  11. Keskin M, Kaya A, Tatlisu MA, et al. The effect of serum potassium level on in-hospital and long-term mortality in ST elevation myocardial infarction. Int J cardiol. 2016 Oct 15;221:505-10.
  12. Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad

See these in context on the Potassium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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