Premium Probiotic 10 Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Premium Probiotic 10 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Premium Probiotic 10 is a dietary supplement by Puritan's Pride with 11 active ingredients. Its ingredients are commonly taken for constipation and regularity, prebiotic gut health, blood sugar support.Based on those ingredients, 268 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus bulgaricus Lb-87, Lactobacillus acidophilus LA14, Inulin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Premium Probiotic 10 by Puritan's Pride
Ask about any prescription or over-the-counter medication and we check it for interactions with Premium Probiotic 10 by Puritan's Pride — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Premium Probiotic 10 by Puritan's Pride
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Premium Probiotic 10 contains 11 ingredients, most of them live Lactobacillus and Bifidobacterium strains—beneficial bacteria meant to support digestive and gut health. The formula also includes inulin, a prebiotic fiber that feeds the good bacteria in your gut.
The inactive ingredients are common capsule fillers: dicalcium phosphate, vegetable cellulose, silica, and vegetable magnesium stearate.
Does it work?
Moderate evidence
The evidence for this product is mixed because its ingredients have been studied separately, not as a formula. Inulin is possibly effective for obesity, constipation, and diabetes, though the diabetes claim is uncertain.
Two of the Lactobacillus strains show promise: L. acidophilus is possibly effective for irritable bowel syndrome, antibiotic-associated diarrhea, bacterial vaginosis, and Helicobacter pylori infection. The other probiotic strains and most other conditions listed in the data have insufficient evidence or haven't been well studied.
If you're taking this for a specific condition, check with your doctor or pharmacist about whether the evidence supports it for your situation.
How safe is it?
Well-documented data
Inulin is generally well tolerated in food amounts but often causes gas, bloating, flatulence, and gastrointestinal cramps, especially at higher doses over 30 grams—and concentrated supplements aren't well studied for safety. The Lactobacillus strains are generally well tolerated in healthy people but carry a rare theoretical risk: live organisms could cause infection in very ill or severely immunocompromised patients.
Serious infections from these bacteria are uncommon but documented. L. acidophilus in combination with other probiotics may cause gastrointestinal side effects like bloating, diarrhea, flatulence, and abdominal discomfort, though these are uncommon.
For pregnancy, inulin is likely safe, but the Lactobacillus strains haven't been well studied in pregnancy or lactation—discuss with your doctor before using if you're pregnant or nursing.
Meds to double-check
Moderate interaction found
Before taking Premium Probiotic 10, check with your doctor or pharmacist if you take antibiotic drugs—they can reduce how well this probiotic works, so you may need to separate them. If you take antidiabetes medication, watch for signs of low blood sugar (hypoglycemia) like shakiness, sweating, or confusion when you start this product.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
This probiotic blend may help with some digestive issues and conditions like irritable bowel syndrome if you take L. acidophilus-containing products, but evidence for most uses is limited or mixed. The main caution is antibiotics: they'll kill the live bacteria in this supplement, so you'll need to space them apart.
If you take antidiabetes medications, watch your blood sugar, and talk to your doctor or pharmacist before starting if you're very ill, immunocompromised, pregnant, or nursing.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Premium Probiotic 10, straight from the product label.
| Brand | Puritan's Pride |
|---|---|
| Barcode (UPC) | 025077586479 |
| Net contents | 60 Rapid Release Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jan 22, 2021 |
| DSLD ID | 242396 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Premium Probiotic 10 by Puritan's Pride, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Inulin | 200 mg | -- |
| Lactobacillus casei Lc-11 | 0 NP | -- |
| Lactobacillus salivarius Ls-33 | 0 NP | -- |
| Lactobacillus bulgaricus Lb-87 | 0 NP | -- |
| Lactobacillus brevis Lbr-35 | 0 NP | -- |
| Bifidobacterium lactis Bl-04 | 0 NP | -- |
| Lactobacillus paracasei Lpc-37 | 0 NP | -- |
| Lactobacillus acidophilus LA14 | 0 NP | -- |
| Proprietary Probiotic Blend | 0 NP | -- |
| Lactobacillus plantarum 299v | 0 NP | -- |
| Lactobacillus paracasei DSM 13434 | 0 NP | -- |
| Lactobacillus plantarum DSM 15312 | 0 NP | -- |
Other ingredients: Dicalcium Phosphate, Vegetable Cellulose, Silica, Vegetable Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Puritan’s Pride supplements are produced from the finest raw materials under stringent quality control standards. State-of-the-art manufacturing and packaging facilities ensure you the highest quality nutritional supplements money can buy. When it comes to your health...choose the best.
No artificial color, flavor or sweetener, no preservatives, no sugar, no starch, no milk, no lactose, no gluten, no wheat, no fish. Sodium free.
Precautions
Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.
Discontinue use and consult your doctor if any adverse reactions occur.
Keep out of reach of children.
Do not use if seal under cap is broken or missing.
Contains soy ingredients.
Storage
Store unopened container at room temperature.
Brand IP Statement(s)
Lp299v and probi-digestis are registered trademarks of Probi AB.
Copyright 2019 Puritan’s Pride, Inc.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General Statements
To reorder item # 58647 www.puritan.com 1-800-645-1030
20 billion live probiotic cultures per serving guaranteed at time of manufacture -With clinically studied strains for optimum balance -Advanced support for digestive and intestinal health
Seals/Symbols
QA Quality Assured
Formula
Probi-digestis First in probiotics
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: For adults, take two (2) capsules daily, preferably with a meal.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Premium Probiotic 10 by Puritan's Pride label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Premium Probiotic 10 by Puritan's Pride
These are the 11 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Inulin
Interacts with86 drugs
Inulin is a type of plant fiber (a prebiotic) found naturally in foods like chicory root, onions, and garlic, and it is widely added to supplements an...
Inulin monograph & interactionsProprietary Probiotic Blend
- › Lactobacillus casei Lc-11
- › Lactobacillus salivarius Ls-33
- › Lactobacillus bulgaricus Lb-87
- › Lactobacillus brevis Lbr-35
- › Bifidobacterium lactis Bl-04
- › Lactobacillus paracasei Lpc-37
- › Lactobacillus acidophilus LA14
- › Lactobacillus plantarum 299v
- › Lactobacillus paracasei DSM 13434
- › Lactobacillus plantarum DSM 15312
Other (inactive) ingredients: Dicalcium Phosphate, Vegetable Cellulose, Silica, Vegetable Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
Premium Probiotic 10 by Puritan's Pride Drug Interactions
HelloPharmacist Interaction Report
Premium Probiotic 10 by Puritan's Pride has documented interactions through its inulin and two of its Lactobacillus strains (L. bulgaricus and L. acidophilus).
The most serious concern is a Moderate-severity interaction with antibiotic drugs: both Lactobacillus strains contain live organisms that antibiotics may kill, reducing the probiotic's effectiveness. You'll want to separate when you take antibiotics and this product.
Read the full breakdown — every affected drug type, severity by severity
Inulin carries a Minor interaction with antidiabetes drugs—theoretically it might increase the risk of low blood sugar (hypoglycemia), though research on whether inulin actually lowers blood sugar is mixed. If you take diabetes medication, keep an eye on your blood sugar levels when starting this supplement.
Several other ingredients in this blend—Lactobacillus casei, L. salivarius, L. brevis, Bifidobacterium lactis, L. paracasei (two strains), and L. plantarum (two strains)—we could not check because we hold no interaction data for them. Altogether, these interactions span 268 individual medications.
Use the medication search tool on this page to see if any of your drugs are affected.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Premium Probiotic 10?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Premium Probiotic 10 interact with 268 drugs. Click any drug to see the details.
3 of the 11 ingredients in Premium Probiotic 10 interact with drugs. Each result below shows which ingredient is responsible. Lactobacillus bulgaricus Lb-87 Lactobacillus acidophilus LA14 Inulin
AmikacinAmikin, Arikayce
How Amikacin interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Amikacin interactionLactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Amikacin interactionAmoxicillinAmix, Amoram, Amoxident, Amoxil Capsules, Amoxil Injection, Galenamox +3 more
How Amoxicillin interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Amoxicillin interactionLactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Amoxicillin interactionAmoxicillin VeterinaryBiomox
How Amoxicillin Veterinary interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Amoxicillin Veterinary interactionLactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Amoxicillin Veterinary interactionAmoxicillin, Clavulanate PotassiumAugmentin, Augmentin '125/31 SF', Augmentin '250/62 SF', Augmentin XR, Augmentin-Duo 400/57, Clavulin
How Amoxicillin, Clavulanate Potassium interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Amoxicillin, Clavulanate Potassium interactionLactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Amoxicillin, Clavulanate Potassium interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionLactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Amphotericin, Tetracycline interactionLactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Amphotericin, Tetracycline interactionAmpicillinOmnipen, Omnipen-N, Penbritin, Principen, Rimacillin
How Ampicillin interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Ampicillin interactionLactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Ampicillin interactionAmpicillin, SulbactamUnasyn
How Ampicillin, Sulbactam interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Ampicillin, Sulbactam interactionLactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Ampicillin, Sulbactam interactionAvibactam Sodium, CeftazidimeAvycaz
How Avibactam Sodium, Ceftazidime interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Avibactam Sodium, Ceftazidime interactionLactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Avibactam Sodium, Ceftazidime interactionAzithromycinAzasite, Zithromax, Zmax
How Azithromycin interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Azithromycin interactionLactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Azithromycin interactionAztreonamAzactam
How Aztreonam interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Aztreonam interactionLactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Aztreonam interactionBacampicillinPenglobe
How Bacampicillin interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Bacampicillin interactionLactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Bacampicillin interactionBacitracinBaci-IM, Baciguent, Bacitracin Ointment
How Bacitracin interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Bacitracin interactionLactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Bacitracin interactionBenznidazoleBenznidazole
How Benznidazole interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Benznidazole interactionLactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Benznidazole interactionBismuth Subsalicylate, Metronidazole, TetracyclineHelidac
How Bismuth Subsalicylate, Metronidazole, Tetracycline interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionLactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionCapreomycinCapastat
How Capreomycin interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Capreomycin interactionLactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Capreomycin interactionCarbenicillin Indanyl SodiumGeocillin
How Carbenicillin Indanyl Sodium interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Carbenicillin Indanyl Sodium interactionLactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Carbenicillin Indanyl Sodium interactionCefaclorCeclor, Ceclor CD
How Cefaclor interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Cefaclor interactionLactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Cefaclor interactionCefadroxilCef-Tab, Duricef, Ultracef
How Cefadroxil interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Cefadroxil interactionLactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Cefadroxil interactionCefamandoleMandol
How Cefamandole interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Cefamandole interactionLactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Cefamandole interactionCefazolinAncef
How Cefazolin interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Cefazolin interactionLactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Cefazolin interactionCefdinirOmnicef
How Cefdinir interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Cefdinir interactionLactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Cefdinir interactionCefditoren PivoxilSpectracef
How Cefditoren Pivoxil interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Cefditoren Pivoxil interactionLactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Cefditoren Pivoxil interactionCefepimeMaxipime
How Cefepime interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Cefepime interactionLactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Cefepime interactionCefiderocol Sulfate TosylateFetroja
How Cefiderocol Sulfate Tosylate interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Cefiderocol Sulfate Tosylate interactionLactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Cefiderocol Sulfate Tosylate interactionCefiximeSuprax
How Cefixime interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Cefixime interactionLactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Cefixime interactionCefmetazoleZefazone
How Cefmetazole interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Cefmetazole interactionLactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Cefmetazole interactionCefonicidMonocid
How Cefonicid interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Cefonicid interactionLactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Cefonicid interactionCefoperazoneCefobid
How Cefoperazone interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Cefoperazone interactionLactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Cefoperazone interactionCefotaximeClaforan
How Cefotaxime interacts with Premium Probiotic 10 — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Bulgaricus Lb-87Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus Lb-87 + Cefotaxime interactionLactobacillus Acidophilus La14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La14 + Cefotaxime interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Premium Probiotic 10 with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Lactobacillus bulgaricus Lb-87
Antibiotic Drugs
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L. delbrueckii.
Lactobacillus delbrueckii preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. delbrueckii preparations by at least two hours.
Lactobacillus acidophilus LA14
Antibiotic Drugs
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.
Inulin
Antidiabetes Drugs
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Some clinical research shows that inulin improves glycemic control in patients with diabetes; however, it is unclear if it has hypoglycemic effects.
Brand information
Manufacturer and brand details for Premium Probiotic 10, from the product label.
Puritan's Pride
See all Puritan's Pride products- Name
- Puritan's Pride, Inc.
- City
- Ronkonkoma
- State
- NY
- ZipCode
- 11779
- Phone Number
- 1-800-645-1030
- Web Address
- www.puritan.com
Premium Probiotic 10 by Puritan's Pride: Common Questions
Does Premium Probiotic 10 by Puritan's Pride interact with any medications?
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Premium Probiotic 10’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Inulin
Interacts with 86 drugsInulin is a type of plant fiber (a prebiotic) found naturally in foods like chicory root, onions, and garlic, and it is widely added to supplements and processed foods. It may help with regu...
Read the full Inulin monograph → Herb & supplement monographLactobacillus Delbrueckii
Interacts with 182 drugsLactobacillus delbrueckii is a 'friendly' bacterium used in food fermentation and sold as a probiotic, often as part of multi-strain products. It is generally considered safe for healthy peo...
Read the full Lactobacillus Delbrueckii monograph → Herb & supplement monographLactobacillus Acidophilus
Interacts with 182 drugsLactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...
Read the full Lactobacillus Acidophilus monograph →Sources & How We Checked
Premium Probiotic 10's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 41 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Inulin 17 references
- Williams CM. Effects of inulin on lipid parameters in humans. J Nutr 1999 Jul;129(7 Suppl):1471S-3S. PubMed
- Pedersen A, Sandstrom B, Van Amelsvoort JM. The effect of ingestion of inulin on blood lipids and gastrointestinal symptoms in healthy females. Br J Nutr 1997;78:215-22. PubMed
- Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001;73:415S-420S. PubMed
- Bonnema AL, Kolberg LW, Thomas W, Slavin JL. Gastrointestinal tolerance of chicory inulin products. J Am Diet Assoc 2010;110(6):865-8. PubMed
- Dehghan P, Gargari BP, Jafar-Abadi MA, Aliasgharzadeh A. Inulin controls inflammation and metabolic endotoxemia in women with type 2 diabetes mellitus: a randomized-controlled clinical trial. Int J Food Sci Nutr 2014;65(1):117-23. PubMed
- Guess ND, Dornhorst A, Oliver N, Frost GS. A randomised crossover trial: the effect of inulin on glucose homeostasis in subtypes of prediabetes. Ann Nutr Metab 2016;68(1):26-34. PubMed
- Marteau P, Jacobs H, Cazaubiel M, Signoret C, Prevel JM, Housez B. Effects of chicory inulin in constipated elderly people: a double-blind controlled trial. Int J Food Sci Nutr 2011;62(2):164-70. PubMed
- Mensink MA, Frijlink HW, van der Voort Maarschalk K, Hinrichs WL. Inulin, a flexible oligosaccharide I: review of its physicochemical characteristics. Carbohydr Polym 2015;130:405-19. PubMed
- Slavin J, Feirtag J. Chicory inulin does not increase stool weight or speed up intestinal transit time in healthy male subjects. Food Funct. 2011;2(1):72-7. PubMed
- Micka A, Siepelmeyer A, Holz A, Theis S, Schön C. Effect of consumption of chicory inulin on bowel function in healthy subjects with constipation: a randomized, double-blind, placebo-controlled trial. Int J Food Sci Nutr. 2017;68(1):82-89. PubMed
- Smiljanec K, Mitchell CM, Privitera OF, Neilson AP, Davy KP, Davy BM. Pre-meal inulin consumption does not affect acute energy intake in overweight and obese middle-aged and older adults: A randomized controlled crossover pilot trial. Nutr Health. 2017;23 PubMed
- Cai X, Yu H, Liu L, et al. Milk powder co-supplemented with inulin and resistant dextrin improves glycemic control and insulin resistance in elderly type 2 diabetes mellitus: a 12-week randomized, double-blind, placebo-controlled trial. Mol Nutr Food Res PubMed
- Rao M, Gao C, Xu L, et al. Effect of inulin-type carbohydrates on insulin resistance in patients with type 2 diabetes and obesity: a systematic review and meta-analysis. J Diabetes Res. 2019;2019:5101423. PubMed
- Mitchell CM, Davy BM, Ponder MA, et al. Prebiotic Inulin Supplementation and Peripheral Insulin Sensitivity in adults at Elevated Risk for Type 2 Diabetes: A Pilot Randomized Controlled Trial. Nutrients 2021;13(9):3235. PubMed
- Li L, Li P, Xu L. Assessing the effects of inulin-type fructan intake on body weight, blood glucose, and lipid profile: A systematic review and meta-analysis of randomized controlled trials. Food Sci Nutr 2021;9(8):4598-4616. PubMed
- Ziaei R, Shahshahan Z, Ghasemi-Tehrani H, Heidari Z, Ghiasvand R. Effects of inulin-type fructans with different degrees of polymerization on inflammation, oxidative stress and endothelial dysfunction in women with polycystic ovary syndrome: A randomized,
- Risso D, Kaczmarczyk M, Laurie I, et al. Moderate intakes of soluble corn fibre or inulin do not cause gastrointestinal discomfort and are well tolerated in healthy children. Int J Food Sci Nutr 2022;73(8):1104-1115. PubMed
Lactobacillus Delbrueckii 9 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
- Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
- Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
- Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.
- Neonakis IK, Skamagkas I, Stafylaki D, Maraki S. Lactobacillus delbrueckii urinary tract infection in a male patient: a case report. Germs 2022;12(2):304-307. PubMed
- Maillet F, Passeron A, Podglajen I, Ranque B, Pouchot J. Lactobacillus delbrueckii urinary tract infection in a male patient. Med Mal Infect 2019;49(3):226-228. PubMed
- Darbro BW, Petroelje BK, Doern GV. Lactobacillus delbrueckii as the cause of urinary tract infection. J Clin Microbiol 2009;47(1):275-7.
See these in context on the Lactobacillus Delbrueckii monograph →
Lactobacillus Acidophilus 15 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
- Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
- Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
- Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
- Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
- Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
- Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
- Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.
See these in context on the Lactobacillus Acidophilus monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC