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Dietary supplement

Freeze Dried Rich Pericarp Mangosteen 515 mg Ingredients & Drug Interactions

by Natural Home Cures

Freeze Dried Rich Pericarp Mangosteen 515 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Freeze Dried Rich Pericarp Mangosteen 515 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Freeze Dried Rich Pericarp Mangosteen 515 mg is a dietary supplement by Natural Home Cures with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, anti-inflammatory support, immune support.Based on those ingredients, 125 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic freeze dried Mangosteen. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Freeze Dried Rich Pericarp Mangosteen 515 mg by Natural Home Cures

Ask about any prescription or over-the-counter medication and we check it for interactions with Freeze Dried Rich Pericarp Mangosteen 515 mg by Natural Home Cures — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Freeze Dried Rich Pericarp Mangosteen 515 mg by Natural Home Cures

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: 515 mg of organic freeze-dried mangosteen pericarp (the rind of the mangosteen fruit). The capsule itself is made from a veggie-based material.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Mangosteen's overall clinical evidence instead.

Moderate

Some clinical evidence supports Mangosteen for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Periodontitis — rated "Possibly Effective" (Natural Medicines).

Mangosteen has possibly effective evidence for periodontitis (gum disease). For male-pattern hair loss (androgenic alopecia) and Alzheimer's disease, there isn't enough reliable evidence yet to say whether it works.

The same goes for atopic dermatitis (eczema) — the data we hold doesn't establish effectiveness.

The evidence, ingredient by ingredient Mangosteen

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Mangosteen is generally well tolerated when used as a food, but how safe concentrated supplements are over the long term hasn't been thoroughly studied. A small number of trial participants taking mangosteen extract reported mild tiredness, headache, dizziness, malaise, constipation, nausea, vomiting, diarrhea, dry throat, and cough — though it's unclear whether mangosteen was actually responsible.

The safety data advises against use of supplement amounts during pregnancy and breastfeeding because there isn't enough information to know either way.

Side effects, ingredient by ingredient Mangosteen

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Mangosteen.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 125 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Blood thinners and antiplatelet drugs (a moderate-severity interaction that may increase bleeding risk) should be double-checked before you start this product. Also flag donepezil (Aricept) if you take it, since mangosteen may increase its effects in your brain.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

If you have gum disease and no bleeding disorders or medications that thin your blood, this might be worth a conversation with your doctor or pharmacist. If you take blood thinners or donepezil, check with your own healthcare provider before adding this supplement — the interaction risk needs a personal look at your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 18, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Freeze Dried Rich Pericarp Mangosteen 515 mg, straight from the product label.

Brand Natural Home Cures
Barcode (UPC) 000309510910
Net contents 120 Vegetable Capsule(s)
Market status On market
Date entered into DSLD Dec 18, 2021
DSLD ID 258069
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Freeze Dried Rich Pericarp Mangosteen 515 mg by Natural Home Cures, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
60
UPC/BARCODE
000309510910
IngredientAmount% DV
organic freeze dried Mangosteen1030 mg--

Other ingredients: Veggie Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children 18, and individuals with known medical conditions should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children 18, and individuals with known medical conditions should consult a physician before using this or any dietary supplement.

This product is manufactured and package in a facility which may also process milk, soy, wheat, egg, peanuts, tree nuts, fish and crustacean shellfish.

Storage

Store in a cool dry place.

FDA Statement of Identity

Dietary Supplement

Formulation

Our Mangosteen is grown without the use of chemicals, pesticides, herbicides, or synthetic fertilizers.

To ensure the maximum health benefits; We immediately freeze dry our rich pericap Mangosteen after harvesting turning it into a pure rich Mangosteen powder.

General Statements

High antioxidants Supports a healthy immune system Promotes a healthy overall well being

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take two (2) capsules, 3 times a day.

FDA Disclaimer Statement

The FDA & Health Canada have not evaluated this product. This product is not intended to diagnose, treat, cure, mitigate or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Freeze Dried Rich Pericarp Mangosteen 515 mg by Natural Home Cures label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Freeze Dried Rich Pericarp Mangosteen 515 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Freeze Dried Rich Pericarp Mangosteen 515 mg by Natural Home Cures

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Organic freeze dried Mangosteen

Interacts with
125 drugs
1030 mg per serving

Mangosteen is a tropical fruit whose rind is rich in plant compounds called xanthones that act as antioxidants. While it is popular in juices and supp...

Organic freeze dried Mangosteen monograph & interactions

Other (inactive) ingredients: Veggie Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Freeze Dried Rich Pericarp Mangosteen 515 mg by Natural Home Cures Drug Interactions

Want to check YOUR meds against Freeze Dried Rich Pericarp Mangosteen 515 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
125Drugs
122 Moderate 3 Minor

Ingredients driving the most interactions

organic freeze dried Mangosteen 125

Individual Drug Interactions

The ingredients in Freeze Dried Rich Pericarp Mangosteen 515 mg interact with 125 drugs. Click any drug to see the details.

1 of the 1 ingredient in Freeze Dried Rich Pericarp Mangosteen 515 mg interact with drugs. Each result below shows which ingredient is responsible. organic freeze dried Mangosteen

Each ingredient & the kinds of drugs it affects

For each ingredient in Freeze Dried Rich Pericarp Mangosteen 515 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

organic freeze dried Mangosteen2 drug types · 125 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
In vitro and animal research shows that gamma-mangostin, a constituent of mangosteen, is a potent and competitive antagonist of the serotonin 2A (5-HT2A) receptor. Antagonism of the 5-HT2A receptor is believed to reduce platelet aggregation.

Likelihood Possible Evidence D
Donepezil (Aricept)

Theoretically, concomitant use of mangosteen with donepezil might increase the effects of donepezil.
Animal research shows that concomitant use of an aqueous extract of mangosteen pericarp with donepezil increases brain concentrations of donepezil at 4 hours by 64% without associated effects on systemic exposure.

Likelihood Possible Evidence D
organic freeze dried Mangosteen full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Freeze Dried Rich Pericarp Mangosteen 515 mg, from the product label.

Natural Home Cures

See all Natural Home Cures products
Name
Natural Home Cures
Street Address
#65 - 55 Manison Street
City
Poughkeepsie
State
NY
ZipCode
12601
Phone Number
(845) 875-6155
Web Address
www.mymangosteencures.net
Pharmacist Counseling Corner

Freeze Dried Rich Pericarp Mangosteen 515 mg by Natural Home Cures: Common Questions

Does Freeze Dried Rich Pericarp Mangosteen 515 mg by Natural Home Cures interact with any medications?
Yes. Based on its ingredients, Freeze Dried Rich Pericarp Mangosteen 515 mg has a known interaction with 125 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Freeze Dried Rich Pericarp Mangosteen 515 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The safety data we have advises against supplement amounts during pregnancy and while breastfeeding because there isn't enough information either way. Talk it over with your doctor or pharmacist — they can give you personalized guidance based on your situation.
What are the side effects?
Some people in trials reported mild tiredness, headache, dizziness, digestive symptoms like nausea or diarrhea, and symptoms like a dry throat or cough. It's not clear whether mangosteen caused them. Most people tolerate it without trouble.
Does this really help with gum disease?
Mangosteen has possibly effective evidence for periodontitis (gum disease), which means there's some promising research but it's not rock-solid yet. If you're considering it for that reason, mention it to your dentist or doctor.
Will it help my hair loss?
The evidence we hold doesn't establish whether mangosteen works for male-pattern hair loss. You'd want to discuss other proven options with your doctor.
Is there anything else in this capsule besides mangosteen?
The active ingredient is the mangosteen pericarp. The capsule itself is made from a plant-based material. There are no added fillers or binders.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Freeze Dried Rich Pericarp Mangosteen 515 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Freeze Dried Rich Pericarp Mangosteen 515 mg label
Go deeper

The Full Monographs Behind Freeze Dried Rich Pericarp Mangosteen 515 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Mangosteen

Interacts with 125 drugs

Mangosteen is a tropical fruit whose rind is rich in plant compounds called xanthones that act as antioxidants. While it is popular in juices and supplements for inflammation, immune support...

Read the full Mangosteen monograph →
Sources

Sources & How We Checked

Freeze Dried Rich Pericarp Mangosteen 515 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Mangosteen 6 references
  1. Chairungsrilerd N, Furukawa K, Ohta T, et al. Histaminergic and serotonergic receptor blocking substances from the medicinal plant Garcinia mangostana. Planta Med 1996;62:471-2.
  2. Wong LP, Klemmer PJ. Severe lactic acidosis associated with juice of the mangosteen fruit Garcinia mangostana. Am J Kidney Dis 2008;51:829-33. PubMed
  3. Furukawa, K., Chairungsrilerd, N., Ohta, T., Nozoe, S., and Ohizumi, Y. [Novel types of receptor antagonists from the medicinal plant Garcinia mangostana]. Nippon Yakurigaku Zasshi 1997;110 Suppl 1:153P-158P. PubMed
  4. Chairungsrilerd, N., Furukawa, K., Tadano, T., Kisara, K., and Ohizumi, Y. Effect of gamma-mangostin through the inhibition of 5-hydroxy-tryptamine2A receptors in 5-fluoro-alpha-methyltryptamine-induced head-twitch responses of mice. Br J Pharmacol. 1998
  5. Suthammarak W, Numpraphrut P, Charoensakdi R, et al. Antioxidant-enhancing property of the polar fraction of mangosteen pericarp extract and evaluation of its safety in humans. Oxid Med Cell Longev 2016;2016:1293036. PubMed
  6. Bae M, Han SY, Kim ES, et al. Effect of Water Extract of Mangosteen Pericarp on Donepezil Pharmacokinetics in Mice. Molecules 2021;26(17):5246. PubMed

See these in context on the Mangosteen monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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