Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Pro-GH Fruit Punch Flavor Ingredients & Drug Interactions

by NOW Sports

Pro-GH Fruit Punch Flavor label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pro-GH Fruit Punch Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Pro-GH Fruit Punch Flavor is a dietary supplement by NOW Sports with 6 active ingredients. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 633 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are GABA, L-Arginine, L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Pro-GH Fruit Punch Flavor by NOW Sports

Ask about any prescription or over-the-counter medication and we check it for interactions with Pro-GH Fruit Punch Flavor by NOW Sports — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Pro-GH Fruit Punch Flavor by NOW Sports

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 6 of its 6 active ingredients.
  • “L-Ornithine” is listed as a grouped ingredient — the label gives one combined amount (1.50 Gram(s)) without saying how much of each component you get.
  • “L-Lysine” is listed as a grouped ingredient — the label gives one combined amount (500 mg) without saying how much of each component you get.

Pro-GH Fruit Punch Flavor contains six active amino acids: L-glutamine, glycine, L-arginine, L-lysine hydrochloride, L-ornithine hydrochloride, and GABA. These are amino acids and neurotransmitter precursors often used in sports nutrition to support muscle recovery and athletic performance.

The powder also contains inactive ingredients—fructose, citric acid, silicon dioxide, malic acid, natural flavors, beet powder, and organic stevia leaf extract—which serve as sweeteners, thickeners, and flavoring.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support optimal sports performance and muscle growth.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Muscle strength, Physical performance, Postoperative recovery, Wound healing — and 4 related terms.
  • The strongest evidence on file: Ornithine is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Effective" for Postoperative recovery.
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance.

The evidence for these ingredients is mixed and limited. L-glutamine is rated Effective for sickle cell disease, and Possibly Effective for HIV/AIDS-related wasting, postoperative recovery, and critical illness.

L-arginine has no effectiveness ratings in our data. Glycine is Possibly Effective for schizophrenia; L-lysine is Possibly Effective for cold sores (herpes labialis).

L-ornithine and GABA both have ratings of Insufficient Reliable Evidence for their proposed uses—meaning the data we hold doesn't establish whether they work. For general athletic recovery or performance, the evidence supporting these amino acids remains limited.

The evidence, ingredient by ingredient Glutamine Glycine L-arginine Ornithine Gamma-aminobutyric Acid (gaba) Lysine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

These ingredients are generally well tolerated at typical doses, though each carries caveats. L-glutamine may cause belching, bloating, constipation, diarrhea, flatulence, nausea, vomiting, headache, or muscle pain; high doses (10–30 grams daily) increase GI upset.

Glycine can rarely cause mild sedation, insomnia, fatigue, memory problems, or nausea; soft stools and dry mouth have also been reported. L-arginine often causes abdominal pain, bloating, nausea, diarrhea, headache, insomnia, or flushing.

L-lysine may trigger abdominal pain, diarrhea, or indigestion. GABA can cause drowsiness, nausea, muscle weakness, or gastric upset.

L-ornithine hydrochloride has no adverse effects listed in our data. People with kidney or liver disease should use L-glutamine only under medical supervision.

There is not enough reliable safety data for L-arginine, glycine, L-lysine, L-ornithine, or GABA in pregnancy or while breastfeeding—talk with your doctor or pharmacist before use if you're pregnant or nursing.

Side effects, ingredient by ingredient Glutamine Glycine L-arginine Ornithine Gamma-aminobutyric Acid (gaba) Lysine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 6 matched ingredients can interact with medications — Lysine, Gamma-aminobutyric Acid (gaba), L-arginine, Glutamine, Glycine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; seizure medications; diabetes medications.
  • For scale: 633 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Pro-GH, check with your doctor or pharmacist if you take blood pressure medications (ACE inhibitors, ARBs, or other antihypertensives), potassium-sparing diuretics, blood thinners or antiplatelet drugs, diabetes medications, anticonvulsants, clozapine (Clozaril), sildenafil (Viagra), isoproterenol (Isuprel), or CNS depressants like sleep aids or strong pain relievers. L-arginine and GABA can lower blood pressure; L-arginine may also raise potassium and increase bleeding risk.

Severity ranges from Moderate (most concerning) to Minor.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Pro-GH is a multi-amino acid supplement aimed at muscle recovery and sports performance. If you take blood pressure medications (especially ACE inhibitors or ARBs), blood thinners, diabetes drugs, anticonvulsants, or psychiatric medications like clozapine, you'll need to check this product against your specific medications before starting.

Talk with your doctor or pharmacist to confirm it's right for you and your health situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pro-GH Fruit Punch Flavor, straight from the product label.

Brand NOW Sports
Barcode (UPC) 733739002075
Net contents 612 Gram(s); 21.6 oz.
Market status On market
Date entered into DSLD Dec 22, 2019
DSLD ID 210369
Product type Other Combinations
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Women (not pregnant or lactating), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pro-GH Fruit Punch Flavor by NOW Sports, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
18 Gram(s)
Maximum serving Sizes:
18 Gram(s)
Servings per container
34
UPC/BARCODE
733739002075
IngredientAmount% DV
Calories35 Calorie(s)--
Total Carbohydrates9 Gram(s)3%
L-Glutamine2 Gram(s)--
Glycine2 Gram(s)--
L-Arginine1.5 Gram(s)--
L-Lysine Hydrochloride669 mg--
L-Ornithine Hydrochloride2 Gram(s)--
L-Ornithine1.5 Gram(s)--
Added Sugars8 Gram(s)16%
GABA500 mg--
Total Sugars8 Gram(s)--
L-Lysine500 mg--

Other ingredients: Fructose, Citric Acid, Silicon Dioxide, Malic Acid, Natural flavors, Beet powder, organic Stevia leaf extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Usage: Mix 1 level scoop with 4-6 oz. of water or juice. For best results take on an empty stomach 20 minutes before bed or exercise - 5 days on/2 days off.

Formula

NOW Sports Pro-GH is an amino acid supplement formulated to support optimal sports performance. Pro-GH has arginine, ornithine, lysine, and glutamine, which are critical for normal endocrine function and help to promote muscle tissue growth and recovery. These same amino acids are essential for the production and maintenance of nitric oxide (NO) within blood vessels, further supporting the body's optimal response to intense physical training. Glycine, known for its role in glycogen synthesis, has been included to support muscular energy output. Finally, glutamine and glycine help to support healthy immune system responses, especially during times of physical stress and intense exercise. NOW Sports Pro-GH thus combines the amino acids needed to help attain your training goals into one convenient product.

Amino acids

6 power aminos

Triangle K

FDA Disclaimer Statement

These statements have no been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Caution: For adults only. This product may cause temporary, but transient GI discomfort.

Do not use if pregnant or nursing. Consult physician if taking medication (including those that affect kidney function or blood pressure) or have a medical condition (including glaucoma, herpes simplex, impaired kidney function, coronary artery disease, or if you have had a myocardial infarction).

Keep out of reach of children.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Seals/Symbols

GMP Quality Assured

Informed-sport.com Trusted by sport Informed-choice.org Trusted by sport

Steroid free Triangle K

Formulation

Muscle recovery Nitric oxide promoter

Steroid free No aspartame No sucralose No artificial sweeteners No acesulfame-k

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients.

Natural color variation may occur in this product.

FDA Statement of Identity

A Dietary Supplement

General Statements

This product is sold by weight not volume.

Storage

Store in a cool, dry, dark place after opening.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pro-GH Fruit Punch Flavor by NOW Sports label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pro-GH Fruit Punch Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pro-GH Fruit Punch Flavor by NOW Sports

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size18 Gram(s) Dosage formPowder Servings per container34 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Glutamine

Interacts with
50 drugs
2 Gram(s) per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions

Glycine

Interacts with
1 drug
2 Gram(s) per serving

Glycine is a non-essential amino acid your body makes on its own and that also appears in protein-rich foods. It is most studied for improving sleep q...

Glycine monograph & interactions

L-Arginine

Interacts with
403 drugs
1.5 Gram(s) per serving

L-arginine is an amino acid that the body uses to make nitric oxide, a substance that helps blood vessels relax and widen. It is popularly used for bl...

L-Arginine monograph & interactions

L-Ornithine

No known
interactions
1.5 Gram(s) per serving

Ornithine is a non-essential amino acid your body makes naturally as part of the urea cycle, which helps remove ammonia. It is sold as a supplement fo...

L-Ornithine monograph & interactions

GABA

Interacts with
419 drugs
500 mg per serving

GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep...

GABA monograph & interactions

L-Lysine

Interacts with
1 drug
500 mg per serving

Lysine is an essential amino acid your body cannot make on its own, so it must come from food or supplements. People most often take extra lysine to t...

L-Lysine monograph & interactions

Other (inactive) ingredients: Fructose, Citric Acid, Silicon Dioxide, Malic Acid, Natural flavors, Beet powder, Organic Stevia leaf extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pro-GH Fruit Punch Flavor by NOW Sports Drug Interactions

Want to check YOUR meds against Pro-GH Fruit Punch Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
633Drugs
445 Moderate 188 Minor

Ingredients driving the most interactions

GABA 419
L-Arginine 403
L-Glutamine 50
Glycine 1
L-Lysine 1

Individual Drug Interactions

The ingredients in Pro-GH Fruit Punch Flavor interact with 633 drugs. Click any drug to see the details.

5 of the 6 ingredients in Pro-GH Fruit Punch Flavor interact with drugs. Each result below shows which ingredient is responsible. GABA L-Arginine L-Glutamine Glycine L-Lysine

Each ingredient & the kinds of drugs it affects

For each ingredient in Pro-GH Fruit Punch Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

GABA2 drug types · 419 drugs

Antihypertensive Drugs

Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Some clinical research shows that GABA can decrease blood pressure in patients with hypertension.

Likelihood Possible Evidence B
Cns Depressants

Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants. However, it is unclear if this concern is clinically relevant.
Endogenous GABA has well-established relaxant effects and GABA(A) receptors have an established physiological role in sleep. However, the effects of GABA supplements are unclear, as it is unknown whether exogenous GABA crosses the blood-brain barrier. Although there have been limited reports of drowsiness or tiredness with GABA supplements, these effects have not been widely reported in clinical studies. Additionally, intravenous GABA 0.1-1 mg/kg has been shown to induce anxiety in a dose-dependent manner.

Likelihood Unlikely Evidence D
GABA full monograph & interactions

L-Arginine9 drug types · 403 drugs

Ace Inhibitors (Aceis)

Theoretically, concomitant use of L-arginine and ACE inhibitors may increase the risk for hypotension and hyperkalemia.
Combining L-arginine with some antihypertensive drugs, especially ACE inhibitors, seems to have additive vasodilating and blood pressure-lowering effects. Furthermore, ACE inhibitors can increase potassium levels. Use of L-arginine has been associated with hyperkalemia in some patients. Theoretically, concomitant use of ACE inhibitors with L-arginine may increases the risk of hyperkalemia.

Likelihood Probable Evidence D
Angiotensin Receptor Blockers (Arbs)

Theoretically, concomitant use of L-arginine and ARBs may increase the risk of hypotension and hyperkalemia.
L-arginine increases nitric oxide, which causes vasodilation. Combining L-arginine with ARBs seems to increase L-arginine-induced vasodilation. Furthermore, ARBs can increase potassium levels. Use of L-arginine has been associated with hyperkalemia in some patients. Theoretically, concomitant use of ARBs with L-arginine may increases the risk of hyperkalemia.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, concomitant use of L-arginine with anticoagulant and antiplatelet drugs might have additive effects and increase the risk of bleeding.
Preliminary research suggests that L-arginine infusions reduce platelet aggregation in humans. The clinical significance of this effect is unclear.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, concomitant use of L-arginine might have additive effects with antidiabetes drugs.
Preliminary clinical research shows that L-arginine decreases blood glucose levels in patients with type 2 diabetes.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, concomitant use of L-arginine and antihypertensive drugs may increase the risk of hypotension.
L-arginine increases nitric oxide, which causes vasodilation. Clinical evidence shows that L-arginine can reduce blood pressure in some individuals with hypertension. Furthermore, combining L-arginine with some antihypertensive drugs seems to have additive vasodilating and blood pressure-lowering effects.

Likelihood Probable Evidence D
Isoproterenol (Isuprel)

Theoretically, concurrent use of isoproterenol and L-arginine might result in additive effects and hypotension.
Preliminary clinical evidence suggests that L-arginine enhances isoproterenol-induced vasodilation in patients with essential hypertension or a family history of essential hypertension.

Likelihood Probable Evidence D
Potassium-Sparing Diuretics

Theoretically concomitant use of potassium-sparing diuretics with L-arginine may increases the risk of hyperkalemia.
Potassium-sparing diuretics can increase potassium levels. Use of L-arginine has been associated with hyperkalemia in some patients.

Likelihood Possible Evidence D
Sildenafil (Viagra)

Theoretically, concurrent use of sildenafil and L-arginine might increase the risk for hypotension.
In vivo, concurrent use of L-arginine and sildenafil has resulted in increased vasodilation. Theoretically, concurrent use might have additive vasodilatory and hypotensive effects. However, in studies evaluating the combined use of L-arginine and sildenafil for erectile dysfunction, hypotension was not reported.

Likelihood Possible Evidence D
Testosterone

Theoretically, concomitant use of L-arginine and testosterone might have additive effects.
In clinical research, L-arginine increases the level of testosterone in male patients with erectile dysfunction. The clinical significance of this finding is unclear.

Likelihood Possible Evidence D
L-Arginine full monograph & interactions

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions

Glycine1 drug type · 1 drug

Clozapine (Clozaril)

Theoretically, glycine might decrease the effectiveness of clozapine.
One small clinical study in patients with schizophrenia shows that adding glycine to clozapine therapy worsens symptoms of schizophrenia when compared with clozapine alone. The mechanism of this interaction is unclear.

Likelihood Probable Evidence B
Glycine full monograph & interactions

L-Lysine1 drug type · 1 drug

5-Ht4 Agonists

Theoretically, lysine may reduce the effects of 5-HT4 agonists.
Animal research suggests that L-lysine is a partial serotonin receptor 4 (5-HT4) antagonist and inhibits diarrhea induced by the 5-HT4 agonist, 5-hydroxytryptophane.

Likelihood Unlikely Evidence D
L-Lysine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pro-GH Fruit Punch Flavor, from the product label.

NOW Sports

See all NOW Sports products
Name
NOW Foods
Street Address
395 S. Glen Ellyn Rd.
City
Bloomingdale
State
IL
ZipCode
60108
Web Address
nowsportsproducts.com
Pharmacist Counseling Corner

Pro-GH Fruit Punch Flavor by NOW Sports: Common Questions

Does Pro-GH Fruit Punch Flavor by NOW Sports interact with any medications?
Yes. Based on its ingredients, Pro-GH Fruit Punch Flavor has a known interaction with 633 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pro-GH Fruit Punch Flavor contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe if I'm pregnant or breastfeeding?
L-glutamine is rated Likely Safe in pregnancy and lactation. For L-arginine, the data shows Possibly Safe in pregnancy but no rating for breastfeeding. For L-lysine, L-ornithine, GABA, and glycine, there isn't enough reliable information—the data advises against supplement doses unless your doctor recommends them. Talk with your doctor or pharmacist before using this product during pregnancy or while nursing.
What are the most common side effects?
GI upset is most common: belching, bloating, constipation, diarrhea, nausea, vomiting, and abdominal pain can occur with L-glutamine, L-arginine, and L-lysine. L-arginine may also cause headache, insomnia, or flushing. GABA can cause drowsiness and muscle weakness. Most adverse effects are mild and dose-related; they typically resolve if you stop taking the supplement.
Will this help me build muscle or improve athletic performance?
L-ornithine is rated Possibly Effective for athletic performance. L-glutamine and the other amino acids are commonly used in sports supplements, but the evidence in our data doesn't firmly establish that they improve strength or muscle gain for most people. Individual results vary, and you may want to discuss realistic expectations with your doctor or a sports nutritionist.
Can I take this with blood pressure medication?
L-arginine and GABA in this product may lower blood pressure, and L-arginine may also raise potassium levels. If you take blood pressure drugs—especially ACE inhibitors (like lisinopril) or ARBs (like losartan)—check with your doctor or pharmacist first. Combining them without supervision could cause dangerously low blood pressure or other complications.
What's GABA, and will it make me drowsy?
GABA is gamma-aminobutyric acid, a natural brain chemical that promotes relaxation. Drowsiness is a reported side effect, though it's mild and not common. If you take sedatives or sleep aids, GABA may add to that drowsy effect—check with your pharmacist before combining them.
Does this product have any fillers or additives?
Yes. Besides the six active amino acids, it contains fructose, citric acid, silicon dioxide, malic acid, natural flavors, beet powder, and organic stevia leaf extract as inactive ingredients for sweetness, texture, and flavor.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pro-GH Fruit Punch Flavor is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pro-GH Fruit Punch Flavor label
Go deeper

The Full Monographs Behind Pro-GH Fruit Punch Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph → Herb & supplement monograph

Glycine

Interacts with 1 drug

Glycine is a non-essential amino acid your body makes on its own and that also appears in protein-rich foods. It is most studied for improving sleep quality, where early research is promisin...

Read the full Glycine monograph → Herb & supplement monograph

L-arginine

Interacts with 403 drugs

L-arginine is an amino acid that the body uses to make nitric oxide, a substance that helps blood vessels relax and widen. It is popularly used for blood pressure, erectile dysfunction, and...

Read the full L-arginine monograph → Herb & supplement monograph

Ornithine

Ornithine is a non-essential amino acid your body makes naturally as part of the urea cycle, which helps remove ammonia. It is sold as a supplement for fatigue, exercise recovery, and sleep,...

Read the full Ornithine monograph → Herb & supplement monograph

Gamma-aminobutyric Acid (gaba)

Interacts with 419 drugs

GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep. The science behind oral GABA supplemen...

Read the full Gamma-aminobutyric Acid (gaba) monograph → Herb & supplement monograph

Lysine

Interacts with 1 drug

Lysine is an essential amino acid your body cannot make on its own, so it must come from food or supplements. People most often take extra lysine to try to prevent or shorten cold sores, but...

Read the full Lysine monograph →
Sources

Sources & How We Checked

Pro-GH Fruit Punch Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 102 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Glycine 5 references
  1. Heresco-Levy U, Javitt DC, Ermilov M, et al. Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia. Arch Gen Psychiatry 1999;56:29-36.. PubMed
  2. Potkin SG, Jin Y, Bunney BG, Costa J, Gulasekaram B. Effect of clozapine and adjunctive high-dose glycine in treatment-resistant schizophrenia. Am J Psychiatry 1999;156:145-7.. PubMed
  3. Gusev EI, Skvortsova VI, Dambinova SA, et al. Neuroprotective effects of glycine for therapy of acute ischaemic stroke. Cerebrovasc Dis 2000;10:49-60. PubMed
  4. Inagawa K, Kawai N, Ono K, Sukegawa E, Tsubuku S, Takahashi M. Assessment of acute adverse effects of glycine ingestion at a high dose in human volunteers. Seikatsu Eisei. 2006; 50:27-32.
  5. Woods SW, Walsh BC, Hawkins KA, Miller TJ, Saksa JR, D'Souza DC, Pearlson GD, Javitt DC, McGlashan TH, Krystal JH. Glycine treatment of the risk syndrome for psychosis: report of two pilot studies. Eur Neuropsychopharmacol. 2013 Aug;23(8):931-40. PubMed

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L-arginine 66 references
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Lysine 7 references
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Ornithine 1 reference
  1. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source

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Gamma-aminobutyric Acid (gaba) 12 references
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