Interactions on record — worth a quick check against your medications. Based on 2 of 10 ingredients. Check your meds →
Dietary supplement

Probiotic 10 Premium Ingredients & Drug Interactions

by Vitamin World

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Probiotic 10 Premium is a dietary supplement by Vitamin World with 10 active ingredients. Its ingredients are commonly taken for digestive health, lactose digestion support, diarrhea.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus bulgaricus Lb-87, Lactobacillus acidophilus LA14. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Probiotic 10 Premium by Vitamin World

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 10 active ingredients.
  • “Proprietary Probiotic Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

Probiotic 10 Premium has 10 active probiotic strains: Lactobacillus casei, Lactobacillus salivarius, Lactobacillus bulgaricus, Lactobacillus brevis, Bifidobacterium lactis, Lactobacillus paracasei (two different strains), Lactobacillus acidophilus, Lactobacillus plantarum (two different strains), and a proprietary blend. These are live, active bacteria meant to support your gut flora.

The capsule also contains inactive ingredients — dicalcium phosphate, vegetable cellulose, silica, and vegetable magnesium stearate — which are fillers and binders that help form and stabilize the capsule.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Antibiotic-associated diarrhea — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).
  • On file: Bacterial vaginosis — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).
  • On file: Helicobacter pylori — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).
  • On file: Irritable bowel syndrome (IBS) — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).

The evidence for most of these strains isn't established in our data. For Lactobacillus acidophilus specifically, the data shows it's possibly effective for irritable bowel syndrome (IBS), Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis.

It's rated possibly ineffective for atopic disease (allergic conditions). For the other strains — including Lactobacillus bulgaricus — the evidence we hold doesn't support a rating for their use.

The evidence, ingredient by ingredient Lactobacillus Delbrueckii Lactobacillus Acidophilus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus acidophilus is generally well tolerated in healthy adults and children. However, since these are live microorganisms, there's a theoretical concern they could cause infection in people who are very ill or have a weakened immune system — if that's you, check with your doctor first.

Gastrointestinal side effects like abdominal discomfort, bloating, flatulence, and diarrhea can occur when taking a combination of probiotics, though they're uncommon. In one trial, a rash and itching were reported, though it's unclear whether they were caused by the probiotics or other factors.

Side effects, ingredient by ingredient Lactobacillus Delbrueckii Lactobacillus Acidophilus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Lactobacillus Acidophilus, Lactobacillus Delbrueckii.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take Probiotic 10 Premium, check your antibiotic medications with your doctor or pharmacist. Taking antibiotics at the same time as this product may reduce how well the probiotic works.

You may need to separate them by several hours or take them at different times of day.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help with IBS, antibiotic-associated diarrhea, bacterial vaginosis, and H. pylori — though evidence is modest. If you're very ill, immunocompromised, or pregnant, talk with your doctor or pharmacist first.

The biggest thing to watch: if you're taking antibiotics, space them apart from this supplement so the antibiotics don't kill the beneficial bacteria.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 10 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 23, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Probiotic 10 Premium, straight from the product label.

Brand Vitamin World
Barcode (UPC) 766443586470
Net contents 60 Rapid Release Capsule(s)
Market status On market
Date entered into DSLD Dec 23, 2016
DSLD ID 69020
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Probiotic 10 Premium by Vitamin World, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
766443586470
IngredientAmount% DV
Lactobacillus casei Lc-110 NP--
Lactobacillus salivarius Ls-330 NP--
Lactobacillus bulgaricus Lb-870 NP--
Lactobacillus brevis Lbr-350 NP--
Bifidobacterium lactis Bl-040 NP--
Lactobacillus paracasei Lpc-370 NP--
Lactobacillus acidophilus LA140 NP--
Lactobacillus plantarum 299v0 NP--
Lactobacillus paracasei DSM 134340 NP--
Lactobacillus plantarum DSM 153120 NP--
Proprietary Probiotic Blend0 NP--

Other ingredients: Dicalcium Phosphate, Vegetable Cellulose, Silica, Vegetable Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

Quality Assured

Brand IP Statement(s)

At Vitamin World we ensure the quality of all of our premium nutritional products, every step of the way. Strict quality analysis at world-class facilities guarantees that all Vitamin World products are at the highest standard of potency and purity.

Lp299v and probi•digestis are registered trademarks of Probi AB 20 billion active cultures per serving guaranteed at time of manufacture

2016 Vitamin World, Inc.

Nutrition from the source

For those seeking an intestinal health supplement that contains a wide range of probiotics, Probiotic 10 Premium is an excellent choice. This product provides strains clinically studied for optimal maintenance of the digestive and immune systems.

Probi-digestis fist in probiotics

Formulation

No Artificial Color, Flavor or Sweetener, no Preservatives, no Sugar, no Starch, no Milk, no Lactose, no Gluten, no Wheat, no Fish. Sodium free.

Suitable for Vegetarians

Precautions

Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Do not use if seal under cap is broken or missing. Refrigerate after opening.

Contains soy ingredients.

Storage

Store unopened container at room temperature.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

To reorder prod. #58647 www.vitaminworld.com 1-800-228-4533

With clinically studied strains for digestive and immune health

Contains 20 billion live probiotic cultures

-Advanced support for digestive & intestinal health -Supports healthy immune function

Probiotic 10 Premium is a proprietary blend of 20 billion live cultures  from 10 naturally derived strains. Probiotics naturally aid in maintaining the healthy balance of intestinal flora, while supporting the healthy functioning of the intestinal system. For those seeking an intestinal health supplement that contains a wide range of probiotics, Probiotic 10 Premium is an excellent choice. This product provides strains clinically studied for optimal maintenance of the digestive and immune systems.

General

PROD. #58647 B67081 01B

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: For adults, take two (2) capsules daily, preferably with a meal.

Formula

Contains soy ingredients.

See for yourself

Probiotic 10 Premium by Vitamin World label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Probiotic 10 Premium by Vitamin World

These are the 10 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Probiotic Blend

0 NP per serving
  • › Lactobacillus casei Lc-11
  • › Lactobacillus salivarius Ls-33
  • Lactobacillus bulgaricus Lb-87
  • › Lactobacillus brevis Lbr-35
  • › Bifidobacterium lactis Bl-04
  • › Lactobacillus paracasei Lpc-37
  • Lactobacillus acidophilus LA14
  • › Lactobacillus plantarum 299v
  • › Lactobacillus paracasei DSM 13434
  • › Lactobacillus plantarum DSM 15312

Other (inactive) ingredients: Dicalcium Phosphate, Vegetable Cellulose, Silica, Vegetable Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Probiotic 10 Premium by Vitamin World Drug Interactions

Want to check YOUR meds against Probiotic 10 Premium?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Probiotic 10 Premium with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Lactobacillus bulgaricus Lb-871 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L. delbrueckii.
Lactobacillus delbrueckii preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. delbrueckii preparations by at least two hours.

Likelihood Probable Evidence D

Lactobacillus acidophilus LA141 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Probiotic 10 Premium, from the product label.

Vitamin World

See all Vitamin World products
Name
Vitamin World, Inc.
City
Holbrook
State
NY
ZipCode
11741
Phone Number
1-800-228-4533
Web Address
www.vitaminworld.com
Pharmacist Counseling Corner

Probiotic 10 Premium by Vitamin World: Common Questions

Does Probiotic 10 Premium by Vitamin World interact with any medications?
Yes. Based on its ingredients, Probiotic 10 Premium has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Probiotic 10 Premium contains 10 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
Lactobacillus acidophilus is rated possibly safe in pregnancy, but safety data for probiotics as a whole in pregnancy isn't well studied. Talk with your doctor before starting — they can advise based on your situation.
What does this product actually do?
It contains live probiotic bacteria meant to support your gut health. The evidence is strongest for irritable bowel syndrome, antibiotic-associated diarrhea, bacterial vaginosis, and H. pylori infection — though we don't have enough data yet on most of the other strains in this formula.
Are there any common side effects?
Uncommon, but possible: bloating, gas, abdominal discomfort, or mild diarrhea when you first start. A rash or itching has been reported in at least one trial, though it's unclear if it was from the probiotics or something else.
Should I be concerned if I'm immunocompromised?
Yes — check with your doctor first. People who are very ill or have a weakened immune system should use probiotics only under medical guidance, since live bacteria carry a theoretical risk of infection.
What's in the capsule besides the probiotics?
The inactive ingredients are dicalcium phosphate, vegetable cellulose, silica, and vegetable magnesium stearate — fillers and binders that help hold the capsule together.
Can I take this while on antibiotics?
The antibiotics may kill the live bacteria in this supplement, reducing its effectiveness. Talk with your pharmacist about spacing them apart — you might take one in the morning and the other several hours later, or on different schedules.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Probiotic 10 Premium is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Probiotic 10 Premium label
Sources

Sources & How We Checked

Probiotic 10 Premium's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 24 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Delbrueckii 9 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  3. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
  4. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
  5. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
  6. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.
  7. Neonakis IK, Skamagkas I, Stafylaki D, Maraki S. Lactobacillus delbrueckii urinary tract infection in a male patient: a case report. Germs 2022;12(2):304-307. PubMed
  8. Maillet F, Passeron A, Podglajen I, Ranque B, Pouchot J. Lactobacillus delbrueckii urinary tract infection in a male patient. Med Mal Infect 2019;49(3):226-228. PubMed
  9. Darbro BW, Petroelje BK, Doern GV. Lactobacillus delbrueckii as the cause of urinary tract infection. J Clin Microbiol 2009;47(1):275-7.

See these in context on the Lactobacillus Delbrueckii monograph →

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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