Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Probiotic 5M Ingredients & Drug Interactions

by KiddieMax

Probiotic 5M label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Probiotic 5M against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Probiotic 5M is a dietary supplement by KiddieMax with 4 active ingredients. Its ingredients are commonly taken for hair growth and thinning hair, brittle nails, skin health.Based on those ingredients, 188 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus acidophilus, Bifidobacterium bifidum, Apple Pectin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Probiotic 5M by KiddieMax

Ask about any prescription or over-the-counter medication and we check it for interactions with Probiotic 5M by KiddieMax — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Probiotic 5M by KiddieMax

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Probiotic 5M contains four active ingredients. Biotin is a B vitamin that supports skin and nail health.

The product also includes two live probiotic bacteria — Lactobacillus acidophilus and Bifidobacterium bifidum — which work in your gut to support digestive and immune function. Apple Pectin, a soluble fiber from apples, rounds out the blend.

The powder form also contains several inactive ingredients including mannitol, silicon dioxide, calcium carbonate, and digestive enzymes (bromelain, papain, lipase, amylase, and protease), along with sweeteners and gums.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Digestive health and gut balance.
  • We looked for evidence on: Antibiotic-associated diarrhea, Bacterial vaginosis, Clostridioides difficile infection, Colic, Constipation, Diarrhea — and 4 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Bacterial vaginosis, Irritable bowel syndrome (IBS).
  • Also on file: Bifidobacterium Bifidum is rated "Possibly Effective" for Irritable bowel syndrome (IBS).

For biotin, the evidence shows it's likely effective for biotin deficiency — the most straightforward use. For other conditions like multiple sclerosis or seborrheic dermatitis, the data suggests it's possibly ineffective, and for hair loss (alopecia areata), there isn't enough reliable evidence to rate it.

The two probiotic bacteria — Lactobacillus acidophilus and Bifidobacterium bifidum — are possibly effective for irritable bowel syndrome and possibly effective for supporting recovery from antibiotic-related diarrhea. L. acidophilus may also help with bacterial vaginosis and H. pylori, while B. bifidum shows some evidence for respiratory tract infections.

Apple Pectin is possibly effective for high cholesterol but the evidence for blood sugar control is insufficient. Overall, this is a gut-health–focused product, not a treatment for disease.

The evidence, ingredient by ingredient Biotin Lactobacillus Acidophilus Bifidobacterium Bifidum Pectin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Biotin is generally well tolerated, even at higher doses, because your body excretes excess in urine. High-dose biotin has rarely caused mild diarrhea, and one isolated case report linked high-dose biotin with chest inflammation, though it's unclear what caused it.

The two probiotic bacteria are generally well tolerated in healthy people, though those with weakened immune systems should check with their doctor first. Gastrointestinal side effects like gas, bloating, and mild stomach discomfort can occur when taking probiotics, but these are uncommon.

Apple Pectin is generally well tolerated from food and typical amounts, though diarrhea, gas, and mild cramping are possible. Rarely, people sensitive to pectin may have allergic reactions, including anaphylaxis.

For pregnancy, biotin is likely safe at normal amounts. Both Lactobacillus acidophilus and Bifidobacterium bifidum are possibly safe in pregnancy, though safety data are limited.

Apple Pectin is likely safe in normal food amounts but possibly safe in concentrated supplement form during pregnancy — talk to your doctor about high-dose use. Breastfeeding safety data for pectin supplements specifically are limited.

Side effects, ingredient by ingredient Biotin Lactobacillus Acidophilus Bifidobacterium Bifidum Pectin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 4 matched ingredients can interact with medications — Pectin, Lactobacillus Acidophilus, Bifidobacterium Bifidum.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: heart-rhythm medications.
  • For scale: 188 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications against these drug types before starting: first, any heart rhythm medication like digoxin (Lanoxin), because Apple Pectin can reduce its absorption by a significant amount (Moderate severity); second, tetracycline antibiotics and any other antibiotic drugs, which can interact with both the pectin and the live probiotic bacteria (Moderate severity); and third, lovastatin (Mevacor) or other cholesterol medications, where pectin may reduce effectiveness (Moderate severity).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is designed for families wanting to support digestive health with probiotics and biotin. If you take heart medications, antibiotics, or cholesterol drugs, you must check your exact medications before starting, because Apple Pectin can interfere with absorption.

If you're taking antibiotics, time your doses several hours apart from this product so the live bacteria aren't killed. Talk to your pharmacist before use if you have a weakened immune system or are pregnant.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Probiotic 5M, straight from the product label.

Brand KiddieMax
Barcode (UPC) 753406264025
Net contents 2 Ounce(s); 57 Gram(s)
Market status On market
Date entered into DSLD Jan 23, 2025
DSLD ID 323811
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Probiotic 5M by KiddieMax, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Gram(s)
Maximum serving Sizes:
1 Gram(s)
Servings per container
57
UPC/BARCODE
753406264025
IngredientAmount% DV
Calories1 Calorie(s)2%
Total Carbohydrates0.9 Gram(s)2%
Biotin200 mcg67%
Lactobacillus acidophilus7.15 mg--
Bifidobacterium bifidum10 mg--
Sugar Alcohol0.9 Gram(s)--
Apple Pectin5 mg--

Other ingredients: Mannitol, Silicon Dioxide, Calcium Carbonate, Bromelain, Papain, Lipase, Amylase, Protease, Silica, Sucralose, Dextrose, Maltodextrin, Sodium Citrate, Acacia Gum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Mix one (1) heaping scoop with 4 oz. of water, twice daily, or as directed.

Storage

Store tightly closed, refrigerate after opening for maximum potency.

Keep tightly closed in a cool, dry place.

Precautions

Keep out of reach of children.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Vegetarian

Digestion & absorption Yeast

This product contains no animal products, soy, wheat, gluten, yeast, milk, salt, artificial flavors, colorings or preservatives.

This product was manufactured in a NSF GMP Certified facility.

Immune boost Hair skin & nails

Formula

Certified Kosher UK (Rav Shmuel Dovid Krausz (Udvarer Rav)) (Kosher) BDZ Edah Charedis - Orthodox Council of Jerusalem (Kosher)

Enzymax Base

General Statements

Doctor Formulated

More wellness from every bite

Seals/Symbols

UK (Rav Shmuel Dovid Krausz (Udvarer Rav)) (Kosher) BDZ Edah Charedis - Orthodox Council of Jerusalem (Kosher)

OU (Kosher)

Manufactured in a Certified GMP facility

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Enzymax, a vital digestive enzyme complex, is a registered trademark of Maxi health Research LLC.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Probiotic 5M by KiddieMax label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Probiotic 5M label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Probiotic 5M by KiddieMax

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Gram(s) Dosage formPowder Servings per container57 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Biotin

No known
interactions
200 mcg per serving

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...

Biotin monograph & interactions

Lactobacillus acidophilus

Interacts with
182 drugs
7.15 mg per serving

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy p...

Lactobacillus acidophilus monograph & interactions

Bifidobacterium bifidum

Interacts with
182 drugs
10 mg per serving

Bifidobacterium bifidum is a 'friendly' bacteria (probiotic) that naturally lives in the human gut and is taken to support digestion and gut balance....

Bifidobacterium bifidum monograph & interactions

Apple Pectin

Interacts with
23 drugs
5 mg per serving Form: Malus domestica

Pectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly he...

Apple Pectin monograph & interactions

Other (inactive) ingredients: Mannitol, Silicon Dioxide, Calcium Carbonate, Bromelain, Papain, Lipase, Amylase, Protease, Silica, Sucralose, Dextrose, Maltodextrin, Sodium Citrate, Acacia Gum. These complete the product’s ingredient list but are not active constituents.

Interaction report

Probiotic 5M by KiddieMax Drug Interactions

Want to check YOUR meds against Probiotic 5M?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
188Drugs
188 Moderate

Ingredients driving the most interactions

Lactobacillus acidophilus 182
Bifidobacterium bifidum 182
Apple Pectin 23

Individual Drug Interactions

The ingredients in Probiotic 5M interact with 188 drugs. Click any drug to see the details.

3 of the 4 ingredients in Probiotic 5M interact with drugs. Each result below shows which ingredient is responsible. Lactobacillus acidophilus Bifidobacterium bifidum Apple Pectin

Each ingredient & the kinds of drugs it affects

For each ingredient in Probiotic 5M with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Lactobacillus acidophilus1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus acidophilus full monograph & interactions

Bifidobacterium bifidum1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium. bifidum with antibiotic drugs might decrease the effectiveness of B. bifidum.
Since B. bifidum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. bifidum preparations by at least 2 hours.

Likelihood Probable Evidence D
Bifidobacterium bifidum full monograph & interactions

Apple Pectin3 drug types · 23 drugs

Digoxin (Lanoxin)

Theoretically, pectin might reduce the absorption of digoxin, potentially decreasing its effectiveness.
A small clinical study shows that taking digoxin with a kaolin-pectin suspension reduces the absorption of digoxin by about 62%. It is unclear if these effects are due to pectin, kaolin, or the combination.

Likelihood Possible Evidence B
Lovastatin (Mevacor)

Theoretically, pectin might reduce the absorption of lovastatin, potentially decreasing its effectiveness.
Case reports suggest that concomitant use of pectin and lovastatin might reduce the cholesterol-lowering effect of lovastatin, possibly due to reduced intestinal absorption of lovastatin.

Likelihood Possible Evidence D
Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
A small clinical study shows that taking tetracycline with bismuth subsalicylate in a kaolin-pectin suspension reduces the absorption of tetracycline by about 34%. It is unclear if these effects are due to pectin, kaolin, bismuth subsalicylate, or the combination.

Likelihood Possible Evidence B
Apple Pectin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Probiotic 5M, from the product label.

KiddieMax

See all KiddieMax products
Name
Maxi Health
City
Brooklyn
State
N.Y.
Phone Number
800-544-6294
Web Address
www.maxihealth.com
Pharmacist Counseling Corner

Probiotic 5M by KiddieMax: Common Questions

Does Probiotic 5M by KiddieMax interact with any medications?
Yes. Based on its ingredients, Probiotic 5M has a known interaction with 188 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Probiotic 5M contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe for my child?
Probiotic 5M is a powder designed for kids. The probiotics and biotin are generally well tolerated in children. However, you may notice mild gas, bloating, or loose stools when starting — these are usually uncommon but can happen. If your child has a weakened immune system or is on antibiotics, talk to your pediatrician or pharmacist first.
Can I take this while my child is on antibiotics?
The probiotics in this product are live bacteria, and antibiotics will kill them. If possible, separate doses by at least a few hours — take the antibiotic at one time of day and the probiotic at another. Your pharmacist can help you time the doses to protect the probiotics.
What does biotin do in this product?
Biotin is a B vitamin that supports healthy skin, hair, and nails. This product uses it as a supplement to dietary biotin. The evidence shows it's likely effective for actual biotin deficiency, though for other conditions like hair loss the evidence is weaker.
Will this help with my child's digestive problems?
The two probiotic strains — Lactobacillus acidophilus and Bifidobacterium bifidum — are possibly effective for irritable bowel syndrome and for diarrhea caused by antibiotics. These probiotics work by supporting healthy gut bacteria, but results vary by person. Talk to your pediatrician about whether probiotics are right for your child's specific situation.
Are there any serious side effects I should watch for?
Most people tolerate this product well. The most common side effects are mild gas, bloating, or loose stools, especially when starting. Serious allergic reactions to pectin are very rare. If your child develops a rash, itching, or any signs of an allergic reaction, stop and contact your doctor right away.
Is it safe to give this to my pregnant or breastfeeding child?
This product is designed for children, not pregnant or breastfeeding individuals — if you're asking about yourself, talk to your doctor. Biotin is likely safe in pregnancy at normal amounts. The probiotic bacteria are possibly safe but data are limited, and pectin safety in concentrated supplements during pregnancy hasn't been well studied.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Probiotic 5M is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Probiotic 5M label
Go deeper

The Full Monographs Behind Probiotic 5M’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Biotin

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get plenty from a normal diet, and true defi...

Read the full Biotin monograph → Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph → Herb & supplement monograph

Bifidobacterium Bifidum

Interacts with 182 drugs

Bifidobacterium bifidum is a 'friendly' bacteria (probiotic) that naturally lives in the human gut and is taken to support digestion and gut balance. Some evidence suggests probiotics may he...

Read the full Bifidobacterium Bifidum monograph → Herb & supplement monograph

Pectin

Interacts with 23 drugs

Pectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly help with cholesterol, blood sugar, and di...

Read the full Pectin monograph →
Sources

Sources & How We Checked

Probiotic 5M's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 37 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Biotin 4 references
  1. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
  4. Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed

See these in context on the Biotin monograph →

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Bifidobacterium Bifidum 7 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  3. Rerksuppaphol S, Rerksuppaphol L. Randomized controlled trial of probiotics to reduce common cold in schoolchildren. Pediatr Int. 2012;54(5):682-7. PubMed
  4. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  5. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  6. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  7. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed

See these in context on the Bifidobacterium Bifidum monograph →

Pectin 11 references
  1. Jaakkola MS, et al. Asthma caused by occupational exposure to pectin. J Allergy Clin Immunol 1997;100:575-6. PubMed
  2. Westphal W, et al. [Exogenous allergic asthma following pectin exposure-a new occupational allergen]. Pneumologie 1990;44(Suppl 1):337-8.
  3. Baldwin JL, et al. Pectin-induced occupational asthma. Chest 1993;104:1936-7. PubMed
  4. Cohen AJ, Forse MS, Tarlo SM. Occupational asthma caused by pectin inhalation during the manufacture of jam. Chest 1993;103:309-11.
  5. Kraut A, et al. Christmas candy maker's asthma. IgG4-mediated pectin allergy. Chest 1992;102:1605-7. PubMed
  6. Richter WO, Jacob BG, Schwandt P. Interaction between fibre and lovastatin. Lancet 1991;338:706.
  7. Albert KS, Ayres JW, DiSanto AR, et al. Influence of kaolin-pectin suspension on digoxin bioavailability. J Pharm Sci 1978;67:1582-6. PubMed
  8. Albert KS, Welch RD, DeSante KA, et al. Decreased tetracycline bioavailability caused by a bismuth subsalicylate antidiarrheal mixture. J Pharm Sci 1979;68:586-8. PubMed
  9. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  10. Federal Register April 17,2003. Anti-Diarrheal Products for over-the-counter human use; final monograph. Available at: http://www.fda.gov/OHRMS/DOCKETS/98fr/03-9380.pdf (Accessed 27 December 2004).
  11. Washio K, Nakamura M, Sato N, et al. Anaphylaxis in a pectin- and cashew nut-allergic child caused by a citrus bath. Allergol Int 2022;71(1):155-157. PubMed

See these in context on the Pectin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team