Interactions on record — worth a quick check against your medications. Based on 2 of 4 ingredients. Check your meds →
Dietary supplement

Probiotic + Prebiotic Ingredients & Drug Interactions

by Hero Nutritionals Yummi Bears

Probiotic + Prebiotic label
See full label image
Gummy Or Jelly Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Probiotic + Prebiotic against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Probiotic + Prebiotic is a dietary supplement by Hero Nutritionals Yummi Bears with 4 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,083 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, B. coagulans probiotic. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Probiotic + Prebiotic by Hero Nutritionals Yummi Bears

Ask about any prescription or over-the-counter medication and we check it for interactions with Probiotic + Prebiotic by Hero Nutritionals Yummi Bears — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Probiotic + Prebiotic by Hero Nutritionals Yummi Bears

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 2 of its 3 active ingredients.

This gummy contains 3 active ingredients: soluble fiber, B. coagulans (a probiotic strain), and prebiotic fiber. The probiotic is a live microorganism designed to support your gut; the prebiotic fiber acts as food for beneficial bacteria.

The rest is flavoring, sweeteners, gelatin, pectin, and other inactive ingredients that make the gummy taste and feel right.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: supports digestion and immune health.
  • We looked for evidence on: Antibiotic-associated diarrhea, Constipation, Diarrhea, Dyspepsia, Flatulence, Inflammatory bowel disease (IBD) — and 4 related terms.
  • The strongest evidence on file: Black Psyllium is rated "Effective" for Constipation (Natural Medicines).
  • Also on file: Bacillus Coagulans is rated "Possibly Effective" for Constipation, Irritable bowel syndrome (IBS).
  • Also on file: Black Psyllium is rated "Insufficient Reliable Evidence To Rate" for Diarrhea.

B. coagulans has some evidence behind it. The data shows it's possibly effective for constipation and irritable bowel syndrome (IBS).

For other uses listed — antibiotic-associated diarrhea, athletic performance, cancer, and nonalcoholic fatty liver disease — we don't have enough reliable evidence to say whether it works. We hold no effectiveness data on the soluble fiber or prebiotic fiber ingredients in this product.

The evidence, ingredient by ingredient Black Psyllium Bacillus Coagulans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

B. coagulans is generally well tolerated in healthy adults, but the evidence and quality of probiotic products vary — so talk to your doctor before starting, especially if you're not sure it's right for you. There's limited safety information overall, and we'd suggest checking with your pharmacist first.

One important note: because this product contains live organisms, there's a theoretical concern they could cause serious infection in people with severely weakened immune systems, central venous catheters, or severe illness — but this is uncommon in otherwise healthy people. We don't have pregnancy and lactation safety data on file for this product.

Side effects, ingredient by ingredient Black Psyllium Bacillus Coagulans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Black Psyllium, Bacillus Coagulans.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: heart-rhythm medications; lithium.
  • For scale: 2,084 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antibiotics, double-check the timing before starting this product — the probiotic could lose effectiveness if you take them at the same time. We couldn't check interaction data for the fiber ingredients, so use the medication checker on this page to be sure your exact drugs are clear.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This might be worth considering if you're dealing with constipation or IBS and want to try a probiotic with some evidence behind it. If you take antibiotics, separate the timing — don't take them together.

Anyone with a weakened immune system, severe illness, or a central line should check with their doctor first. Run your medications through our interaction checker before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 21, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Probiotic + Prebiotic, straight from the product label.

Brand Hero Nutritionals Yummi Bears
Net contents 60 Yummi Bear(s)
Market status On market
Date entered into DSLD Jul 21, 2022
DSLD ID 268221
Product type Other Combinations
Supplement form Gummy Or Jelly
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Children (All), No Allergies, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Probiotic + Prebiotic by Hero Nutritionals Yummi Bears, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Bear(s)
Maximum serving Sizes:
2 Bear(s)
Servings per container
30
IngredientAmount% DV
Calories15 Calorie(s)--
Total Carbohydrates4 Gram(s)--
Sugar1 Gram(s)--
Dietary Fiber1 Gram(s)--
Fiber, Soluble1 Gram(s)--
B. coagulans probiotic0 NP--
Prebiotic Fiber1000 mg--

Other ingredients: Pineapple, Glucose Syrup, Cane Sugar, Gelatin, Sodium Citrate, Citric Acid, Natural Flavors, Natural colors, Pectin, Coconut Oil, Fractionated, Carnauba Wax

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

New look!

Actual size and serving:

Gummy product may settle over time.

Questions or comments? 800.500.HERO (4376) 8am-4pm, M-F, PST heronutritionals.com

Our passion continues in providing essential nutrients for the whole family, with Yummi Slices Adult Gummy Vitamins - a wide range of nutritional support for adults, in delicious, easy to take gummies.

Brand IP Statement(s)

The Original Gummy Vitamin

Pure love deserves pure nutrition The original gummy vitamin for over 20 years

Formulation

New flavors, in a 3-bear dose! Supports digestion and immune health

Non GMO Allergen free Gluten free Dairy free Soy free

Free of: Gluten, yeast, wheat, dairy, eggs, soy, peanuts, shellfish, fish, artificial flavors, artificial colors and artificial preservatives.

Product appearance may change over time due to colors from fruits and vegetables. This does not alter the potency of the product.

Yummi Bears and Yummi Slices gummy vitamins are made in our state-of-the-art, certified organic facility in California, so you can be assured you are getting the best quality.

Formula

Made with real pineapple juice 4 billion active probiotics

Yummi Bears Probiotic + Prebiotic is infused with 4 billion active probiotics and 1000 mg of prebiotics per serving to help promote digestive health and immunity. Made with real pineapple juice for a naturally delicious yummi gummy.

4B probiotic 1000mg prebiotic fiber

For over 20 years we've been making Yummi Bears - The Original Gummy Vitamin formulated just for kids.

And because you care about what goes into your kids, we care about what goes into our gummies: natural fruit flavors, colors and sweeteners - plus they're non-GMO, allergen and gluten free.

FDA Disclaimer Statement

Dietary Supplement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

And no refrigeration required!

Store in a cool, dry place. Do not use if safety seal is broken. Keep sealed for freshness.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, give each child two (2) bears per day.

Precautions

Keep out of reach of children.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Probiotic + Prebiotic by Hero Nutritionals Yummi Bears label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Probiotic + Prebiotic label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Probiotic + Prebiotic by Hero Nutritionals Yummi Bears

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Bear(s) Dosage formGummy Or Jelly Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

1 Gram(s) per serving

Dietary Fiber

Interacts with
2,025 drugs
1 Gram(s) per serving

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...

Dietary Fiber monograph & interactions
  • › Fiber, Soluble

B. coagulans probiotic

Interacts with
182 drugs
0 NP per serving

Bacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, a...

B. coagulans probiotic monograph & interactions

Prebiotic Fiber

1000 mg per serving

Other (inactive) ingredients: Pineapple, Glucose Syrup, Cane Sugar, Gelatin, Sodium Citrate, Citric Acid, Natural Flavors, Natural colors, Pectin, Coconut Oil, Fractionated, Carnauba Wax. These complete the product’s ingredient list but are not active constituents.

Interaction report

Probiotic + Prebiotic by Hero Nutritionals Yummi Bears Drug Interactions

Want to check YOUR meds against Probiotic + Prebiotic?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,083Drugs
205 Moderate 1,878 Minor

Ingredients driving the most interactions

Dietary Fiber 2,025
B. coagulans probiotic 182

Individual Drug Interactions

The ingredients in Probiotic + Prebiotic interact with 2,083 drugs. Click any drug to see the details.

2 of the 4 ingredients in Probiotic + Prebiotic interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber B. coagulans probiotic

Each ingredient & the kinds of drugs it affects

For each ingredient in Probiotic + Prebiotic with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dietary Fiber7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B
Dietary Fiber full monograph & interactions

B. coagulans probiotic1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B. coagulans.
B. coagulans preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. coagulans preparations by at least two hours.

Likelihood Probable Evidence D
B. coagulans probiotic full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Probiotic + Prebiotic, from the product label.

Hero Nutritionals Yummi Bears

See all Hero Nutritionals Yummi Bears products
Name
Hero Nutritionals, Inc.
City
Santa Ana
State
CA
ZipCode
92705
Phone Number
800.500.4376
Web Address
www.heronutritionals.com
Pharmacist Counseling Corner

Probiotic + Prebiotic by Hero Nutritionals Yummi Bears: Common Questions

Does Probiotic + Prebiotic by Hero Nutritionals Yummi Bears interact with any medications?
Yes. Based on its ingredients, Probiotic + Prebiotic has a known interaction with 2,083 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Probiotic + Prebiotic contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my irritable bowel syndrome?
B. coagulans in this product is possibly effective for IBS based on the evidence we hold — but 'possibly' means the data is promising, not guaranteed. Everyone's different, so it's worth a conversation with your doctor about whether it makes sense for your situation.
Can I take this while I'm on antibiotics?
Not at the same time. Antibiotics kill the live organisms in the probiotic, so it won't work as well. Ask your pharmacist to help you space them out — usually a few hours apart is enough.
Is this safe if I'm pregnant or breastfeeding?
We don't have safety data on file for pregnancy or lactation with this product. Talk with your doctor or pharmacist before using it — they can give you personalized advice based on your situation.
What's inside these gummies besides the probiotic?
You get soluble fiber and prebiotic fiber along with B. coagulans. The rest is inactive — flavoring, sweeteners like glucose syrup and cane sugar, gelatin, pectin, coconut oil, and colors to make them look and taste good.
Are there any side effects I should know about?
B. coagulans is generally well tolerated, but since it's a live organism, there's a small theoretical risk of serious infection in people with very weak immune systems or severe illness — rare in healthy people. Most folks have no trouble with it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Probiotic + Prebiotic is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Probiotic + Prebiotic label
Go deeper

The Full Monographs Behind Probiotic + Prebiotic’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Black Psyllium

Interacts with 2,025 drugs

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...

Read the full Black Psyllium monograph → Herb & supplement monograph

Bacillus Coagulans

Interacts with 182 drugs

Bacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, and certain types of diarrhea. The eviden...

Read the full Bacillus Coagulans monograph →
Sources

Sources & How We Checked

Probiotic + Prebiotic's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 38 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Psyllium 18 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  4. Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
  5. Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
  6. Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
  7. Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
  8. Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
  9. Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
  10. Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
  11. Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
  12. Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
  13. Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
  14. Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
  15. Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
  16. Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
  17. Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
  18. Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed

See these in context on the Black Psyllium monograph →

Bacillus Coagulans 20 references
  1. Saxelin M, Chuang NH, Chassy B, et al. Lactobacilli and bacteremia in southern Finland 1989-1992. Clin Infect Dis 1996;22:564-6. PubMed
  2. Tynkkynen S, Singh KV, Varmanen P. Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes. Int J Food Microbiol 1998;41:195-204. PubMed
  3. Klein G, Zill E, Schindler R, et al. Peritonitis associated with vancomycin-resistant Lactobacillus rhamnosus in a continuous ambulatory peritoneal dialysis patient; organism identification, antibiotic therapy, and case report. J Clin Microbiol 1998;36:
  4. Kalima P, Masterton RG, Roddie PH, et al. Lactobacillus rhamnosus infection in a child following bone marrow transplant. J Infect 1996;32:165-7. PubMed
  5. Goldin BR. Health Benefits of probiotics. Br J Nutr 1998;80:S203-7. DOI
  6. Rautio M, Jousimies-Somer H, Kauma H, et al. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. Clin Infect Dis 1999;28:1159-60.
  7. MacGregor G, Smith AJ, Thakker B, Kinsella J. Yoghurt biotherapy: contraindicated in immunosuppressed patients? Postgrad Med J 2002;78:366-7. PubMed
  8. Land MH, Rouster-Stevens K, Woods CR, et al. Lactobacillus sepsis associated with probiotic therapy. Pediatrics 2005;115:178-81.
  9. De Groote MA, Frank DN, Dowell E, et al. Lactobacillus rhamnosus GG bacteremia associated with probiotic use in a child with short gut syndrome. Pediatr Infect Dis J 2005;24:278-80. PubMed
  10. Vahabnezhad E, Mochon AB, Wozniak LJ, Ziring DA. Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis. J Clin Gastroenterol. 2013;47(5):437-9. PubMed
  11. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  12. Sendil S, Shrimanker I, Mansoora Q, Goldman J, Nookala VK. Lactobacillus rhamnosus bacteremia in an immunocompromised renal transplant patient. Cureus. 2020;12(2):e6887. PubMed
  13. Albarillo FS, Shah U, Joyce C, Slade D. Lactobacillus rhamnosus Infection: A single-center 4-year descriptive analysis. J Glob Infect Dis. 2020;12(3):119-123. PubMed
  14. Pasala S, Singer L, Arshad T, Roach K. Lactobacillus endocarditis in a healthy patient with probiotic use. IDCases. 2020;22:e00915. PubMed
  15. Agrawal S, Tuchman ES, Bruce MJ, Theodorou ME. Fatal Lactobacillus endocarditis in a patient with transcatheter aortic valve replacement. BMJ Case Rep. 2020;13(11):e236835.
  16. Antoun M, Hattab Y, Akhrass FA, Hamilton LD. Uncommon pathogen, Lactobacillus, causing infective endocarditis: Case report and review. Case Rep Infect Dis. 2020;2020:8833948. PubMed
  17. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  18. Franko B, Vaillant M, Recule C, Vautrin E, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics. Med Mal Infect. 2013;43(4):171-3. PubMed
  19. Campbell RE, Miller A, Afroze A. Native valve endocarditis secondary to Lactobacillus paracasei bacteremia. Consultant. 2020;60(9):27-8. DOI
  20. Kato K, Funabashi N, Takaoka H, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics with advanced and severe bicuspid aortic valve stenosis complicated with diffuse left ventricular mid-layer fibrosis. Int J Cardiol. 2016;224:157-161. PubMed

See these in context on the Bacillus Coagulans monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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