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Dietary supplement

Probiotic Progels 10 Billion Ingredients & Drug Interactions

by Meijer

Probiotic Progels 10 Billion label
See full label image
Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Probiotic Progels 10 Billion against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Probiotic Progels 10 Billion is a dietary supplement by Meijer with 1 active ingredient. Its ingredients are commonly taken for constipation, irritable bowel syndrome (ibs), diarrhea.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are ProDURA Bacillus coagulans. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Probiotic Progels 10 Billion by Meijer

Ask about any prescription or over-the-counter medication and we check it for interactions with Probiotic Progels 10 Billion by Meijer — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Probiotic Progels 10 Billion by Meijer

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This product contains one active ingredient: ProDURA Bacillus coagulans, a live probiotic strain. The softgel capsule also contains several inactive ingredients — soybean oil, gelatin, glycerin, beeswax, purified water, soy lecithin, mica, and titanium dioxide — that help hold and protect the live organisms.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: General digestive and gut health.
  • We looked for evidence on: Constipation, Irritable bowel syndrome (IBS), Flatulence, Dyspepsia, Antibiotic-associated diarrhea, Travelers' diarrhea — and 4 related terms.
  • The strongest evidence on file: Bacillus Coagulans is rated "Possibly Effective" for Constipation (Natural Medicines).
  • Also on file: Bacillus Coagulans is rated "Possibly Effective" for Irritable bowel syndrome (IBS).
  • Also on file: Bacillus Coagulans is rated "Insufficient Reliable Evidence To Rate" for Antibiotic-associated diarrhea, Diarrhea, Dyspepsia, Flatulence, and more.

Bacillus coagulans is possibly effective for constipation and irritable bowel syndrome (IBS). For other uses — antibiotic-associated diarrhea, athletic performance, cancer support, and fatty liver disease — there isn't enough reliable evidence yet to know whether it works.

If you're considering this for constipation or IBS, talk it over with your doctor to see if it fits your situation.

The evidence, ingredient by ingredient Bacillus Coagulans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bacillus coagulans is generally well tolerated in healthy adults, though the evidence and product quality vary across different brands and batches. The main concern is that live probiotic organisms can theoretically cause infection in people with severely weakened immune systems, central lines (catheters placed in major blood vessels), or very serious illness — but reports of this in otherwise healthy people with intact immune systems are rare.

There isn't enough reliable safety data overall; check with your doctor or pharmacist before starting, especially if you have any chronic health condition or a compromised immune system. Data on pregnancy and breastfeeding safety isn't on file — talk with your doctor about whether it's right for you during these times.

Side effects, ingredient by ingredient Bacillus Coagulans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bacillus Coagulans.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Separate this probiotic from antibiotics — take them several hours apart so the antibiotic doesn't kill off the live organisms in the supplement. If you're on an antibiotic now or about to start one, confirm the timing with your doctor or pharmacist before you begin this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This probiotic is a reasonable option if you're dealing with constipation or IBS and your immune system is intact. Just remember to separate it from any antibiotics you're taking, since they can interfere with each other.

If you're severely ill, immunocompromised, or have a central catheter, check with your doctor first. Talk it over with your own doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Probiotic Progels 10 Billion, straight from the product label.

Brand Meijer
Barcode (UPC) 708820718654
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Aug 23, 2022
DSLD ID 271972
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Probiotic Progels 10 Billion by Meijer, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
60
UPC/BARCODE
708820718654
IngredientAmount% DV
ProDURA Bacillus coagulans0 NP--

Other ingredients: Soybean Oil, Gelatin, Glycerin, White Beeswax, Water, Purified, Soy Lecithin, Mica, Titanium Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Potentially beneficial microflora per softgel At time of manufacture. 3 billion CFUs at time of expiration.

General health

Does not contain milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat or gluten.

Meijer Probiotic ProGels with 10 billion CFUs are remarkably resistant: They contain a very special live beneficial microflora probiotic called ProDURA. While many other probiotics die in the harsh conditions of the stomach, never providing you with their intended benefit, ProDURA survives due to its unique protective coating. Upon meeting the perfect conditions of heat, pH and moisture found in the large intestine, ProDURA probiotic releases out of its protective coating, providing its probiotic benefits.

GF Gluten free

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

This statements has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

This statements has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take one (1) softgel daily.

Precautions

For adults only.

As a reminder, discuss the supplements and medications you take with our health care providers.

Contains: Soy

Warning: If you are pregnant or nursing, taking medications, or if you have any medical condition or are planning any medical procedure, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur. Tamper Evident: Do not use if seal under cap is broken or missing.

Keep out of reach of children.

Brand IP Statement(s)

ProDURA is a registered trademark of UAS Laboratories, LLC.

Storage

For optimal storage conditions, keep in a cool, dry place with the cap tightly closed. Protect from excessive heat or freezing.

General Statements

Individual results may vary.

Questions or comments? 1-800-352-8674

Seals/Symbols

Our quality guarantee The Meijer Family www.meijer.com/satisfaction

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Probiotic Progels 10 Billion by Meijer label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Probiotic Progels 10 Billion label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Probiotic Progels 10 Billion by Meijer

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.

ProDURA Bacillus coagulans

Interacts with
182 drugs
0 NP per serving

Bacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, a...

ProDURA Bacillus coagulans monograph & interactions

Other (inactive) ingredients: Soybean Oil, Gelatin, Glycerin, White Beeswax, Water, Purified, Soy Lecithin, Mica, Titanium Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Probiotic Progels 10 Billion by Meijer Drug Interactions

Want to check YOUR meds against Probiotic Progels 10 Billion?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

ProDURA Bacillus coagulans 182

Individual Drug Interactions

The ingredients in Probiotic Progels 10 Billion interact with 182 drugs. Click any drug to see the details.

1 of the 1 ingredient in Probiotic Progels 10 Billion interact with drugs. Each result below shows which ingredient is responsible. ProDURA Bacillus coagulans

Each ingredient & the kinds of drugs it affects

For each ingredient in Probiotic Progels 10 Billion with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

ProDURA Bacillus coagulans1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B. coagulans.
B. coagulans preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. coagulans preparations by at least two hours.

Likelihood Probable Evidence D
ProDURA Bacillus coagulans full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Probiotic Progels 10 Billion, from the product label.

Meijer

See all Meijer products
Name
Meijer Distribution, Inc.
City
Grand Rapids
State
MI
ZipCode
49544
Phone Number
1-800-352-8674
Web Address
www.meijer.com
Pharmacist Counseling Corner

Probiotic Progels 10 Billion by Meijer: Common Questions

Does Probiotic Progels 10 Billion by Meijer interact with any medications?
Yes. Based on its ingredients, Probiotic Progels 10 Billion has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Probiotic Progels 10 Billion contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my constipation or IBS?
Bacillus coagulans is possibly effective for both constipation and irritable bowel syndrome, based on the available evidence. That means there's some support for it, but it's not a sure thing — results vary from person to person. Talk with your doctor to see if it's worth trying for your specific situation.
What exactly is Bacillus coagulans?
It's a live probiotic bacterium — a 'good' microorganism that can help support digestive health. The ProDURA strain in this product is specifically chosen for that purpose. Like all probiotics, it works best when the organisms stay alive and active in your gut.
Can I take this while I'm on antibiotics?
Not at the same time. Antibiotics kill bacteria, including the live organisms in this probiotic, so taking them together reduces the probiotic's effectiveness. Separate the doses by several hours — your doctor or pharmacist can recommend the right timing for your specific antibiotic.
Is this safe if I have a weakened immune system?
That's something to check with your doctor first. While healthy people generally tolerate this probiotic well, live organisms can theoretically cause infection in people with severely weakened immunity or central lines. Your doctor knows your situation best and can advise you.
What are the side effects?
Most people don't experience problems with Bacillus coagulans, but the evidence on side effects is limited overall. As with any live probiotic, there's a theoretical concern about infection in people with very weak immune systems, though this is uncommon in otherwise healthy people. If you notice unusual symptoms after starting, let your doctor or pharmacist know.
Is it safe to take during pregnancy or breastfeeding?
There isn't enough data on file about this product's safety in pregnancy and breastfeeding. Talk with your doctor or pharmacist — they can help you decide whether it's right for you during these times.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Probiotic Progels 10 Billion is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Probiotic Progels 10 Billion label
Go deeper

The Full Monographs Behind Probiotic Progels 10 Billion’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bacillus Coagulans

Interacts with 182 drugs

Bacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, and certain types of diarrhea. The eviden...

Read the full Bacillus Coagulans monograph →
Sources

Sources & How We Checked

Probiotic Progels 10 Billion's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 20 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bacillus Coagulans 20 references
  1. Saxelin M, Chuang NH, Chassy B, et al. Lactobacilli and bacteremia in southern Finland 1989-1992. Clin Infect Dis 1996;22:564-6. PubMed
  2. Tynkkynen S, Singh KV, Varmanen P. Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes. Int J Food Microbiol 1998;41:195-204. PubMed
  3. Klein G, Zill E, Schindler R, et al. Peritonitis associated with vancomycin-resistant Lactobacillus rhamnosus in a continuous ambulatory peritoneal dialysis patient; organism identification, antibiotic therapy, and case report. J Clin Microbiol 1998;36:
  4. Kalima P, Masterton RG, Roddie PH, et al. Lactobacillus rhamnosus infection in a child following bone marrow transplant. J Infect 1996;32:165-7. PubMed
  5. Goldin BR. Health Benefits of probiotics. Br J Nutr 1998;80:S203-7. DOI
  6. Rautio M, Jousimies-Somer H, Kauma H, et al. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. Clin Infect Dis 1999;28:1159-60.
  7. MacGregor G, Smith AJ, Thakker B, Kinsella J. Yoghurt biotherapy: contraindicated in immunosuppressed patients? Postgrad Med J 2002;78:366-7. PubMed
  8. Land MH, Rouster-Stevens K, Woods CR, et al. Lactobacillus sepsis associated with probiotic therapy. Pediatrics 2005;115:178-81.
  9. De Groote MA, Frank DN, Dowell E, et al. Lactobacillus rhamnosus GG bacteremia associated with probiotic use in a child with short gut syndrome. Pediatr Infect Dis J 2005;24:278-80. PubMed
  10. Vahabnezhad E, Mochon AB, Wozniak LJ, Ziring DA. Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis. J Clin Gastroenterol. 2013;47(5):437-9. PubMed
  11. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  12. Sendil S, Shrimanker I, Mansoora Q, Goldman J, Nookala VK. Lactobacillus rhamnosus bacteremia in an immunocompromised renal transplant patient. Cureus. 2020;12(2):e6887. PubMed
  13. Albarillo FS, Shah U, Joyce C, Slade D. Lactobacillus rhamnosus Infection: A single-center 4-year descriptive analysis. J Glob Infect Dis. 2020;12(3):119-123. PubMed
  14. Pasala S, Singer L, Arshad T, Roach K. Lactobacillus endocarditis in a healthy patient with probiotic use. IDCases. 2020;22:e00915. PubMed
  15. Agrawal S, Tuchman ES, Bruce MJ, Theodorou ME. Fatal Lactobacillus endocarditis in a patient with transcatheter aortic valve replacement. BMJ Case Rep. 2020;13(11):e236835.
  16. Antoun M, Hattab Y, Akhrass FA, Hamilton LD. Uncommon pathogen, Lactobacillus, causing infective endocarditis: Case report and review. Case Rep Infect Dis. 2020;2020:8833948. PubMed
  17. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  18. Franko B, Vaillant M, Recule C, Vautrin E, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics. Med Mal Infect. 2013;43(4):171-3. PubMed
  19. Campbell RE, Miller A, Afroze A. Native valve endocarditis secondary to Lactobacillus paracasei bacteremia. Consultant. 2020;60(9):27-8. DOI
  20. Kato K, Funabashi N, Takaoka H, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics with advanced and severe bicuspid aortic valve stenosis complicated with diffuse left ventricular mid-layer fibrosis. Int J Cardiol. 2016;224:157-161. PubMed

See these in context on the Bacillus Coagulans monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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