Interactions on record — worth a quick check against your medications. Based on 2 of 4 ingredients. Check your meds →
Dietary supplement

Prost-8-Palmetto Ingredients & Drug Interactions

by Montiff

Prost-8-Palmetto label
See full label image
Softgel Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Prost-8-Palmetto against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Prost-8-Palmetto is a dietary supplement by Montiff with 4 active ingredients. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, overactive bladder, eye and skin health (vitamin a source).Based on those ingredients, 175 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Saw Palmetto extract, Pumpkin seed Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Prost-8-Palmetto by Montiff

Ask about any prescription or over-the-counter medication and we check it for interactions with Prost-8-Palmetto by Montiff — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Prost-8-Palmetto by Montiff

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • “{Soft-gel}” is listed as a grouped ingredient — the label gives one combined amount (491.10 mg) without saying how much of each component you get.

Prost-8-Palmetto has 3 active ingredients. Pumpkin seed oil is included for benign prostatic hyperplasia (enlarged prostate) — it's possibly effective for that condition based on the evidence we hold.

Saw palmetto extract is also in the formula; the data suggests it may be ineffective for benign prostatic hyperplasia, though it is possibly effective for a specific prostate procedure called transurethral resection of the prostate (TURP). The product also contains inactive ingredients — gelatin, glycerin, water, carob extract concentrate, and titanium dioxide — which help form and color the softgel capsule.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Prostate health and urinary function.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Non-neurogenic lower urinary tract symptoms (LUTS), Overactive bladder, Prostatitis, Chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS), Urinary flow — and 1 related terms.
  • The strongest evidence on file: Pumpkin is rated "Possibly Effective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).
  • Also on file: Saw Palmetto is rated "Possibly Ineffective" for Benign prostatic hyperplasia (BPH).
  • Also on file: Pumpkin is rated "Insufficient Reliable Evidence To Rate" for Overactive bladder.

For benign prostatic hyperplasia (enlarged prostate), pumpkin seed oil is rated possibly effective, meaning there's some evidence it may help. Saw palmetto, on the other hand, is rated possibly ineffective for this condition based on the current data.

For other uses — hair loss, bladder issues, urinary tract infections, and chronic bronchitis — the evidence in our data is insufficient to rate either ingredient, which means we simply don't have enough reliable information to say whether they work.

The evidence, ingredient by ingredient Pumpkin Saw Palmetto

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both pumpkin seed oil and saw palmetto are generally well tolerated in adults. With pumpkin seed oil, the most common side effects are abdominal discomfort, diarrhea, nausea, and vomiting.

Anaphylaxis (a serious allergic reaction) is rare but has been reported. Saw palmetto's side effects are also mild and reversible — typically abdominal pain, constipation, diarrhea, dizziness, fatigue, headache, nausea, or vomiting.

Rarely, saw palmetto has been linked to changes in heart rhythm and blood pressure. For pregnancy, saw palmetto safety data advises against use — the rating is likely unsafe because of possible effects on hormones.

For breastfeeding, saw palmetto should also be avoided due to insufficient safety information. Pumpkin seed oil has no data on file for pregnancy or breastfeeding safety; there isn't enough information to know either way, so talk with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Pumpkin Saw Palmetto

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Pumpkin, Saw Palmetto.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; lithium.
  • For scale: 175 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist if you take blood thinners or antiplatelet drugs like warfarin or aspirin — saw palmetto may increase bleeding risk (Moderate). Also flag lithium (pumpkin seed oil may raise your levels), estrogens, or birth control pills (saw palmetto may reduce their effectiveness).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you have an enlarged prostate and no blood thinners, lithium, estrogens, or birth control in your regimen, this product is worth discussing with your pharmacist. Anyone taking blood thinners, lithium, or hormonal medications should check with us before starting.

Pregnant women and those breastfeeding should skip saw palmetto.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Prost-8-Palmetto, straight from the product label.

Brand Montiff
Barcode (UPC) 683268103661
Net contents 90 Soft Gel(s)
Market status On market
Date entered into DSLD Feb 25, 2015
DSLD ID 42077
Product type Botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult Male (18-50 Years), Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Prost-8-Palmetto by Montiff, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Soft Gel(s)
Maximum serving Sizes:
4 Soft Gel(s)
UPC/BARCODE
683268103661
IngredientAmount% DV
Total Carbohydrates65.2 mg--
Protein89.8 mg--
Saturated Fat93.7 mg--
Total Fat320 mg--
Calories from Saturated Fat0 {Calories}--
Pumpkin seed Oil160 mg--
{Soft-gel}491.1 mg--
Saw Palmetto extract160 mg--

Other ingredients: Gelatin, Glycerin, Water, Carob extract concentrate, Titanium Dioxide liquid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 1 to 4 Soft-gels daily, or as recommended by a health care professional. To be used as a Dietary supplement in a normal food program.

General Statements

Best if taken with 1 Montiff Super Antioxidant formula.

MONTIFF

Highest Quality Available

Formulation

Contains no Starch, Corn, Milk, Wheat, Yeast, Sugar, Eggs, Salt, Artificial Colors, Binders, Flavors, Preservatives or fish derivatives.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

Product#10366

Formula

(Saw Palmetto Formula for Prostate Health)

Brand IP Statement(s)

(C)1999 MONTIFF,INC. ALL RIGHTS RESERVED.

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Prost-8-Palmetto by Montiff label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Prost-8-Palmetto label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Prost-8-Palmetto by Montiff

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Soft Gel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Protein

89.8 mg per serving

Pumpkin seed Oil

Interacts with
1 drug
160 mg per serving

Pumpkin is a nutritious squash, and its seeds and seed oil are the parts most often used as supplements, mainly for urinary and prostate symptoms. The...

Pumpkin seed Oil monograph & interactions

{Soft-gel}

491.1 mg per serving
  • › Calories from Saturated Fat

Saw Palmetto extract

Interacts with
174 drugs
160 mg per serving Form: Fatty Acids

Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no bett...

Saw Palmetto extract monograph & interactions

Other (inactive) ingredients: Gelatin, Glycerin, Water, Carob extract concentrate, Titanium Dioxide liquid. These complete the product’s ingredient list but are not active constituents.

Interaction report

Prost-8-Palmetto by Montiff Drug Interactions

Want to check YOUR meds against Prost-8-Palmetto?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
175Drugs
175 Moderate

Ingredients driving the most interactions

Saw Palmetto extract 174
Pumpkin seed Oil 1

Individual Drug Interactions

The ingredients in Prost-8-Palmetto interact with 175 drugs. Click any drug to see the details.

2 of the 4 ingredients in Prost-8-Palmetto interact with drugs. Each result below shows which ingredient is responsible. Saw Palmetto extract Pumpkin seed Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Prost-8-Palmetto with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Saw Palmetto extract3 drug types · 174 drugs

Anticoagulant/Antiplatelet Drugs

Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Saw palmetto is reported to prolong bleeding time. Theoretically, it might increase the risk of bleeding when used concomitantly with anticoagulant or antiplatelet drugs.

Likelihood Possible Evidence D
Contraceptive Drugs

Saw palmetto might reduce the effectiveness of contraceptive drugs.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with contraceptive drugs taken concomitantly.

Likelihood Possible Evidence B
Estrogens

Saw palmetto might reduce the effectiveness of estrogens.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with estrogens taken concomitantly.

Likelihood Possible Evidence B
Saw Palmetto extract full monograph & interactions

Pumpkin seed Oil1 drug type · 1 drug

Lithium

Pumpkin might reduce excretion and increase levels of lithium.
Pumpkin is thought to have diuretic properties. Theoretically, this might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Pumpkin seed Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Prost-8-Palmetto, from the product label.

Montiff

See all Montiff products
Name
Montiff, Inc.
City
Los Angeles
State
CA
ZipCode
90025
Pharmacist Counseling Corner

Prost-8-Palmetto by Montiff: Common Questions

Does Prost-8-Palmetto by Montiff interact with any medications?
Yes. Based on its ingredients, Prost-8-Palmetto has a known interaction with 175 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Prost-8-Palmetto contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is pumpkin seed oil supposed to do in this product?
Pumpkin seed oil is in here for benign prostatic hyperplasia — that's an enlarged prostate. The evidence suggests it's possibly effective for that condition. It's also generally well tolerated by adults.
I've heard saw palmetto is great for prostate health. Does this product really work?
The data we have actually rates saw palmetto as possibly ineffective for benign prostatic hyperplasia specifically. That said, it is possibly effective for one particular prostate procedure called TURP. For other prostate or urinary issues, we don't have enough reliable evidence to say either way.
What side effects might I experience?
The most common ones are mild and reversible — abdominal discomfort, diarrhea, nausea, constipation, dizziness, fatigue, headache, or vomiting. Serious side effects like anaphylaxis or heart rhythm changes are rare. Stop and contact your doctor if you notice anything concerning.
Is it safe to take while breastfeeding?
Saw palmetto should be avoided while breastfeeding because safety data is insufficient. For pumpkin seed oil, we don't have safety data on file for breastfeeding, so there isn't enough information either way. Talk with your doctor or pharmacist before taking this product.
Can I take this if I'm on birth control?
Not without checking with your pharmacist first. Saw palmetto in this product may have antiestrogenic effects that could reduce how well your birth control works. You'll need to discuss whether it's safe for your specific situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Prost-8-Palmetto label
Go deeper

The Full Monographs Behind Prost-8-Palmetto’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Pumpkin

Interacts with 1 drug

Pumpkin is a nutritious squash, and its seeds and seed oil are the parts most often used as supplements, mainly for urinary and prostate symptoms. The evidence for these uses is limited and...

Read the full Pumpkin monograph → Herb & supplement monograph

Saw Palmetto

Interacts with 174 drugs

Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no better than a placebo for most men, though i...

Read the full Saw Palmetto monograph →
Sources

Sources & How We Checked

Prost-8-Palmetto's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 27 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pumpkin 5 references
  1. Marks L, Partin AW, Epstein JI, et al. Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. J Urol 2000;163:1451-6. DOI
  2. Cho YH, Lee SY, Jeong DW, et al. Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. Evid Based Complement Alternat Med 2014;2014:549721. PubMed
  3. Vahlensieck W, Theurer C, Pfitzer E, Patz B, Banik N, Engelmann U. Effects of pumpkin seed in men with lower urinary tract symptoms due to benign prostatic hyperplasia in the one-year, randomized, placebo-controlled GRANU study. Urol Int 2015;94(3):286-95 PubMed
  4. Assouly P. Hair loss associated with cucurbit poisoning. JAMA Dermatol. 2018 May 1;154(5):617-618. PubMed
  5. Gawryjolek J, Ludwig H, Zbikowska-Götz M, Bartuzi Z, Krogulska A. Anaphylaxis after consumption of pumpkin seeds in a 2-y-old child tolerant to its pulp: A case study. Nutrition 2021;89:111272. PubMed

See these in context on the Pumpkin monograph →

Saw Palmetto 22 references
  1. Wilt TJ, Ishani A, Stark G, et al. Saw palmetto extracts for treatment of benign prostatic hyperplasia: a systematic review. JAMA 1998;280:1604-9. PubMed
  2. Carraro JC, Raynaud JP, Koch G, et al. Comparison of phytotherapy (Permixon) with finasteride in the treatment of benign prostate hyperplasia: a randomized international study of 1,098 patients. Prostate 1996;29:231-40. DOI
  3. Di Silverio F, D'Eramo G, Lubrano C, et al. Evidence that Serenoa repens extract displays an antiestrogenic activity in prostatic tissue of benign prostatic hypertrophy patients. Eur Urol 1992;21:309-14. PubMed
  4. Stepanov VN, Siniakova LA, Sarrazin B, Raynaud JP. Efficacy and tolerability of the lipidosterolic extract of Serenoa repens (Permixon) in benign prostatic hyperplasia: a double-blind comparison of two dosage regimens. Adv Ther 1999;16:231-41.
  5. Cheema P, El-Mefty O, Jazieh AR. Intraoperative haemorrhage associated with the use of extract of Saw Palmetto herb: a case report and review of literature. J Intern Med 2001;250:167-9. PubMed
  6. Jibrin I, Erinle A, Saidi A, Aliyu ZY. Saw palmetto-induced pancreatitis. South Med J 2006;99:611-2. PubMed
  7. Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med 2002
  8. Avins AL, Bent S, Staccone S, et al. A detailed safety assessment of a saw palmetto extract. Complement Ther Med 2008;16:147-54. PubMed
  9. Morgia, G., Mucciardi, G., Gali, A., Madonia, M., Marchese, F., Di, Benedetto A., Romano, G., Bonvissuto, G., Castelli, T., Macchione, L., and Magno, C. Treatment of chronic prostatitis/chronic pelvic pain syndrome category IIIA with Serenoa repens plus
  10. Aliaev, IuG, Vinarov, A. Z., Lokshin, K. L., and Spivak, L. G. [Efficiency and safety of prostamol-Uno in patients with chronic abacterial prostatitis]. Urologiia. 2006;(1):47-50.
  11. Agbabiaka, T. B., Pittler, M. H., Wider, B., and Ernst, E. Serenoa repens (saw palmetto): a systematic review of adverse events. Drug Saf 2009;32(8):637-647. PubMed
  12. Wargo, K. A., Allman, E., and Ibrahim, F. A possible case of saw palmetto-induced pancreatitis. South.Med.J. 2010;103(7):683-685. PubMed
  13. Lapi, F., Gallo, E., Giocaliere, E., Vietri, M., Baronti, R., Pieraccini, G., Tafi, A., Menniti-Ippolito, F., Mugelli, A., Firenzuoli, F., and Vannacci, A. Acute liver damage due to Serenoa repens: a case report. Br.J.Clin.Pharmacol. 2010;69(5):558-560.
  14. Mantovani, F. Serenoa repens in benign prostatic hypertrophy: analysis of 2 Italian studies. Minerva Urol.Nefrol. 2010;62(4):335-340.
  15. Hanaka, M., Yoshii, C., Yatera, K., Ito, C., Chojin, Y., Nagata, S., Yamasaki, K., Nishida, C., Kawanami, T., Kawanami, Y., Ishimoto, H., and Mukae, H. [A case of rhabdomyolysis caused by saw palmetto of healthy foods]. J.UOEH. 6-1-2012;34(2):193-199. PubMed
  16. Miroddi, M., Carni, A., Mannucci, C., Moleti, M., Navarra, M., and Calapai, G. Hot flashes in a young girl: a wake-up call concerning Serenoa repens use in children. Pediatrics 2012;130(5):e1374-e1376.
  17. Braeckman J. The extract of Serenoa repens in the treatment of benign prostatic hyperplasia: a multicenter open study. Current Therapeutic Research 1994;55(7):776-785. DOI
  18. Jipescu D, Patel A, Bohra H, Pientka A. Rare case of saw palmetto induced heart block. JACC 2017;69(11) supplement:2310.
  19. Morabito P, Miroddi M, Giovinazzo S, Spina E, Calapai G. Serenoa repens as an endocrine disruptor in a 10-year-Old young girl: a new case report. Pharmacology. 2015;96(1-2):41-3. doi: 10.1159/000431327.
  20. Gammoudi R, Ameur K, Ouni B, et al. Fixed drug eruption to Serenoa repens: first case report and consideration of the use of herbal medicine. Dermatol Ther 2020 Aug 29:e14247.
  21. Paulis G, Paulis A, Perletti G. Serenoa repens and its effects on male sexual function. A systematic review and meta-analysis of clinical trials. Arch Ital Urol Androl 2021;93(4):475-480. PubMed
  22. Venkateswaran S, Declet-Bauzo R, Shodeinde M, Gilford P. Postoperative Retroperitoneal Hematoma: A Case of Saw Palmetto and the Importance of Primary Care Intervention. HCA Healthc J Med 2020;1(5):279-282. PubMed

See these in context on the Saw Palmetto monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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