Major interaction on record — check this product against your medications before combining. Based on 9 of 10 ingredients. Check your meds →
Dietary supplement

Prostatonic Ingredients & Drug Interactions

by Herbs Etc.

Prostatonic label
See full label image
Liquid Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Prostatonic against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Prostatonic is a dietary supplement by Herbs Etc. with 10 active ingredients. Its ingredients are commonly taken for low libido / aphrodisiac, anxiety and stress, mood and mild low energy.Based on those ingredients, 687 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Yerba Mansa Root Extract, American Ginseng Root Extract, Saw Palmetto Berry Extract, Fresh. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Prostatonic by Herbs Etc.

Ask about any prescription or over-the-counter medication and we check it for interactions with Prostatonic by Herbs Etc. — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Prostatonic by Herbs Etc.

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 10 active ingredients.
  • “Proprietary Extract Blend” is a proprietary blend — the label gives one combined amount (0.75 mL) without saying how much of each component you get.

Prostatonic is a liquid formula with 10 active ingredients: damiana leaf extract, yarrow flower top extract, American ginseng root extract, pipsissewa herb extract, yerba mansa root extract, saw palmetto berry extract, dong quai cured root extract, stinging nettle root extract, cleavers herb extract, and sarsaparilla root extract. The product also contains alcohol, purified water, and glycerine as inactive ingredients.

These herbs have been traditionally used to support prostate and urinary health. American ginseng is included for immune support, while saw palmetto is a well-known botanical for prostate wellness.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: Promotes healthy prostate function.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS), Prostatitis, Prostate health, Lower urinary tract symptoms, Urinary flow.
  • The closest evidence on file: Saw Palmetto is rated "Possibly Ineffective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).
  • Also on file: Stinging Nettle is rated "Insufficient Reliable Evidence To Rate" for Benign prostatic hyperplasia (BPH).
  • Also on file: Saw Palmetto is rated "Insufficient Reliable Evidence To Rate" for Chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS), Prostatitis, Non-neurogenic lower urinary tract symptoms (LUTS).

Evidence for these ingredients is limited or mixed. American ginseng appears possibly effective for upper respiratory infections, but the other ingredients lack established effectiveness for the conditions we have data on.

Saw palmetto shows possibly ineffective evidence for benign prostate enlargement when measured against certain standards, though it appears possibly effective for symptoms after transurethral resection of the prostate. Stinging nettle is possibly effective for diabetes.

For most of the uses these herbs are traditionally taken for—including prostate support—the evidence is simply not established in our data.

The evidence, ingredient by ingredient Damiana Yarrow American Ginseng Pipsissewa Yerba Mansa Saw Palmetto Dong Quai Stinging Nettle

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 8 of the 9 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 9 of 9.
  • General safety write-ups exist for 9 of 9.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most of these ingredients are generally well tolerated when used short-term, though safety data are limited for several of them. Damiana at very high doses (200 grams of extract) has caused severe reactions resembling poisoning.

Stinging nettle is likely unsafe in pregnancy and may harm the uterus; yarrow is also traditionally avoided in pregnancy for the same reason. Saw palmetto is likely unsafe during pregnancy due to hormone effects.

American ginseng and dong quai are possibly unsafe in pregnancy. Pipsissewa and several others lack enough safety data in pregnancy—avoid or talk with your doctor.

For breastfeeding, safety information is insufficient or absent for most ingredients; the safer choice is to avoid use. Saw palmetto is likely unsafe while nursing.

Yarrow, stinging nettle, and American ginseng all lack reliable safety data for breastfeeding.

Side effects, ingredient by ingredient Damiana Yarrow American Ginseng Pipsissewa Yerba Mansa Saw Palmetto Dong Quai Stinging Nettle

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 8 of the 9 matched ingredients can interact with medications — Yarrow, Yerba Mansa, Sarsaparilla, Stinging Nettle, Damiana, among others.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; heart-rhythm medications; lithium.
  • For scale: 687 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Prostatonic, double-check with your pharmacist if you take warfarin or other blood thinners (Major risk with American ginseng and dong quai), antidiabetes drugs, lithium, estrogens or birth control pills, blood pressure medications, heart medications like digoxin, MAOIs, immunosuppressants, diuretics, or central nervous system depressants. No interactions are documented for cleavers herb extract, but we hold no data for it.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with graded evidence leaning against its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Prostatonic is a traditional herbal blend for prostate and urinary health, but it contains multiple ingredients that interact with common medications—especially blood thinners, diabetes drugs, lithium, and birth control. If you take any prescription medication, check it against our interaction tool before starting.

Pregnant or breastfeeding? Talk with your pharmacist or doctor first; safety data are limited for most of these herbs in those settings.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 9 of 10 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Prostatonic, straight from the product label.

Brand Herbs Etc.
Barcode (UPC) 765704130018
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Nov 22, 2024
DSLD ID 320880
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Prostatonic by Herbs Etc., sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
30 Drop(s)
Maximum serving Sizes:
30 Drop(s)
Servings per container
40
UPC/BARCODE
765704130018
IngredientAmount% DV
Proprietary Extract Blend0.75 mL--
Damiana leaf extract0 NP--
Yarrow Flower Top Extract, Fresh0 NP--
American Ginseng Root Extract0 NP--
Pipsissewa Herb Extract0 NP--
Yerba Mansa Root Extract0 NP--
Saw Palmetto Berry Extract, Fresh0 NP--
Dong Quai Cured Root Extract0 NP--
Stinging Nettle Root Extract, Fresh0 NP--
Cleavers Herb Extract, Fresh0 NP--
Sarsparilla root extract0 NP--

Other ingredients: Alcohol, Water, Purified, Glycerine

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Promotes a healthy prostate function

Gluten free No artificial preservatives.

Vegan

Manufactured in Santa Fe, NM.

FDA Statement of Identity

Herbal Supplement

Formula

Prostatonic is made with healthy prostate function promoting herbs, including Saw Palmetto, Stinging Nettle, and Damiana.

General Statements

We apply our company philosophy to Prostatonic, as we do to all of our herbal medicines. That philosophy is to do what's right, which extends to choosing the right herbs, using the right processes, and making the right formulations that support your health needs. We do all of this to bring you herbal medicines made right.

Herbal medicine

Suggested/Recommended/Usage/Directions

Suggested use: Take 30 drops in water twice a day for an unlimited period of time.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Prostatonic by Herbs Etc. label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Prostatonic label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Prostatonic by Herbs Etc.

These are the 10 active ingredients this product is made of. Select any to open its full monograph.

Serving size30 Drop(s) Dosage formLiquid Servings per container40 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Other (inactive) ingredients: Alcohol, Water, Purified, Glycerine. These complete the product’s ingredient list but are not active constituents.

Interaction report

Prostatonic by Herbs Etc. Drug Interactions

Want to check YOUR meds against Prostatonic?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
687Drugs
2 Major 685 Moderate

Ingredients driving the most interactions

Yerba Mansa Root Extract 248
American Ginseng Root Extract 217
Saw Palmetto Berry Extract, Fresh 174
Stinging Nettle Root Extract, Fresh 164
Dong Quai Cured Root Extract 163

Individual Drug Interactions

The ingredients in Prostatonic interact with 687 drugs. Click any drug to see the details.

8 of the 10 ingredients in Prostatonic interact with drugs. Each result below shows which ingredient is responsible. Yerba Mansa Root Extract American Ginseng Root Extract Saw Palmetto Berry Extract, Fresh Stinging Nettle Root Extract, Fresh Dong Quai Cured Root Extract Damiana leaf extract Sarsparilla root extract Yarrow Flower Top Extract, Fresh

Each ingredient & the kinds of drugs it affects

For each ingredient in Prostatonic with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Yerba Mansa Root Extract1 drug type · 248 drugs

Cns Depressants

Theoretically, concomitant use might cause additive or prolonged sedative effects.

Likelihood Probable Evidence D
Yerba Mansa Root Extract full monograph & interactions

American Ginseng Root Extract4 drug types · 217 drugs

Warfarin (Coumadin)

American ginseng seems to decrease the effectiveness of warfarin therapy.
Healthy patients receiving warfarin 5 mg daily, who also take American ginseng 1 gram twice daily, seem to have a significantly reduced international normalized ratio (INR).

Likelihood Likely Evidence B
Antidiabetes Drugs

Theoretically, taking American ginseng with antidiabetes drugs might increase the risk of hypoglycemia.
American ginseng seems to lower postprandial blood glucose. Theoretically, concomitant use with antidiabetes drugs might enhance blood glucose lowering effects and possibly cause hypoglycemia.

Likelihood Probable Evidence B
Immunosuppressants

Theoretically, American ginseng use might interfere with immunosuppressive therapy.
American ginseng seems to stimulate immune function. Theoretically, American ginseng might decrease the effectiveness of immunosuppressant drugs.

Likelihood Possible Evidence D
Monoamine Oxidase Inhibitors (Maois)

Theoretically, American ginseng can interfere with MAOI therapy.
There is one case report of insomnia, headache, and tremors when an unspecified ginseng product was used with phenelzine (Nardil), an MAOI. There is also one case report of hypomania when an unspecified ginseng product was used with phenelzine. Theoretically, American ginseng may interfere with MAOI therapy.

Likelihood Possible Evidence D
American Ginseng Root Extract full monograph & interactions

Saw Palmetto Berry Extract, Fresh3 drug types · 174 drugs

Anticoagulant/Antiplatelet Drugs

Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Saw palmetto is reported to prolong bleeding time. Theoretically, it might increase the risk of bleeding when used concomitantly with anticoagulant or antiplatelet drugs.

Likelihood Possible Evidence D
Contraceptive Drugs

Saw palmetto might reduce the effectiveness of contraceptive drugs.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with contraceptive drugs taken concomitantly.

Likelihood Possible Evidence B
Estrogens

Saw palmetto might reduce the effectiveness of estrogens.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with estrogens taken concomitantly.

Likelihood Possible Evidence B
Saw Palmetto Berry Extract, Fresh full monograph & interactions

Stinging Nettle Root Extract, Fresh4 drug types · 164 drugs

Antidiabetes Drugs

Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Clinical research shows that stinging nettle might decrease blood glucose levels in patients with diabetes.

Likelihood Possible Evidence B
Diuretic Drugs

Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Animal research suggests that the above ground parts and roots of stinging nettle may have a diuretic effect.

Likelihood Possible Evidence D
Lithium

Theoretically, stinging nettle might reduce excretion and increase levels of lithium.
Animal research suggests that stinging nettle has diuretic and natriuretic properties, which could alter the excretion of lithium. The dose of lithium might need to be decreased.

Likelihood Possible Evidence D
Warfarin (Coumadin)

There is some concern that stinging nettle might decrease the effects of anticoagulant drugs such as warfarin.
Stinging nettle contains a significant amount of vitamin K. When taken in large quantities, this might interfere with the activity of warfarin.

Likelihood Possible Evidence D
Stinging Nettle Root Extract, Fresh full monograph & interactions

Dong Quai Cured Root Extract3 drug types · 163 drugs

Warfarin (Coumadin)

Dong quai may increase the risk of bleeding when used with warfarin.
Case reports suggest that concomitant use of dong quai with warfarin can increase the anticoagulant effects of warfarin and increase the risk of bleeding. In one case, after 4 weeks of taking dong quai 565 mg once or twice daily, the international normalized ratio (INR) increased to 4.9. The INR normalized 4 weeks after discontinuation of dong quai.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, dong quai may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Animal studies suggest that dong quai has antithrombin activity and inhibits platelet aggregation due to its coumarin components. Additionally, some case reports in humans suggest that dong quai can increase the anticoagulant effects of warfarin. However, clinical research in healthy adults shows that taking 1 gram of dong quai root daily for 3 weeks does not significantly inhibit platelet aggregation or cause bleeding. Until more is known, use dong quai with caution in patients taking antiplatelet/anticoagulant drugs.

Likelihood Possible Evidence D
Estrogens

Theoretically, dong quai may reduce the effects of estrogens.
Dong quai has estrogenic effects. Theoretically, concomitant use of large amounts of dong quai might interfere with hormone replacement therapy due to competition for estrogen receptors.

Likelihood Possible Evidence D
Dong Quai Cured Root Extract full monograph & interactions

Damiana leaf extract1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that taking damiana lowers blood glucose level.

Likelihood Possible Evidence D
Damiana leaf extract full monograph & interactions

Sarsparilla root extract2 drug types · 2 drugs

Digoxin (Lanoxin)

Theoretically, concomitant use of sarsaparilla with digoxin might increase the risk of cardiac toxicity.
Sarsaparilla is thought to have diuretic properties, which could potentially cause potassium loss. Overuse or misuse of sarsaparilla with cardiac glycoside therapy might increase the risk of cardiac toxicity due to potassium loss.

Likelihood Possible Evidence D
Lithium

Theoretically, sarsaparilla might increase the effects and adverse effects of lithium.
Sarsaparilla is thought to have diuretic properties. Due to these effects, sarsaparilla might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Sarsparilla root extract full monograph & interactions

Yarrow Flower Top Extract, Fresh1 drug type · 1 drug

Lithium

Theoretically, taking yarrow with lithium might increase the levels and adverse effects of lithium.
Animal research shows that yarrow has diuretic activity. Theoretically, due to these potential diuretic effects, yarrow might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Yarrow Flower Top Extract, Fresh full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Prostatonic, from the product label.

Herbs Etc.

Name
Herbs, Etc., Inc.
Street Address
1340 Rufina Circle
City
Santa Fe
State
NM
ZipCode
87507
Web Address
www.herbsetc.com
Pharmacist Counseling Corner

Prostatonic by Herbs Etc.: Common Questions

Does Prostatonic by Herbs Etc. interact with any medications?
Yes. Based on its ingredients, Prostatonic has a known interaction with 687 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Prostatonic contains 10 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does Prostatonic actually work for prostate health?
The evidence varies by ingredient and is often limited. Saw palmetto shows possibly ineffective evidence for benign prostate enlargement in some studies, though it's possibly effective for certain post-surgical symptoms. For most of these herbs and the prostate support they're traditionally used for, the evidence just isn't established in our data. Talk with your doctor about whether Prostatonic fits your specific situation.
Can I take this if I'm on warfarin?
No—not without checking with your doctor first. American ginseng and dong quai in this product can reduce warfarin's effectiveness or increase bleeding risk. Your doctor may need to adjust your dose or monitor you more closely. Absolutely bring this product to your pharmacist before starting.
What about side effects?
Most ingredients are generally well tolerated, but some can cause mild effects: saw palmetto may cause abdominal pain, diarrhea, headache, or dizziness. Damiana at high doses has caused severe reactions. Stinging nettle can cause constipation or diarrhea. Yarrow can trigger allergic skin reactions in some people, especially with sun exposure. If you notice anything unusual, stop and talk to your pharmacist.
Is it safe to take while pregnant?
No. Several ingredients—stinging nettle, yarrow, and saw palmetto—are likely unsafe or possibly unsafe during pregnancy. Others lack enough safety data. If you're pregnant or planning to become pregnant, talk with your doctor or pharmacist before use.
Can I take this while breastfeeding?
It's best to avoid it. Safety data during breastfeeding are insufficient or absent for most ingredients in this product, and saw palmetto is likely unsafe while nursing. Talk with your doctor or pharmacist about whether it's right for you.
Does this interact with diabetes medications?
Yes—potentially. American ginseng, damiana, and stinging nettle may all lower blood sugar, so combined with diabetes drugs they could increase the risk of low blood sugar. If you take diabetes medication, check with your pharmacist before starting, and monitor your blood sugar closely.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Prostatonic label
Go deeper

The Full Monographs Behind Prostatonic’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Damiana

Interacts with 86 drugs

Damiana is a traditional herb most famous as an aphrodisiac and mild mood-lifter, but solid human evidence for any of its uses is very limited. It is generally well tolerated in the small am...

Read the full Damiana monograph → Herb & supplement monograph

Yarrow

Interacts with 1 drug

Yarrow is a traditional herb long used for wounds, digestive complaints, and colds, but high-quality human studies are very limited, so its benefits are not well proven. It is generally used...

Read the full Yarrow monograph → Herb & supplement monograph

American Ginseng

Interacts with 217 drugs

American ginseng is an herbal root used as an 'adaptogen' to support energy, stress, immune function, and blood sugar. Some uses—such as reducing the chance or length of colds and modestly l...

Read the full American Ginseng monograph → Herb & supplement monograph

Pipsissewa

Pipsissewa is a North American forest herb with a long history of traditional use as a diuretic and urinary remedy, but modern human research is very limited. There is not enough good eviden...

Read the full Pipsissewa monograph → Herb & supplement monograph

Yerba Mansa

Interacts with 248 drugs

Yerba mansa is a traditional Southwestern and Mexican medicinal plant used for sore throats, skin problems, and infections. Modern scientific evidence in humans is very limited, so its effec...

Read the full Yerba Mansa monograph → Herb & supplement monograph

Saw Palmetto

Interacts with 174 drugs

Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no better than a placebo for most men, though i...

Read the full Saw Palmetto monograph → Herb & supplement monograph

Dong Quai

Interacts with 163 drugs

Dong Quai is a traditional Chinese herb often called "female ginseng" and is mostly used for menstrual and menopausal complaints. High-quality scientific evidence that it works for these use...

Read the full Dong Quai monograph → Herb & supplement monograph

Stinging Nettle

Interacts with 164 drugs

Stinging nettle is a common plant used as food and in traditional medicine, most often for prostate symptoms, allergies, and joint pain. The evidence is mixed and mostly preliminary, so it i...

Read the full Stinging Nettle monograph → Herb & supplement monograph

Sarsaparilla

Interacts with 2 drugs

Sarsaparilla is a traditional root used in teas, tonics, and old-fashioned root beer flavoring. Modern evidence for its health claims is very limited and comes mostly from lab studies, so it...

Read the full Sarsaparilla monograph →
Sources

Sources & How We Checked

Prostatonic's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 91 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Damiana 2 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Alarcon-Aquilar FJ, Roman-Ramos R, Perez-Gutierrez S, et al. Study of the anti-hyperglycemic effect of plants used as antidiabetics. J Ethnopharmacol 1998;61:101-10. PubMed

See these in context on the Damiana monograph →

Yarrow 8 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Uter, W., Nohle, M., Randerath, B., and Schwanitz, H. J. Occupational contact urticaria and late-phase bronchial asthma caused by compositae pollen in a florist. Am J Contact Dermat. 2001;12(3):182-184. DOI
  3. Schempp, C. M., Schopf, E., and Simon, J. C. [Plant-induced toxic and allergic dermatitis (phytodermatitis)]. Hautarzt 2002;53(2):93-97.
  4. Jovanovic, M., Poljacki, M., Duran, V., Vujanovic, L., Sente, R., and Stojanovic, S. Contact allergy to Compositae plants in patients with atopic dermatitis. Med Pregl. 2004;57(5-6):209-218. PubMed
  5. Becker LC, Bergfeld WF, Belsito DV, et al. Safety assessment of Achillea millefolium as used in cosmetics. Int J Toxicol. 2016;35(3 suppl):5S-15S.
  6. Zakeri S, Esmaeilzadeh S, Gorji N, Memariani Z, Moeini R, Bijani A. The effect of Achillea millefolium L. on vulvovaginal candidiasis compared with clotrimazole: A randomized controlled trial. Complement Ther Med. 2020;52:102483. PubMed
  7. de Souza P, Crestani S, da Silva Rde C, et al. Involvement of bradykinin and prostaglandins in the diuretic effects of Achillea millefolium L. (Asteraceae). J Ethnopharmacol. 2013 Aug 26;149(1):157-61. PubMed
  8. Miranzadeh S, Adib-Hajbaghery M, Soleymanpoor L, Ehsani M. Effect of adding the herb Achillea millefolium on mouthwash on chemotherapy induced oral mucositis in cancer patients: A double-blind randomized controlled trial. Eur J Oncol Nurs. 2015;19(3):207- PubMed

See these in context on the Yarrow monograph →

American Ginseng 12 references
  1. Shader RI, Greenblatt DJ. Phenelzine and the dream machine-ramblings and reflections. J Clin Psychopharmacol 1985;5:65. PubMed
  2. Jones BD, Runikis AM. Interaction of ginseng with phenelzine. J Clin Psychopharmacol 1987;7:201-2. PubMed
  3. Janetzky K, Morreale AP. Probable interaction between warfarin and ginseng. Am J Health Syst Pharm 1997;54:692-3. PubMed
  4. Vuksan V, Sievenpiper JL, Koo VY, et al. American ginseng (Panax quinquefolius L) reduces postprandial glycemia in nondiabetic subjects and subjects with type 2 diabetes mellitus. Arch Intern Med 2000;160:1009-13. PubMed
  5. Vuksan V, Stavro MP, Sievenpiper JL, et al. Similar postprandial glycemic reductions with escalation of dose and administration time of American ginseng in type 2 diabetes. Diabetes Care 2000;23:1221-6. PubMed
  6. Chan LY, Chiu PY, Lau TK. An in-vitro study of ginsenoside Rb(1)-induced teratogenicity using a whole rat embryo culture model. Hum Reprod 2003;18:2166-8..
  7. McElhaney JE, Gravenstein S, Cole SK, et al. A Placebo-Controlled Trial of a Proprietary Extract of North American Ginseng (CVT-E002) to Prevent Acute Respiratory Illness in Institutionalized Older Adults. J Am Geriatr Soc 2004;52:13-9. PubMed
  8. Yuan CS, Wei G, Dey L, et al. American ginseng reduces warfarin's effect in healthy patients: a randomized, controlled trial. Ann Intern Med 2004;141:23-7.
  9. Predy GN, Goel V, Lovlin R, et al. Efficacy of an extract of North American ginseng containing poly-furanosyl-pyranosyl-saccharides for preventing upper respiratory tract infections: a randomized controlled trial. CMAJ 2005;173:1043-8.. PubMed
  10. McElhaney JE, Goel V, Toane B, et al. Efficacy of COLD-fX in the prevention of respiratory symptoms in community-dwelling adults: a randomized, double-blinded, placebo controlled trial. J Altern Complement Med 2006;12:153-7. PubMed
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Pipsissewa 1 reference
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See these in context on the Pipsissewa monograph →

Yerba Mansa 1 reference
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See these in context on the Yerba Mansa monograph →

Saw Palmetto 22 references
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Dong Quai 19 references
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Stinging Nettle 23 references
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Sarsaparilla 3 references
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See these in context on the Sarsaparilla monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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