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Dietary supplement

Pure Inositol 650 mg Ingredients & Drug Interactions

by Freeda

Pure Inositol 650 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pure Inositol 650 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Pure Inositol 650 mg is a dietary supplement by Freeda with 1 active ingredient. Its ingredients are commonly taken for polycystic ovary syndrome (pcos), anxiety and panic, depression and mood.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Inositol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Pure Inositol 650 mg by Freeda

Ask about any prescription or over-the-counter medication and we check it for interactions with Pure Inositol 650 mg by Freeda — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Pure Inositol 650 mg by Freeda

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Pure Inositol contains one active ingredient: inositol at 650 mg per capsule. Inositol is a naturally occurring carbohydrate compound that plays a role in cell signaling and metabolism.

The capsule itself is made from vegetable cellulose, and the product also contains cellulose, vegetarian stearate, and silica as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Inositol's overall clinical evidence instead.

Moderate

Some clinical evidence supports Inositol for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Polycystic ovary syndrome (PCOS) — rated "Possibly Effective" (Natural Medicines).
  • On file: Preterm labor — rated "Possibly Effective" (Natural Medicines).
  • On file: Metabolic syndrome — rated "Possibly Effective" (Natural Medicines).

Research suggests inositol is possibly effective for polycystic ovary syndrome (PCOS), metabolic syndrome, and preterm labor. For anxiety, diabetic nerve pain (neuropathy), and depression, the evidence we have rates it possibly ineffective — meaning studies haven't shown it works for these uses.

If you're considering inositol for a specific condition, it's worth talking it over with your doctor to see if the evidence fits your situation.

The evidence, ingredient by ingredient Inositol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Inositol is generally well tolerated at typical doses. The most common side effects when taken by mouth are diarrhea, gas, and nausea — usually mild and digestive in nature.

There's also a report of cold and allergy symptoms in children when inositol was combined with omega-3 fatty acids in research. For pregnancy, safety data is limited — inositol has sometimes been studied in pregnant people, but use only under medical supervision since we don't fully know it's safe.

For breastfeeding, data isn't on file. Talk with your doctor before using inositol if you're pregnant, planning to be, or breastfeeding.

Side effects, ingredient by ingredient Inositol

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Inositol.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs — insulin, metformin, sulfonylureas, or any other diabetes medication — double-check your specific medications before starting inositol. The risk is moderate: inositol can lower blood sugar and may increase the chance of low blood sugar when combined with diabetes meds.

Your doctor or pharmacist can tell you whether it's safe for you and if your diabetes medication dose needs watching.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Pure Inositol may be worth considering if you have PCOS, metabolic syndrome, or preterm labor concerns — the evidence suggests it could help. If you take diabetes medication, you'll need to check with your doctor or pharmacist first, since inositol lowers blood sugar.

Pregnant or breastfeeding? Talk it over with your healthcare provider, since safety data is limited.

Start with a conversation with your own doctor or pharmacist before adding this to your routine.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pure Inositol 650 mg, straight from the product label.

Brand Freeda
Barcode (UPC) 758487002320
Net contents 250 Veg Cap(s)
Market status On market
Date entered into DSLD May 22, 2020
DSLD ID 221325
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pure Inositol 650 mg by Freeda, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
1 Vegetarian Capsule(s)
UPC/BARCODE
758487002320
IngredientAmount% DV
Inositol650 mg--

Other ingredients: Vegetable Cellulose Capsule, Cellulose, Vegetarian Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

No gluten No lactose No artificial colors No artificial flavors No animal derivatives No sugar or starch No gelatin No yeast

Vegan

Seals/Symbols

Manufactured in a GMP certified facility in the USA

NSKC (New Square Rabbinical Kashrus Council) OU Pareve (Kosher)

General Statements

Freeda since 1928

Now in capsules

FDA Statement of Identity

Dietary Supplement

Formula

NSKC (New Square Rabbinical Kashrus Council) OU Pareve (Kosher)

Suggested/Recommended/Usage/Directions

Suggested Use: Adults, take one (1) capsule daily, preferably with food and liquid.

Precautions

Keep out of the reach of children.

Storage

Store product at room temperature. Do not expose to excessive heat or moisture.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pure Inositol 650 mg by Freeda label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pure Inositol 650 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pure Inositol 650 mg by Freeda

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Amounts shown are per serving.

Inositol

Interacts with
86 drugs
650 mg per serving

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...

Inositol monograph & interactions

Other (inactive) ingredients: Vegetable Cellulose Capsule, Cellulose, Vegetarian Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pure Inositol 650 mg by Freeda Drug Interactions

Want to check YOUR meds against Pure Inositol 650 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Inositol 86

Individual Drug Interactions

The ingredients in Pure Inositol 650 mg interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Pure Inositol 650 mg interact with drugs. Each result below shows which ingredient is responsible. Inositol

Each ingredient & the kinds of drugs it affects

For each ingredient in Pure Inositol 650 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Inositol1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that inositol lowers blood glucose levels and glycated hemoglobin (HbA1c) levels in patients with diabetes.

Likelihood Possible Evidence A
Inositol full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pure Inositol 650 mg, from the product label.

Freeda

See all Freeda products
Name
Freeda Health
City
Brooklyn
State
NY
ZipCode
11210
Phone Number
1-800-777-3737
Web Address
www.freedahealth.com
Pharmacist Counseling Corner

Pure Inositol 650 mg by Freeda: Common Questions

Does Pure Inositol 650 mg by Freeda interact with any medications?
Yes. Based on its ingredients, Pure Inositol 650 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pure Inositol 650 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take inositol if I have diabetes?
Inositol does lower blood sugar, so taking it with diabetes medication carries a moderate risk of low blood sugar (hypoglycemia). Talk with your doctor or pharmacist before starting — they can advise whether it's right for you and monitor you closely if you do.
What are the most common side effects?
The most common side effects are digestive: diarrhea, gas, and nausea. These tend to be mild. Inositol is generally well tolerated overall, but if you have a sensitive stomach, start low and see how you do.
Is inositol safe during pregnancy?
Inositol is rated possibly safe in pregnancy and has been studied in pregnant people, but safety isn't fully established. Use only under medical supervision — talk with your doctor before taking it while pregnant or planning to be.
Does inositol actually help with PCOS?
Research rates inositol as possibly effective for PCOS. That means evidence suggests it may help, but more study is needed. It's worth discussing with your doctor to see if it fits your treatment plan.
Will inositol help my depression or anxiety?
For depression and anxiety, research rates inositol as possibly ineffective — studies haven't shown it works for these uses. If you're looking for help with mood, talk with your doctor about other options that have stronger evidence.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pure Inositol 650 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pure Inositol 650 mg label
Go deeper

The Full Monographs Behind Pure Inositol 650 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Inositol

Interacts with 86 drugs

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, mood, and metabolic concerns. The stronge...

Read the full Inositol monograph →
Sources

Sources & How We Checked

Pure Inositol 650 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Inositol 14 references
  1. Palatnik A, Frolov K, Fux M, Benjamin J. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. J Clin Psychopharmacol 2001;21:335-9.. PubMed
  2. Allan SJ, Kavanagh GM, Herd RM, Savin JA. The effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trial. Br J Dermatol 2004;150:966-9. PubMed
  3. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  4. Kamenov Z, Kolarov G, Gateva A, Carlomagno G, Genazzani AD. Ovulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance. Gynecol Endocrinol 2015;31(2):131-5. PubMed
  5. Matarrelli B, Vitacolonna E, D'Angelo M, et al. Effect of dietary myo-inositol supplementation in pregnancy on the incidence of maternal gestational diabetes mellitus and fetal outcomes: a randomized controlled trial. J Matern Fetal Neonatal Med 2013;26(1 PubMed
  6. Mukai T, Kishi T, Matsuda Y, Iwata N. A meta-analysis of inositol for depression and anxiety disorders. Hum Psychopharmacol 2014;29(1):55-63. PubMed
  7. Farren M, Daly N, McKeating A, Kinsley B, Turner MJ, Daly S. The Prevention of Gestational Diabetes Mellitus With Antenatal Oral Inositol Supplementation: A Randomized Controlled Trial. Diabetes Care. 2017;40(6):759-63. PubMed
  8. Zheng X, Liu Z, Zhang Y, et al. Relationship Between Myo-Inositol Supplementary and Gestational Diabetes Mellitus: A Meta-Analysis. Medicine (Baltimore). 2015;94(42):e1604. PubMed
  9. Crawford TJ, Crowther CA, Alsweiler J, Brown J. Antenatal dietary supplementation with myo-inositol in women during pregnancy for preventing gestational diabetes. Cochrane Database Syst Rev. 2015;(12):CD011507. PubMed
  10. Maurizi AR, Menduni M, Del Toro R, et al. A pilot study of D-chiro-inositol plus folic acid in overweight patients with type 1 diabetes. Acta Diabetol. 2017;54(4):361-65. PubMed
  11. Leppink EW, Redden SA, Grant JE. A double-blind, placebo-controlled study of inositol in trichotillomania. Int Clin Psychopharmacol. 2017;32(2):107-14. PubMed
  12. Lam S, Mandrekar SJ, Gesthalter Y. A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia. Cancer Prev Res (Phila). 2016;9(12):906-14.
  13. Wozniak J, Faraone SV, Chan J, et al. A randomized clinical trial of high eicosapentaenoic acid omega-3 fatty acids and inositol as monotherapy and in combination in the treatment of pediatric bipolar spectrum disorders: a pilot study. J Clin Psychiatry. PubMed
  14. Vitale SG, Corrado F, Caruso S, et al. Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-

See these in context on the Inositol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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