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Dietary supplement

Pure Inositol Crystals Ingredients & Drug Interactions

by Source Naturals

Pure Inositol Crystals label
See full label image
Powder Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pure Inositol Crystals against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Pure Inositol Crystals is a dietary supplement by Source Naturals with 1 active ingredient. Its ingredients are commonly taken for polycystic ovary syndrome (pcos), anxiety and panic, depression and mood.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Inositol Crystals. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Pure Inositol Crystals by Source Naturals

Ask about any prescription or over-the-counter medication and we check it for interactions with Pure Inositol Crystals by Source Naturals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Pure Inositol Crystals by Source Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: inositol crystals, a naturally occurring compound your body makes and also gets from foods like grains and citrus. It's a form of vitamin B that plays a role in cell signaling and glucose metabolism.

The product is pure powder with no inactive ingredients listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: healthy cell membranes and cellular function.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

Inositol has possibly effective evidence for polycystic ovary syndrome (PCOS) and metabolic syndrome. It's also possibly effective for preterm labor.

For anxiety, depression, and diabetic nerve damage (diabetic neuropathy), the evidence rates as possibly ineffective—meaning the data we have doesn't support benefit for those uses.

The evidence, ingredient by ingredient Inositol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Inositol is generally well tolerated at common doses. The most common side effects when taken by mouth are diarrhea, gas, and nausea—mild digestive complaints.

In one report, inositol combined with omega-3 fatty acids was linked to cold and allergy symptoms in children, though this isn't common. There's also a single case of a person with bipolar disorder who had manic symptoms after consuming an energy drink containing inositol, caffeine, taurine, and other ingredients over several days—but it's unclear whether inositol alone caused it.

For pregnancy, safety data isn't fully established, so use it only under your doctor's supervision if you're pregnant. For breastfeeding, we don't have enough reliable information on file—talk with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Inositol

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Inositol.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any antidiabetes drug—insulin, metformin, or any other blood sugar medication—check with your doctor or pharmacist before starting this product. Inositol lowers blood glucose, and combining it with your medication could risk low blood sugar.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Inositol may be worth considering if you have PCOS, metabolic syndrome, or are at risk for preterm labor and want to explore it with your provider. If you take antidiabetes medication, this is a product to clear with your doctor first because of the blood sugar interaction.

Pregnant or breastfeeding women should discuss it with their healthcare provider before starting. Check your exact medications using the tool on this page.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 20, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pure Inositol Crystals, straight from the product label.

Brand Source Naturals
Barcode (UPC) 021078004882
Net contents 8 Oz(s); 226.8 Gram(s)
Market status On market
Date entered into DSLD Nov 20, 2017
DSLD ID 80980
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pure Inositol Crystals by Source Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.125 tsp
Maximum serving Sizes:
0.25 tsp
Servings per container
378
UPC/BARCODE
021078004882
IngredientAmount% DV
Inositol Crystals600 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

General Statements

Inositol is an essential component of the phospholipids that make up cellular membranes, and so is found in virtually every cell in the body. Recent research indicates that inositol helps establish healthy cell membranes which facilitate nerve impulses.

Suggested/Recommended/Usage/Directions

Suggested Use: 1/8 to 1/4 teaspoon daily, mixed with water or juice between meals or at bedtime.

Precautions

Note: If you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product.

Do not use if either tamper-evident seal is broken or missing.

Keep out of the reach of children.

Formulation

Suitable for Vegetarians.

Contains no yeast, dairy, egg, gluten, soy or wheat. Contains no starch, salt, preservatives, or artificial color, flavor or fragrance.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

SN0488 REV C172

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pure Inositol Crystals by Source Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pure Inositol Crystals label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pure Inositol Crystals by Source Naturals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.125 tsp Dosage formPowder Servings per container378 Amounts shown are per serving.

Inositol Crystals

Interacts with
86 drugs
600 mg per serving

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...

Inositol Crystals monograph & interactions
Interaction report

Pure Inositol Crystals by Source Naturals Drug Interactions

Want to check YOUR meds against Pure Inositol Crystals?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Inositol Crystals 86

Individual Drug Interactions

The ingredients in Pure Inositol Crystals interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Pure Inositol Crystals interact with drugs. Each result below shows which ingredient is responsible. Inositol Crystals

Each ingredient & the kinds of drugs it affects

For each ingredient in Pure Inositol Crystals with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Inositol Crystals1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that inositol lowers blood glucose levels and glycated hemoglobin (HbA1c) levels in patients with diabetes.

Likelihood Possible Evidence A
Inositol Crystals full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pure Inositol Crystals, from the product label.

Source Naturals

Name
Source Naturals, Inc.
Street Address
P. O. Box 2118
City
Santa Cruz
State
CA
ZipCode
95062
Web Address
www.sourcenaturals.com
Pharmacist Counseling Corner

Pure Inositol Crystals by Source Naturals: Common Questions

Does Pure Inositol Crystals by Source Naturals interact with any medications?
Yes. Based on its ingredients, Pure Inositol Crystals has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pure Inositol Crystals contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will inositol help my PCOS or metabolic syndrome?
Inositol has possibly effective evidence for both PCOS and metabolic syndrome, meaning some research supports benefit but the evidence isn't definitive. Talk with your doctor about whether it fits into your treatment plan.
What side effects should I watch for?
Most common side effects are digestive: diarrhea, gas, and nausea. These tend to be mild. In rare cases, when inositol was combined with omega-3s in children, cold and allergy symptoms were reported.
Is it safe to take while pregnant?
Inositol is rated possibly safe in pregnancy, but safety hasn't been fully established. It's been studied in pregnancy for certain conditions, but only use it under your doctor's supervision.
What if I'm breastfeeding?
We don't have enough reliable information on file about inositol and breastfeeding. Check with your doctor or pharmacist before taking it.
Does it help with anxiety or depression?
The evidence rates inositol as possibly ineffective for both anxiety and depression, so the data doesn't support using it for those purposes.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pure Inositol Crystals is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pure Inositol Crystals label
Go deeper

The Full Monographs Behind Pure Inositol Crystals’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Inositol

Interacts with 86 drugs

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, mood, and metabolic concerns. The stronge...

Read the full Inositol monograph →
Sources

Sources & How We Checked

Pure Inositol Crystals's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Inositol 14 references
  1. Palatnik A, Frolov K, Fux M, Benjamin J. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. J Clin Psychopharmacol 2001;21:335-9.. PubMed
  2. Allan SJ, Kavanagh GM, Herd RM, Savin JA. The effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trial. Br J Dermatol 2004;150:966-9. PubMed
  3. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  4. Kamenov Z, Kolarov G, Gateva A, Carlomagno G, Genazzani AD. Ovulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance. Gynecol Endocrinol 2015;31(2):131-5. PubMed
  5. Matarrelli B, Vitacolonna E, D'Angelo M, et al. Effect of dietary myo-inositol supplementation in pregnancy on the incidence of maternal gestational diabetes mellitus and fetal outcomes: a randomized controlled trial. J Matern Fetal Neonatal Med 2013;26(1 PubMed
  6. Mukai T, Kishi T, Matsuda Y, Iwata N. A meta-analysis of inositol for depression and anxiety disorders. Hum Psychopharmacol 2014;29(1):55-63. PubMed
  7. Farren M, Daly N, McKeating A, Kinsley B, Turner MJ, Daly S. The Prevention of Gestational Diabetes Mellitus With Antenatal Oral Inositol Supplementation: A Randomized Controlled Trial. Diabetes Care. 2017;40(6):759-63. PubMed
  8. Zheng X, Liu Z, Zhang Y, et al. Relationship Between Myo-Inositol Supplementary and Gestational Diabetes Mellitus: A Meta-Analysis. Medicine (Baltimore). 2015;94(42):e1604. PubMed
  9. Crawford TJ, Crowther CA, Alsweiler J, Brown J. Antenatal dietary supplementation with myo-inositol in women during pregnancy for preventing gestational diabetes. Cochrane Database Syst Rev. 2015;(12):CD011507. PubMed
  10. Maurizi AR, Menduni M, Del Toro R, et al. A pilot study of D-chiro-inositol plus folic acid in overweight patients with type 1 diabetes. Acta Diabetol. 2017;54(4):361-65. PubMed
  11. Leppink EW, Redden SA, Grant JE. A double-blind, placebo-controlled study of inositol in trichotillomania. Int Clin Psychopharmacol. 2017;32(2):107-14. PubMed
  12. Lam S, Mandrekar SJ, Gesthalter Y. A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia. Cancer Prev Res (Phila). 2016;9(12):906-14.
  13. Wozniak J, Faraone SV, Chan J, et al. A randomized clinical trial of high eicosapentaenoic acid omega-3 fatty acids and inositol as monotherapy and in combination in the treatment of pediatric bipolar spectrum disorders: a pilot study. J Clin Psychiatry. PubMed
  14. Vitale SG, Corrado F, Caruso S, et al. Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-

See these in context on the Inositol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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