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Dietary supplement

Pure Liquid Clear NuStevia Ingredients & Drug Interactions

by NuNaturals

Pure Liquid Clear NuStevia label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pure Liquid Clear NuStevia against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Pure Liquid Clear NuStevia is a dietary supplement by NuNaturals with 1 active ingredient. Its ingredients are commonly taken for sugar substitute / sweetener, blood sugar support in diabetes, weight management.Based on those ingredients, 259 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are NuStevia(R) extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Pure Liquid Clear NuStevia by NuNaturals

Ask about any prescription or over-the-counter medication and we check it for interactions with Pure Liquid Clear NuStevia by NuNaturals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Pure Liquid Clear NuStevia by NuNaturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Pure Liquid Clear NuStevia contains one active ingredient: NuStevia extract, a sweetener made from the stevia plant. This liquid form also includes water, grain alcohol, vegetable glycerin, and natural flavors as inactive ingredients to deliver the sweetener in liquid form.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Stevia product and its label doesn't state a use — see Stevia's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold doesn't establish whether stevia works for diabetes, high blood pressure, or weight management—the ratings for all three are insufficient reliable evidence. Some early research in people with type 2 diabetes suggests a single dose may lower blood sugar after eating, but other studies don't show this effect clearly.

We simply don't have enough solid data to say whether this product is effective for these uses.

The evidence, ingredient by ingredient Stevia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Purified stevia sweeteners like this one are generally recognized as safe in the amounts typically used in food. At supplement doses, however, safety data is limited, so use caution.

Side effects are generally mild and well tolerated—the most common are bloating, dizziness, headache, muscle pain, nausea, and numbness, most of which tend to resolve within the first week. Serious allergic reactions are rare.

Data on stevia's safety during pregnancy and breastfeeding isn't on file, so talk with your doctor or pharmacist before using it if you're pregnant or nursing.

Side effects, ingredient by ingredient Stevia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Stevia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 259 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take lithium, check with your doctor or pharmacist first—stevia may raise lithium levels. Also double-check if you're on blood pressure medication or diabetes medication, as stevia might intensify their effects.

No other medication interactions are documented for this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you take lithium, blood pressure medication, or diabetes medication, talk with your doctor or pharmacist before adding this stevia product—the interactions are documented and need individual review. For most people using it as a sweetener in typical amounts, it's generally well tolerated, though full safety at higher supplement doses isn't established.

Clear your exact medications with your own healthcare provider before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pure Liquid Clear NuStevia, straight from the product label.

Brand NuNaturals
Barcode (UPC) 739223001517
Net contents 2 fl. Oz.; 59 mL
Market status On market
Date entered into DSLD May 22, 2015
DSLD ID 45076
Product type Botanical
Supplement form Liquid
Dietary claims / uses No Claim
Intended target group(s) Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pure Liquid Clear NuStevia by NuNaturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.25 mL
Maximum serving Sizes:
0.5 mL
Servings per container
236
UPC/BARCODE
739223001517
IngredientAmount% DV
NuStevia(R) extract200 mg--

Other ingredients: Water, 20% pure Grain Alcohol, Vegetable Glycerin, Natural Flavors

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: Shake before using. As a dietary supplement, use 5-10 drops directly in your favorite food or beverage.

Formula

NuNaturals uses our highly concentrated NuStevia extract and should not be confused with less potent powdered herbs or extracts.

Formulation

Contains no msg, soy, milk, synthetics, artificial colors or flavors, preservatives, saccharin, aspartame, sucralose, or artificial sweeteners.

Zero Calories

General

V3

General Statements

NuNaturals uses plant-based natural flavors that help to make our Stevia products the best-tasting ones available. NuStevia brand Stevia is a natural plant extract. NuStevia is a non-bitter extract with no unpleasant after taste.

Non-Bitter

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pure Liquid Clear NuStevia by NuNaturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pure Liquid Clear NuStevia label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pure Liquid Clear NuStevia by NuNaturals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.25 mL Dosage formLiquid Servings per container236 Amounts shown are per serving.

NuStevia(R) extract

Interacts with
259 drugs
200 mg per serving

Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regu...

NuStevia(R) extract monograph & interactions

Other (inactive) ingredients: Water, 20% pure Grain Alcohol, Vegetable Glycerin, Natural Flavors. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pure Liquid Clear NuStevia by NuNaturals Drug Interactions

Want to check YOUR meds against Pure Liquid Clear NuStevia?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
259Drugs
1 Moderate 258 Minor

Ingredients driving the most interactions

NuStevia(R) extract 259

Individual Drug Interactions

The ingredients in Pure Liquid Clear NuStevia interact with 259 drugs. Click any drug to see the details.

1 of the 1 ingredient in Pure Liquid Clear NuStevia interact with drugs. Each result below shows which ingredient is responsible. NuStevia(R) extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Pure Liquid Clear NuStevia with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

NuStevia(R) extract3 drug types · 259 drugs

Lithium

Theoretically, stevia might decrease clearance and increase levels of lithium.
Animal research suggests that stevia extracts might have diuretic activity. Theoretically, increased reabsorption of lithium along with sodium might reduce excretion and increase levels of lithium.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Preliminary clinical research in patients with type 2 diabetes suggests that taking a single dose of stevia extract 1000 mg reduces postprandial blood glucose levels when taken with a meal. However, other clinical research in patients with type 1 or type 2 diabetes suggests that taking stevioside 250 mg three times daily does not significantly affect blood glucose levels or glycated hemoglobin (HbA1C) after three months of treatment.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Stevia extract and stevioside might lower blood pressure in patients with hypertension. However, other clinical research suggests that stevioside does not significantly lower blood pressure in patients with hypertension.

Likelihood Possible Evidence D
NuStevia(R) extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pure Liquid Clear NuStevia, from the product label.

NuNaturals

See all NuNaturals products
Name
NuNaturals, Inc.
Street Address
2220 West 2nd Ave.
City
Eugene
State
Oregon
ZipCode
97402
Phone Number
800-753-4372
Web Address
www.nunaturals.com
Pharmacist Counseling Corner

Pure Liquid Clear NuStevia by NuNaturals: Common Questions

Does Pure Liquid Clear NuStevia by NuNaturals interact with any medications?
Yes. Based on its ingredients, Pure Liquid Clear NuStevia has a known interaction with 259 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pure Liquid Clear NuStevia contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What are the most common side effects?
Bloating, dizziness, headache, muscle pain, nausea, and numbness are the most common mild effects people report. Most of these resolve within the first week of use. Serious allergic reactions are rare.
Is this safe to use while pregnant or breastfeeding?
We don't have safety data on file for stevia during pregnancy or breastfeeding. Talk with your doctor or pharmacist about whether it's right for you in that situation—they can weigh what we know and your individual health picture.
Is this a natural sweetener?
Yes, it's made from stevia plant extract. It's purified stevia in liquid form with water, grain alcohol, vegetable glycerin, and natural flavors.
Will stevia help me lose weight or lower my blood sugar?
We don't have enough reliable evidence to say whether stevia works for weight loss or blood sugar control. Early research in people with type 2 diabetes is mixed, so don't assume it will help without talking to your doctor first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pure Liquid Clear NuStevia is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pure Liquid Clear NuStevia label
Go deeper

The Full Monographs Behind Pure Liquid Clear NuStevia’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Stevia

Interacts with 259 drugs

Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regulators. Purified stevia extracts have a...

Read the full Stevia monograph →
Sources

Sources & How We Checked

Pure Liquid Clear NuStevia's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Stevia 10 references
  1. Chan P, Xu DY, Liu JC, et al. The effect of stevioside on blood pressure and plasma catecholamines in spontaneously hypertensive rats. Life Sci 1998;63:1679-84. PubMed
  2. Melis MS. A crude extract of Stevia rebaudiana increases the renal plasma flow of normal and hypertensive rats. Braz J Med Biol Res 1996;29:669-75.
  3. Melis MS. Chronic administration of aqueous extract of Stevia rebaudiana in rats: renal effects. J Ethnopharmacol 1995;47:129-34. PubMed
  4. Melis MS, Sainati AR. Effect of calcium and verapamil on renal function of rats during treatment with stevioside. J Ethnopharmacol 1991;33:257-622. PubMed
  5. Hsieh MH, Chan P, Sue YM, et al. Efficacy and tolerability of oral stevioside in patients with mild essential hypertension: a two-year, randomized, placebo-controlled study. Clin Ther 2003;25:2797-808. PubMed
  6. Chan P, Tomlinson B, Chen YJ, et al. A double-blind placebo-controlled study of the effectiveness and tolerability of oral stevioside in human hypertension. Br J Clin Pharmacol 2000;50:215-20. PubMed
  7. Gregersen S, Jeppesen PB, Holst JJ, Hermansen K. Antihyperglycemic effects of stevioside in type 2 diabetic subjects. Metabolism 2004;53:73-6. PubMed
  8. Barriocanal LA, Palacios M, Benitez G, et al. Apparent lack of pharmacological effect of steviol glycosides used as sweeteners in humans. A pilot study of repeated exposures in some normotensive and hypotensive individuals and in Type 1 and Type 2 diabeti
  9. Ferri LA, Alves-Do-Prado W, Yamada SS, et al. Investigation of the antihypertensive effect of oral crude stevioside in patients with mild essential hypertension. Phytother Res 2006;20:732-6. PubMed
  10. Almiron-Roig E, Navas-Carretero S, Castelnuovo G, et al. Impact of acute consumption of beverages containing plant-based or alternative sweetener blends on postprandial appetite, food intake, metabolism, and gastro-intestinal symptoms: Results of the SWEE

See these in context on the Stevia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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