No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Pygeum Ingredients & Drug Interactions

by Herbal Terra

Liquid Category: Botanical
No known interaction
The interaction bottom line No known interaction

Pygeum is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, urinary symptoms in men, prostate health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Pygeum by Herbal Terra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Herbal Terra's Pygeum is a single-ingredient liquid extract made from the dried bark of Prunus africana, an African plum tree. The extract is certified organic and suspended in a menstruum (a liquid used to dissolve and carry herbal active compounds).

That's it — one active ingredient, no other botanicals mixed in.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: prostate health and urinary function.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), prostate symptoms, urinary flow.
  • The strongest evidence on file: Pygeum is rated "Likely Effective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).

Pygeum is likely effective for benign prostatic hyperplasia (BPH) — the non-cancerous enlargement of the prostate that causes urinary symptoms in many men. For other uses listed in research — Alzheimer disease, malaria, sexual desire, and psychosis — the evidence isn't established well enough to rate it.

If you're considering this for BPH, it may help; for anything else, the data doesn't support a reliable benefit yet.

The evidence, ingredient by ingredient Pygeum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pygeum is generally well tolerated in the short term, but good long-term safety data are thin. A small number of trial participants reported nausea and abdominal pain, though the rate was similar to placebo, so they weren't clearly linked to the herb itself.

The safety data advises against use in pregnancy because it's meant for men's prostate health and hasn't been tested safely in pregnant people. There isn't enough safety information for breastfeeding, so it's best avoided then too.

Side effects, ingredient by ingredient Pygeum

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we checked. Still, use the medication search tool on this page for your exact prescriptions before starting, and confirm with your own doctor or pharmacist that Pygeum is safe to add alongside everything else you take.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

If you're a man with BPH symptoms, Pygeum may be worth trying — it has solid evidence backing it for that use. If you're taking any medications, run them through the checker on this page before you start, and mention it to your doctor or pharmacist to confirm it fits your health picture.

Avoid it if you're pregnant or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pygeum, straight from the product label.

Brand Herbal Terra
Barcode (UPC) 7429524334355
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Sep 25, 2020
DSLD ID 234139
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pygeum by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
7429524334355
IngredientAmount% DV
certified organic Pygeum (Prunus africana) dried bark liquid extract970 mg--

Other ingredients: Menstruum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Origin of plant material: Madagascar.

Manufactured in the USA in an FDA registered facility

Sugar free

Dried herb/menstruum ratio: 1:3 Expertly extracted Laboratory tested 330 mg/1 mL Premium product Super concentrated liquid herbal extract

Non GMO

No artificial ingredients, GMO, gluten, color additives, fillers, preservatives or binders. Natural Gluten Free

Suggested/Recommended/Usage/Directions

Direction Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz of juice or water up to 4 times a day. We recommend to seek expert medical advice before taking this or any other herbal supplements.

FDA Disclaimer Statement

Notice This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Caution May have contraindications.

Do not use if you are allergic to any ingredients.

Consult a physician before using during pregnancy, if nursing, or if you are on any medications.

Keep out of the reach of children.

Storage

Store in a cool, dry, dark place.

Formula

Prunus africana

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Made in USA Made in an FDA registered facility Natural Gluten Free

See for yourself

Pygeum by Herbal Terra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pygeum by Herbal Terra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

970 mg per serving

Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some st...

Certified organic Pygeum (Prunus africana) dried bark liquid extract monograph & interactions

Other (inactive) ingredients: Menstruum. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pygeum by Herbal Terra Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Pygeum. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Pygeum, from the product label.

Herbal Terra

See all Herbal Terra products
Name
Herbal Terra
Pharmacist Counseling Corner

Pygeum by Herbal Terra: Common Questions

Does Pygeum by Herbal Terra interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Pygeum. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Pygeum contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does Pygeum really help with prostate problems?
It's likely effective for benign prostatic hyperplasia — the non-cancerous swelling of the prostate that causes urinary trouble. That's the main evidence-backed use. For other concerns, we don't have enough reliable data.
What side effects should I watch for?
Nausea and abdominal pain have been reported in some people taking pygeum in trials, but they showed up at about the same rate as placebo, so they weren't clearly caused by the herb. Most people tolerate it well short-term, though long-term safety data are limited.
Is this safe to take long-term?
Pygeum is generally well tolerated in the short term, but we don't have strong safety data for long-term use. If you're thinking of taking it for months or years, talk it over with your doctor or pharmacist about what we know and don't know.
Can I take this if I'm pregnant or breastfeeding?
No. Pygeum is used for men's prostate health and has no established safe use in pregnancy. There isn't enough safety information for breastfeeding either, so it's best avoided then.
What's in the liquid besides the pygeum?
The extract is mixed with menstruum, which is a liquid carrier that dissolves and delivers the active compounds from the bark. That's the only other ingredient — no fillers or extra botanicals.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pygeum is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pygeum label
Go deeper

The Full Monographs Behind Pygeum’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Pygeum's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pygeum 3 references
  1. Ishani A, MacDonald R, Nelson D, et al. Pygeum africanum for the treatment of patients with benign prostatic hyperplasia: a systematic review and quantitative meta-analysis. Am J Med 2000;109:654-64.. PubMed
  2. Wilt T, Ishani A, Mac Donald R, et al. Pygeum africanum for benign prostatic hyperplasia. Cochrane Database Syst Rev 2002;CD001044.. PubMed
  3. Andro M and Riffaud J. Pygeum africanum extract for the treatment of patients with benign prostatic hyperplasia: a review of 25 years of published experience. Curr Ther Res 1995;56(8):796-817. DOI

See these in context on the Pygeum monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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