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Dietary supplement

R3 Extra Strength Ingredients & Drug Interactions

by elon

R3 Extra Strength label
See full label image
Tablet Or Pill Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking R3 Extra Strength against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

R3 Extra Strength is a dietary supplement by elon with 4 active ingredients. Its ingredients are commonly taken for hair, skin, and nail health, bone health and osteoporosis, joint and connective tissue support.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Cysteine Hydrochloride. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against R3 Extra Strength by elon

Ask about any prescription or over-the-counter medication and we check it for interactions with R3 Extra Strength by elon — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of R3 Extra Strength by elon

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Elon R3 Extra Strength contains 4 active ingredients. Silicon dioxide is a form of silicon, a mineral found naturally in plants and water.

Biotin is a B vitamin your body uses to break down food for energy and maintain healthy skin and hair. Fish collagen peptides are a protein derived from fish, added as a dietary protein source.

L-cysteine hydrochloride is an amino acid — a building block of protein — supplied in a supplemental form. The tablet also contains inactive ingredients (binders, fillers, and capsule materials): dicalcium phosphate, hydroxypropyl methylcellulose, stearic acid, microcrystalline cellulose, magnesium stearate, titanium dioxide, triacetin, and natural flavor.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Supports healthy hair, skin, and nails.
  • We looked for evidence on: Acne, Aging skin, Alopecia areata, Androgenic alopecia, Atopic dermatitis (eczema), Biotin deficiency — and 4 related terms.
  • The strongest evidence on file: Biotin is rated "Likely Effective" for Biotin deficiency (Natural Medicines).
  • Also on file: Collagen Peptides is rated "Possibly Effective" for Aging skin, Dry skin.
  • Also on file: Biotin is rated "Possibly Ineffective" for Seborrheic dermatitis.

The evidence for this product's ingredients is mixed. Silicon is possibly effective for osteoporosis, but evidence for its use in hair loss (androgenic alopecia) and other conditions is insufficient.

Biotin is likely effective for biotin deficiency, but evidence suggests it is possibly ineffective for multiple sclerosis and seborrheic dermatitis; evidence for alopecia areata is insufficient. Fish collagen peptides are possibly effective for aging and dry skin, but possibly ineffective for muscle strength; evidence for acne and athletic performance is insufficient.

L-cysteine has insufficient evidence for hair loss, leg ulcers, hangover, stroke, and gastritis. Overall, the strongest claim the ingredients carry is for biotin deficiency and silicon for osteoporosis.

The evidence, ingredient by ingredient Silicon Biotin Collagen Peptides L-cysteine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Silicon dioxide, biotin, and fish collagen peptides are generally well tolerated. Silicon is generally well tolerated at the amounts found in food and supplements, though long-term safety at high doses is not well studied.

Biotin is safe even at fairly high doses because excess is removed through urine; only rare mild diarrhea has been reported at very high doses. Fish collagen peptides may rarely cause nausea, indigestion, diarrhea, or bloating.

L-cysteine is generally well tolerated in food amounts, but long-term safety of supplement doses is not well studied. For pregnancy and breastfeeding: silicon dioxide and biotin are rated likely safe in normal amounts.

Fish collagen peptides have not been well studied in pregnancy or breastfeeding — talk with your doctor before using if you're pregnant or nursing. L-cysteine is rated likely safe in pregnancy and lactation, though data are limited.

Side effects, ingredient by ingredient Silicon Biotin Collagen Peptides L-cysteine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 4 matched ingredients can interact with medications — L-cysteine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs (medications for diabetes or low blood sugar), check with your doctor or pharmacist before starting this product — L-cysteine may theoretically increase the risk of low blood sugar. For all other medications, no interactions are documented for the ingredients we could check, though that is not a guarantee none exist.

Use the search tool below to look up your exact medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Elon R3 Extra Strength is a four-ingredient supplement combining silicon, biotin, fish collagen, and L-cysteine for hair, skin, and possibly bone health. If you take diabetes medication, check with your doctor or pharmacist before starting, because L-cysteine may theoretically lower blood sugar further.

The evidence for most conditions is weak or mixed; biotin deficiency and osteoporosis have the strongest support. Talk it over with your doctor or pharmacist to see if it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about R3 Extra Strength, straight from the product label.

Brand elon
Barcode (UPC) 058869127017
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD Aug 23, 2023
DSLD ID 293479
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for R3 Extra Strength by elon, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
Servings per container
30
UPC/BARCODE
058869127017
IngredientAmount% DV
Silicon Dioxide100 mg--
Biotin5000 mcg16667%
Fish Collagen Peptides600 mg--
L-Cysteine Hydrochloride50 mg--

Other ingredients: Dicalcium Phosphate, Hydroxypropyl Methylcellulose, Stearic Acid, Microcrystalline Cellulose, Magnesium Stearate, Titanium Dioxide, Triacetin, Natural flavor

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Supports healthy hair, skin, and nails

Revitalize, rejuvenate, & restore

Healthier, thicker hair Extended-release

Formulated in USA

Formula

Three essential nutritional building blocks, as well as fish collagen peptides, promote hair strength, luster, and body from the root. Added benefits include healthy nail growth and more youthful looking skin.

Seals/Symbols

Made in the USA

FDA Statement of Identity

Dietary Supplement

General Statements

Dermatologist recommended

Precautions

Contains: Fish (tilapia, pangasius, trout, ling, cod, haddock, salmon, channel and atlantic catfish).

Caution: Do not exceed recommended serving size.

Keep out of reach of children.

Do not use if safety seal is damaged.

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take two (2) tablets daily.

Storage

Store in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

R3 Extra Strength by elon label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

R3 Extra Strength label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in R3 Extra Strength by elon

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Silicon Dioxide

No known
interactions
100 mg per serving

Silicon is a trace mineral found in the body and in foods like oats, barley, and certain fruits and vegetables, and it is popular in supplements for h...

Silicon Dioxide monograph & interactions

Biotin

No known
interactions
5000 mcg per serving

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...

Biotin monograph & interactions

Fish Collagen Peptides

No known
interactions
600 mg per serving

Collagen peptides are a well-absorbed form of protein that may modestly improve skin elasticity and joint comfort for some people, though evidence is...

Fish Collagen Peptides monograph & interactions

L-Cysteine Hydrochloride

Interacts with
86 drugs
50 mg per serving

L-cysteine is a sulfur-containing amino acid your body uses to make proteins and the antioxidant glutathione. Most people get enough from food, and su...

L-Cysteine Hydrochloride monograph & interactions

Other (inactive) ingredients: Dicalcium Phosphate, Hydroxypropyl Methylcellulose, Stearic Acid, Microcrystalline Cellulose, Magnesium Stearate, Titanium Dioxide, Triacetin, Natural flavor. These complete the product’s ingredient list but are not active constituents.

Interaction report

R3 Extra Strength by elon Drug Interactions

Want to check YOUR meds against R3 Extra Strength?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

L-Cysteine Hydrochloride 86

Individual Drug Interactions

The ingredients in R3 Extra Strength interact with 86 drugs. Click any drug to see the details.

1 of the 4 ingredients in R3 Extra Strength interact with drugs. Each result below shows which ingredient is responsible. L-Cysteine Hydrochloride

Each ingredient & the kinds of drugs it affects

For each ingredient in R3 Extra Strength with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Cysteine Hydrochloride1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that L-cysteine can have hypoglycemic effects.

Likelihood Possible Evidence D
L-Cysteine Hydrochloride full monograph & interactions
The maker

Brand information

Manufacturer and brand details for R3 Extra Strength, from the product label.

elon

See all elon products
Name
Dartmouth Pharmaceuticals
Street Address
1828 Touby Pike
City
Kokomo
State
IN
ZipCode
46901
Phone Number
800-414-3566
Web Address
www.elonessentials.com
Pharmacist Counseling Corner

R3 Extra Strength by elon: Common Questions

Does R3 Extra Strength by elon interact with any medications?
Yes. Based on its ingredients, R3 Extra Strength has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
R3 Extra Strength contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help with hair loss?
The evidence for all four ingredients on hair loss and baldness is either insufficient or not yet established. Biotin and L-cysteine have insufficient evidence; silicon and collagen peptides lack adequate research specifically for hair loss. Talk with your doctor if you're looking for treatment options with stronger evidence.
Is biotin safe to take every day?
Yes — biotin is generally considered safe even at fairly high doses because your body removes excess through urine. Mild diarrhea has been reported rarely at very high doses. Normal supplement amounts carry a good safety profile.
Can I take this while pregnant?
Silicon dioxide and biotin are rated likely safe at normal amounts in pregnancy. Fish collagen peptides haven't been well studied in pregnancy, so check with your doctor first. L-cysteine is rated likely safe, though data are limited. Always discuss supplements with your doctor when you're pregnant or planning to be.
What does L-cysteine do?
L-cysteine is an amino acid — a building block of protein. The product claims relate to hair, skin, nails, and detoxification, but evidence for these uses is insufficient or not yet established.
Are there any fillers or unnecessary ingredients?
The tablet contains inactive ingredients typical of supplements: binders, fillers, and flow agents like microcrystalline cellulose, magnesium stearate, and dicalcium phosphate. These are standard for making tablets and don't add active benefit, but they're necessary for the tablet to hold together and release properly.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if R3 Extra Strength is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

R3 Extra Strength label
Go deeper

The Full Monographs Behind R3 Extra Strength’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Silicon

Silicon is a trace mineral found in the body and in foods like oats, barley, and certain fruits and vegetables, and it is popular in supplements for hair, skin, nail, and bone health. Some s...

Read the full Silicon monograph → Herb & supplement monograph

Biotin

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get plenty from a normal diet, and true defi...

Read the full Biotin monograph → Herb & supplement monograph

Collagen Peptides

Collagen peptides are a well-absorbed form of protein that may modestly improve skin elasticity and joint comfort for some people, though evidence is still developing and results vary. They...

Read the full Collagen Peptides monograph → Herb & supplement monograph

L-cysteine

Interacts with 86 drugs

L-cysteine is a sulfur-containing amino acid your body uses to make proteins and the antioxidant glutathione. Most people get enough from food, and supplements are usually well tolerated, bu...

Read the full L-cysteine monograph →
Sources

Sources & How We Checked

R3 Extra Strength's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 27 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Silicon 19 references
  1. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  2. Jugdaohsingh R, Anderson SH, Tucker KL, et al. Dietary silicon intake and absorption. Am J Clin Nutr 2002;75:887-93. PubMed
  3. Ichiyanagi O, Sasagawa I, Adachi Y, et al. Silica urolithiasis without magnesium trisilicate intake. Urol Int 1998;61:39-42. PubMed
  4. Levison DA, Crocker PR, Banim S, Wallace DM. Silica stones in the urinary bladder. Lancet 1982;1:704-5. PubMed
  5. Lee MH, Lee YH, Hsu TH, et al. Silica stone--development due to long time oral trisilicate intake. Scand J Urol Nephrol 1993;27:267-9. PubMed
  6. Cruz Guerra, N. A., Gomez Garcia, M. A., Lovaco, Castellano F., Saez Garrido, J. C., Garcia, Cuerpo E., and Escudero, Barrilero A. [Silica urolithiasis: report of a new case]. Actas Urol.Esp 2000;24(2):202-204.
  7. Merget, R., Bauer, T., Kupper, H. U., Philippou, S., Bauer, H. D., Breitstadt, R., and Bruening, T. Health hazards due to the inhalation of amorphous silica. Arch Toxicol. 2002;75(11-12):625-634. PubMed
  8. Khuder, S. A., Peshimam, A. Z., and Agraharam, S. Environmental risk factors for rheumatoid arthritis. Rev Environ Health 2002;17(4):307-315. PubMed
  9. McLaughlin, J. K., Chow, W. H., and Levy, L. S. Amorphous silica: a review of health effects from inhalation exposure with particular reference to cancer. J Toxicol.Environ Health 4-25-1997;50(6):553-566. DOI
  10. Pelucchi, C., Pira, E., Piolatto, G., Coggiola, M., Carta, P., and La, Vecchia C. Occupational silica exposure and lung cancer risk: a review of epidemiological studies 1996-2005. Ann.Oncol. 2006;17(7):1039-1050. PubMed
  11. Gillissen, A., Gessner, C., Hammerschmidt, S., Hoheisel, G., and Wirtz, H. [Health significance of inhaled particles]. Dtsch.Med Wochenschr. 3-24-2006;131(12):639-644.
  12. Hu, J. F., Qu, H., and Wang, J. Z. [Meta analysis for relationship between exposure of free silicon dioxide and lung tumor]. Zhonghua Lao.Dong.Wei Sheng Zhi.Ye.Bing.Za Zhi. 2006;24(7):415-417.
  13. Jugdaohsingh, R. Silicon and bone health. J Nutr Health Aging 2007;11(2):99-110.
  14. Lacasse, Y., Martin, S., Gagne, D., and Lakhal, L. Dose-response meta-analysis of silica and lung cancer. Cancer Causes Control 2009;20(6):925-933. PubMed
  15. McCormic, Z. D., Khuder, S. S., Aryal, B. K., Ames, A. L., and Khuder, S. A. Occupational silica exposure as a risk factor for scleroderma: a meta-analysis. Int Arch Occup.Environ Health 2010;83(7):763-769. PubMed
  16. Haddad, F. S. and Kouyoumdjian, A. Silica stones in humans. Urol.Int 1986;41(1):70-76. PubMed
  17. Tervaert, J. W., Stegeman, C. A., and Kallenberg, C. G. Silicon exposure and vasculitis. Curr Opin.Rheumatol 1998;10(1):12-17. PubMed
  18. Steenland, K. and Stayner, L. Silica, asbestos, man-made mineral fibers, and cancer. Cancer Causes Control 1997;8(3):491-503. PubMed
  19. Boqué N, Valls RM, Pedret A, Puiggrós F, Arola L, Solà R. Relative absorption of silicon from different formulations of dietary supplements: a pilot randomized, double-blind, crossover post-prandial study. Sci Rep 2021;11(1):16479. PubMed

See these in context on the Silicon monograph →

Biotin 4 references
  1. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
  4. Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed

See these in context on the Biotin monograph →

Collagen Peptides 2 references
  1. Trc T, Bohmová J. Efficacy and tolerance of enzymatic hydrolysed collagen (EHC) vs. glucosamine sulphate (GS) in the treatment of knee osteoarthritis (KOA). Int Orthop. 2011;35(3):341-8. PubMed
  2. Evans M, Lewis ED, Zakaria N, Pelipyagina T, Guthrie N. A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity. J Cosmet Dermatol. 2021;20(3):825-834. PubMed

See these in context on the Collagen Peptides monograph →

L-cysteine 2 references
  1. Dowlati Y, Maheux M, Meyer JH. The effect of oral L-cysteine on breast milk and plasma cysteine concentrations. Neuropsychiatr Dis Treat 2020;16:3163-3172.
  2. Lee S, Han KH, Nakamura Y, et al. Dietary L-cysteine improves the antioxidative potential and lipid metabolism in rats fed a normal diet. Biosci Biotechnol Biochem 2013;77(7):1430-4.

See these in context on the L-cysteine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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