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Dietary supplement

Restharrow Ingredients & Drug Interactions

by Herbal Terra

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Restharrow is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for increasing urine flow (mild diuretic), flushing the urinary tract, mild bladder and kidney complaints.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Restharrow Root Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Restharrow by Herbal Terra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Restharrow Root Extract, Dry. In herbal medicine, restharrow has traditionally been used for urinary tract and kidney concerns, though the current evidence doesn't yet support those uses in humans.

The liquid formulation also contains alcohol, water, and glycerin as inactive ingredients.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: support for urinary tract and kidney health.
  • We looked for evidence on: Kidney stones (nephrolithiasis), Urinary tract infections (UTIs), urinary flow, bladder health, fluid retention.
  • The closest evidence on file: Spiny Restharrow is rated "Insufficient Reliable Evidence To Rate" for Kidney stones (nephrolithiasis) (Natural Medicines).
  • Also on file: Spiny Restharrow is rated "Insufficient Reliable Evidence To Rate" for Urinary tract infections (UTIs).

The evidence for restharrow isn't established yet in our data. The product has been used traditionally for benign prostatic hyperplasia (enlarged prostate), kidney stones, urinary tract infections, and gastritis, but we don't have reliable human trial evidence to confirm it works for any of these.

If you're considering it for one of these reasons, that's a conversation worth having with your pharmacist.

The evidence, ingredient by ingredient Spiny Restharrow

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Restharrow is generally regarded as traditionally used, but human safety data are limited. The product should be avoided during pregnancy—there isn't enough safety information to recommend it.

Safety while breastfeeding is also unknown, so you should avoid it then too. No adverse effects were reported in the data we hold, but the overall safety profile in people hasn't been thoroughly studied.

Side effects, ingredient by ingredient Spiny Restharrow

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Spiny Restharrow.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take lithium for mood disorders, double-check before using this product—restharrow may raise lithium levels and strengthen its effects.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

Restharrow is a traditional herbal remedy with limited human safety data and unproven effectiveness for its common uses. If you take lithium, you'll need to check with your pharmacist first.

Pregnant or breastfeeding? Skip this one.

A conversation with your pharmacist can help you decide if it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Restharrow, straight from the product label.

Brand Herbal Terra
Barcode (UPC) 6175033260722
Net contents 2 Fluid Ounce(s); 60 mL
Market status On market
Date entered into DSLD Jan 23, 2025
DSLD ID 325342
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Restharrow by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
60
UPC/BARCODE
6175033260722
IngredientAmount% DV
Restharrow Root Extract, Dry983 mg--

Other ingredients: Alcohol, Water, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz. of juice or water up to 4 times a day.

Precautions

We recommend to seek expert medical advice before taking. May have contraindications and cause adverse reaction.

Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications.

Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications. Keep out of the reach of children!

Do not use if you are allergic to any ingredients.

Storage

Store in a cool, dry, dark place.

FDA Disclaimer Statement

This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.

Formulation

cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.

Sugar free

Expertly extracted 100% natural Premium product

Organic alcohol

No artificial ingredients, color additives, fillers or binders.

Natural Gluten free

Formula

Ononis spinosa

Organic alcohol

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Made in USA

General Statements

Organic raw material.

See for yourself

Restharrow by Herbal Terra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Restharrow by Herbal Terra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.

Restharrow Root Extract, Dry

Interacts with
1 drug
983 mg per serving Form: Ononis spinosa Root Extract, Dry

Spiny Restharrow is a traditional European herb whose root has long been used as a mild diuretic to help flush the urinary tract. Solid human evidence...

Restharrow Root Extract, Dry monograph & interactions

Other (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Restharrow by Herbal Terra Drug Interactions

Want to check YOUR meds against Restharrow?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1Drugs
1 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Restharrow with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Restharrow Root Extract, Dry1 drug type · 1 drug

Lithium

Theoretically, spiny restharrow might increase the levels and clinical effects of lithium.
Spiny restharrow is thought to have diuretic properties. Although animal studies suggest that spiny restharrow reduces edema, diuretic activity has not been reported or evaluated in humans. Theoretically, due to these potential diuretic effects, spiny restharrow might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Restharrow, from the product label.

Herbal Terra

See all Herbal Terra products
Name
Herbal Terra LLC
Phone Number
+18083857868
Web Address
herbalterra.com
Pharmacist Counseling Corner

Restharrow by Herbal Terra: Common Questions

Does Restharrow by Herbal Terra interact with any medications?
Yes. Based on its ingredients, Restharrow has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Restharrow contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I use Restharrow if I'm pregnant or breastfeeding?
No. There isn't enough safety information during pregnancy, so it's best avoided. Safety while breastfeeding is unknown, so you should avoid it then too. Talk to your pharmacist or doctor about safer options.
Does Restharrow actually work for UTIs or kidney stones?
We don't have reliable evidence yet. Restharrow has been used traditionally for these, but human studies haven't confirmed whether it actually works. Your pharmacist can talk through what the current evidence supports.
What is restharrow root used for?
In traditional herbal medicine, it's been used for urinary tract and kidney concerns—like UTIs, kidney stones, and an enlarged prostate—as well as stomach inflammation. That said, we don't have strong human evidence for any of these yet.
Does this product have any fillers?
It does contain inactive ingredients: alcohol, water, and glycerin. These help deliver the active ingredient but aren't the therapeutic part of the product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Restharrow is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Restharrow label
Sources

Sources & How We Checked

Restharrow's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Spiny Restharrow 2 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

See these in context on the Spiny Restharrow monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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