Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Sage & Aloe Throat Spray Ingredients & Drug Interactions

by Gaia Herbs

Sage & Aloe Throat Spray label
See full label image
Liquid Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Sage & Aloe Throat Spray against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Sage & Aloe Throat Spray is a dietary supplement by Gaia Herbs with 5 active ingredients. Its ingredients are commonly taken for irritable bowel syndrome (ibs), indigestion and gas, nausea.Based on those ingredients, 1,384 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Sage Leaf Extract, Freeze-Dried, Peppermint aerial parts essential oil, organic Aloe vera leaf gel dried extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Sage & Aloe Throat Spray by Gaia Herbs

Ask about any prescription or over-the-counter medication and we check it for interactions with Sage & Aloe Throat Spray by Gaia Herbs — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Sage & Aloe Throat Spray by Gaia Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 5 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (253 mg) without saying how much of each component you get.

Sage & Aloe Throat Spray contains 5 active ingredients in a proprietary blend: peppermint aerial parts essential oil, myrrh resin extract, aloe vera leaf gel dried extract, cinnamon bark essential oil, and sage leaf extract (freeze-dried). The spray also includes inactive ingredients — glycerin, water, alcohol, mint natural flavor, and xanthan gum — which serve as preservatives, solvents, and texture agents.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: throat health and immune support.
  • We looked for evidence on: Canker sores, Common cold, Cough, Dry mouth, Gingivitis, Halitosis — and 4 related terms.
  • The closest evidence on file: Ceylon Cinnamon is rated "Insufficient Reliable Evidence To Rate" for Common cold (Natural Medicines).
  • Also on file: Ceylon Cinnamon is rated "Insufficient Reliable Evidence To Rate" for Influenza.
  • Also on file: Sage is rated "Insufficient Reliable Evidence To Rate" for Dry mouth, Gingivitis.

Of the ingredients in this spray, peppermint is likely effective for irritable bowel syndrome (IBS) and possibly effective for indigestion, nausea from chemotherapy, and easing spasms during medical procedures. Aloe gel is possibly effective for acne, burns, constipation, diabetes, psoriasis, and weight management.

Sage is possibly effective for menopausal symptoms, cholesterol, and cognitive function. For myrrh and cinnamon, the evidence we hold shows insufficient data to rate most claims — myrrh is actually rated likely ineffective for schistosomiasis — and cinnamon is rated possibly ineffective for diabetes and weight management.

The evidence for this spray's specific use as a throat spray is not established in our data.

The evidence, ingredient by ingredient Peppermint Myrrh Aloe Ceylon Cinnamon Sage

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Peppermint oil is generally well tolerated, though orally it may cause abdominal pain, belching, heartburn, diarrhea, nausea, or dry mouth; rare allergic reactions including anaphylaxis have been reported. Myrrh is likely safe for short-term topical or mouth-rinse use, but oral safety is not well studied — it traditionally stimulates the uterus and should be avoided in pregnancy.

Aloe gel applied topically is generally well tolerated, but oral aloe latex carries serious risks and should not be taken during pregnancy or while breastfeeding; it may cause abdominal pain, diarrhea, and with overuse, severe potassium depletion. Cinnamon is generally well tolerated orally at food levels; some people report bloating, indigestion, or nausea, and rare cases of bleeding have been reported with high long-term doses.

Sage is generally well tolerated as a food or short-term tea but should not be used in medicinal amounts during pregnancy because of thujone content; it may cause nausea, vomiting, diarrhea, or dizziness, and rare seizures have been reported with high doses.

Side effects, ingredient by ingredient Peppermint Myrrh Aloe Ceylon Cinnamon Sage

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 5 of the 5 matched ingredients can interact with medications — Ceylon Cinnamon, Sage, Myrrh, Aloe, Peppermint.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; seizure medications; immunosuppressants / transplant drugs; diabetes medications; heart-rhythm medications.
  • For scale: 1,385 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this spray, check with your own doctor or pharmacist if you take digoxin (Lanoxin) or other heart medications — aloe carries a Major-severity risk. Also double-check if you use blood thinners like warfarin or other anticoagulants (Moderate risk from aloe and myrrh), diabetes medications (Moderate risk from myrrh, aloe, and cinnamon), blood pressure drugs (Moderate risk from cinnamon and sage), diuretics (Moderate risk from aloe), laxatives (Moderate risk from aloe), or sedating CNS depressants (Moderate risk from sage).

Additionally, peppermint, cinnamon, and sage inhibit several drug-metabolizing enzymes and may raise levels of medications processed through CYP2C9, CYP2C19, CYP2D6, CYP3A4, or P-glycoprotein — all at Moderate severity.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.

This throat spray combines several plant extracts with activity in the mouth and throat — peppermint and sage for soothing, myrrh and aloe for topical effects. However, because all five active ingredients interact with multiple medication types, anyone taking prescriptions — especially for the heart, blood clotting, blood pressure, diabetes, or mood — should run their exact medications through the search tool on this page or check with their own doctor or pharmacist before use.

The spray is intended for mouth and throat use, but aloe and myrrh carry pregnancy warnings if swallowed in quantity, so pregnant or breastfeeding people should confirm safety with their own healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sage & Aloe Throat Spray, straight from the product label.

Brand Gaia Herbs
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Jan 23, 2023
DSLD ID 273310
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sage & Aloe Throat Spray by Gaia Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 Spray(s)
Maximum serving Sizes:
4 Spray(s)
Servings per container
45
IngredientAmount% DV
Proprietary Blend253 mg--
Peppermint aerial parts essential oil0 NP--
Myrrh resin extract0 NP--
organic Aloe vera leaf gel dried extract0 NP--
Cinnamon bark essential oil0 NP--
Sage Leaf Extract, Freeze-Dried0 NP--

Other ingredients: Glycerin, Water, Alcohol, Mint natural flavor, Xanthan Gum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

New look same formula

Gaia Herbs delivers unprecedented traceability by screening every product and sharing the results online. See for yourself, and learn more about your herbs, by entering the unique ID # below at meetyourherbs.com.

Purity - Keep it clean All products are screened for pesticides, microbes & heavy metals. Integrity - Keep it real See the proof at meetyourherbs.com, the world's first herb traceability platform. Potency - Keep it strong Concentrated plant extracts provide support when you need it most. Discover our guiding truths at: Facebook Instagram @gaiaherbs

A partnership of mutual benefits Black Elderberry Syrup is produced in Tuscany, Italy, by Aboca, the herbal supplement leader in Europe since 1978. Gaia Herbs' partnership with Aboca is born from a mutual belief in sustainable product development, dedication to quality, and a deep respect for science and nature working in harmony. Aboca

Formulation

Immune Support Traditional herbs for maintaining throat health

Product of Italy

Dairy-free Gluten-free Soy-free

Formula

With Myrrh & Cinnamon

FDA Statement of Identity

Herbal Supplement

Suggested/Recommended/Usage/Directions

Suggested Use Adults spray 4 times in the back of the throat. Use up to 4 times daily. Screw sprayer onto bottle. To operate the sprayer, rotate the wand to 90 degrees, aim in the back of the throat and press the sprayer.

Precautions

Not for use during pregnancy or lactation. If you have a medical condition or take medications, please consult with your doctor before use.

Store away from children.

Use only as directed on label. Do not use if cap seal is broken.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

EST 1987 USA Integrity Purity Potency

Certified B Corporation

Brand IP Statement(s)

Gaia Herbs Connecting Plants & People Since 1987

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Sage & Aloe Throat Spray by Gaia Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Sage & Aloe Throat Spray label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Sage & Aloe Throat Spray by Gaia Herbs

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size4 Spray(s) Dosage formLiquid Servings per container45 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Other (inactive) ingredients: Glycerin, Water, Alcohol, Mint natural flavor, Xanthan Gum. These complete the product’s ingredient list but are not active constituents.

Interaction report

Sage & Aloe Throat Spray by Gaia Herbs Drug Interactions

Want to check YOUR meds against Sage & Aloe Throat Spray?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,384Drugs
1 Major 1,369 Moderate 14 Minor

Ingredients driving the most interactions

Sage Leaf Extract, Freeze-Dried 1,296
Peppermint aerial parts essential oil 796
organic Aloe vera leaf gel dried extract 461
Cinnamon bark essential oil 258
Myrrh resin extract 88

Individual Drug Interactions

The ingredients in Sage & Aloe Throat Spray interact with 1,384 drugs. Click any drug to see the details.

5 of the 5 ingredients in Sage & Aloe Throat Spray interact with drugs. Each result below shows which ingredient is responsible. Sage Leaf Extract, Freeze-Dried Peppermint aerial parts essential oil organic Aloe vera leaf gel dried extract Cinnamon bark essential oil Myrrh resin extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Sage & Aloe Throat Spray with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Sage Leaf Extract, Freeze-Dried14 drug types · 1,296 drugs

Anticholinergic Drugs

Theoretically, sage might decrease the clinical effects of anticholinergic drugs.
In vitro evidence suggests that common sage (Salvia officinalis) and Spanish sage (Salvia lavandulaefolia) can inhibit acetylcholinesterase and might increase acetylcholine levels.

Likelihood Possible Evidence D
Anticonvulsants

Theoretically, sage might interfere with the clinical effects of anticonvulsant drugs.
Some species of sage can cause convulsions when consumed in large quantities.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking sage with antidiabetes drugs might increase the risk of hypoglycemia.
In patients with polycystic ovary syndrome (PCOS) or inadequately controlled type 2 diabetes, common sage (Salvia officinalis) has demonstrated hypoglycemic activity. However, other clinical research in patients with inadequately controlled type 2 diabetes shows that common sage extract does not lower fasting blood glucose levels.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, sage might increase or decrease the effects of antihypertensive drugs.
Animal research suggests that common sage (Salvia officinalis) can cause prolonged blood pressure reduction. However, clinical research suggests that Spanish sage (Salvia lavandulaefolia) can increase blood pressure in some people with hypertension. Until more is known, use with caution.

Likelihood Possible Evidence D
Benzodiazepines

Theoretically, taking sage might increase the sedative and adverse effects of benzodiazepines.
In vitro evidence suggests that certain components of common sage (Salvia officinalis) can bind to benzodiazepine receptors. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cholinergic Drugs

Theoretically, sage might have additive effects when used with cholinergic drugs.
In vitro evidence suggests that common sage (Salvia officinalis) and Spanish sage (Salvia lavandulaefolia) can inhibit acetylcholinesterase and might increase acetylcholine levels.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, taking sage might increase the sedative and adverse effects of CNS depressants.
Some constituents of sage have CNS depressant activity.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP2C19.
In vitro evidence suggests that aqueous extracts of sage can inhibit CYP2C19. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP2C9.
In vitro evidence suggests that aqueous extracts of sage can inhibit CYP2C9. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP2D6.
In vitro evidence suggests that aqueous extracts of sage can inhibit CYP2D6. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Theoretically, sage might decrease the levels and clinical effects of drugs metabolized by CYP2E1.
Animal research suggests that drinking common sage (Salvia officinalis) tea increases the expression of CYP2E1. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP3A4.
In vitro evidence suggests that aqueous extracts of sage can inhibit CYP3A4. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Estrogens

Theoretically, sage might interfere with hormone therapy.
In vitro evidence suggests that geraniol, a constituent of Spanish sage (Salvia lavandulaefolia), exerts estrogenic activity. The clinical significance of this effect is unclear.

Likelihood Possible Evidence D
P-Glycoprotein Substrates

Theoretically, sage might increase levels of drugs transported by P-glycoprotein.
In vitro research suggests that common sage (Salvia officinalis) can inhibit the multi-drug transporter protein, P-glycoprotein. This effect has not been reported in humans.

Likelihood Possible Evidence D
Sage Leaf Extract, Freeze-Dried full monograph & interactions

Peppermint aerial parts essential oil5 drug types · 796 drugs

Cyclosporine (Neoral, Sandimmune)

Theoretically, peppermint oil might increase the levels and adverse effects of cyclosporine.
In animal research, peppermint oil inhibits cyclosporine metabolism and increases cyclosporine levels. Inhibition of cytochrome P450 3A4 (CYP3A4) may be partially responsible for this interaction. An interaction between peppermint oil and cyclosporine has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, peppermint might increase the levels of CYP2C19 substrates.
In vitro research shows that peppermint oil inhibits CYP2C19. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, peppermint might increase the levels of CYP2C9 substrates.
In vitro research shows that peppermint oil inhibits CYP2C9. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Clinical research in healthy volunteers shows that a single dose of peppermint oil 600 mg inhibits CYP3A4 enzymes and increases the AUC of felodipine, a CYP3A4 substrate. However, in vitro research suggests that peppermint oil only inhibits CYP3A4 at very high concentrations.

Likelihood Possible Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, peppermint might increase the levels of CYP1A2 substrates.
In vitro and animal research shows that peppermint oil and peppermint leaf inhibit CYP1A2. However, in clinical research, peppermint tea did not significantly affect the metabolism of caffeine, a CYP1A2 substrate. It is possible that the 6-day duration of treatment may have been too short to identify a difference.

Likelihood Possible Evidence B
Peppermint aerial parts essential oil full monograph & interactions

organic Aloe vera leaf gel dried extract7 drug types · 461 drugs

Digoxin (Lanoxin)

Theoretically, aloe latex might increase the risk of adverse effects when taken with cardiac glycosides.
Overuse of aloe latex can increase the risk of adverse effects from cardiac glycoside drugs, such as digoxin, due to potassium depletion. Overuse of aloe, along with cardiac glycoside drugs, can increase the risk of toxicity.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aloe gel can inhibit platelet aggregation. This inhibition was greater than that seen with celecoxib, but less than that seen with aspirin.

Likelihood Possible Evidence D
Antidiabetes Drugs

Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Preliminary clinical research suggests aloe gel might lower blood glucose levels and have additive effects when used with antidiabetes drugs. Monitor blood glucose levels closely.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Overuse of aloe latex might compound diuretic-induced potassium loss, increasing the risk of hypokalemia.

Likelihood Possible Evidence D
Stimulant Laxatives

Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Due to cathartic laxative effects of aloe latex, concomitant use with other stimulant laxatives might compound fluid and electrolyte loss.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, aloe latex might increase the risk of bleeding when taken with warfarin.
Aloe latex has stimulant laxative effects. In some people aloe latex can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. Advise patients who take warfarin not to take excessive amounts of aloe vera.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that aloe extract induces CYP1A2 enzymes.

Likelihood Possible Evidence D
organic Aloe vera leaf gel dried extract full monograph & interactions

Cinnamon bark essential oil2 drug types · 258 drugs

Antidiabetes Drugs

Theoretically, Ceylon cinnamon may have additive effects with antidiabetes drugs.
Ceylon cinnamon may lower blood glucose levels. Dose adjustments might be necessary.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, Ceylon cinnamon might have additive effects with antihypertensive drugs and increase the risk of hypotension.
Animal research shows that Ceylon cinnamon extract has vasorelaxant properties and reduces blood pressure in rat models of hypertension, possibly via inhibition of calcium influx through L-type voltage-sensitive channels.

Likelihood Possible Evidence D
Cinnamon bark essential oil full monograph & interactions

Myrrh resin extract2 drug types · 88 drugs

Antidiabetes Drugs

Theoretically, myrrh might increase the risk of hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research suggests that myrrh has hypoglycemic effects.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, myrrh might decrease the effectiveness of warfarin.
In one case, a patient who was previously stable on warfarin had a significant decline in international normalized ratio (INR) following consumption of an aqueous extract of myrrh.

Likelihood Possible Evidence D
Myrrh resin extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Sage & Aloe Throat Spray, from the product label.

Gaia Herbs

See all Gaia Herbs products
Name
Aboca S.p.A.
Pharmacist Counseling Corner

Sage & Aloe Throat Spray by Gaia Herbs: Common Questions

Does Sage & Aloe Throat Spray by Gaia Herbs interact with any medications?
Yes. Based on its ingredients, Sage & Aloe Throat Spray has a known interaction with 1,384 medications, including 1 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Sage & Aloe Throat Spray contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I use this throat spray while I'm pregnant?
Aloe and myrrh carry safety warnings against pregnancy — myrrh is rated likely unsafe because it traditionally stimulates the uterus, and aloe is rated possibly unsafe with similar concerns. Peppermint is rated likely safe in pregnancy, and cinnamon and sage have mixed or limited data. Because this is a blend, you should talk with your own doctor or pharmacist before using it during pregnancy to weigh the risks for your situation.
Can I use this while breastfeeding?
Peppermint is rated likely safe during lactation. Myrrh has no lactation data on file. Aloe is rated possibly unsafe while breastfeeding due to limited safety data and its laxative effects. Cinnamon is rated likely safe, and sage is rated possibly unsafe — traditionally said to reduce milk supply. Talk with your own doctor or pharmacist before using this spray while nursing.
Does peppermint in this spray actually work for a sore throat?
Our data covers peppermint's effectiveness for indigestion, nausea, and IBS — not specifically for sore throat. The spray is formulated with soothing ingredients like aloe and myrrh that may help topically, but we don't hold evidence for the product itself.
What are the most common side effects if I take this orally?
If swallowed, peppermint may cause abdominal pain, heartburn, nausea, or diarrhea. Myrrh may cause diarrhea in larger amounts. Aloe latex can cause cramping and diarrhea. Cinnamon and sage may cause nausea or abdominal discomfort. This spray is designed for mouth and throat use — swallowing it in large quantities is not recommended.
Is aloe safe to use in this throat spray?
Aloe gel applied topically is generally well tolerated and may have soothing properties. However, if the spray is swallowed, aloe latex carries more serious risks, including diarrhea and potassium depletion with overuse. For a throat spray used briefly in the mouth, topical aloe gel is the safer form — but check the label to confirm what form is included and use it as directed.
Will this spray interact with my blood pressure or blood sugar medications?
Yes — cinnamon and sage both carry Moderate-severity interactions with blood pressure drugs, and myrrh, aloe, and cinnamon all interact with diabetes medications. Before using this spray, check with your own doctor or pharmacist about your specific medications, as interactions can change how well they work or lower your blood sugar or blood pressure unexpectedly.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sage & Aloe Throat Spray label
Go deeper

The Full Monographs Behind Sage & Aloe Throat Spray’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Peppermint

Interacts with 796 drugs

Peppermint is a popular herb with the best evidence supporting enteric-coated peppermint oil for easing IBS symptoms. It is generally well tolerated for most adults, but it can cause heartbu...

Read the full Peppermint monograph → Herb & supplement monograph

Myrrh

Interacts with 88 drugs

Myrrh is a fragrant gum resin from Commiphora trees that has long been used in mouthwashes, throat remedies, and skin care. Modern evidence for most of its uses is limited and comes mostly f...

Read the full Myrrh monograph → Herb & supplement monograph

Aloe

Interacts with 461 drugs

Aloe vera gel is widely used on the skin for minor burns and irritation, and some research suggests it may help. Aloe latex (the yellow part) is a strong laxative that can cause cramping and...

Read the full Aloe monograph → Herb & supplement monograph

Ceylon Cinnamon

Interacts with 258 drugs

Ceylon cinnamon is the so-called 'true' cinnamon, valued as a spice and used in traditional medicine for blood sugar, cholesterol, and digestion. Evidence for most health benefits is limited...

Read the full Ceylon Cinnamon monograph → Herb & supplement monograph

Sage

Interacts with 1,296 drugs

Sage is a common kitchen herb that is generally safe in food amounts and is traditionally used for sore throats, digestion, sweating, and memory. Some early research is encouraging for sore...

Read the full Sage monograph →
Sources

Sources & How We Checked

Sage & Aloe Throat Spray's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 139 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Peppermint 41 references
  1. Liu JH, Chen GH, Yeh HZ, et al. Enteric-coated peppermint-oil capsules in the treatment of irritable bowel syndrome: a prospective, randomized trial. J Gastroenterol 1997;32:765-8. PubMed
  2. Pittler MH, Ernst E. Peppermint oil for irritable bowel syndrome: a critical review and metaanalysis. Am J Gastroenterol 1998;93:1131-5. PubMed
  3. Kline RM, Kline JJ, Di Palma J, Barbero GJ. Enteric-coated, pH-dependent peppermint oil capsules for the treatment of irritable bowel syndrome in children. J Pediatr 2001;138:125-8. PubMed
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Myrrh 8 references
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  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
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Aloe 41 references
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See these in context on the Aloe monograph →

Ceylon Cinnamon 22 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
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See these in context on the Ceylon Cinnamon monograph →

Sage 27 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
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See these in context on the Sage monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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