SAM-e By DC Overview & Drug Interactions
Check For Interactions With SAM-e
Supplement: SAM-e by DC
This product contains
Below is a list of the 'active' ingredients listed on the supplement label for this product.
For a list of 'other ingredients', such as fillers, please see the 'Label Information' section on this page.
S-Adenosylmethionine
S-adenosyl-l-methionine (SAM-e or SAMe) is a compound that is found naturally in the body and is involved in various processes, including the synthesis of neurotransmitters and the metabolism of hormones. SAM-e has been studied as a potential treatment for a variety of health conditions, including depression, osteoarthritis, and liver disease. As a dietary supplement, it is most often used for improving symptoms of depression and for osteoarthritis. In regard to depression, research suggests that SAM-e may be more effective than placebo in reducing the severity of depression and may be as effective as certain antidepressants for some individuals. However, more research is needed. Similarly, for osteoarthritis, some studies show that it is as effective in reducing symptoms for some individuals as NSAIDs (e.g., ibuprofen). There are a variety of different forms of SAM-e supplements available on the market, typically different salt forms (e.g., sulfate, sulfate-p-toluenesulfonate, and butanedisulfonate), which may affect how well it is absorbed.
See More Information Regarding SameIngredient Group | SAMe |
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Category | non-nutrient/non-botanical |
Drugs that interact with SAM-e by DC
Below is a list of drug interactions for each ingredient in this supplement product. Please note that a supplement product may contain more than one ingredient that has interactions.
Label Information
Supplement Facts:
Daily Value (DV) Target Group(s): | Adults and children 4 or more years of age |
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Minimum serving Sizes: |
2 Tablet(s)
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Maximum serving Sizes: |
2 Tablet(s)
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Servings per container | 15 |
Ingredient | Amount per Serving | Group | % DV, Adults & children 4+ years |
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S-Adenosylmethionine |
400 mg
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SAMe |
--
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Other Ingredients: |
Cellulose
Mannitol
Glyceryl Behenate
Vegetable Magnesium Stearate
Silicon Dioxide
Sodium Starch Glycolate
Enteric Coating
Forms
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Label Statments:
Formula |
- All living things contain SAM-e (S-adenosylmethionine). The body makes SAM-e from the amino acid methionine. However, you may not be able to obtain sufficient methionine levels simply by ingesting food. In addition, because of age of other factors, levels of SAM-e can fluctuate or decline. Supplementation with SAM-e is the easiest way to increase intake. SAM-e is involved in over 35 biochemical reactions involving enzymatic transmethylation. The methylation process is the mechanism by which the body rids itself of potentially damaging compounds, synthesizes neurotransmitters, makes components of cartilage, regulates enzyme activity within the cell and maintains the flexibility of cell membranes. Science has been looking into this remarkable supplement nd time after time clinical studies have drawn the same conclusions, SAM-e: Promotes healthy joint function and comfort - Boosts mood and emotional well-being. SAM-e is a revolutionary supplement. Because of its popularity and use, it has received widespread exposure in the press. Information has appeared in newspapers, magazine, on the internet, or simply through word of mouth. Whether you're a first time SAM-e user, or have been a fan for years, you probably have some questions. Please see enclosed insert for more information. A note about our enteric coating: SAM-e is enterically coated sot hat you receive optimal absorption. The enteric coating ensures that the breakdown of SAM-e occurs in the small intestine. Clinical trials indicate that absorption is more efficient in the small intestine rather than in the stomach. In addition, the enteric coating is designed to protect SAM-e from moisture. The lack of an enteric coating should not be harmful to the stomach, and there have been no reported cases tot his effect. However, the enteric coating serves as a protective barrier so that SAM-e can be absorbed where it can provide you with the greatest benefits.
- S-adenosylmethionine 200 mg
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Precautions |
- Caution: You should consult your physician before using SAM-e if you are taking MAO Inhibitors. Individuals affected by bipolar (manic) depression should not take this product.
- Like all supplements, SAM-e is not intended for use by children and you should consult your physician before using SAM-e if you are pregnant or nursing.
- Like all supplements, SAM-e is not intended for use by children and you should consult your physician before using SAM-e if you are pregnant or nursing.
- Discontinue use and consult your physician if gastrointestinal discomfort occurs.
- Tamper Evident: Do not use if imprinted foil seal under cap is broken or missing.
- Keep out of reach of children.
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Formulation |
- Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.
- Gluten free
- Promotes healthy joint function and comfort
Boosts mood and emotional well-being
Supports healthy liver function
- SAM-e was discovered in Italy in 1952 and has been one of Europe's best kept secrets for years. Through extensive testing, SAM-e has been shown to be well tolerated by most. But, perhaps the best news is that SAM-e has been found to be a safe nontoxic supplement for nearly everyone in levels of up to 1,600 mg per day.
- Mfg. in an FDA Registered Facility using Good Manufacturing Practices (GMPs)
- Suitable for vegetarians/vegans.
- Contains no wheat, soy, dairy, egg, fish/shellfish, peanuts/tree nuts.
- Made in USA
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FDA Disclaimer Statement |
- These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
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Seals/Symbols |
- Quali Pure
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FDA Statement of Identity |
- Dietary Supplement
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Suggested/Recommended/Usage/Directions |
- Directions: For adults, we recommend taking two (2) tablets daily, preferably on an empty stomach. In order to obtain maximum benefits, SAM-e should be taken at least 30 minutes prior to a meal.
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Storage |
- Keep tightly closed.
Store at room temperature: 59 degrees - 86 degrees F (15 degrees to 30 degrees C).
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Brand Information
See all products by this brand
Distributed by | |
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Name | Dee Cee Laboratories, Inc. |
Street Address | 304 Dee Cee Rd. |
City | White House |
State | TN |
ZipCode | 37188 |
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Parts of this content are provided by the Therapeutic Research Center, LLC and the Dietary Supplement Label Database.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.