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Dietary supplement

Sambucus Berry Flavored Ingredients & Drug Interactions

by Integrative Therapeutics

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Sambucus Berry Flavored is a dietary supplement by Integrative Therapeutics with 1 active ingredient. Its ingredients are commonly taken for colds, flu (influenza), other respiratory infections.Based on those ingredients, 121 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Black Elder Berry Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Sambucus Berry Flavored by Integrative Therapeutics

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Black Elder Berry Extract” is listed as a grouped ingredient — the label gives one combined amount (50 mg) without saying how much of each component you get.

This product contains one active ingredient: elderberry, a fruit extract that's been used traditionally to support various aspects of health. The liquid form includes inactive ingredients like fructose, purified water, glycerin, natural flavors, malic acid, and potassium sorbate — these are fillers and preservatives that help the product stay stable and taste good.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Elderberry product and its label doesn't state a use — see Elderberry's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for elderberry isn't strong enough to establish that it works for the conditions studied so far. The data we hold shows insufficient reliable evidence for allergic rhinitis (hay fever), cardiovascular disease, chronic fatigue syndrome, COPD, cognitive function, and lower respiratory tract infections.

That doesn't mean it doesn't work — it means the research hasn't built a solid case yet.

The evidence, ingredient by ingredient Elderberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Properly prepared elderberry products from ripe fruit are generally well tolerated. The main risk comes from raw or unripe berries, leaves, bark, and seeds, which contain a compound that breaks down into something toxic and can cause nausea, vomiting, diarrhea, weakness, dizziness, and other effects — but cooking eliminates this toxin, and this product is a prepared extract, so that's not a concern here.

One rare case report linked long-term elderberry use to autoimmune hepatitis (liver inflammation), so anyone with an underlying autoimmune condition should discuss it with their doctor first. There isn't enough reliable safety information to recommend elderberry during pregnancy or breastfeeding, so talk with your doctor or pharmacist if you're pregnant, planning to become pregnant, or nursing before starting this supplement.

Side effects, ingredient by ingredient Elderberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Elderberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 121 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before starting this supplement, have your doctor or pharmacist review your medications if you take pazopanib (Votrient) or any immunosuppressant drugs. These are the two drug categories with documented moderate interactions with elderberry.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Elderberry may be worth considering if you're interested in traditional immune support, but the evidence for specific conditions hasn't been proven yet. If you take pazopanib, immunosuppressant drugs, or have an underlying autoimmune disease, talk with your doctor or pharmacist before adding this product — and check your exact medications with the tool on this page.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sambucus Berry Flavored, straight from the product label.

Brand Integrative Therapeutics
Barcode (UPC) 871791004498
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Feb 22, 2024
DSLD ID 305293
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sambucus Berry Flavored by Integrative Therapeutics, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 mL, 10 mL
Maximum serving Sizes:
5 mL, 10 mL
Servings per container
12
UPC/BARCODE
871791004498
IngredientAmount% DV
Calories15 Calorie(s), 30 Calorie(s)--
Total Carbohydrates4 Gram(s), 7 Gram(s)1%, 3%
Added Sugars3 Gram(s), 6 Gram(s)6%, 12%
Total Sugars3 Gram(s), 6 Gram(s)--
Elderberry3200 mg--
Black Elder Berry Extract50 mg, 100 mg--

Other ingredients: Fructose, Water, Purified, Glycerin, Natural Flavors, Malic Acid, Potassium Sorbate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommendation: Adults: Take 2 teaspoons (tsp) (10 mL) daily. Intensive use: Take 2 teaspoons (10 mL) four times daily. Children ages 7 and older: Take 1 teaspoon (5 mL) daily. Intensive use: Take 1 teaspoon (5 mL) three times daily. Not formulated for children under 7 years of age. Shake well before each use.

Precautions

Not formulated for children under 7 years of age. Keep out of reach of children.

Safety sealed with inner seal. Do not use if seal is broken or missing.

If you are pregnant, nursing, or taking any medications, consult a healthcare professional before use.

Storage

Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.

Formulation

Contains no wheat, gluten, dairy, or artificial colors.

Vegan

Brand IP Statement(s)

Copyright 2023 Integrative Therapeutics, LLC.

Seals/Symbols

Quality Global Sourcing Bottled & Tested in the USA

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

Elderberry Syrup

FDA Statement of Identity

Dietary Supplement

General Statements

For more information, please visit integrativepro.com Servings per container 1 teaspoon (5 mL) 24 2 teaspoons (10 mL) 12

See for yourself

Sambucus Berry Flavored by Integrative Therapeutics label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Sambucus Berry Flavored by Integrative Therapeutics

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size5 mL Dosage formLiquid Servings per container12 Amounts shown are per serving.

Black Elder Berry Extract

Interacts with
121 drugs
50 mg per serving Form: Anthocyanins

Elderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu sym...

Black Elder Berry Extract monograph & interactions

Other (inactive) ingredients: Fructose, Water, Purified, Glycerin, Natural Flavors, Malic Acid, Potassium Sorbate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Sambucus Berry Flavored by Integrative Therapeutics Drug Interactions

Want to check YOUR meds against Sambucus Berry Flavored?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
121Drugs
121 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Sambucus Berry Flavored with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Black Elder Berry Extract2 drug types · 121 drugs

Immunosuppressants

Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Elderberry has immunostimulant activity, increasing the production of cytokines, including interleukin and tumor necrosis factor.

Likelihood Possible Evidence B
Pazopanib (Votrient)

Theoretically, elderberry might interact with pazopanib, potentially increasing the risk of adverse effects.
In one case, a 65-year-old patient taking pazopanib for 4 weeks for soft-tissue sarcoma developed severe nausea, loose stools, and elevated alanine transaminase and aspartate transaminase levels and was diagnosed with grade 3 liver injury. The patient reported taking elderberry supplements for 2 years, dose unspecified, and was also taking a multivitamin and a calcium supplement. The patient's symptoms and liver enzyme levels improved upon discontinuation of pazopanib and all supplements. Pazopanib treatment was re-initiated, at a lower dose, with no further evidence of liver injury. It was unclear in this case report if the elderberry supplements were derived from the berry, the flower, or the combination.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Sambucus Berry Flavored, from the product label.

Integrative Therapeutics

See all Integrative Therapeutics products
Name
Integrative Therapeutics, LLC
City
Green Bay
State
WI
ZipCode
54311
Phone Number
800.931.1709
Web Address
integrativepro.com
Pharmacist Counseling Corner

Sambucus Berry Flavored by Integrative Therapeutics: Common Questions

Does Sambucus Berry Flavored by Integrative Therapeutics interact with any medications?
Yes. Based on its ingredients, Sambucus Berry Flavored has a known interaction with 121 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Sambucus Berry Flavored contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to use during pregnancy or while breastfeeding?
There isn't enough reliable safety information about elderberry during pregnancy or breastfeeding. The safety data advises against it during both periods. Talk with your doctor or pharmacist about whether it's right for you if you're pregnant, planning to become pregnant, or nursing.
What's in this product besides the elderberry?
The liquid contains fructose, purified water, glycerin, natural flavors, malic acid, and potassium sorbate — these are inactive ingredients that give it sweetness, texture, flavor, and shelf stability.
Does elderberry actually work for colds or the flu?
We don't have strong evidence in our data to confirm that. The research on lower respiratory tract infections, allergies, and other conditions shows insufficient reliable evidence — meaning the science hasn't yet proven it works for those purposes.
Can I get sick from raw elderberries?
Yes — raw or unripe elderberries, seeds, leaves, and bark contain a toxin that can cause nausea, vomiting, diarrhea, weakness, dizziness, and other effects. This product is a prepared extract from ripe fruit, so that's not a risk here. Cooking also eliminates the toxin.
What's Black Elder Berry Extract in the ingredients list?
Black Elder Berry Extract is elderberry — it's the same active ingredient listed under a different name, so this product contains one active ingredient, not two.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Sambucus Berry Flavored is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sambucus Berry Flavored label
Go deeper

The Full Monographs Behind Sambucus Berry Flavored’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Sambucus Berry Flavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Elderberry 6 references
  1. Barak V, Halperin T, Kalickman I. The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. Eur Cytokine Netw 2001;12:290-6..
  2. Elderberry (Sambucus species). The Poison Plant Patch, Novia Scotia Museum, 2007. Available at: http://museum.gov.ns.ca/poison/?section=species&id=117 (Accessed 16 October 2009).
  3. European elder. Canadian Poisonous Plants Information System. Available at: http://www.cbif.gc.ca/pls/pp/ppack.jump?p_null=all&p_psn=121&p_type=all&p_sci=comm&p_x=px (Accessed 16 October 2009).
  4. Raus K, Pleschka S, Klein P, Schoop R, Fisher P. Effect of an echinacea-based hot drink versus oseltamivir in Influenza treatment: a randomized, double-blind, double-dummy, multicenter, noninferiority clinical trial. . Curr Ther Res Clin Exp. 2015;20;77:6 PubMed
  5. Ramachandran A, Antala D, Pudasainee P, Panginikkod S, Gupta H. A Plausible Association Between the Use of Elderberry and Autoimmune Hepatitis. Cureus 2022;14(4):e24250. PubMed
  6. Agarwal N, Mangla A. Elderberry interaction with pazopanib in a patient with soft-tissue sarcoma: A case report and literature review. Mol Clin Oncol 2024;20(5):36. PubMed

See these in context on the Elderberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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