SAMe 200 mg By Jarrow Formulas Overview & Drug Interactions
Check For Interactions With SAMe 200 mg
Supplement: SAMe 200 mg by Jarrow Formulas
SAMe 200 mg Label Images
This product contains
Below is a list of the 'active' ingredients listed on the supplement label for this product.
For a list of 'other ingredients', such as fillers, please see the 'Label Information' section on this page.
S-Adenosyl Methionine
S-adenosyl-l-methionine (SAM-e or SAMe) is a compound that is found naturally in the body and is involved in various processes, including the synthesis of neurotransmitters and the metabolism of hormones. SAM-e has been studied as a potential treatment for a variety of health conditions, including depression, osteoarthritis, and liver disease. As a dietary supplement, it is most often used for improving symptoms of depression and for osteoarthritis. In regard to depression, research suggests that SAM-e may be more effective than placebo in reducing the severity of depression and may be as effective as certain antidepressants for some individuals. However, more research is needed. Similarly, for osteoarthritis, some studies show that it is as effective in reducing symptoms for some individuals as NSAIDs (e.g., ibuprofen). There are a variety of different forms of SAM-e supplements available on the market, typically different salt forms (e.g., sulfate, sulfate-p-toluenesulfonate, and butanedisulfonate), which may affect how well it is absorbed.
See More Information Regarding Same| Ingredient Group | SAMe |
|---|---|
| Category | non-nutrient/non-botanical |
- SAM-e Tosylate Disulfate
Drugs that interact with SAMe 200 mg by Jarrow Formulas
Below is a list of drug interactions for each ingredient in this supplement product. Please note that a supplement product may contain more than one ingredient that has interactions.
Label Information
Supplement Facts:
| Daily Value (DV) Target Group(s): | Adults and children 4 or more years of age |
|---|---|
| Minimum serving Sizes: |
1 Tablet(s)
|
| Maximum serving Sizes: |
1 Tablet(s)
|
| Servings per container | 60 |
| UPC/BARCODE | 790011200161 |
| Ingredient | Amount per Serving | Group | % DV, Adults & children 4+ years |
|---|---|---|---|
| S-Adenosyl Methionine |
200 mg
|
SAMe |
--
|
| Other Ingredients: |
Cellulose
Mannitol
Glyceryl Behenate
Magnesium Stearate
Silicon Dioxide
Sodium Starch Glycolate
Enteric Coating
Forms
|
|---|
Label Statments:
| Formulation |
- Full potency
- pH-sensitive - food grade enteroguard coating
- Promotes:
Joint strength
Liver detoxification
Mood and brain function
- Enteric-coated tablets
- V Vegan
- Suitable for vegetarians/vegans.
- No wheat, gluten, soybeans, dairy, egg, fish/shellfish, or peanuts/tree nuts.
- EnteroGuard is a proprietary cellulose-based, food-grade, pH-sensitive enteric coating that resists stomach acid and disintegrates in the less acidic pH of the upper intestines, where the SAMe is made available for absorption.
- SAMe has been clinically shown to have the following benefits:
Joint Strength
SAMe supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue known as glycosaminoglycans (GAGs), including glucosamine and chondroitin, are sulfated by SAMe metabolites to yield sulfated GAGs, such as glucosamine sulfate and chondroitin sulfate.
Brain Metabolism
SAMe methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin).
Liver
SAMe metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase, glutathione reductase and glutathione-S-transferase), which are components of the body’s endogenous antioxidant network and important for liver function, including phase II detoxification.
|
|---|---|
| Suggested/Recommended/Usage/Directions |
- Usage: Take 1 tablet 1 or 2 times per day on an empty stomach or as directed by your qualified healthcare professional.
- For best results, use with Jarrow Formulas JarroSil, the biologically Activated Silicon.
|
| Precautions |
- Warning: Individuals using prescribed medications such as antidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRIs) and MAO Inhibitors should consult a physician before using this product.
- Individuals with Parkinson’s disease, bi-polar disorder or manic depression should not use SAMe.
- Do not use if pregnant or nursing.
- Do not exceed recommended intake. May cause gastrointestinal upset in some persons. If you experience discomfort, discontinue use.
- Keep out of the reach of children.
|
| General Statements |
- Jarrow Formulas SAMe 200 is foil blister-packed to maximize stability and safety. Do not use if outer seal of blister pack is broken.
|
| Formula |
- Full potency 200 mg SAMe (net yield) is derived from 400 mg of SAMe tosylate disulfate.
- S-Adenosyl Methionine
200 mg (net yield) SAMe from 400 mg SAMe tosylate disulfate
Highest concentration of Active S,S Form
- Jarrow Formulas SAMe 200 provides a full 200 mg SAMe (net yield) from 400 mg of SAMe tosylate disulfate. SAMe 200 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.
Contains more of the active S,S form
Found in all living cells, SAMe is a metabolite of methionine (an essential amino acid). SAMe is a chiral molecule consisting of two forms: (S,S) SAMe and (R,S) SAMe. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas SAMe is made naturally by microbiological fermentation and then specially processed without chemical solvents to preserve 68-80% (S,S) SAMe, the highest active level available.
|
| Storage |
- Store in a cool, dry place.
|
| FDA Statement of Identity |
- Dietary Supplement
|
| Brand IP Statement(s) |
- 2020 Jarrow Formulas
|
| FDA Disclaimer Statement |
- These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
|
Brand Information
See all products by this brand
| Distributed exclusively by | |
|---|---|
| Name | Jarrow Formulas Superior Nutrition and Formulation |
| City | Los Angeles |
| State | CA |
| ZipCode | 90035-4317 |
| Phone Number | (866) 459-4154 |
| Web Address | www.jarrow.com |
Return to the main supplement interaction checker page
Parts of this content are provided by the Therapeutic Research Center, LLC and the Dietary Supplement Label Database.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.