Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Saw Palmetto 160 mg Ingredients & Drug Interactions

by Exchange Select

Saw Palmetto 160 mg label
See full label image
Softgel Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Saw Palmetto 160 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Saw Palmetto 160 mg is a dietary supplement by Exchange Select with 1 active ingredient. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, urinary problems, hair loss.Based on those ingredients, 174 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Saw Palmetto extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Saw Palmetto 160 mg by Exchange Select

Ask about any prescription or over-the-counter medication and we check it for interactions with Saw Palmetto 160 mg by Exchange Select — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Saw Palmetto 160 mg by Exchange Select

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: saw palmetto extract at 160 mg per softgel capsule. Saw palmetto is a plant extract traditionally used for urinary and prostate health.

The inactive ingredients are olive oil, gelatin, glycerin, purified water, and caramel powder—standard softgel capsule components.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: supports a healthy prostate.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Non-neurogenic lower urinary tract symptoms (LUTS), Chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS), Prostatitis, Prostate function, Urinary flow.
  • The closest evidence on file: Saw Palmetto is rated "Possibly Ineffective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).
  • Also on file: Saw Palmetto is rated "Insufficient Reliable Evidence To Rate" for Chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS), Prostatitis, Non-neurogenic lower urinary tract symptoms (LUTS).

The evidence for saw palmetto is mixed. For benign prostatic hyperplasia (BPH)—the enlarged prostate condition many men take it for—the data rates it as possibly ineffective.

For recovery after transurethral resection of the prostate (TURP), a surgical procedure, it's rated possibly effective. For other uses like hair loss, chronic bronchitis, and lower urinary tract symptoms, we don't have enough reliable evidence to say whether it works or not.

The evidence, ingredient by ingredient Saw Palmetto

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Saw palmetto is generally well tolerated in adults, and most side effects reported are mild and reversible. The most common ones are abdominal pain, constipation, decreased libido, diarrhea, dizziness, fatigue, headache, nausea, rhinitis, and vomiting.

A few rare cases of heart-related symptoms and skin reactions like drug eruptions have been reported, though they're uncommon. The safety data advises against use during pregnancy or while breastfeeding because of possible hormone effects and lack of safety information.

Side effects, ingredient by ingredient Saw Palmetto

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Saw Palmetto.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 174 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you're on blood thinners (anticoagulants) or antiplatelet drugs like aspirin or clopidogrel—saw palmetto may increase bleeding risk (Moderate severity). Also double-check if you take estrogens or birth control pills; saw palmetto might reduce how well they work (Moderate severity).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Saw palmetto may be worth considering if you're dealing with certain prostate issues, but the evidence isn't strong for BPH. The main caution is the bleeding risk if you're on blood thinners, and concerns about it interfering with birth control or hormone therapy.

If you take any medications—especially anticoagulants, contraceptives, or estrogens—talk with your doctor or pharmacist before adding this.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Saw Palmetto 160 mg, straight from the product label.

Brand Exchange Select
Barcode (UPC) 614299513105
Net contents 120 Softgel(s)
Market status On market
Date entered into DSLD Aug 22, 2017
DSLD ID 76740
Product type Botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult Male (18-50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Saw Palmetto 160 mg by Exchange Select, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
UPC/BARCODE
614299513105
IngredientAmount% DV
Saw Palmetto extract160 mg--

Other ingredients: Saw Palmetto extract, Olive Oil, Gelatin, Glycerin, purified Water, Caramel powder

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Safety sealed. Do not use if printed seal under cap is cut, torn, or missing.

Keep out of the reach of children.

Warning: Men taking medication(s) or who have a health condition should consult their physician before using this product.

Caution: Not for use by women.

General Statements

Targeted health

Quality value

Herbs have a distinct natural odor and may vary in color.

European men have supplemented their diets with saw palmetto for many years.

"Satisfaction guaranteed or your money back."

Formula

~ Supports a healthy prostate

Clinical research indicates that regular use of saw palmetto provides phytonutrients that may help maintain a healthy prostate.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Men - Take one softgel two times daily with food as a dietary supplement.

Storage

Store at 15(0)-30(0) C (59(0)-86(0) F).

Formulation

No artificial colors or flavors No gluten ~ No lactose ~ No trans fat

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General

136861 500253 USA646823

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Saw Palmetto 160 mg by Exchange Select label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Saw Palmetto 160 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Saw Palmetto 160 mg by Exchange Select

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Saw Palmetto extract

Interacts with
174 drugs
160 mg per serving Form: Active Sterols, Fatty Acids

Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no bett...

Saw Palmetto extract monograph & interactions

Other (inactive) ingredients: Saw Palmetto extract, Olive Oil, Gelatin, Glycerin, Purified Water, Caramel powder. These complete the product’s ingredient list but are not active constituents.

Interaction report

Saw Palmetto 160 mg by Exchange Select Drug Interactions

Want to check YOUR meds against Saw Palmetto 160 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
174Drugs
174 Moderate

Ingredients driving the most interactions

Saw Palmetto extract 174

Individual Drug Interactions

The ingredients in Saw Palmetto 160 mg interact with 174 drugs. Click any drug to see the details.

1 of the 1 ingredient in Saw Palmetto 160 mg interact with drugs. Each result below shows which ingredient is responsible. Saw Palmetto extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Saw Palmetto 160 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Saw Palmetto extract3 drug types · 174 drugs

Anticoagulant/Antiplatelet Drugs

Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Saw palmetto is reported to prolong bleeding time. Theoretically, it might increase the risk of bleeding when used concomitantly with anticoagulant or antiplatelet drugs.

Likelihood Possible Evidence D
Contraceptive Drugs

Saw palmetto might reduce the effectiveness of contraceptive drugs.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with contraceptive drugs taken concomitantly.

Likelihood Possible Evidence B
Estrogens

Saw palmetto might reduce the effectiveness of estrogens.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with estrogens taken concomitantly.

Likelihood Possible Evidence B
Saw Palmetto extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Saw Palmetto 160 mg, from the product label.

Exchange Select

See all Exchange Select products
Name
International Vitamin Corporation
City
Freehold
State
NJ
ZipCode
07728
Phone Number
1-866-927-5470
Pharmacist Counseling Corner

Saw Palmetto 160 mg by Exchange Select: Common Questions

Does Saw Palmetto 160 mg by Exchange Select interact with any medications?
Yes. Based on its ingredients, Saw Palmetto 160 mg has a known interaction with 174 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Saw Palmetto 160 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on birth control?
You should check with your doctor or pharmacist first. Saw palmetto might have antiestrogenic effects that could theoretically interfere with how your birth control works, which means it might be less effective. This is one of the main interactions to clear before starting.
Is saw palmetto safe during pregnancy?
No. The safety data advises against use during pregnancy because of possible effects on hormones and lack of safety information. If you're pregnant or planning to become pregnant, talk with your doctor before taking this.
What are the side effects?
Most side effects are mild and reversible. The most common ones are abdominal pain, constipation, diarrhea, dizziness, fatigue, headache, nausea, and vomiting. Very rarely, skin reactions or heart-related symptoms have been reported, but these are uncommon.
Does saw palmetto actually work for prostate problems?
The evidence is limited. For benign prostatic hyperplasia (BPH)—enlarged prostate—our data rates it as possibly ineffective. For recovery after prostate surgery (TURP), it's rated possibly effective. For other uses like hair loss or lower urinary tract symptoms, we don't have enough reliable evidence yet.
Can I take this with blood thinners?
You need to check with your doctor first. Saw palmetto is reported to prolong bleeding time, so it may increase your bleeding risk if you're also on blood thinners or antiplatelet drugs like warfarin or aspirin. This is a Moderate severity interaction that needs personalized medical advice.
Is saw palmetto safe while breastfeeding?
No. The safety data advises against use while breastfeeding due to insufficient safety information. Talk with your doctor if you're breastfeeding and thinking about this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Saw Palmetto 160 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Saw Palmetto 160 mg label
Go deeper

The Full Monographs Behind Saw Palmetto 160 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Saw Palmetto

Interacts with 174 drugs

Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no better than a placebo for most men, though i...

Read the full Saw Palmetto monograph →
Sources

Sources & How We Checked

Saw Palmetto 160 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 22 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Saw Palmetto 22 references
  1. Wilt TJ, Ishani A, Stark G, et al. Saw palmetto extracts for treatment of benign prostatic hyperplasia: a systematic review. JAMA 1998;280:1604-9. PubMed
  2. Carraro JC, Raynaud JP, Koch G, et al. Comparison of phytotherapy (Permixon) with finasteride in the treatment of benign prostate hyperplasia: a randomized international study of 1,098 patients. Prostate 1996;29:231-40. DOI
  3. Di Silverio F, D'Eramo G, Lubrano C, et al. Evidence that Serenoa repens extract displays an antiestrogenic activity in prostatic tissue of benign prostatic hypertrophy patients. Eur Urol 1992;21:309-14. PubMed
  4. Stepanov VN, Siniakova LA, Sarrazin B, Raynaud JP. Efficacy and tolerability of the lipidosterolic extract of Serenoa repens (Permixon) in benign prostatic hyperplasia: a double-blind comparison of two dosage regimens. Adv Ther 1999;16:231-41.
  5. Cheema P, El-Mefty O, Jazieh AR. Intraoperative haemorrhage associated with the use of extract of Saw Palmetto herb: a case report and review of literature. J Intern Med 2001;250:167-9. PubMed
  6. Jibrin I, Erinle A, Saidi A, Aliyu ZY. Saw palmetto-induced pancreatitis. South Med J 2006;99:611-2. PubMed
  7. Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med 2002
  8. Avins AL, Bent S, Staccone S, et al. A detailed safety assessment of a saw palmetto extract. Complement Ther Med 2008;16:147-54. PubMed
  9. Morgia, G., Mucciardi, G., Gali, A., Madonia, M., Marchese, F., Di, Benedetto A., Romano, G., Bonvissuto, G., Castelli, T., Macchione, L., and Magno, C. Treatment of chronic prostatitis/chronic pelvic pain syndrome category IIIA with Serenoa repens plus
  10. Aliaev, IuG, Vinarov, A. Z., Lokshin, K. L., and Spivak, L. G. [Efficiency and safety of prostamol-Uno in patients with chronic abacterial prostatitis]. Urologiia. 2006;(1):47-50.
  11. Agbabiaka, T. B., Pittler, M. H., Wider, B., and Ernst, E. Serenoa repens (saw palmetto): a systematic review of adverse events. Drug Saf 2009;32(8):637-647. PubMed
  12. Wargo, K. A., Allman, E., and Ibrahim, F. A possible case of saw palmetto-induced pancreatitis. South.Med.J. 2010;103(7):683-685. PubMed
  13. Lapi, F., Gallo, E., Giocaliere, E., Vietri, M., Baronti, R., Pieraccini, G., Tafi, A., Menniti-Ippolito, F., Mugelli, A., Firenzuoli, F., and Vannacci, A. Acute liver damage due to Serenoa repens: a case report. Br.J.Clin.Pharmacol. 2010;69(5):558-560.
  14. Mantovani, F. Serenoa repens in benign prostatic hypertrophy: analysis of 2 Italian studies. Minerva Urol.Nefrol. 2010;62(4):335-340.
  15. Hanaka, M., Yoshii, C., Yatera, K., Ito, C., Chojin, Y., Nagata, S., Yamasaki, K., Nishida, C., Kawanami, T., Kawanami, Y., Ishimoto, H., and Mukae, H. [A case of rhabdomyolysis caused by saw palmetto of healthy foods]. J.UOEH. 6-1-2012;34(2):193-199. PubMed
  16. Miroddi, M., Carni, A., Mannucci, C., Moleti, M., Navarra, M., and Calapai, G. Hot flashes in a young girl: a wake-up call concerning Serenoa repens use in children. Pediatrics 2012;130(5):e1374-e1376.
  17. Braeckman J. The extract of Serenoa repens in the treatment of benign prostatic hyperplasia: a multicenter open study. Current Therapeutic Research 1994;55(7):776-785. DOI
  18. Jipescu D, Patel A, Bohra H, Pientka A. Rare case of saw palmetto induced heart block. JACC 2017;69(11) supplement:2310.
  19. Morabito P, Miroddi M, Giovinazzo S, Spina E, Calapai G. Serenoa repens as an endocrine disruptor in a 10-year-Old young girl: a new case report. Pharmacology. 2015;96(1-2):41-3. doi: 10.1159/000431327.
  20. Gammoudi R, Ameur K, Ouni B, et al. Fixed drug eruption to Serenoa repens: first case report and consideration of the use of herbal medicine. Dermatol Ther 2020 Aug 29:e14247.
  21. Paulis G, Paulis A, Perletti G. Serenoa repens and its effects on male sexual function. A systematic review and meta-analysis of clinical trials. Arch Ital Urol Androl 2021;93(4):475-480. PubMed
  22. Venkateswaran S, Declet-Bauzo R, Shodeinde M, Gilford P. Postoperative Retroperitoneal Hematoma: A Case of Saw Palmetto and the Importance of Primary Care Intervention. HCA Healthc J Med 2020;1(5):279-282. PubMed

See these in context on the Saw Palmetto monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team