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Dietary supplement

Saw Palmetto 320 mg Ingredients & Drug Interactions

by Groovy Bee

Saw Palmetto 320 mg label
See full label image
Softgel Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Saw Palmetto 320 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Saw Palmetto 320 mg is a dietary supplement by Groovy Bee with 1 active ingredient. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, urinary problems, hair loss.Based on those ingredients, 174 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Saw Palmetto Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Saw Palmetto 320 mg by Groovy Bee

Ask about any prescription or over-the-counter medication and we check it for interactions with Saw Palmetto 320 mg by Groovy Bee — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Saw Palmetto 320 mg by Groovy Bee

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: saw palmetto oil at 320 mg per softgel. The remaining ingredients—gelatin, glycerin, purified water, and caramel powder—are inactive excipients that form and flavor the capsule.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: prostate and urinary health and healthy hair.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Non-neurogenic lower urinary tract symptoms (LUTS), Androgenic alopecia.
  • The closest evidence on file: Saw Palmetto is rated "Possibly Ineffective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).
  • Also on file: Saw Palmetto is rated "Insufficient Reliable Evidence To Rate" for Androgenic alopecia, Non-neurogenic lower urinary tract symptoms (LUTS).

The evidence for saw palmetto is mixed and depends on what you're using it for. It's possibly effective for a specific type of prostate surgery outcome (transurethral resection of the prostate, or TURP), but it's possibly ineffective for benign prostatic hyperplasia (BPH)—the enlarged prostate condition many people take it for.

For hair loss, urinary symptoms, and chronic bronchitis, we don't have enough reliable evidence to rate whether it works.

The evidence, ingredient by ingredient Saw Palmetto

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Saw palmetto is generally well tolerated in adults, with mild and reversible side effects when they do occur. The most common ones are abdominal pain, constipation, diarrhea, dizziness, fatigue, headache, nausea, and decreased libido.

Rarely, skin reactions (fixed drug eruptions with blistering) and heart rhythm changes have been reported. You should avoid this supplement during pregnancy—the safety data is insufficient and it may affect hormones.

Also avoid it while breastfeeding due to lack of safety information.

Side effects, ingredient by ingredient Saw Palmetto

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Saw Palmetto.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 174 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, double-check with your pharmacist if you're on blood thinners or antiplatelet drugs (warfarin, aspirin, clopidogrel)—the risk of increased bleeding is Moderate. Also check if you take estrogens or birth control pills, since saw palmetto may reduce their effectiveness.

Use the search tool on this page with your full medication list.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Saw palmetto may be worth considering if you're looking at it for prostate surgery recovery, though the evidence for common uses like enlarged prostate is weak. If you take blood thinners, estrogens, or birth control, this one needs a pharmacist check first.

Pregnant or nursing? Skip it.

Talk to your pharmacist about whether this fits your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Saw Palmetto 320 mg, straight from the product label.

Brand Groovy Bee
Barcode (UPC) 050742588090
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Aug 22, 2024
DSLD ID 317760
Product type Botanical
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Saw Palmetto 320 mg by Groovy Bee, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
60
UPC/BARCODE
050742588090
IngredientAmount% DV
Saw Palmetto Oil320 mg--

Other ingredients: Gelatin, Glycerin, Water, Purified, Caramel, Powder

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Extracted from the berries of the Serenoa repens plant, Groove Bee Saw Palmetto Softgels are a rich source of fatty acids that support optimal prostate and urinary health and promote healthy hair.

Saw Palmetto (320mg each)

Formulation

It is non-GMO, gluten free and lab tested for glyphosate, heavy metals and microbiology.

Supports prostate, urinary and hair health

Glyphosate tested Laboratory verified

Certified by Natural Food Certifiers, Inc.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

Store in a cool, dry place away from direct sunlight. Fully close the bottle after each use.

General Statements

Scan to learn more!

307-213-4116

Precautions

If pregnant or under a doctor's care, consult your physician before using this product.

Do not use if the safety seal is broken.

Keep out of reach of children.

Manufactured in a facility which may contain nuts (peanuts, tree nuts).

Seals/Symbols

Non GMO NFC Certified China free

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Saw Palmetto 320 mg by Groovy Bee label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Saw Palmetto 320 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Saw Palmetto 320 mg by Groovy Bee

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.

Saw Palmetto Oil

Interacts with
174 drugs
320 mg per serving Form: Fatty Acids

Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no bett...

Saw Palmetto Oil monograph & interactions

Other (inactive) ingredients: Gelatin, Glycerin, Water, Purified, Caramel, Powder. These complete the product’s ingredient list but are not active constituents.

Interaction report

Saw Palmetto 320 mg by Groovy Bee Drug Interactions

Want to check YOUR meds against Saw Palmetto 320 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
174Drugs
174 Moderate

Ingredients driving the most interactions

Saw Palmetto Oil 174

Individual Drug Interactions

The ingredients in Saw Palmetto 320 mg interact with 174 drugs. Click any drug to see the details.

1 of the 1 ingredient in Saw Palmetto 320 mg interact with drugs. Each result below shows which ingredient is responsible. Saw Palmetto Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Saw Palmetto 320 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Saw Palmetto Oil3 drug types · 174 drugs

Anticoagulant/Antiplatelet Drugs

Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Saw palmetto is reported to prolong bleeding time. Theoretically, it might increase the risk of bleeding when used concomitantly with anticoagulant or antiplatelet drugs.

Likelihood Possible Evidence D
Contraceptive Drugs

Saw palmetto might reduce the effectiveness of contraceptive drugs.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with contraceptive drugs taken concomitantly.

Likelihood Possible Evidence B
Estrogens

Saw palmetto might reduce the effectiveness of estrogens.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with estrogens taken concomitantly.

Likelihood Possible Evidence B
Saw Palmetto Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Saw Palmetto 320 mg, from the product label.

Groovy Bee

See all Groovy Bee products
Name
Groovy Bee
Street Address
7600 Chevy Chase Drive, Suite 300
City
Austin
State
TX
ZipCode
78752
Phone Number
1-800-476-4059
Web Address
groovybee.com
Pharmacist Counseling Corner

Saw Palmetto 320 mg by Groovy Bee: Common Questions

Does Saw Palmetto 320 mg by Groovy Bee interact with any medications?
Yes. Based on its ingredients, Saw Palmetto 320 mg has a known interaction with 174 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Saw Palmetto 320 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No. Saw palmetto is rated as likely unsafe during pregnancy because of possible effects on hormones and insufficient safety data. It's also not recommended while breastfeeding. Talk to your doctor or pharmacist about alternatives if you're pregnant or nursing.
What are the side effects?
Most side effects are mild and reversible. You might experience abdominal pain, constipation, diarrhea, dizziness, fatigue, headache, nausea, or decreased libido. Rarely, skin reactions with blistering or heart rhythm issues have been reported. Stop and contact your pharmacist if anything concerns you.
Does saw palmetto actually work for an enlarged prostate?
The evidence suggests it's probably ineffective for benign prostatic hyperplasia—the common enlarged prostate condition. It is possibly effective for a specific type of prostate surgery outcome (TURP), but that's a narrower use case. Talk to your doctor about what the evidence actually supports.
Will this affect my birth control?
Possibly. Saw palmetto has antiestrogenic effects and theoretically might interfere with birth control pills and estrogen therapy. The mechanism isn't proven in human trials, but it's a Moderate-level concern. Check with your pharmacist before combining them.
Can I take this with blood thinners like warfarin or aspirin?
You need to check with your pharmacist first. Saw palmetto can prolong bleeding time and may increase the risk of bleeding when combined with blood thinners or antiplatelet drugs. This is a Moderate-level interaction and requires professional guidance.
What's inside this softgel besides the active ingredient?
The capsule contains gelatin, glycerin, purified water, and caramel powder to form and flavor it. These are inactive ingredients and don't contribute to the supplement's effects.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Saw Palmetto 320 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Saw Palmetto 320 mg label
Go deeper

The Full Monographs Behind Saw Palmetto 320 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Saw Palmetto

Interacts with 174 drugs

Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no better than a placebo for most men, though i...

Read the full Saw Palmetto monograph →
Sources

Sources & How We Checked

Saw Palmetto 320 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 22 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Saw Palmetto 22 references
  1. Wilt TJ, Ishani A, Stark G, et al. Saw palmetto extracts for treatment of benign prostatic hyperplasia: a systematic review. JAMA 1998;280:1604-9. PubMed
  2. Carraro JC, Raynaud JP, Koch G, et al. Comparison of phytotherapy (Permixon) with finasteride in the treatment of benign prostate hyperplasia: a randomized international study of 1,098 patients. Prostate 1996;29:231-40. DOI
  3. Di Silverio F, D'Eramo G, Lubrano C, et al. Evidence that Serenoa repens extract displays an antiestrogenic activity in prostatic tissue of benign prostatic hypertrophy patients. Eur Urol 1992;21:309-14. PubMed
  4. Stepanov VN, Siniakova LA, Sarrazin B, Raynaud JP. Efficacy and tolerability of the lipidosterolic extract of Serenoa repens (Permixon) in benign prostatic hyperplasia: a double-blind comparison of two dosage regimens. Adv Ther 1999;16:231-41.
  5. Cheema P, El-Mefty O, Jazieh AR. Intraoperative haemorrhage associated with the use of extract of Saw Palmetto herb: a case report and review of literature. J Intern Med 2001;250:167-9. PubMed
  6. Jibrin I, Erinle A, Saidi A, Aliyu ZY. Saw palmetto-induced pancreatitis. South Med J 2006;99:611-2. PubMed
  7. Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med 2002
  8. Avins AL, Bent S, Staccone S, et al. A detailed safety assessment of a saw palmetto extract. Complement Ther Med 2008;16:147-54. PubMed
  9. Morgia, G., Mucciardi, G., Gali, A., Madonia, M., Marchese, F., Di, Benedetto A., Romano, G., Bonvissuto, G., Castelli, T., Macchione, L., and Magno, C. Treatment of chronic prostatitis/chronic pelvic pain syndrome category IIIA with Serenoa repens plus
  10. Aliaev, IuG, Vinarov, A. Z., Lokshin, K. L., and Spivak, L. G. [Efficiency and safety of prostamol-Uno in patients with chronic abacterial prostatitis]. Urologiia. 2006;(1):47-50.
  11. Agbabiaka, T. B., Pittler, M. H., Wider, B., and Ernst, E. Serenoa repens (saw palmetto): a systematic review of adverse events. Drug Saf 2009;32(8):637-647. PubMed
  12. Wargo, K. A., Allman, E., and Ibrahim, F. A possible case of saw palmetto-induced pancreatitis. South.Med.J. 2010;103(7):683-685. PubMed
  13. Lapi, F., Gallo, E., Giocaliere, E., Vietri, M., Baronti, R., Pieraccini, G., Tafi, A., Menniti-Ippolito, F., Mugelli, A., Firenzuoli, F., and Vannacci, A. Acute liver damage due to Serenoa repens: a case report. Br.J.Clin.Pharmacol. 2010;69(5):558-560.
  14. Mantovani, F. Serenoa repens in benign prostatic hypertrophy: analysis of 2 Italian studies. Minerva Urol.Nefrol. 2010;62(4):335-340.
  15. Hanaka, M., Yoshii, C., Yatera, K., Ito, C., Chojin, Y., Nagata, S., Yamasaki, K., Nishida, C., Kawanami, T., Kawanami, Y., Ishimoto, H., and Mukae, H. [A case of rhabdomyolysis caused by saw palmetto of healthy foods]. J.UOEH. 6-1-2012;34(2):193-199. PubMed
  16. Miroddi, M., Carni, A., Mannucci, C., Moleti, M., Navarra, M., and Calapai, G. Hot flashes in a young girl: a wake-up call concerning Serenoa repens use in children. Pediatrics 2012;130(5):e1374-e1376.
  17. Braeckman J. The extract of Serenoa repens in the treatment of benign prostatic hyperplasia: a multicenter open study. Current Therapeutic Research 1994;55(7):776-785. DOI
  18. Jipescu D, Patel A, Bohra H, Pientka A. Rare case of saw palmetto induced heart block. JACC 2017;69(11) supplement:2310.
  19. Morabito P, Miroddi M, Giovinazzo S, Spina E, Calapai G. Serenoa repens as an endocrine disruptor in a 10-year-Old young girl: a new case report. Pharmacology. 2015;96(1-2):41-3. doi: 10.1159/000431327.
  20. Gammoudi R, Ameur K, Ouni B, et al. Fixed drug eruption to Serenoa repens: first case report and consideration of the use of herbal medicine. Dermatol Ther 2020 Aug 29:e14247.
  21. Paulis G, Paulis A, Perletti G. Serenoa repens and its effects on male sexual function. A systematic review and meta-analysis of clinical trials. Arch Ital Urol Androl 2021;93(4):475-480. PubMed
  22. Venkateswaran S, Declet-Bauzo R, Shodeinde M, Gilford P. Postoperative Retroperitoneal Hematoma: A Case of Saw Palmetto and the Importance of Primary Care Intervention. HCA Healthc J Med 2020;1(5):279-282. PubMed

See these in context on the Saw Palmetto monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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