Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Sharp Thought Ingredients & Drug Interactions

by Country Life

Sharp Thought label
See full label image
Capsule Category: Fat/fatty Acid
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Sharp Thought against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Sharp Thought is a dietary supplement by Country Life with 2 active ingredients. Its ingredients are commonly taken for memory and cognitive support, age-related cognitive decline, attention and focus (adhd).Based on those ingredients, 219 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Phosphatidylserine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Sharp Thought by Country Life

Ask about any prescription or over-the-counter medication and we check it for interactions with Sharp Thought by Country Life — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Sharp Thought by Country Life

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • “Sharp-PS Gold” is listed as a grouped ingredient — the label gives one combined amount (223 mg) without saying how much of each component you get.

Sharp Thought has two active ingredients: docosahexaenoic acid, an omega-3 fatty acid, and phosphatidylserine (supplied as Sharp-PS Gold, a branded form). The rest of the capsule is made up of inactive ingredients like cellulose, hypromellose, and silica, which help hold the formula together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Memory and cognitive support.
  • We looked for evidence on: Age-related cognitive decline, Cognitive function, Attention deficit-hyperactivity disorder (ADHD), Mental clarity, Focus, Brain health — and 1 related terms.
  • The strongest evidence on file: Phosphatidylserine is rated "Possibly Effective" for Age-related cognitive decline (Natural Medicines).
  • Also on file: Phosphatidylserine is rated "Insufficient Reliable Evidence To Rate" for Attention deficit-hyperactivity disorder (ADHD), Cognitive function.

Phosphatidylserine is possibly effective for age-related cognitive decline and Alzheimer's disease, according to the evidence we have. For other uses listed — athletic performance, attention problems, general cognition, and dementia — the evidence isn't strong enough to make a confident claim.

We hold no effectiveness data for docosahexaenoic acid in this product.

The evidence, ingredient by ingredient Phosphatidylserine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Phosphatidylserine is generally well tolerated in studies, though long-term safety hasn't been fully established. The most common side effects are flatulence, stomach upset, headache, trouble sleeping, and nausea.

Insomnia is more likely at higher doses (around 600 mg), and digestive upset can show up at 200–300 mg per day. The safety data advises against use during pregnancy and while breastfeeding, because there isn't enough information to know it's safe in those situations.

Talk with your doctor or pharmacist about your individual circumstances if you're pregnant, planning to become pregnant, or nursing.

Side effects, ingredient by ingredient Phosphatidylserine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Phosphatidylserine.
  • The most serious interaction on file is rated Moderate.
  • For scale: 219 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Sharp Thought, double-check with your pharmacist if you use anticholinergic drugs (like medications for overactive bladder or Parkinson's) or cholinergic drugs (like some dementia treatments) — phosphatidylserine may affect how these work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help with age-related memory decline or early Alzheimer's disease, but the evidence for other cognitive uses is still unclear. If you take anticholinergic or cholinergic medications, check with your pharmacist first — phosphatidylserine could theoretically interfere with how they work.

Avoid it in pregnancy and while breastfeeding unless your doctor says otherwise.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sharp Thought, straight from the product label.

Brand Country Life
Barcode (UPC) 015794049487
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Apr 24, 2025
DSLD ID 327619
Product type Fat/fatty Acid
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sharp Thought by Country Life, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
015794049487
IngredientAmount% DV
Docosahexaenoic Acid8 mg--
Phosphatidylserine100 mg--
Sharp-PS Gold223 mg--

Other ingredients: Microcrystalline Cellulose, Hypromellose, Maltodextrin, Magnesium Stearate, Stearic Acid, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

SharpThought contains a very special conjugated complex of phosphatidylserine (PS) and DHA and Omega-3 fatty acid (Sharp-PS Gold).

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Yes Certified Gluten-free by GFCO.org No yeast, wheat or milk No salt or preservatives No artificial colors, flavors or sweeteners Purity tested for heavy metals including mercury.

Yes Manufacturing supports wind power This product has been manufactured at a GMP Registered facility.

Triple Action Clinically shown to: Support memory Support faster recall Increase mental clarity Based on three (3) capsules daily.

Certified Gluten-free

Our pledge of integrity Authenticity Cleanliness Freshness Consistency Accuracy

General Statements

Yes Recyclable Packaging

Brand IP Statement(s)

Sharp-PS is a registered trademark of Frutarom.

Established 1971 Country Life

Seals/Symbols

Certified B Corporation Certified Gluten Free GFCO.org

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults take one (1) capsule one (1) to three (3) times daily with food. As a reminder, discuss the supplements and medications that you take with your health care providers.

Precautions

Contains soy and fish (blue whiting, herring).

Caution: If you are pregnant or nursing, under medical care, taking medication, have a medical condition or planning surgery, consult a doctor before using this product.

Stop using and consult a doctor if any adverse reactions occur. Do not exceed recommended dosage. Do not accept if seal is broken.

Keep out of the reach of children.

Storage

Store in a dry place between 59 degrees - 86 degrees F, avoiding exposure to light.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Sharp Thought by Country Life label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Sharp Thought label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Sharp Thought by Country Life

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sharp-PS Gold

223 mg per serving Form: Conjugated Phosphatidylserine-Docosahexaenoic Acid Complex

Other (inactive) ingredients: Microcrystalline Cellulose, Hypromellose, Maltodextrin, Magnesium Stearate, Stearic Acid, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Sharp Thought by Country Life Drug Interactions

Want to check YOUR meds against Sharp Thought?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
219Drugs
219 Moderate

Ingredients driving the most interactions

Phosphatidylserine 219

Individual Drug Interactions

The ingredients in Sharp Thought interact with 219 drugs. Click any drug to see the details.

1 of the 2 ingredients in Sharp Thought interact with drugs. Each result below shows which ingredient is responsible. Phosphatidylserine

Each ingredient & the kinds of drugs it affects

For each ingredient in Sharp Thought with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Phosphatidylserine2 drug types · 219 drugs

Anticholinergic Drugs

Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically interfere with the activity of anticholinergic agents.

Likelihood Possible Evidence B
Cholinergic Drugs

Theoretically, phosphatidylserine might have additive effects with cholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically lead to additive cholinergic effects when used with cholinergic drugs.

Likelihood Possible Evidence B
Phosphatidylserine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Sharp Thought, from the product label.

Country Life

See all Country Life products
Name
Country Life, LLC
Street Address
180 Vanderbilt Motor Parkway
City
Hauppauge
State
NY
ZipCode
11788
Web Address
CountryLifeVitamins.com
Pharmacist Counseling Corner

Sharp Thought by Country Life: Common Questions

Does Sharp Thought by Country Life interact with any medications?
Yes. Based on its ingredients, Sharp Thought has a known interaction with 219 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Sharp Thought contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is phosphatidylserine, and what does it do?
Phosphatidylserine is a naturally occurring compound thought to boost acetylcholine levels in your brain — a chemical involved in memory and learning. That's why it's included in products aimed at supporting cognition and memory.
Does this product actually work for memory problems?
For age-related memory decline and Alzheimer's disease, phosphatidylserine is possibly effective based on available evidence. For other uses like general cognition or ADHD, the evidence isn't strong enough yet to say either way.
What side effects might I experience?
Most people tolerate it well, but the most common side effects are gas, stomach upset, headache, trouble sleeping, and nausea. Insomnia risk goes up at higher doses, and digestive issues can happen even at lower doses.
Can I take this if I'm pregnant or breastfeeding?
The safety data advises against it in both pregnancy and breastfeeding because there isn't enough information to know it's safe. Talk with your doctor or pharmacist about whether it's right for your situation.
What's docosahexaenoic acid, and why is it in here?
It's an omega-3 fatty acid often included in brain-health supplements. We don't hold effectiveness data for this ingredient in this specific product, so I can't tell you what role it's meant to play here.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sharp Thought label
Go deeper

The Full Monographs Behind Sharp Thought’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Phosphatidylserine

Interacts with 219 drugs

Phosphatidylserine is a natural fat-like compound found in cell membranes, especially in the brain, and it is sold mainly to support memory and thinking. Some research suggests possible bene...

Read the full Phosphatidylserine monograph →
Sources

Sources & How We Checked

Sharp Thought's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 9 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Phosphatidylserine 9 references
  1. Crook T, Petrie W, Wells C, Massari DC. Effects of phosphatidylserine in Alzheimer's disease. Psychopharmacol Bull 1992;28:61-6.
  2. Pepping J. Phosphatidylserine. Am J Health-Syst Pharm 1999;56:2038,2043-4.
  3. Kidd PM. Phosphatidylserine; Membrane nutrient for memory. A clinical and mechanistic assessment. Altern Med Rev 1996;1:70-84.
  4. Kim HY, Akbar M, Lau A, et al. Inhibition of neuronal apoptosis by docosahexaenoic acid (22:6n-3). Role of phosphatidylserine in antiapoptotic effect. J Biol Chem 2000;275:35215-23.. PubMed
  5. Zanotti A, Valzelli L, Toffano G. Chronic phosphatidylserine treatment improves spatial memory and passive avoidance in aged rats. Psychopharmacology (Berl) 1989;99:316-21.. PubMed
  6. Schreiber S, Kampf-Sherf O, Gorfine M, et al. An open trial of plant-source derived phosphatydilserine for treatment of age-related cognitive decline. Isr J Psychiatry Relat Sci 2000;37:302-7.
  7. Pepping, J. Phosphatidylserine. Am J Health Syst.Pharm. 10-15-1999;56(20):2038, 2043-2038, 2044.
  8. Monteverde, A., Gnemmi, P., Rossi, F., Monteverde, A., and Finali, G. C. Selegiline in the treatment of mild to moderate Alzheimer-type dementia. Clin.Ther 1990;12(4):315-322.
  9. Vakhapova V, Cohen T, Richter Y, Herzog Y, Kam Y, Korczyn AD. Phosphatidylserine containing omega-3 Fatty acids may improve memory abilities in nondemented elderly individuals with memory complaints: results from an open-label extension study. Dement Geri PubMed

See these in context on the Phosphatidylserine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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