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Dietary supplement

Sheep Sorrel Alcohol Free Ingredients & Drug Interactions

by Hawaii Pharm

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Sheep Sorrel Alcohol Free is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for sinus and respiratory congestion, digestive upset, fever.Based on those ingredients, 169 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sheep Sorrel Herb Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Sheep Sorrel Alcohol Free by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Sheep Sorrel Alcohol Free contains one active ingredient: Sheep Sorrel Herb Extract, Dry — a concentrated form of the plant traditionally used for various conditions. The liquid also contains glycerin and water as inactive ingredients to deliver the extract.

Sorrel is a plant in the buckwheat family, and the extract concentrates its compounds. Because this is labeled alcohol-free, the extract was prepared without ethanol, though lab studies on sorrel's effects have used ethanol versions.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Sorrel product and its label doesn't state a use — see Sorrel's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The data we hold doesn't establish that sorrel is effective for any condition. For bronchitis, breast cancer, and rhinosinusitis (sinus inflammation), the evidence is rated insufficient — meaning we don't have enough reliable studies to know whether it works or doesn't.

If you're considering this product for a specific health goal, your doctor or pharmacist can discuss what the current research actually supports and what alternatives might be better studied.

The evidence, ingredient by ingredient Sorrel

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sorrel is generally well tolerated in food amounts, but the safety facts highlight two key concerns. First, sorrel is high in oxalates — compounds that, in large or concentrated doses, can build up in your body and potentially damage your kidneys.

A case report documents one child who developed kidney inflammation (tubulointerstitial nephritis) after consuming an unknown amount of wild sorrel. Second, some people allergic to weed pollen may react to sorrel pollen exposure, and up to 19% of people with weed allergies could have cross-sensitivity.

When used in combination with other herbs, sorrel has been reported to cause nausea and an unpleasant aftertaste. For pregnancy and breastfeeding, the safety data rates sorrel as possibly safe, but research on medicinal or concentrated amounts is sparse.

The safety notes advise avoiding concentrated supplements while breastfeeding. If you're pregnant or nursing and want to use this product, talk it over with your doctor or pharmacist so they can weigh the limited data and your individual situation.

Side effects, ingredient by ingredient Sorrel

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Sorrel.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 169 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before combining this product with blood thinners (anticoagulants and antiplatelet drugs) — sorrel may add to their effects and raise bleeding risk. Also confirm it's safe with fexofenadine (Allegra) and other OATP substrates, a broad drug family that includes some heart, cancer, and allergy medicines — sorrel may reduce how well your body absorbs them.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is a single-ingredient sorrel extract with documented interactions affecting a large number of medications — particularly blood thinners and allergy/heart medicines. If you take any prescription drugs, especially anticoagulants or antihistamines, you need to check with your doctor or pharmacist before starting it.

The evidence for sorrel's effectiveness isn't established in our data, and the high oxalate content is a safety concern at higher doses.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 14, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sheep Sorrel Alcohol Free, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 840253648402
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Dec 14, 2023
DSLD ID 300932
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sheep Sorrel Alcohol Free by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
840253648402
IngredientAmount% DV
Sheep Sorrel Herb Extract, Dry1156 mg--

Other ingredients: Glycerin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Hawaii Pharm Herbal Extract Highest quality since 2008

Suggested/Recommended/Usage/Directions

Suggested use: Shake well before using. For adults add about 20-30 drops (0.7-1 mL, one full squeeze of the dropper bulb) to some juice or water, up to 4 times a day.

Precautions

Warning: We recommend to seek expert medical advice before taking.

Do not use if you are allergic to any ingredients.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.

May affect the ability to drive and operate machinery. May have contraindications, can cause side effects and adverse reactions. Do not use if seal is broken or missing.

Keep out of the reach of children!

Storage

Store in a cool dry place.

Seals/Symbols

cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.

C2H5OH Alcohol free USA Made in United States of America

FDA Disclaimer Statement

This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Scan this QR-code to get 15% discount on your next purchase. Limited time deal.

Formula

Rumex acetosella

Formulation

Only natural ingredients Purity is laboratory tested and verified

All the raw materials are gluten-free by their nature No artificial colors, flavors, or preservatives

Not tested on animals

C2H5OH Alcohol free

Made in USA, Hawaii

FDA Statement of Identity

Herbal Supplement

See for yourself

Sheep Sorrel Alcohol Free by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Sheep Sorrel Alcohol Free by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Sheep Sorrel Herb Extract, Dry

Interacts with
169 drugs
1156 mg per serving Form: Rumex acetosella Herb Extract, Dry

Sorrel is a tangy, leafy herb used in cooking and traditional medicine, often for congestion, digestion, and inflammation. Solid human evidence for an...

Sheep Sorrel Herb Extract, Dry monograph & interactions

Other (inactive) ingredients: Glycerin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Sheep Sorrel Alcohol Free by Hawaii Pharm Drug Interactions

Want to check YOUR meds against Sheep Sorrel Alcohol Free?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
169Drugs
169 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Sheep Sorrel Alcohol Free with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Sheep Sorrel Herb Extract, Dry3 drug types · 169 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
In vitro, sorrel has been shown to inhibit platelet aggregation. However, this effect has not been reported in humans.

Likelihood Possible Evidence D
Fexofenadine (Allegra)

Sorrel might reduce the effectiveness of fexofenadine by reducing its absorption from the gut.
In vitro research shows that an ethanol extract of sorrel inhibits organic anion-transporting polypeptide 1A2 (OATP1A2), which transports fexofenadine from the intestine into cells. In rats, concomitant administration of sorrel extract with fexofenadine reduces oral absorption of fexofenadine and the area under the plasma concentration-time curve (AUC).

Likelihood Likely Evidence D
Organic Anion-Transporting Polypeptide Substrates (Oatp)

Sorrel might reduce the effectiveness of OATP substrates by reducing their absorption from the gut.
In vitro research shows that sorrel inhibits OATP1A2. Theoretically it may inhibit other OATPs. The OATPs are expressed in the small intestine and liver and transport drugs into cells. Inhibition of OATP may reduce the bioavailability of oral drugs that are substrates of OATP.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Sheep Sorrel Alcohol Free, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
Street Address
510 Sumner St. Ste. 613
City
Honolulu
State
HI
ZipCode
96817
Phone Number
888-854-2924
Web Address
www.hawaiipharm.com
Pharmacist Counseling Corner

Sheep Sorrel Alcohol Free by Hawaii Pharm: Common Questions

Does Sheep Sorrel Alcohol Free by Hawaii Pharm interact with any medications?
Yes. Based on its ingredients, Sheep Sorrel Alcohol Free has a known interaction with 169 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Sheep Sorrel Alcohol Free contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this product work for bronchitis, breast cancer, or sinus problems?
The evidence we hold doesn't establish that sorrel is effective for any of these conditions. The data rates the evidence as insufficient — we simply don't have enough reliable studies to say whether it helps or doesn't. Ask your doctor or pharmacist what treatments have stronger evidence for what you're dealing with.
Is sorrel safe if I'm pregnant or breastfeeding?
Sorrel is rated possibly safe in pregnancy and lactation, but research on medicinal or concentrated amounts is limited. The safety data specifically advises avoiding concentrated supplements while breastfeeding. Talk with your doctor or pharmacist about whether this product is right for you during this time — they can discuss the limited data with your specific situation in mind.
What are the side effects I should know about?
The main concerns are kidney-related: sorrel is high in oxalates, which can accumulate and damage your kidneys at large or concentrated doses. One child developed kidney inflammation after consuming wild sorrel. Some people allergic to weed pollen may react to sorrel, and nausea and aftertaste have been reported when it's combined with other herbs. If you have a history of kidney problems, mention this product to your doctor or pharmacist first.
Why does this product interact with so many medications?
Sorrel blocks a protein (OATP) in your gut and liver that normally absorbs many different types of medications into your body. When sorrel blocks this protein, your body absorbs those drugs less effectively — making them potentially less powerful. That's why it affects such a large range of prescriptions across different categories.
Can I take this if I'm on Allegra (fexofenadine)?
Not without checking first. Lab studies show sorrel inhibits the protein responsible for absorbing fexofenadine, which could make the allergy medication less effective. Talk with your doctor or pharmacist before starting this product if you use Allegra or any other antihistamine.
Is this product safe to combine with blood thinners?
No — not without discussing it with your doctor first. Sorrel has a moderate-severity interaction with blood thinners and can theoretically add to their effects, raising your bleeding risk. If you take warfarin, apixaban, aspirin, or any other blood thinner, mention this product to your prescriber before you use it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Sheep Sorrel Alcohol Free is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sheep Sorrel Alcohol Free label
Go deeper

The Full Monographs Behind Sheep Sorrel Alcohol Free’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Sheep Sorrel Alcohol Free's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sorrel 8 references
  1. Neubauer N, Marz RW. Placebo-controlled, randomized, double-blind, clincal trial with Sinupret sugar coated tablets on the basis of a therapy with antibiotics and decongestant nasal drops in acute sinusitis. Phytomedicine 1994;1:177-81.
  2. Marz RW, Ismail C, Popp MA. Action profile and efficacy of a herbal combination preparation for the treatment of sinusitis. Wien Med Wochenschr 1999;149:202-8.
  3. Zick, S. M., Sen, A., Feng, Y., Green, J., Olatunde, S., and Boon, H. Trial of Essiac to ascertain its effect in women with breast cancer (TEA-BC). J Altern Complement Med 2006;12(10):971-980. PubMed
  4. Sanz, P. and Reig, R. Clinical and pathological findings in fatal plant oxalosis. A review. Am J Forensic Med Pathol. 1992;13(4):342-345. PubMed
  5. Gniazdowska, B., Doroszewska, G., and Doroszewski, W. [Hypersensitivity to weed pollen allergens in the region of Bygdoszcz]. Pneumonol.Alergol.Pol. 1993;61(7-8):367-372.
  6. Selçuk SN, Gülhan B, Düzova A, Teksam Ö. Acute tubulointerstitial nephritis due to large amount of sorrel (Rumex acetosa) intake. Clin Toxicol (Phila) 2015;53(5):497. PubMed
  7. Ahn JH, Kim J, Rehman NU, Kim HJ, Ahn MJ, Chung HJ. Effect of Rumex Acetosa Extract, a Herbal Drug, on the Absorption of Fexofenadine. Pharmaceutics. 2020;12(6):E547. PubMed
  8. Jeong D, Irfan M, Lee DH, Hong SB, Oh JW, Rhee MH. Rumex acetosa modulates platelet function and inhibits thrombus formation in rats. BMC Complement Med Ther. 2020;20(1):98. PubMed

See these in context on the Sorrel monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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