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Dietary supplement

Shepherd's Purse Alcohol Free Ingredients & Drug Interactions

by Hawaii Pharm

Shepherd's Purse Alcohol Free label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Shepherd's Purse Alcohol Free against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Shepherd's Purse Alcohol Free is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for heavy or prolonged menstrual bleeding, minor bleeding (nosebleeds, wounds), mild diuretic.Based on those ingredients, 264 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Shepherd's Purse Seedpod Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Shepherd's Purse Alcohol Free by Hawaii Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Shepherd's Purse Alcohol Free by Hawaii Pharm — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Shepherd's Purse Alcohol Free by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: shepherd's purse seedpod extract in a liquid (alcohol-free) form. Shepherd's purse is an herb traditionally used to address heavy menstrual bleeding and postpartum bleeding, though reliable evidence for these uses is limited.

The inactive ingredients are glycerin and water.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: support for menstrual and postpartum health.
  • We looked for evidence on: Menorrhagia, Postpartum complications, heavy bleeding, postpartum hemorrhage.
  • The closest evidence on file: Shepherd's Purse is rated "Insufficient Reliable Evidence To Rate" for Postpartum complications (Natural Medicines).
  • Also on file: Shepherd's Purse is rated "Insufficient Reliable Evidence To Rate" for Menorrhagia.

The evidence we hold doesn't establish that shepherd's purse is effective for its traditional uses. Both postpartum complications and heavy menstrual bleeding (menorrhagia) carry a rating of insufficient reliable evidence to rate, meaning the data supporting it isn't strong enough to confirm whether it works for these purposes.

The evidence, ingredient by ingredient Shepherd's Purse

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Short-term use by adults in small amounts is generally well tolerated, though human safety data are limited. Adverse effects traditionally linked to shepherd's purse include sedation, changes in blood pressure, abnormal thyroid function, irregular menstruation, and heart palpitations.

Avoid this product during pregnancy — it may stimulate the uterus. Don't use it while breastfeeding; there isn't enough safety information.

Side effects, ingredient by ingredient Shepherd's Purse

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Shepherd's Purse.
  • The most serious interaction on file is rated Moderate.
  • For scale: 264 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, check whether you take any sedating medications (like sleep aids, anxiety meds, or opioids) or thyroid hormone replacement therapy. Both can have interactions with shepherd's purse.

Use the medication checker below to confirm your exact drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a single-herb supplement with limited evidence of effectiveness and a couple of important medication interactions to watch for. If you take sedating drugs or thyroid hormone, check with your pharmacist first.

Pregnant and breastfeeding people should avoid it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 14, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Shepherd's Purse Alcohol Free, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 840253648587
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Dec 14, 2023
DSLD ID 300934
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Shepherd's Purse Alcohol Free by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
840253648587
IngredientAmount% DV
Shepherd's Purse Seedpod Extract, Dry1156 mg--

Other ingredients: Glycerin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Hawaii Pharm Herbal Extract Highest quality since 2008

Suggested/Recommended/Usage/Directions

Suggested use: Shake well before using. For adults add about 20-30 drops (0.7-1 mL, one full squeeze of the dropper bulb) to some juice or water, up to 4 times a day.

Precautions

Warning: We recommend to seek expert medical advice before taking.

Do not use if you are allergic to any ingredients.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.

May affect the ability to drive and operate machinery. May have contraindications, can cause side effects and adverse reactions. Do not use if seal is broken or missing.

Keep out of the reach of children!

Storage

Store in a cool dry place.

Seals/Symbols

cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.

C2H5OH Alcohol free USA Made in United States of America

FDA Disclaimer Statement

This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Scan this QR-code to get 15% discount on your next purchase. Limited time deal.

Formula

Capsella bursa-pastoris

Formulation

Only natural ingredients Purity is laboratory tested and verified

All the raw materials are gluten-free by their nature No artificial colors, flavors, or preservatives

Not tested on animals

C2H5OH Alcohol free

Made in USA, Hawaii

FDA Statement of Identity

Herbal Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Shepherd's Purse Alcohol Free by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Shepherd's Purse Alcohol Free label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Shepherd's Purse Alcohol Free by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Shepherd's Purse Seedpod Extract, Dry

Interacts with
264 drugs
1156 mg per serving

Shepherd's purse is a traditional herb most often used to help slow heavy menstrual bleeding and other minor bleeding, but solid human research is ver...

Shepherd's Purse Seedpod Extract, Dry monograph & interactions

Other (inactive) ingredients: Glycerin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Shepherd's Purse Alcohol Free by Hawaii Pharm Drug Interactions

Want to check YOUR meds against Shepherd's Purse Alcohol Free?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
264Drugs
264 Moderate

Ingredients driving the most interactions

Shepherd's Purse Seedpod Extract, Dry 264

Individual Drug Interactions

The ingredients in Shepherd's Purse Alcohol Free interact with 264 drugs. Click any drug to see the details.

1 of the 1 ingredient in Shepherd's Purse Alcohol Free interact with drugs. Each result below shows which ingredient is responsible. Shepherd's Purse Seedpod Extract, Dry

Each ingredient & the kinds of drugs it affects

For each ingredient in Shepherd's Purse Alcohol Free with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Shepherd's Purse Seedpod Extract, Dry2 drug types · 264 drugs

Cns Depressants

Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, concomitant use may interfere with thyroid dysfunction therapy.

Likelihood Possible Evidence D
Shepherd's Purse Seedpod Extract, Dry full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Shepherd's Purse Alcohol Free, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
Street Address
510 Sumner St. Ste. 613
City
Honolulu
State
HI
ZipCode
96817
Phone Number
888-854-2924
Web Address
www.hawaiipharm.com
Pharmacist Counseling Corner

Shepherd's Purse Alcohol Free by Hawaii Pharm: Common Questions

Does Shepherd's Purse Alcohol Free by Hawaii Pharm interact with any medications?
Yes. Based on its ingredients, Shepherd's Purse Alcohol Free has a known interaction with 264 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Shepherd's Purse Alcohol Free contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No. The safety data advise against shepherd's purse during pregnancy because it may stimulate the uterus. Don't use it while breastfeeding either — there isn't enough information to know it's safe.
Does this product actually work for heavy periods or postpartum bleeding?
The evidence we hold isn't strong enough to confirm it. Both uses carry a rating of insufficient reliable evidence, so we can't say whether it's effective for these purposes.
What are the side effects?
Shepherd's purse is generally well tolerated in small amounts for short-term use, though human safety data are limited. Adverse effects traditionally thought to be linked to it include sedation, blood pressure changes, thyroid problems, irregular periods, and heart palpitations.
Why does this interact with so many medications?
This product's one ingredient interacts with two drug types — sedating medications and thyroid hormones. Those two categories together cover 264 individual medications, which is why the number looks large. Check your exact prescriptions with the tool on this page.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Shepherd's Purse Alcohol Free is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Shepherd's Purse Alcohol Free label
Go deeper

The Full Monographs Behind Shepherd's Purse Alcohol Free’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Shepherd's Purse

Interacts with 264 drugs

Shepherd's purse is a traditional herb most often used to help slow heavy menstrual bleeding and other minor bleeding, but solid human research is very limited. Because it may affect blood c...

Read the full Shepherd's Purse monograph →
Sources

Sources & How We Checked

Shepherd's Purse Alcohol Free's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Shepherd's Purse 4 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Naafe M, Kariman N, Keshavarz Z, et al. Effect of hydroalcoholic extracts of Capsella bursa-pastoris on heavy menstrual bleeding: A randomized clinical trial. J Altern Complement Med. 2018;24(7):694-700. PubMed
  4. Ghalandari S, Kariman N, Sheikhan Z, et al. Effect of hydroalcoholic extract of Capsella bursa pastoris on early postpartum hemorrhage: A clinical trial study. J Altern Complement Med. 2017;23(10):794-799.

See these in context on the Shepherd's Purse monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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