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Dietary supplement

Shred Research Ingredients & Drug Interactions

by Sarms Pharm (SP)

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Shred Research is a dietary supplement by Sarms Pharm (SP) with 3 active ingredients. Its ingredients are commonly taken for muscle building, strength gains, fat loss / body recomposition.Based on those ingredients, 612 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Ostarine MK-2866, Andarine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Shred Research by Sarms Pharm (SP)

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Shred Research contains three active ingredients, each a selective androgen receptor modulator (SARM) or related research compound: Andarine (S-4), Stenabolic SR-9009, and Ostarine MK-2866. These are investigational drugs designed to affect how your body builds and uses muscle, but none are approved by the FDA and none are legal to sell as dietary supplements.

The product contains no inactive ingredients listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The label doesn't state a purpose we can grade — see each ingredient's own graded uses on its monograph instead.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence supporting these ingredients is not established. For Andarine, Stenabolic, and Ostarine, the data we hold shows insufficient reliable evidence to rate their effectiveness for athletic performance, weight management, muscle wasting, or any other claimed use.

These are research compounds without proven benefit in humans.

The evidence, ingredient by ingredient Andarine Stenabolic Ostarine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

This product carries serious safety warnings. Andarine and Ostarine are unapproved investigational drugs with known risks: both may damage the liver, increase markers of liver injury, and raise the risk of heart attack or stroke according to FDA warnings.

Ostarine has caused abdominal pain, nausea, diarrhea, and in clinical trials, increases in liver enzymes in a meaningful portion of users. Stenabolic is an untested research chemical with no human safety data at all.

None of these ingredients should be used during pregnancy—Andarine and Ostarine affect hormone pathways, and Stenabolic is rated possibly unsafe with no safety information. Breastfeeding is also contraindicated for all three due to lack of safety data.

Side effects, ingredient by ingredient Andarine Stenabolic Ostarine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Ostarine, Andarine.
  • The most serious interaction on file is rated Moderate.
  • For scale: 613 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take androgens (androgenic drugs), hepatotoxic medications, drugs that induce or inhibit CYP3A4 metabolism, probenecid, rifampin, or substrates of CYP2C9. The moderate-severity interactions with androgens and liver-toxic drugs are the most serious concerns.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Shred Research is not a legal supplement; it contains three unapproved research compounds with significant gaps in human safety data and documented risks to your liver and heart. The evidence supporting their effectiveness is insufficient.

If you're considering this product, talk with your doctor or pharmacist first—do not start it without personalized medical guidance, and be honest with them about any medications you take, since the interactions are substantial.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 26, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Shred Research, straight from the product label.

Brand Sarms Pharm (SP)
Net contents 90 Cap(s)
Market status On market
Date entered into DSLD Dec 26, 2020
DSLD ID 242059
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses No Claim
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Shred Research by Sarms Pharm (SP), sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0 Not Present
Maximum serving Sizes:
0 Not Present
IngredientAmount% DV
Andarine50 mg--
Stenabolic SR-900930 mg--
Ostarine MK-286630 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Research Product

90 Caps / 30 mg / 30 mg / 50 mg per 3 Caps

See for yourself

Shred Research by Sarms Pharm (SP) label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Shred Research by Sarms Pharm (SP)

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size0 Not Present Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Andarine

Interacts with
9 drugs
50 mg per serving

Andarine (S-4) is a synthetic selective androgen receptor modulator (SARM) that is not approved by the FDA for human use and is banned in sports. It i...

Andarine monograph & interactions

Stenabolic SR-9009

No known
interactions
30 mg per serving

Stenabolic (also called SR9009) is an experimental research chemical, not a true dietary supplement, herb, or approved drug. It is sold online for fat...

Stenabolic SR-9009 monograph & interactions

Ostarine MK-2866

Interacts with
611 drugs
30 mg per serving

Ostarine (also called MK-2866 or enobosarm) is an experimental, unapproved drug known as a SARM (selective androgen receptor modulator), not a true di...

Ostarine MK-2866 monograph & interactions
Interaction report

Shred Research by Sarms Pharm (SP) Drug Interactions

Want to check YOUR meds against Shred Research?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
612Drugs
441 Moderate 171 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Shred Research with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Ostarine MK-28666 drug types · 611 drugs

Cytochrome P450 3A4 (Cyp3A4) Inducers

Theoretically, concomitant use of ostarine with CYP3A4 inducers could decrease the clinical effects of ostarine.
Ostarine is partially metabolized by CYP3A4. Clinical research shows that taking rifampin, a potent inducer of CYP3A4, reduces the maximum plasma concentration of ostarine by 23% and the area under the curve by 43%.

Likelihood Possible Evidence B
Hepatotoxic Drugs

Theoretically, concomitant use with hepatotoxic drugs might increase the risk of adverse hepatotoxic effects.
Some clinical research shows that ostarine can increase alanine aminotransferase, a marker of liver damage, in some patients. Additionally, the U.S. Food and Drug Administration warns that supplements containing SARMs, such as ostarine, have been associated with reports of liver toxicity and there are at least two reports of drug-induced liver injury attributed to the use of ostarine.

Likelihood Possible Evidence D
Probenecid (Benemid)

Theoretically, concomitant use of ostarine with probenecid could increase the effects and adverse effects of ostarine.
Clinical research shows that probenecid increases ostarine levels and slows the clearance of ostarine, likely via inhibition of UDP-glucuronosyltransferase (UGT). Ostarine is partially metabolized by UGT.

Likelihood Possible Evidence B
Rifampin (Rifadin)

Theoretically, concomitant use of ostarine with rifampin could decrease the clinical effects of ostarine.
Clinical research shows that taking rifampin with ostarine reduces the maximum plasma concentration of ostarine by 23% and the area under the curve by 43%. Ostarine is partially metabolized by cytochrome P450 3A4 (CYP3A4), and rifampin is a potent CYP3A4 inducer.

Likelihood Possible Evidence B
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, ostarine might increase levels of drugs metabolized by CYP2C9, although clinical research suggests this is not clinically relevant.
Although in vitro research suggests that ostarine inhibits CYP2C9, more robust clinical research shows that ostarine does not significantly affect CYP2C9.

Likelihood Unlikely Evidence B
Cytochrome P450 3A4 (Cyp3A4) Inhibitors

Theoretically, concomitant use of ostarine with CYP3A4 inhibitors could increase the effects and adverse effects of ostarine, although this is unlikely to be clinically significant.
Ostarine is partially metabolized by CYP3A4. However, clinical research shows that taking itraconazole, a potent inhibitor of CYP3A4, had minimal effects on the levels of ostarine in the body.

Likelihood Unlikely Evidence B

Andarine1 drug type · 9 drugs

Androgens

Due to its androgenic properties, Andarine (S-4) may theoretically interact with other androgenic drugs, potentially increasing the risk of side effects associated with androgenic activity (source: https://pubmed.ncbi.nlm.nih.gov/12604714/). These side effects can include masculinization, virilization, acne, hair loss, increased libido, aggression, mood changes, and liver toxicity.

Likelihood Possible Evidence C
The maker

Brand information

Manufacturer and brand details for Shred Research, from the product label.

Sarms Pharm (SP)

See all Sarms Pharm (SP) products
Name
Sarms Pharm (SP)
Pharmacist Counseling Corner

Shred Research by Sarms Pharm (SP): Common Questions

Does Shred Research by Sarms Pharm (SP) interact with any medications?
Yes. Based on its ingredients, Shred Research has a known interaction with 612 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Shred Research contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this product legal to buy?
No. Andarine and Ostarine are unapproved investigational drugs not authorized for human use, and Stenabolic is a research chemical. The FDA has warned against supplements containing these compounds. Selling them as dietary supplements violates federal law.
Can I take this if I'm pregnant or breastfeeding?
No. Andarine and Ostarine affect hormone pathways and must be avoided in pregnancy. Stenabolic is rated possibly unsafe with no safety data available. All three lack safety information for breastfeeding and should not be used.
What are the main side effects I should know about?
Ostarine has caused nausea, abdominal pain, diarrhea, and constipation in studies. More seriously, both Ostarine and Andarine may damage your liver and increase the risk of heart attack or stroke. Andarine may cause virilization, acne, and hair loss. Stenabolic has no human safety data, so its side effects are unknown.
Does this product actually work for muscle building or fat loss?
The evidence isn't established. Our data shows insufficient reliable evidence to rate any of these three ingredients for athletic performance, weight loss, or muscle gain in humans.
What happens if these ingredients affect my liver?
Both Andarine and Ostarine can cause increases in liver enzymes (ALT), a marker of liver damage. In clinical trials, 7–21% of patients taking Ostarine showed elevated liver enzymes depending on the dose. The FDA has warned that these compounds carry the risk of hepatotoxicity—serious liver injury—and no thorough safety evaluations have been completed.
Should I have my liver checked if I take this?
That's a question for your doctor. Given the documented risk of liver injury with these ingredients, baseline and regular liver function testing would be prudent if anyone were to consider use—but you should discuss all of this with your healthcare provider before starting, since these are unapproved drugs.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Shred Research label
Sources

Sources & How We Checked

Shred Research's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Andarine 1 reference
  1. FDA. FDA Warns against using SARMs in body building products. October 2017. Available at: https://www.fda.gov/newsevents/newsroom/fdainbrief/ucm583021.htm.

See these in context on the Andarine monograph →

Stenabolic 1 reference
  1. What Should Tested Athletes Know About GW1516? Education, Spirit of Sport. U.S. Anti-Doping Agency (USADA). September 24, 2019. Available at: https://www.usada.org/spirit-of-sport/education/what-should-athletes-know-gw1516/

See these in context on the Stenabolic monograph →

Ostarine 10 references
  1. Warning Letter: Ironmag Labs 10/23/17. FDA Inspections, Compliance, Enforcement, and Criminal Investigations, October 23, 2017. https://www.fda.gov/iceci/enforcementactions/warningletters/2017/ucm582464.htm Accessed: November 1, 2017
  2. Warning Letter: Panther Sports Nutrition 10/23/17. FDA Inspections, Compliance, Enforcement, and Criminal Investigations, October 23, 2017. https://www.fda.gov/iceci/enforcementactions/warningletters/2017/ucm581630.htm. Accessed: November 1, 2017
  3. Warning Letter: Infantry Labs LLC 10/23/17. FDA Inspections, Compliance, Enforcement, and Criminal Investigations, October 23, 2017. https://www.fda.gov/iceci/enforcementactions/warningletters/2017/ucm582685.htm. Accessed: November 1, 2017
  4. Dobs AS, Boccia RV, Croot CC, et al. Effects of enobosarm on muscle wasting and physical function in patients with cancer: a double-blind, randomised controlled phase 2 trial. Lancet Oncol 2013;14(4):335-45. PubMed
  5. Dalton JT, Barnette KG, Bohl CE, et al. The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double-blind, placebo-controlled phase II tri
  6. Coss CC, Jones A, Dalton JT. Pharmacokinetic drug interactions of the selective androgen receptor modulator GTx-024 (enobosarm) with itraconazole, rifampin, probenecid, celecoxib and rosuvastatin. Invest New Drugs 2016;34(4):458-67. PubMed
  7. FDA. FDA Warns against using SARMs in body building products. October 2017. Available at: https://www.fda.gov/newsevents/newsroom/fdainbrief/ucm583021.htm.
  8. Bedi H, Hammond C, Sanders D, Yang HM, Yoshida EM. Drug-induced liver injury from enobosarm (ostarine), a selective androgen receptor modulator. ACG Case Rep J 2021;8(1):e00518. PubMed
  9. Kintz P, Gheddar L, Paradis C, et al. Peroxisome Proliferator-Activated Receptor Delta Agonist (PPAR- d) and Selective Androgen Receptor Modulator (SARM) Abuse: Clinical, Analytical and Biological Data in a Case Involving a Poisonous Combination of GW1516
  10. Weinblatt D, Roy S. Drug-Induced Liver Injury Secondary to Enobosarm: A Selective Androgen Receptor Modulator. J Med Cases 2022;13(5):244-248. PubMed

See these in context on the Ostarine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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