Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

SARM S4 Andarine Ingredients & Drug Interactions

by DNA Anabolics

SARM S4 Andarine label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking SARM S4 Andarine against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

SARM S4 Andarine is a dietary supplement by DNA Anabolics with 1 active ingredient. Its ingredients are commonly taken for muscle building, strength gains, fat loss / body recomposition.Based on those ingredients, 9 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are S4. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against SARM S4 Andarine by DNA Anabolics

Ask about any prescription or over-the-counter medication and we check it for interactions with SARM S4 Andarine by DNA Anabolics — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of SARM S4 Andarine by DNA Anabolics

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: andarine (S4), a selective androgen receptor modulator—a research compound designed to bind to androgen receptors in muscle and bone. The capsule also contains rice flour, magnesium stearate, and gelatin as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Andarine product and its label doesn't state a use — see Andarine's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We hold no effectiveness data for andarine in our database. This is an experimental research compound, not an established dietary supplement, and its real-world benefits in humans have not been formally studied or documented.

The evidence, ingredient by ingredient Andarine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Andarine is an unapproved drug with unknown safety in humans and is not a legal supplement. The FDA has warned that selective androgen receptor modulators like andarine may increase the risk of heart attack and stroke.

Additionally, oral use could theoretically raise the risk of liver damage, though no thorough safety studies have been completed. A hormone-affecting drug like this must never be used during pregnancy.

It is also unsafe and unstudied during breastfeeding and should be avoided. Because andarine is experimental and unregulated, its true side-effect profile remains unclear.

Side effects, ingredient by ingredient Andarine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Andarine.
  • The most serious interaction on file is rated Moderate.
  • For scale: 9 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you use any androgens or androgen-type medications (such as testosterone products or anabolic steroids). Combining them with andarine may increase androgenic side effects.

Because andarine is unapproved and unregulated, your healthcare provider should review your full medication list.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Andarine is a research compound, not an approved medication or legal supplement. If you are considering it—especially alongside any androgen medications—talk with your doctor or pharmacist first.

They can discuss the documented risks (heart, stroke, liver) and help you make an informed choice. Do not use it during pregnancy or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 21, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about SARM S4 Andarine, straight from the product label.

Brand DNA Anabolics
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Sep 21, 2018
DSLD ID 181308
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for SARM S4 Andarine by DNA Anabolics, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
IngredientAmount% DV
S425 mg--

Other ingredients: Rice Flour, Magnesium Stearate, Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Disclaimer & Waiver of Liability The materials for sale are intended for laboratory and research use only. They are not for use as food additives, drugs, cosmetics, household chemicals or other inappropriate applications. You must be a minimum of 21 years of age or older to purchase this product. Not for human consumption

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

GMP Good Manufacturing Practice

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

SARM S4 Andarine by DNA Anabolics label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

SARM S4 Andarine label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in SARM S4 Andarine by DNA Anabolics

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

S4

Interacts with
9 drugs
25 mg per serving

Andarine (S-4) is a synthetic selective androgen receptor modulator (SARM) that is not approved by the FDA for human use and is banned in sports. It i...

S4 monograph & interactions

Other (inactive) ingredients: Rice Flour, Magnesium Stearate, Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

SARM S4 Andarine by DNA Anabolics Drug Interactions

Want to check YOUR meds against SARM S4 Andarine?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
9Drugs
9 Moderate

Ingredients driving the most interactions

S4 9

Individual Drug Interactions

The ingredients in SARM S4 Andarine interact with 9 drugs. Click any drug to see the details.

1 of the 1 ingredient in SARM S4 Andarine interact with drugs. Each result below shows which ingredient is responsible. S4

Each ingredient & the kinds of drugs it affects

For each ingredient in SARM S4 Andarine with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

S41 drug type · 9 drugs

Androgens

Due to its androgenic properties, Andarine (S-4) may theoretically interact with other androgenic drugs, potentially increasing the risk of side effects associated with androgenic activity (source: https://pubmed.ncbi.nlm.nih.gov/12604714/). These side effects can include masculinization, virilization, acne, hair loss, increased libido, aggression, mood changes, and liver toxicity.

Likelihood Possible Evidence C
S4 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for SARM S4 Andarine, from the product label.

DNA Anabolics

See all DNA Anabolics products
Name
DNA Anabolics
Pharmacist Counseling Corner

SARM S4 Andarine by DNA Anabolics: Common Questions

Does SARM S4 Andarine by DNA Anabolics interact with any medications?
Yes. Based on its ingredients, SARM S4 Andarine has a known interaction with 9 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
SARM S4 Andarine contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is andarine a legal supplement?
No. Andarine is an unapproved research compound, not a legal dietary supplement. The FDA does not regulate it as a supplement or medication.
Can I use this while pregnant or breastfeeding?
No. Andarine is unsafe during pregnancy because it affects hormones. It is also unsafe and unstudied during breastfeeding and should be avoided entirely in both situations.
What are the known risks of andarine?
The FDA has warned that it may increase the risk of heart attack and stroke. It could also potentially damage the liver. No thorough safety studies have been done in humans, so the full range of risks is unknown.
Does it work for building muscle?
We hold no effectiveness data for andarine in our database. While it was designed to target androgen receptors in muscle, its real-world benefits in humans have not been formally documented.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if SARM S4 Andarine is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

SARM S4 Andarine label
Go deeper

The Full Monographs Behind SARM S4 Andarine’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Andarine

Interacts with 9 drugs

Andarine (S-4) is a synthetic selective androgen receptor modulator (SARM) that is not approved by the FDA for human use and is banned in sports. It is not a legal dietary supplement ingredi...

Read the full Andarine monograph →
Sources

Sources & How We Checked

SARM S4 Andarine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Andarine 1 reference
  1. FDA. FDA Warns against using SARMs in body building products. October 2017. Available at: https://www.fda.gov/newsevents/newsroom/fdainbrief/ucm583021.htm.

See these in context on the Andarine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team