Interactions on record — worth a quick check against your medications. Based on 4 of 6 ingredients. Check your meds →
Dietary supplement

Six Flavor Teapills Ingredients & Drug Interactions

by Min Shan

Tablet Or Pill Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Six Flavor Teapills is a dietary supplement by Min Shan with 6 active ingredients. Its ingredients are commonly taken for kidney and adrenal support, anemia and blood building (traditional), inflammatory conditions.Based on those ingredients, 1,251 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Paeonia suffruticosa extract, Poria cocos sclerotium extract, Rehmannia glutinosa extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Six Flavor Teapills by Min Shan

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 6 active ingredients.
  • “Proprietary Extract Blend” is a proprietary blend — the label gives one combined amount (1,320 mg) without saying how much of each component you get.

Six Flavor Teapills contains six active ingredients, delivered as a proprietary extract blend. The active components are rehmannia, peony (Paeonia suffruticosa), poria mushroom, Dioscorea opposita, Alisma orientale, and Cornus officinalis extract.

The product also contains inactive ingredients — hydrated magnesium silicate, activated carbon, dextrin, and china wax — which serve as binders, flow agents, and capsule materials.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Chronic kidney disease (CKD) — rated "Possibly Effective" (Rehmannia) (Natural Medicines).

In our data, none of the six active ingredients in this formula have established effectiveness for the conditions they're traditionally used for. Rehmannia is possibly effective for chronic kidney disease, but it's rated insufficient evidence for diabetes, diabetic nephropathy, aplastic anemia, atopic disease, and osteoporosis.

Peony, poria mushroom, Dioscorea opposita, Alisma orientale, and Cornus officinalis are all rated insufficient evidence for their respective traditional uses — including aging skin, migraine, diabetes, diarrhea, and dementia. This means the evidence to prove they work for these purposes hasn't been established in the data we hold.

The evidence, ingredient by ingredient Rehmannia Peony Poria Mushroom American Dogwood

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Peony is possibly unsafe during pregnancy and should be avoided; rehmannia, poria mushroom, Dioscorea opposita, and Cornus officinalis don't have enough safety data for pregnancy, so they're best avoided as well. For breastfeeding, none of these ingredients have enough reliable data — it's safest to avoid the product while nursing.

While peony is generally well tolerated in short-term use, it can cause gastrointestinal side effects including nausea, diarrhea, abdominal distension, and loss of appetite in some people. Poria mushroom rarely causes allergic reactions like allergic rhinitis or asthma.

Human safety data for all ingredients in this formula are limited, and quality varies between products.

Side effects, ingredient by ingredient Rehmannia Peony Poria Mushroom American Dogwood

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 4 matched ingredients can interact with medications — Peony, Poria Mushroom, Rehmannia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 1,252 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs like warfarin or aspirin (Moderate risk of bleeding); blood pressure medication or diabetes drugs (Moderate risk of low blood pressure or low blood sugar); birth control pills or hormone replacement therapy (Moderate risk of reduced effectiveness or added side effects); any medication broken down by your liver, particularly those using CYP1A2 or CYP3A4 pathways (Moderate risk of drug buildup); clozapine for psychosis (Moderate risk of higher levels); phenytoin for seizures (Moderate risk of reduced effectiveness); sedatives or sleep aids (Moderate risk of increased drowsiness); or anticholinergic drugs for overactive bladder or Parkinson's disease or cholinergic drugs for myasthenia gravis (Moderate risk of interference).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This is a traditional Chinese herbal formula with limited human safety data and no established effectiveness in our database for any of its intended uses. If you take blood thinners, diabetes medication, blood pressure medication, birth control, or any drug broken down by your liver, or if you take sedatives or medications for myasthenia gravis or Alzheimer's disease, you need to check with your doctor or pharmacist before starting.

It's best to avoid this product during pregnancy or while breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 27, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Six Flavor Teapills, straight from the product label.

Brand Min Shan
Net contents 1.2 Ounce(s); 33 Gram(s); 200 Pill(s)
Market status On market
Date entered into DSLD Jul 27, 2021
DSLD ID 252184
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Six Flavor Teapills by Min Shan, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
8 Pill(s)
Maximum serving Sizes:
8 Pill(s)
Servings per container
25
IngredientAmount% DV
Proprietary Extract Blend1320 mg--
Rehmannia glutinosa extract0 NP--
Paeonia suffruticosa extract0 NP--
Poria cocos sclerotium extract0 NP--
Dioscorea opposita extract0 NP--
Alisma orientale extract0 NP--
Cornus officinalis extract0 NP--

Other ingredients: hydrated Magnesium Silicate, activated Carbon, Dextrin, China Wax

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

GMP

Min Shan Chinese herbal teapills have been produced at the Lanzhou Foci Pharmaceutical Co. Ltd. since 1929. Lanzhou Foci pioneered the manufacturing of extracted teapills, and are the genuine and original "Lanzhou Pills". Our domestic and internationally certified GMP factory and products have won numerous awards for quality and excellence. Each batch of Min Shan teapills has been tested for microbials, and other important quality parameters before leaving our facility to ensure quality and safety.

Foci Pharmaceutical Lanzhou Foci Pharmaceutical Co. Ltd. Lanzhou, Gansu Province, China

No artificial colors, flavors, refined sugar or pharmaceuticals

General Statements

Liu Wei Di Huang Wan

Visit www.fczy.com for more information.

US owned & operated since 1969

Internationally GMP certified manufacturer

Product of China

100% Natural Chinese herbs

FDA Statement of Identity

Herbal Dietary Supplement

Formula

Processed with rice wine (water rice, wheat)

Suggested/Recommended/Usage/Directions

Take 8 pills 3 times daily or as directed by your health care practitioner

Precautions

Keep out of reach of children

See for yourself

Six Flavor Teapills by Min Shan label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Six Flavor Teapills by Min Shan

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size8 Pill(s) Dosage formTablet Or Pill Servings per container25 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Extract Blend

1320 mg per serving

Other (inactive) ingredients: Hydrated Magnesium Silicate, Activated Carbon, Dextrin, China Wax. These complete the product’s ingredient list but are not active constituents.

Interaction report

Six Flavor Teapills by Min Shan Drug Interactions

Want to check YOUR meds against Six Flavor Teapills?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1,251Drugs
1,251 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Six Flavor Teapills with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Paeonia suffruticosa extract7 drug types · 811 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
In vitro research suggests that peony might have antiplatelet, anticoagulant, and antithrombotic effects.

Likelihood Possible Evidence D
Clozapine (Clozaril)

Theoretically, peony might increase the levels and clinical effects of clozapine.
In vitro research shows that peony suppresses the metabolism of clozapine via weak-to-moderate inhibitory effects on cytochromes P450 (CYP) 1A2 and CYP3A4. This effect has not been reported in humans.

Likelihood Possible Evidence D
Contraceptive Drugs

Theoretically, peony might interfere with contraceptive drugs due to competition for estrogen receptors.
In vitro and animal research shows that peony extract has estrogenic activity. Concomitant use might also increase the risk for estrogen-related adverse effects.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
In vitro research shows that peony suppresses the metabolism of clozapine via weak-to-moderate inhibitory effects on CYP1A2 and CYP3A4. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
In vitro research shows that peony suppresses the metabolism of clozapine via weak-to-moderate inhibitory effects on CYP1A2 and CYP3A4. This effect has not been reported in humans.

Likelihood Possible Evidence D
Estrogens

Theoretically, concomitant use of large amounts of peony might interfere with hormone replacement therapy and/or increase the risk for estrogen-related adverse effects.
In vitro and animal research shows that peony extract has estrogenic activity. Theoretically, peony might compete for estrogen receptors and/or cause additive estrogenic effects.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

Theoretically, peony might reduce the levels and clinical effects of phenytoin.
Animal research shows that taking peony root reduces levels of phenytoin. Some researchers suggest that peony root might affect cytochrome P450 (CYP) 2C9, which metabolizes phenytoin. However, preliminary research in humans shows that peony root does not alter levels of losartan (Cozaar), which is also metabolized by CYP2C9.

Likelihood Probable Evidence D

Poria cocos sclerotium extract3 drug types · 417 drugs

Anticholinergic Drugs

Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.

Likelihood Possible Evidence D
Cholinergic Drugs

Theoretically, poria mushroom might have additive effects when used with cholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Animal research shows that poria mushroom extract has sedative properties. This interaction has not been shown in humans.

Likelihood Possible Evidence D

Rehmannia glutinosa extract2 drug types · 258 drugs

Antidiabetes Drugs

Theoretically, rehmannia might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research shows that rehmannia may have hypoglycemic effects.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, rehmannia might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research shows that rehmannia may have hypotensive effects. Laboratory research shows that formulations of dried and processed rehmannia root inhibit angiotensin-converting enzyme (ACE).

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Six Flavor Teapills, from the product label.

Min Shan

See all Min Shan products
Name
Mayway Herbs
City
Oakland
State
CA
Phone Number
(800) 262-9929
Web Address
mayway.com
Pharmacist Counseling Corner

Six Flavor Teapills by Min Shan: Common Questions

Does Six Flavor Teapills by Min Shan interact with any medications?
Yes. Based on its ingredients, Six Flavor Teapills has a known interaction with 1,251 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Six Flavor Teapills contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm pregnant or breastfeeding?
No—peony is rated possibly unsafe in pregnancy and should be avoided, and the other four herb extracts don't have enough safety data for pregnancy either. For breastfeeding, none of these ingredients have reliable safety information, so it's best to avoid this product. Talk with your doctor or pharmacist about whether this formula is right for you.
What are the common side effects I might experience?
Peony may cause gastrointestinal upset—nausea, diarrhea, abdominal distension, and loss of appetite—in some people. Poria mushroom rarely causes allergic reactions like allergic rhinitis or asthma. Overall, human safety data for this formula are limited.
Does this product actually work for what it claims?
We don't have established evidence in our data that any of the six ingredients in this formula work for their traditional uses. Rehmannia shows possibly effective evidence only for chronic kidney disease; the rest are rated insufficient evidence. This doesn't mean they don't work, only that the evidence hasn't been proven yet in the studies we hold.
What is poria mushroom supposed to do?
Poria mushroom is traditionally used in Chinese medicine for several purposes, but we hold no established evidence that it works for any of them—including cancer, chronic fatigue, dementia, diabetes, or diarrhea. It's rated insufficient evidence for all these uses.
I saw that peony can cause bleeding problems. Should I avoid this product?
Peony may theoretically increase bleeding risk when combined with blood thinners or antiplatelet drugs like warfarin or aspirin. One case report documented an interaction with warfarin when a patient switched to a different herbal product containing peony. If you take any blood thinning medication, talk with your doctor or pharmacist before starting this formula.
Why can't you check all the ingredients for drug interactions?
We hold no interaction data for Dioscorea opposita or Alisma orientale—these ingredients haven't been studied in our database for how they might interact with medications. The other four ingredients we could check, and they do have documented interactions. For those two, you'll want to mention them by name when you discuss this product with your doctor or pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Six Flavor Teapills is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Six Flavor Teapills label
Sources

Sources & How We Checked

Six Flavor Teapills's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 22 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Rehmannia 3 references
  1. Zhang R, Zhou J, Jia Z, et al. Hypoglycemic effect of Rehmannia glutinosa oligosaccharide in hyperglycemic and alloxan-induced diabetic rats and its mechanism. J Ethnopharmacol 2004;90:39-43. PubMed
  2. Zhang RX, Li MX, Jia ZP. Rehmannia glutinosa: review of botany, chemistry and pharmacology. J Ethnopharmacol 2008;117(2):199-214. PubMed
  3. Chao CH, Hsu JL, Chen MF, et al. Anti-hypertensive effects of Radix Rehmanniae and its active ingredients. Nat Prod Res. 2020;34(11):1547-1552.

See these in context on the Rehmannia monograph →

Peony 15 references
  1. Chen LC, Chou MH, Lin MF, Yang LL. Effects of Paeoniae Radix, a traditional Chinese medicine, on the pharmacokinetics of phenytoin. J Clin Pharm Ther 2001;26:271-8. PubMed
  2. Guo TL, Zhou XW. [Clinical observations on the treatment of the gestational hypertension syndrome with Angelica and Paeonia powder]. Zhong Xi Yi Jie He Za Zhi 1986;6:714-6, 707.
  3. Xie HJ, Yasar U, Sandberg M, Rane A. Paeoniae Radix, a traditional Chinese medicine, and CYP2C9 activity. J Clin Pharm Ther 2002;27:229-30. . PubMed
  4. Harada M, Suzuki M, Ozaki Y. Effect of Japanese Angelica root and peony root on uterine contraction in the rabbit in situ. J Pharmacobiodyn 1984;7:304-11. PubMed
  5. Anon. Monograph. Peony (Paeonia spp). Alt Med Rev 2001;6:495-9.
  6. Bruynzeel DP. Contact Dermatitis Due to Paeonia (Peony). Contact Dermatitis 1989; 20:152-3..
  7. Bian, X., Xu, Y., Zhu, L., Gao, P., Liu, X., Liu, S., Qian, M., Gai, M., Yang, J., and Wu, Y. Prevention of maternal-fetal blood group incompatibility with traditional Chinese herbal medicine. Chin Med J (Engl.) 1998;111(7):585-587.
  8. Wong, A. L. and Chan, T. Y. Interaction between warfarin and the herbal product quilinggao. Ann Pharmacother 2003;37(6):836-838.
  9. Cai Y, Yuan Q, Xu K, et al. Assessment of the therapeutic effect of total glycosides of peony for juvenile idiopathic arthritis: a systematic review and meta-analysis. Evid Based Complement Alternat Med 2016;2016:8292486.
  10. Koo YK, Kim JM, Koo JY, et al. Platelet anti-aggregatory and blood anti-coagulant effects of compounds isolated from Paeonia lactiflora and Paeonia suffruticosa. Pharmazie 2010;65(8):624-8.
  11. Wang W, Tian DD, Zheng B, et al. Peony-glycyrrhiza decoction, an herbal preparation, inhibits clozapine metabolism via cytochrome P450s, but not flavin-containing monooxygenase in in vitro models. Drug Metab Dispos 2015;43(7):1147-53. PubMed
  12. Zhou Y, Jin L, Kong F, et al. Clinical and immunological consequences of total glucosides of paeony treatment in Sjögren's syndrome: A randomized controlled pilot trial. Int Immunopharmacol. 2016 Oct;39:314-319. doi: 10.1016/j.intimp.2016.08.006. PubMed
  13. Zhu Q, Qi X, Wu Y, Wang K. Clinical study of total glucosides of paeony for the treatment of diabetic kidney disease in patients with diabetes mellitus. Int Urol Nephrol. 2016 Nov;48(11):1873-1880. doi: 10.1007/s11255-016-1345-5. PubMed
  14. Xu Y, Li X, Chen T, et al. Radix Paeoniae Alba increases serum estrogen level and up-regulates estrogen receptor expression in uterus and vagina of immature/ovariectomized mice. Phytother Res. 2019;33(1):117-29. [RETRACTED].
  15. Liu X, Li X, Li X, et al. The efficacy and safety of total glucosides of peony in the treatment of primary Sjögren's syndrome: a multi-center, randomized, double-blinded, placebo-controlled clinical trial. Clin Rheumatol. 2019;38(3):657-64. Erratum i

See these in context on the Peony monograph →

Poria Mushroom 3 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Kim H, Park I, Park K, Park S, Kim YI, Park BG. The positive effects of Poria cocos extract on quality of sleep in insomnia rat models. Int J Environ Res Public Health 2022;19(11):6629. PubMed
  3. Lv Q, Di X, Bian B, Li K, Guo J. Neuroprotective effects of Poria cocos (Agaricomycetes) essential oil on Aß1-40-induced learning and memory deficit in rats. Int J Med Mushrooms 2022;24(10):73-82.

See these in context on the Poria Mushroom monograph →

American Dogwood 1 reference
  1. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source

See these in context on the American Dogwood monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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