Six Flavor Teapills Ingredients & Drug Interactions
by Min Shan
What is this page for?
First and foremost: checking Six Flavor Teapills against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Six Flavor Teapills is a dietary supplement by Min Shan with 6 active ingredients. Its ingredients are commonly taken for kidney and adrenal support, anemia and blood building (traditional), inflammatory conditions.Based on those ingredients, 1,251 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Paeonia suffruticosa extract, Poria cocos sclerotium extract, Rehmannia glutinosa extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Six Flavor Teapills by Min Shan
Ask about any prescription or over-the-counter medication and we check it for interactions with Six Flavor Teapills by Min Shan — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Six Flavor Teapills by Min Shan
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Six Flavor Teapills contains six active ingredients, delivered as a proprietary extract blend. The active components are rehmannia, peony (Paeonia suffruticosa), poria mushroom, Dioscorea opposita, Alisma orientale, and Cornus officinalis extract.
The product also contains inactive ingredients — hydrated magnesium silicate, activated carbon, dextrin, and china wax — which serve as binders, flow agents, and capsule materials.
Does it work?
Moderate evidence
In our data, none of the six active ingredients in this formula have established effectiveness for the conditions they're traditionally used for. Rehmannia is possibly effective for chronic kidney disease, but it's rated insufficient evidence for diabetes, diabetic nephropathy, aplastic anemia, atopic disease, and osteoporosis.
Peony, poria mushroom, Dioscorea opposita, Alisma orientale, and Cornus officinalis are all rated insufficient evidence for their respective traditional uses — including aging skin, migraine, diabetes, diarrhea, and dementia. This means the evidence to prove they work for these purposes hasn't been established in the data we hold.
How safe is it?
Well-documented data
Peony is possibly unsafe during pregnancy and should be avoided; rehmannia, poria mushroom, Dioscorea opposita, and Cornus officinalis don't have enough safety data for pregnancy, so they're best avoided as well. For breastfeeding, none of these ingredients have enough reliable data — it's safest to avoid the product while nursing.
While peony is generally well tolerated in short-term use, it can cause gastrointestinal side effects including nausea, diarrhea, abdominal distension, and loss of appetite in some people. Poria mushroom rarely causes allergic reactions like allergic rhinitis or asthma.
Human safety data for all ingredients in this formula are limited, and quality varies between products.
Meds to double-check
Moderate interaction found
Before taking this product, double-check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs like warfarin or aspirin (Moderate risk of bleeding); blood pressure medication or diabetes drugs (Moderate risk of low blood pressure or low blood sugar); birth control pills or hormone replacement therapy (Moderate risk of reduced effectiveness or added side effects); any medication broken down by your liver, particularly those using CYP1A2 or CYP3A4 pathways (Moderate risk of drug buildup); clozapine for psychosis (Moderate risk of higher levels); phenytoin for seizures (Moderate risk of reduced effectiveness); sedatives or sleep aids (Moderate risk of increased drowsiness); or anticholinergic drugs for overactive bladder or Parkinson's disease or cholinergic drugs for myasthenia gravis (Moderate risk of interference).
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
This is a traditional Chinese herbal formula with limited human safety data and no established effectiveness in our database for any of its intended uses. If you take blood thinners, diabetes medication, blood pressure medication, birth control, or any drug broken down by your liver, or if you take sedatives or medications for myasthenia gravis or Alzheimer's disease, you need to check with your doctor or pharmacist before starting.
It's best to avoid this product during pregnancy or while breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 27, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Six Flavor Teapills, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Six Flavor Teapills by Min Shan, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Extract Blend | 1320 mg | -- |
| Rehmannia glutinosa extract | 0 NP | -- |
| Paeonia suffruticosa extract | 0 NP | -- |
| Poria cocos sclerotium extract | 0 NP | -- |
| Dioscorea opposita extract | 0 NP | -- |
| Alisma orientale extract | 0 NP | -- |
| Cornus officinalis extract | 0 NP | -- |
Other ingredients: hydrated Magnesium Silicate, activated Carbon, Dextrin, China Wax
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
GMP
Min Shan Chinese herbal teapills have been produced at the Lanzhou Foci Pharmaceutical Co. Ltd. since 1929. Lanzhou Foci pioneered the manufacturing of extracted teapills, and are the genuine and original "Lanzhou Pills". Our domestic and internationally certified GMP factory and products have won numerous awards for quality and excellence. Each batch of Min Shan teapills has been tested for microbials, and other important quality parameters before leaving our facility to ensure quality and safety.
Foci Pharmaceutical Lanzhou Foci Pharmaceutical Co. Ltd. Lanzhou, Gansu Province, China
No artificial colors, flavors, refined sugar or pharmaceuticals
General Statements
Liu Wei Di Huang Wan
Visit www.fczy.com for more information.
US owned & operated since 1969
Internationally GMP certified manufacturer
Product of China
100% Natural Chinese herbs
FDA Statement of Identity
Herbal Dietary Supplement
Formula
Processed with rice wine (water rice, wheat)
Suggested/Recommended/Usage/Directions
Take 8 pills 3 times daily or as directed by your health care practitioner
Precautions
Keep out of reach of children
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Six Flavor Teapills by Min Shan label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Six Flavor Teapills by Min Shan
These are the 6 active ingredients this product is made of. Select any to open its full monograph.
Serving size8 Pill(s) Dosage formTablet Or Pill Servings per container25 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Extract Blend
- › Rehmannia glutinosa extract
- › Paeonia suffruticosa extract
- › Poria cocos sclerotium extract
- › Dioscorea opposita extract
- › Alisma orientale extract
- › Cornus officinalis extract
Other (inactive) ingredients: Hydrated Magnesium Silicate, Activated Carbon, Dextrin, China Wax. These complete the product’s ingredient list but are not active constituents.
Six Flavor Teapills by Min Shan Drug Interactions
HelloPharmacist Interaction Report
Six Flavor Teapills by Min Shan has documented interactions with medications through its rehmannia, peony, and poria mushroom extracts.
The most serious concern is a Moderate-severity risk of bleeding when peony is combined with blood thinners or antiplatelet drugs (like warfarin or aspirin), because peony may have anticoagulant effects.
Read the full breakdown — every affected drug type, severity by severity
Rehmannia carries Moderate-severity risks with blood pressure medications (which might drop too far) and diabetes drugs (which might lower blood sugar too much). Peony also interacts with several other drug types: medications broken down by your liver's CYP1A2 and CYP3A4 enzymes may build up to higher levels; hormone replacement therapy and birth control pills may be less effective or cause added estrogenic side effects; and the anti-psychotic clozapine levels may rise.
Additionally, peony may reduce how well the seizure medication phenytoin works. Poria mushroom extract theoretically may enhance sedatives, and it might interfere with anticholinergic drugs (used for overactive bladder, among other conditions) or add to the effects of cholinergic drugs (used in myasthenia gravis and Alzheimer's disease).
We could not check Dioscorea opposita or Alisma orientale for interactions because we hold no data for them. Altogether, these interactions span 1,252 individual medications.
Before you start this product, run your exact medications through the search tool on this page or talk with your doctor or pharmacist.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Six Flavor Teapills?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Six Flavor Teapills interact with 1,251 drugs. Click any drug to see the details.
3 of the 6 ingredients in Six Flavor Teapills interact with drugs. Each result below shows which ingredient is responsible. Paeonia suffruticosa extract Poria cocos sclerotium extract Rehmannia glutinosa extract
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Six Flavor Teapills — through 1 ingredient. Tap an ingredient for the detail:
Paeonia Suffruticosa ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Suffruticosa Extract + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Six Flavor Teapills — through 1 ingredient. Tap an ingredient for the detail:
Paeonia Suffruticosa ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Paeonia Suffruticosa Extract + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Six Flavor Teapills — through 1 ingredient. Tap an ingredient for the detail:
Paeonia Suffruticosa ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Suffruticosa Extract + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Six Flavor Teapills — through 1 ingredient. Tap an ingredient for the detail:
Paeonia Suffruticosa ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Suffruticosa Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Six Flavor Teapills — through 1 ingredient. Tap an ingredient for the detail:
Paeonia Suffruticosa ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Suffruticosa Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Six Flavor Teapills — through 1 ingredient. Tap an ingredient for the detail:
Paeonia Suffruticosa ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Paeonia Suffruticosa Extract + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Six Flavor Teapills — through 1 ingredient. Tap an ingredient for the detail:
Paeonia Suffruticosa ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Suffruticosa Extract + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Six Flavor Teapills — through 1 ingredient. Tap an ingredient for the detail:
Rehmannia Glutinosa ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, rehmannia might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Rehmannia Glutinosa Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Six Flavor Teapills — through 1 ingredient. Tap an ingredient for the detail:
Rehmannia Glutinosa ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, rehmannia might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Rehmannia Glutinosa Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Six Flavor Teapills — through 1 ingredient. Tap an ingredient for the detail:
Paeonia Suffruticosa ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Paeonia Suffruticosa Extract + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Six Flavor Teapills — through 1 ingredient. Tap an ingredient for the detail:
Poria Cocos Sclerotium ExtractCns Depressants, Anticholinergic Drugs Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Cocos Sclerotium Extract + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Six Flavor Teapills — through 1 ingredient. Tap an ingredient for the detail:
Paeonia Suffruticosa ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Suffruticosa Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Six Flavor Teapills — through 1 ingredient. Tap an ingredient for the detail:
Paeonia Suffruticosa ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Suffruticosa Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Six Flavor Teapills — through 1 ingredient. Tap an ingredient for the detail:
Paeonia Suffruticosa ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Paeonia Suffruticosa Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Six Flavor Teapills — through 1 ingredient. Tap an ingredient for the detail:
Paeonia Suffruticosa ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Suffruticosa Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Six Flavor Teapills — through 1 ingredient. Tap an ingredient for the detail:
Paeonia Suffruticosa ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Suffruticosa Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Six Flavor Teapills — through 1 ingredient. Tap an ingredient for the detail:
Paeonia Suffruticosa ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Suffruticosa Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Six Flavor Teapills — through 2 ingredients. Tap an ingredient for the detail:
Paeonia Suffruticosa ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Suffruticosa Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionPoria Cocos Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Six Flavor Teapills — through 2 ingredients. Tap an ingredient for the detail:
Paeonia Suffruticosa ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Suffruticosa Extract + Acetaminophen, Butalbital, Codeine interactionPoria Cocos Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Six Flavor Teapills — through 2 ingredients. Tap an ingredient for the detail:
Poria Cocos Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionPaeonia Suffruticosa ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Suffruticosa Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Six Flavor Teapills — through 2 ingredients. Tap an ingredient for the detail:
Paeonia Suffruticosa ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Suffruticosa Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionPoria Cocos Sclerotium ExtractAnticholinergic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Six Flavor Teapills — through 2 ingredients. Tap an ingredient for the detail:
Poria Cocos Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Caffeine, Codeine interactionPaeonia Suffruticosa ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Suffruticosa Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Six Flavor Teapills — through 2 ingredients. Tap an ingredient for the detail:
Paeonia Suffruticosa ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Suffruticosa Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionPoria Cocos Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Six Flavor Teapills — through 2 ingredients. Tap an ingredient for the detail:
Poria Cocos Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionPaeonia Suffruticosa ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Suffruticosa Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Six Flavor Teapills — through 1 ingredient. Tap an ingredient for the detail:
Paeonia Suffruticosa ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Suffruticosa Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Six Flavor Teapills — through 2 ingredients. Tap an ingredient for the detail:
Paeonia Suffruticosa ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Suffruticosa Extract + Acetaminophen, Caffeine, Pyrilamine interactionPoria Cocos Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Six Flavor Teapills — through 2 ingredients. Tap an ingredient for the detail:
Poria Cocos Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionPaeonia Suffruticosa ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Suffruticosa Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Six Flavor Teapills — through 2 ingredients. Tap an ingredient for the detail:
Poria Cocos Sclerotium ExtractAnticholinergic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionPaeonia Suffruticosa ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Suffruticosa Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Six Flavor Teapills — through 2 ingredients. Tap an ingredient for the detail:
Paeonia Suffruticosa ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Suffruticosa Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionPoria Cocos Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Six Flavor Teapills — through 2 ingredients. Tap an ingredient for the detail:
Poria Cocos Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionPaeonia Suffruticosa ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Suffruticosa Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Six Flavor Teapills with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Paeonia suffruticosa extract
Anticoagulant/Antiplatelet Drugs
Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
In vitro research suggests that peony might have antiplatelet, anticoagulant, and antithrombotic effects.
Clozapine (Clozaril)
Theoretically, peony might increase the levels and clinical effects of clozapine.
In vitro research shows that peony suppresses the metabolism of clozapine via weak-to-moderate inhibitory effects on cytochromes P450 (CYP) 1A2 and CYP3A4. This effect has not been reported in humans.
Contraceptive Drugs
Theoretically, peony might interfere with contraceptive drugs due to competition for estrogen receptors.
In vitro and animal research shows that peony extract has estrogenic activity. Concomitant use might also increase the risk for estrogen-related adverse effects.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
In vitro research shows that peony suppresses the metabolism of clozapine via weak-to-moderate inhibitory effects on CYP1A2 and CYP3A4. This effect has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
In vitro research shows that peony suppresses the metabolism of clozapine via weak-to-moderate inhibitory effects on CYP1A2 and CYP3A4. This effect has not been reported in humans.
Estrogens
Theoretically, concomitant use of large amounts of peony might interfere with hormone replacement therapy and/or increase the risk for estrogen-related adverse effects.
In vitro and animal research shows that peony extract has estrogenic activity. Theoretically, peony might compete for estrogen receptors and/or cause additive estrogenic effects.
Phenytoin (Dilantin)
Theoretically, peony might reduce the levels and clinical effects of phenytoin.
Animal research shows that taking peony root reduces levels of phenytoin. Some researchers suggest that peony root might affect cytochrome P450 (CYP) 2C9, which metabolizes phenytoin. However, preliminary research in humans shows that peony root does not alter levels of losartan (Cozaar), which is also metabolized by CYP2C9.
Poria cocos sclerotium extract
Anticholinergic Drugs
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.
Cholinergic Drugs
Theoretically, poria mushroom might have additive effects when used with cholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.
Cns Depressants
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Animal research shows that poria mushroom extract has sedative properties. This interaction has not been shown in humans.
Rehmannia glutinosa extract
Antidiabetes Drugs
Theoretically, rehmannia might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research shows that rehmannia may have hypoglycemic effects.
Antihypertensive Drugs
Theoretically, rehmannia might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research shows that rehmannia may have hypotensive effects. Laboratory research shows that formulations of dried and processed rehmannia root inhibit angiotensin-converting enzyme (ACE).
Brand information
Manufacturer and brand details for Six Flavor Teapills, from the product label.
Min Shan
See all Min Shan products- Name
- Mayway Herbs
- City
- Oakland
- State
- CA
- Phone Number
- (800) 262-9929
- Web Address
- mayway.com
Six Flavor Teapills by Min Shan: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Six Flavor Teapills’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Rehmannia
Interacts with 258 drugsRehmannia is a root used for centuries in Traditional Chinese Medicine, often to 'tonify' the kidneys and support energy or blood health. Human evidence for most modern uses is limited, so i...
Read the full Rehmannia monograph → Herb & supplement monographPeony
Interacts with 811 drugsPeony root is a traditional Chinese medicine herb often used for menstrual problems, cramps, and inflammation, frequently as part of combination formulas. Human evidence for most uses is lim...
Read the full Peony monograph → Herb & supplement monographPoria Mushroom
Interacts with 417 drugsPoria mushroom (Fu Ling) is a fungus long used in Traditional Chinese Medicine, mainly as a mild diuretic and digestive and calming aid. Modern scientific evidence in humans is very limited,...
Read the full Poria Mushroom monograph → Herb & supplement monographAmerican Dogwood
American Dogwood is a North American flowering tree whose bark was used in traditional folk medicine, especially as a substitute for quinine to treat fevers. There is very little modern huma...
Read the full American Dogwood monograph →Sources & How We Checked
Six Flavor Teapills's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 22 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Rehmannia 3 references
- Zhang R, Zhou J, Jia Z, et al. Hypoglycemic effect of Rehmannia glutinosa oligosaccharide in hyperglycemic and alloxan-induced diabetic rats and its mechanism. J Ethnopharmacol 2004;90:39-43. PubMed
- Zhang RX, Li MX, Jia ZP. Rehmannia glutinosa: review of botany, chemistry and pharmacology. J Ethnopharmacol 2008;117(2):199-214. PubMed
- Chao CH, Hsu JL, Chen MF, et al. Anti-hypertensive effects of Radix Rehmanniae and its active ingredients. Nat Prod Res. 2020;34(11):1547-1552.
Peony 15 references
- Chen LC, Chou MH, Lin MF, Yang LL. Effects of Paeoniae Radix, a traditional Chinese medicine, on the pharmacokinetics of phenytoin. J Clin Pharm Ther 2001;26:271-8. PubMed
- Guo TL, Zhou XW. [Clinical observations on the treatment of the gestational hypertension syndrome with Angelica and Paeonia powder]. Zhong Xi Yi Jie He Za Zhi 1986;6:714-6, 707.
- Xie HJ, Yasar U, Sandberg M, Rane A. Paeoniae Radix, a traditional Chinese medicine, and CYP2C9 activity. J Clin Pharm Ther 2002;27:229-30. . PubMed
- Harada M, Suzuki M, Ozaki Y. Effect of Japanese Angelica root and peony root on uterine contraction in the rabbit in situ. J Pharmacobiodyn 1984;7:304-11. PubMed
- Anon. Monograph. Peony (Paeonia spp). Alt Med Rev 2001;6:495-9.
- Bruynzeel DP. Contact Dermatitis Due to Paeonia (Peony). Contact Dermatitis 1989; 20:152-3..
- Bian, X., Xu, Y., Zhu, L., Gao, P., Liu, X., Liu, S., Qian, M., Gai, M., Yang, J., and Wu, Y. Prevention of maternal-fetal blood group incompatibility with traditional Chinese herbal medicine. Chin Med J (Engl.) 1998;111(7):585-587.
- Wong, A. L. and Chan, T. Y. Interaction between warfarin and the herbal product quilinggao. Ann Pharmacother 2003;37(6):836-838.
- Cai Y, Yuan Q, Xu K, et al. Assessment of the therapeutic effect of total glycosides of peony for juvenile idiopathic arthritis: a systematic review and meta-analysis. Evid Based Complement Alternat Med 2016;2016:8292486.
- Koo YK, Kim JM, Koo JY, et al. Platelet anti-aggregatory and blood anti-coagulant effects of compounds isolated from Paeonia lactiflora and Paeonia suffruticosa. Pharmazie 2010;65(8):624-8.
- Wang W, Tian DD, Zheng B, et al. Peony-glycyrrhiza decoction, an herbal preparation, inhibits clozapine metabolism via cytochrome P450s, but not flavin-containing monooxygenase in in vitro models. Drug Metab Dispos 2015;43(7):1147-53. PubMed
- Zhou Y, Jin L, Kong F, et al. Clinical and immunological consequences of total glucosides of paeony treatment in Sjögren's syndrome: A randomized controlled pilot trial. Int Immunopharmacol. 2016 Oct;39:314-319. doi: 10.1016/j.intimp.2016.08.006. PubMed
- Zhu Q, Qi X, Wu Y, Wang K. Clinical study of total glucosides of paeony for the treatment of diabetic kidney disease in patients with diabetes mellitus. Int Urol Nephrol. 2016 Nov;48(11):1873-1880. doi: 10.1007/s11255-016-1345-5. PubMed
- Xu Y, Li X, Chen T, et al. Radix Paeoniae Alba increases serum estrogen level and up-regulates estrogen receptor expression in uterus and vagina of immature/ovariectomized mice. Phytother Res. 2019;33(1):117-29. [RETRACTED].
- Liu X, Li X, Li X, et al. The efficacy and safety of total glucosides of peony in the treatment of primary Sjögren's syndrome: a multi-center, randomized, double-blinded, placebo-controlled clinical trial. Clin Rheumatol. 2019;38(3):657-64. Erratum i
Poria Mushroom 3 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Kim H, Park I, Park K, Park S, Kim YI, Park BG. The positive effects of Poria cocos extract on quality of sleep in insomnia rat models. Int J Environ Res Public Health 2022;19(11):6629. PubMed
- Lv Q, Di X, Bian B, Li K, Guo J. Neuroprotective effects of Poria cocos (Agaricomycetes) essential oil on Aß1-40-induced learning and memory deficit in rats. Int J Med Mushrooms 2022;24(10):73-82.
American Dogwood 1 reference
- Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC