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Dietary supplement

Stevia Leaves Powder Ingredients & Drug Interactions

by Bixa Botanical

Stevia Leaves Powder label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Stevia Leaves Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Stevia Leaves Powder is a dietary supplement by Bixa Botanical with 1 active ingredient. Its ingredients are commonly taken for sugar substitute / sweetener, blood sugar support in diabetes, weight management.Based on those ingredients, 259 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Stevia rebaudiana powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Stevia Leaves Powder by Bixa Botanical

Ask about any prescription or over-the-counter medication and we check it for interactions with Stevia Leaves Powder by Bixa Botanical — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Stevia Leaves Powder by Bixa Botanical

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product is pure Stevia rebaudiana powder — one active ingredient, a natural sweetener derived from stevia leaves. There are no inactive ingredients listed.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Stevia's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Helps maintain normal blood sugar and pressure levels.
  • We looked for evidence on: Diabetes, Hypertension.
  • The closest evidence on file: Stevia is rated "Insufficient Reliable Evidence To Rate" for Diabetes (Natural Medicines).
  • Also on file: Stevia is rated "Insufficient Reliable Evidence To Rate" for Hypertension.

The evidence for stevia isn't established in the data we hold. We have insufficient reliable evidence to rate it for diabetes, high blood pressure, or weight loss.

Some studies suggest stevia extract may lower blood glucose after meals in type 2 diabetes, but other research hasn't confirmed a consistent effect. If you're considering it for any of these purposes, chat with us about what the current research actually shows.

The evidence, ingredient by ingredient Stevia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Purified stevia sweeteners in typical food amounts are generally recognized as safe. However, this is a whole-leaf powder in supplement doses — the safety data on that form at higher amounts is limited, so use caution.

When people do take stevia, most side effects are mild and tend to go away after the first week: some report abdominal bloating, dizziness, headache, muscle pain, nausea, or numbness. Allergic reactions are rare but possible.

Side effects, ingredient by ingredient Stevia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Stevia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 259 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take lithium, blood pressure medications, or diabetes drugs, double-check with your pharmacist before starting this product. The interaction with lithium is the most serious — it could raise lithium levels.

Blood pressure and blood sugar effects are possible but less certain.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Stevia powder is generally well tolerated in short-term use and might be worth trying if you're looking for a plant-based sweetener. But if you take lithium, blood pressure medication, or diabetes drugs, you'll want to run this past your pharmacist first.

The safety data for supplement doses is thin, so it's not the best choice if you're pregnant, breastfeeding, or looking for a clinically proven treatment.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Stevia Leaves Powder, straight from the product label.

Brand Bixa Botanical
Barcode (UPC) 8904289001500
Net contents 200 Gram(s); 7 Ounce(s)
Market status On market
Date entered into DSLD Jul 23, 2020
DSLD ID 229703
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Stevia Leaves Powder by Bixa Botanical, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Gram(s)
Maximum serving Sizes:
3 Gram(s)
Servings per container
66
UPC/BARCODE
8904289001500
IngredientAmount% DV
Stevia rebaudiana powder3 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: Half - One teaspoon with warm water daily as required or as directed by your health practitioner.

Brand IP Statement(s)

Trademark of Bixa Botanical INC, USA

Formulation

Helps to maintain normal blood sugar & pressure levels.

Vegan

Non GMO

FDA Statement of Identity

Herbal Food Supplement

FDA Disclaimer Statement

Disclaimer: These statements have not been evaluated by the Food and Drug Administration and this product is a herbal food supplement and not intended to diagnose, treat, cure or prevent a disease.

Precautions

Warning: Consuming this product can expose you to chemicals including lead which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.p65warnings.ca.gov/food.

This product is not intended for use by those with serious medical condition or pregnant or lactating women.

Consult your physician before use.

Do not use if seal is broken.

Keep out of reach of children.

Storage

Store in a cool and dry place.

General Statements

Product of India

Over 140 years of quality trust

More than a company, Bixa Botanical is a dream - to share the collective knowledge of five generations of a family with the world; secrets of Herbal Healing that have been painstakingly accumulated over the last 140 years. Over 500 varieties of herbs are exclusively cleaned, processed and packed-in the company's ultra-modern in*house facilities.

Mfg. Lic. No : MP25D/14/318

Seals/Symbols

Good manufacturing practices GMP Certified K LBD (Kosher)

Formula

K LBD (Kosher)

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Stevia Leaves Powder by Bixa Botanical label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Stevia Leaves Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Stevia Leaves Powder by Bixa Botanical

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Gram(s) Dosage formPowder Servings per container66 Amounts shown are per serving.

Stevia rebaudiana powder

Interacts with
259 drugs
3 Gram(s) per serving

Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regu...

Stevia rebaudiana powder monograph & interactions
Interaction report

Stevia Leaves Powder by Bixa Botanical Drug Interactions

Want to check YOUR meds against Stevia Leaves Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
259Drugs
1 Moderate 258 Minor

Ingredients driving the most interactions

Stevia rebaudiana powder 259

Individual Drug Interactions

The ingredients in Stevia Leaves Powder interact with 259 drugs. Click any drug to see the details.

1 of the 1 ingredient in Stevia Leaves Powder interact with drugs. Each result below shows which ingredient is responsible. Stevia rebaudiana powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Stevia Leaves Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Stevia rebaudiana powder3 drug types · 259 drugs

Lithium

Theoretically, stevia might decrease clearance and increase levels of lithium.
Animal research suggests that stevia extracts might have diuretic activity. Theoretically, increased reabsorption of lithium along with sodium might reduce excretion and increase levels of lithium.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Preliminary clinical research in patients with type 2 diabetes suggests that taking a single dose of stevia extract 1000 mg reduces postprandial blood glucose levels when taken with a meal. However, other clinical research in patients with type 1 or type 2 diabetes suggests that taking stevioside 250 mg three times daily does not significantly affect blood glucose levels or glycated hemoglobin (HbA1C) after three months of treatment.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Stevia extract and stevioside might lower blood pressure in patients with hypertension. However, other clinical research suggests that stevioside does not significantly lower blood pressure in patients with hypertension.

Likelihood Possible Evidence D
Stevia rebaudiana powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Stevia Leaves Powder, from the product label.

Bixa Botanical

See all Bixa Botanical products
Name
Stelcore Management Service LLC
Street Address
8, Green Suite, #5766
City
Dover
State
Delaware
ZipCode
19901
Phone Number
+1281897875
Pharmacist Counseling Corner

Stevia Leaves Powder by Bixa Botanical: Common Questions

Does Stevia Leaves Powder by Bixa Botanical interact with any medications?
Yes. Based on its ingredients, Stevia Leaves Powder has a known interaction with 259 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Stevia Leaves Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will stevia help with my blood sugar or weight?
The evidence isn't solid enough for us to say whether it works. Some research suggests stevia extract may lower blood glucose briefly after meals in type 2 diabetes, but other studies haven't confirmed that. We don't have reliable evidence for weight loss either. Your doctor or pharmacist can discuss whether it's worth trying in your situation.
What side effects might I get?
Most people tolerate it well. Some report mild bloating, dizziness, headache, muscle pain, nausea, or numbness, especially in the first week — these usually fade. Allergic reactions are rare but possible.
Is this safer than other sweeteners?
Purified stevia sweeteners in food amounts are recognized as safe. This is a whole-leaf powder at supplement doses, though, and the safety data for that form at higher amounts is limited. So use caution if you're taking it regularly in large amounts.
Can I take this if I'm pregnant or breastfeeding?
The facts on file don't cover pregnancy and lactation safety for this ingredient. Talk with your pharmacist or doctor before using it if you're pregnant or nursing — they can give you personalized advice.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Stevia Leaves Powder is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Stevia Leaves Powder label
Go deeper

The Full Monographs Behind Stevia Leaves Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Stevia

Interacts with 259 drugs

Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regulators. Purified stevia extracts have a...

Read the full Stevia monograph →
Sources

Sources & How We Checked

Stevia Leaves Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Stevia 10 references
  1. Chan P, Xu DY, Liu JC, et al. The effect of stevioside on blood pressure and plasma catecholamines in spontaneously hypertensive rats. Life Sci 1998;63:1679-84. PubMed
  2. Melis MS. A crude extract of Stevia rebaudiana increases the renal plasma flow of normal and hypertensive rats. Braz J Med Biol Res 1996;29:669-75.
  3. Melis MS. Chronic administration of aqueous extract of Stevia rebaudiana in rats: renal effects. J Ethnopharmacol 1995;47:129-34. PubMed
  4. Melis MS, Sainati AR. Effect of calcium and verapamil on renal function of rats during treatment with stevioside. J Ethnopharmacol 1991;33:257-622. PubMed
  5. Hsieh MH, Chan P, Sue YM, et al. Efficacy and tolerability of oral stevioside in patients with mild essential hypertension: a two-year, randomized, placebo-controlled study. Clin Ther 2003;25:2797-808. PubMed
  6. Chan P, Tomlinson B, Chen YJ, et al. A double-blind placebo-controlled study of the effectiveness and tolerability of oral stevioside in human hypertension. Br J Clin Pharmacol 2000;50:215-20. PubMed
  7. Gregersen S, Jeppesen PB, Holst JJ, Hermansen K. Antihyperglycemic effects of stevioside in type 2 diabetic subjects. Metabolism 2004;53:73-6. PubMed
  8. Barriocanal LA, Palacios M, Benitez G, et al. Apparent lack of pharmacological effect of steviol glycosides used as sweeteners in humans. A pilot study of repeated exposures in some normotensive and hypotensive individuals and in Type 1 and Type 2 diabeti
  9. Ferri LA, Alves-Do-Prado W, Yamada SS, et al. Investigation of the antihypertensive effect of oral crude stevioside in patients with mild essential hypertension. Phytother Res 2006;20:732-6. PubMed
  10. Almiron-Roig E, Navas-Carretero S, Castelnuovo G, et al. Impact of acute consumption of beverages containing plant-based or alternative sweetener blends on postprandial appetite, food intake, metabolism, and gastro-intestinal symptoms: Results of the SWEE

See these in context on the Stevia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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