STR Concentrate Ingredients & Drug Interactions
by New Sun
What is this page for?
First and foremost: checking STR Concentrate against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
STR Concentrate is a dietary supplement by New Sun with 4 active ingredients. Its ingredients are commonly taken for sleep problems and insomnia, anxiety and restlessness, menopausal symptoms.Based on those ingredients, 960 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Chamomile, Hops, Skullcap. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against STR Concentrate by New Sun
Ask about any prescription or over-the-counter medication and we check it for interactions with STR Concentrate by New Sun — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of STR Concentrate by New Sun
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
STR Concentrate contains four active ingredients in a proprietary blend: hops, skullcap, chamomile, and catnip. Hops and skullcap are both traditionally used for relaxation and sleep support, though the evidence for these uses is not well established.
Chamomile and catnip have similar traditional roles in calming and digestive support. The product also contains several inactive ingredients—vegetarian capsule material, microcrystalline cellulose (a binder), rice flour, and magnesium stearate (a flow agent).
Does it work?
Not established
The evidence we hold does not establish that any ingredient in this product works for its intended uses. Hops, skullcap, catnip, and chamomile all carry ratings of insufficient reliable evidence for conditions like anxiety, insomnia, stress, and digestive upset.
That means studies either haven't been done, are too small, or are of poor quality — not that the ingredients don't work, but that we simply don't have solid proof they do.
How safe is it?
Well-documented data
Hops and skullcap are generally well tolerated in the short term but may cause drowsiness; long-term safety isn't well studied for either. The most common adverse effects of skullcap include cognitive impairment, digestive disturbances, and sedation — higher doses (around 200 mg or more) are more likely to cause these.
Hops can occasionally cause menstrual disturbances, and occupational exposure to hops dust is linked to chronic cough and bronchitis, though oral supplement use has not been studied for this risk. Catnip is likely fine for most adults in small amounts, but human safety data are limited.
Do not use this product during pregnancy — hops and catnip may interfere with hormones or stimulate the uterus, and safety data are insufficient for both pregnancy and breastfeeding across all ingredients. There isn't enough safety information on file for chamomile during pregnancy or breastfeeding either.
Meds to double-check
Moderate interaction found
Before you take this product, check with your pharmacist if you're on any sedative or sleep medications, anti-anxiety drugs, psychiatric medications like lithium, estrogen or hormone replacement therapy, or drugs that the liver metabolizes (your pharmacist can tell you if yours are in that group). The sedative ingredients here can pile on to prescription sedatives, and the lithium and hormone interactions need professional review.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
This product is designed for relaxation and sleep, but the evidence that it works isn't established. If you take any psychiatric, sedative, or blood pressure medications, or if you take lithium, talk to your pharmacist or doctor before starting — the sedative effects could add up, and the interactions with lithium and estrogens need a professional look.
If you're pregnant or breastfeeding, skip it. Use our medication checker to verify your specific drugs.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about STR Concentrate, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for STR Concentrate by New Sun, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 1000 mg | -- |
| Hops | 0 NP | -- |
| Skullcap | 0 NP | -- |
| Chamomile | 0 NP | -- |
| Catnip | 0 NP | -- |
Other ingredients: Vegetarian Capsule, Microcrystalline Cellulose, Rice Flour, Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Recommendation: As a dietary supplement, take two capsules with each meal. Two capsules can also be taken at bedtime.
Precautions
Do not use if safety seal is missing or broken.
Keep out of reach of children.
Warning: Do not take if you are pregnant. If you are nursing, taking any medications, or experiencing any health issues, consult your doctor before use.
Storage
Store in a cool, dry place.
Formulation
In today's fast-paced competitive world, many people have increased stress and difficulty coping with job responsibilities, competition, raising a family, and other responsibilities. STR helps to soothe those frayed nerves, excitability, and occasional restless nights. STR was formulated using herbs that have historically helped these problems, especially when combined in the proper amounts.
Mood support
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Herbal Supplement
Formula
Chamomile is mild but effective in helping to relax the nerves. It also helps mental alertness, menstrual cramps, and occasional upset stomach. Skullcap is a tonic and antispasmodic. Hops benefits the liver, spleen, glands, muscles, and helps clean the blood. It is known as a tonic herb in addition to being very calming. Catnip has been known for its calming and relaxing effect it can have on the body.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
STR Concentrate by New Sun label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in STR Concentrate by New Sun
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Vegetarian Capsule(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Other (inactive) ingredients: Vegetarian Capsule, Microcrystalline Cellulose, Rice Flour, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
STR Concentrate by New Sun Drug Interactions
HelloPharmacist Interaction Report
STR Concentrate by New Sun contains four ingredients, three of which interact with medications.
The most serious interaction involves hops and CNS depressants (sedatives, sleep aids, anxiety medications) — both hops and skullcap can cause additive sedation when combined with these drugs, a Moderate severity interaction. Catnip carries the same Moderate risk with CNS depressants.
Read the full breakdown — every affected drug type, severity by severity
Skullcap and hops both carry Minor interactions with drugs metabolized by the liver enzyme CYP3A4 (a broad category including certain statins, some blood pressure medications, and others), though the clinical significance may be small. Hops also interacts Moderately with estrogens and hormone replacement therapy — theoretically, large amounts of hops might interfere with how these hormones work, though most hops extracts contain very small amounts of the active constituents.
Catnip has a Moderate interaction with lithium, a psychiatric medication; catnip's diuretic properties might reduce how your body clears lithium, potentially raising its level.
We could not check chamomile for interactions — no data is on file for it. Altogether, these interactions span 853 individual medications.
Use the medication checker on this page to look up your exact prescriptions before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against STR Concentrate?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in STR Concentrate interact with 960 drugs. Click any drug to see the details.
4 of the 4 ingredients in STR Concentrate interact with drugs. Each result below shows which ingredient is responsible. Chamomile Hops Skullcap Catnip
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with STR Concentrate — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Ado-trastuzumab Emtansine interactionHopsCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hops extract might alter metabolism of CYP3A4 substrates; however, this effect may not be clinically significant.
Read the full Hops + Ado-trastuzumab Emtansine interactionAbemaciclibVerzenio
How Abemaciclib interacts with STR Concentrate — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Abemaciclib interactionHopsCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hops extract might alter metabolism of CYP3A4 substrates; however, this effect may not be clinically significant.
Read the full Hops + Abemaciclib interactionAbiraterone
How Abiraterone interacts with STR Concentrate — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Abiraterone interactionHopsCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hops extract might alter metabolism of CYP3A4 substrates; however, this effect may not be clinically significant.
Read the full Hops + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with STR Concentrate — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Abiraterone Acetate interactionHopsCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hops extract might alter metabolism of CYP3A4 substrates; however, this effect may not be clinically significant.
Read the full Hops + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with STR Concentrate — through 1 ingredient. Tap an ingredient for the detail:
ChamomileCytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP2C9 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with STR Concentrate — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acalabrutinib interactionHopsCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hops extract might alter metabolism of CYP3A4 substrates; however, this effect may not be clinically significant.
Read the full Hops + Acalabrutinib interactionAcepromazineAtravet
How Acepromazine interacts with STR Concentrate — through 4 ingredients. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Acepromazine interactionSkullcapCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Skullcap + Acepromazine interactionChamomileCns Depressants Moderate
Interaction Summary
Theoretically, German chamomile might have additive effects when used with CNS depressants.
Read the full Chamomile + Acepromazine interactionHopsCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of hops with sedative drugs might cause additive sedation.
Read the full Hops + Acepromazine interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with STR Concentrate — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Aspirin, Caffeine interactionHopsCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hops extract might alter metabolism of CYP3A4 substrates; however, this effect may not be clinically significant.
Read the full Hops + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with STR Concentrate — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Butalbital, Caffeine interactionHopsCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Hops extract does not seem to affect the metabolism of CYP1A2 substrates.
Read the full Hops + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with STR Concentrate — through 4 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Butalbital, Caffeine, Codeine interactionHopsCns Depressants, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use of hops with sedative drugs might cause additive sedation.
Read the full Hops + Acetaminophen, Butalbital, Caffeine, Codeine interactionCatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Acetaminophen, Butalbital, Caffeine, Codeine interactionSkullcapCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Skullcap + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with STR Concentrate — through 4 ingredients. Tap an ingredient for the detail:
SkullcapCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Skullcap + Acetaminophen, Butalbital, Codeine interactionChamomileCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP2D6 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Butalbital, Codeine interactionHopsCns Depressants, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of hops with sedative drugs might cause additive sedation.
Read the full Hops + Acetaminophen, Butalbital, Codeine interactionCatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with STR Concentrate — through 4 ingredients. Tap an ingredient for the detail:
ChamomileCns Depressants, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, German chamomile might have additive effects when used with CNS depressants.
Read the full Chamomile + Acetaminophen, Butalbital, Codeine Phosphate interactionSkullcapCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Skullcap + Acetaminophen, Butalbital, Codeine Phosphate interactionHopsCytochrome P450 1a2 (cyp1a2) Substrates, Cns Depressants Moderate
Interaction Summary
Hops extract does not seem to affect the metabolism of CYP1A2 substrates.
Read the full Hops + Acetaminophen, Butalbital, Codeine Phosphate interactionCatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with STR Concentrate — through 4 ingredients. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionSkullcapCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Skullcap + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionChamomileCns Depressants, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Theoretically, German chamomile might have additive effects when used with CNS depressants.
Read the full Chamomile + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionHopsCns Depressants, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use of hops with sedative drugs might cause additive sedation.
Read the full Hops + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with STR Concentrate — through 4 ingredients. Tap an ingredient for the detail:
HopsCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Hops extract does not seem to affect the metabolism of CYP1A2 substrates.
Read the full Hops + Acetaminophen, Caffeine, Codeine interactionChamomileCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants +2 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Caffeine, Codeine interactionSkullcapCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Skullcap + Acetaminophen, Caffeine, Codeine interactionCatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with STR Concentrate — through 4 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP2D6 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Caffeine, Codeine, Salicylamide interactionCatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Acetaminophen, Caffeine, Codeine, Salicylamide interactionHopsCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Hops extract does not seem to affect the metabolism of CYP1A2 substrates.
Read the full Hops + Acetaminophen, Caffeine, Codeine, Salicylamide interactionSkullcapCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Skullcap + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with STR Concentrate — through 4 ingredients. Tap an ingredient for the detail:
HopsCns Depressants, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use of hops with sedative drugs might cause additive sedation.
Read the full Hops + Acetaminophen, Caffeine, Dihydrocodeine interactionCatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Acetaminophen, Caffeine, Dihydrocodeine interactionChamomileCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP2D6 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Caffeine, Dihydrocodeine interactionSkullcapCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Skullcap + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with STR Concentrate — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Caffeine, Isometheptene interactionHopsCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hops extract might alter metabolism of CYP3A4 substrates; however, this effect may not be clinically significant.
Read the full Hops + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with STR Concentrate — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Caffeine, Pyrilamine interactionHopsCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hops extract might alter metabolism of CYP3A4 substrates; however, this effect may not be clinically significant.
Read the full Hops + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with STR Concentrate — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionHopsCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Hops extract does not seem to affect the metabolism of CYP1A2 substrates.
Read the full Hops + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with STR Concentrate — through 4 ingredients. Tap an ingredient for the detail:
HopsCytochrome P450 1a2 (cyp1a2) Substrates, Cns Depressants +1 Moderate
Interaction Summary
Hops extract does not seem to affect the metabolism of CYP1A2 substrates.
Read the full Hops + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionChamomileCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP2D6 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionCatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionSkullcapCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Skullcap + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with STR Concentrate — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionHopsCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hops extract might alter metabolism of CYP3A4 substrates; however, this effect may not be clinically significant.
Read the full Hops + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with STR Concentrate — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionHopsCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hops extract might alter metabolism of CYP3A4 substrates; however, this effect may not be clinically significant.
Read the full Hops + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with STR Concentrate — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP2D6 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionHopsCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Hops extract does not seem to affect the metabolism of CYP1A2 substrates.
Read the full Hops + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with STR Concentrate — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionHopsCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hops extract might alter metabolism of CYP3A4 substrates; however, this effect may not be clinically significant.
Read the full Hops + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with STR Concentrate — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionHopsCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hops extract might alter metabolism of CYP3A4 substrates; however, this effect may not be clinically significant.
Read the full Hops + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with STR Concentrate — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Chlorpheniramine, Phenylephrine interactionHopsCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hops extract might alter metabolism of CYP3A4 substrates; however, this effect may not be clinically significant.
Read the full Hops + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with STR Concentrate — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionHopsCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Hops extract does not seem to affect the metabolism of CYP1A2 substrates.
Read the full Hops + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with STR Concentrate — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionHopsCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hops extract might alter metabolism of CYP3A4 substrates; however, this effect may not be clinically significant.
Read the full Hops + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with STR Concentrate — through 4 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionHopsCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants +1 Moderate
Interaction Summary
Theoretically, hops extract might alter metabolism of CYP3A4 substrates; however, this effect may not be clinically significant.
Read the full Hops + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionCatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionSkullcapCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Skullcap + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with STR Concentrate — through 2 ingredients. Tap an ingredient for the detail:
ChamomileCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full Chamomile + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionHopsCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hops extract might alter metabolism of CYP3A4 substrates; however, this effect may not be clinically significant.
Read the full Hops + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in STR Concentrate with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Chamomile
Cns Depressants
Theoretically, German chamomile might have additive effects when used with CNS depressants.
German chamomile has mild sedative effects. Theoretically, concomitant use with drugs with sedative properties can cause additive effects and side effects.
Contraceptive Drugs
Theoretically, large amounts of German chamomile might reduce the effectiveness of oral contraceptives.
In vitro, German chamomile has demonstrated antiestrogenic activity. Theoretically, concomitant use of large amounts of German chamomile might interfere with contraceptive drugs through competition for estrogen receptors.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, German chamomile might inhibit CYP2C9 and increase levels of drugs metabolized by these enzymes.
In vitro evidence shows that German chamomile might inhibit CYP2C9. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP2C9 in patients taking German chamomile.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, German chamomile might inhibit CYP2D6 and increase levels of drugs metabolized by these enzymes.
In vitro evidence shows that German chamomile might inhibit CYP2D6. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP2D6 in patients taking German chamomile.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
In vitro evidence shows that German chamomile might inhibit CYP3A4. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP3A4 in patients taking German chamomile.
Estrogens
Theoretically, large amounts of German chamomile might reduce the effectiveness of estrogens.
In vitro, German chamomile has demonstrated antiestrogenic activity. Theoretically, large amounts of German chamomile might interfere with hormone replacement therapy through competition for estrogen receptors.
Tamoxifen (Nolvadex)
Theoretically, large amounts of German chamomile might interfere with the activity of tamoxifen.
In vitro, German chamomile has demonstrated antiestrogenic activity.
Warfarin (Coumadin)
German chamomile might increase the effects of warfarin and increase the risk of bleeding.
In one case, a 70-year-old female taking warfarin developed retroperitoneal hematoma and bilateral recti muscle bleeding along with an INR of 7.9 following ingestion of German chamomile tea 4-5 cups daily and use of a topical chamomile-based lotion applied 4-5 times daily.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
In vitro and animal research shows that German chamomile might inhibit CYP1A2. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP1A2 in patients taking German chamomile.
Hops
Cns Depressants
Theoretically, concomitant use of hops with sedative drugs might cause additive sedation.
Some animal research shows that hops has sedative effects.
Estrogens
Theoretically, concomitant use of large amounts of hops might interfere with hormone replacement therapy due to competition for estrogen receptors.
In vitro research suggests that certain hops constituents can competitively bind to estrogen receptors. However, most hops extracts contain very small amounts of these constituents.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Hops extract does not seem to affect the metabolism of CYP1A2 substrates.
In vitro research suggests that flavonoid constituents of hops inhibit CYP1A2 enzyme activity. However, a pharmacokinetic study in healthy postmenopausal patients shows that taking a standardized extract of spent hops containing prenylated phenols, as 59.5 mg twice daily for 2 weeks, does not affect levels of caffeine, a CYP1A2 probe substrate.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, hops extract might alter metabolism of CYP3A4 substrates; however, this effect may not be clinically significant.
Animal research suggests that specific constituents of hops, called lupulones, can induce hepatic CYP3A4 enzyme activity. However, a pharmacokinetic study in healthy postmenopausal patients with normal metabolism shows that taking a standardized extract of spent hops containing prenylated phenols, as 59.5 mg twice daily for 2 weeks, decreases the concentration of alprazolam, a CYP3A4 probe substrate, by 7.6%. This reduction is unlikely to be clinically relevant.
Skullcap
Cns Depressants
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Animal and clinical research suggests that skullcap can cause sedation and cognitive impairment.
Catnip
Cns Depressants
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Clinical and animal research shows that catnip has sedative properties.
Lithium
Theoretically, catnip might reduce excretion and increase levels of lithium.
Catnip is thought to have diuretic properties which might reduce lithium excretion. The dose of lithium might need to be decreased.
Brand information
Manufacturer and brand details for STR Concentrate, from the product label.
New Sun
See all New Sun products- Name
- New Sun, Inc.
- City
- Hendersonville
- State
- NC
- ZipCode
- 28792
- Phone Number
- (800) 544-0777
- Web Address
- mynewsun.com
STR Concentrate by New Sun: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind STR Concentrate’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Hops
Interacts with 863 drugsHops are most often used for sleep and mild anxiety, frequently combined with valerian, but the human evidence is limited and not very strong. They are generally well tolerated when used sho...
Read the full Hops monograph → Herb & supplement monographSkullcap
Interacts with 248 drugsAmerican skullcap is an herb traditionally used to calm anxiety and promote relaxation, but solid human evidence is very limited. It is generally considered relatively safe for short-term us...
Read the full Skullcap monograph → Herb & supplement monographGerman Chamomile
Interacts with 960 drugsGerman chamomile is a widely used herbal remedy taken mainly as a tea for calming, sleep, and digestive complaints. Early research suggests possible benefits for mild anxiety and some skin o...
Read the full German Chamomile monograph → Herb & supplement monographCatnip
Interacts with 248 drugsCatnip is a mint-family herb most often used as a calming tea for sleep, anxiety, and minor digestive upset, but solid human research supporting these uses is lacking. It is generally consid...
Read the full Catnip monograph →Sources & How We Checked
STR Concentrate's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Hops 15 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Zava DT, Dollbaum CM, Blen M. Estrogen and progestin bioactivity of foods, herbs, and spices. Proc Soc Exp Biol Med 1998;217:369-78. PubMed
- Milligan SR, Kalita JC, Heyerick A, et al. Identification of a potent phytoestrogen in hops (Humulus lupulus L.) and beer. J Clin Endocrinol Metab 1999;84:2249-52.. PubMed
- Milligan SR, Kalita JC, Pocock V, et al. The endocrine activities of 8-prenylnaringenin and related hop (Humulus lupulus L.) flavonoids. J Clin Endocrinol Metab 2000;85:4912-5.. DOI
- Henderson MC, Miranda CL, Stevens JF, et al. In vitro inhibition of human P450 enzymes by prenylated flavonoids from hops, Humulus lupulus. Xenobiotica 2000;30:235-51.. PubMed
- Mannering, G. J., Shoeman, J. A., and Deloria, L. B. Identification of the antibiotic hops component, colupulone, as an inducer of hepatic cytochrome P-4503A in the mouse. Drug Metab Dispos 1992;20(2):142-147. DOI
- Skorska, C., Mackiewicz, B., Gora, A., Golec, M., and Dutkiewicz, J. Health effects of inhalation exposure to organic dust in hops farmers. Ann.Univ Mariae.Curie Sklodowska [Med] 2003;58(1):459-465.
- Schiller, H., Forster, A., Vonhoff, C., Hegger, M., Biller, A., and Winterhoff, H. Sedating effects of Humulus lupulus L. extracts. Phytomedicine. 2006;13(8):535-541. PubMed
- van Hunsel, F. P. and Kampschoer, P. [Postmenopausal bleeding and dietary supplements: a possible causal relationship with hop- and soy-containing preparations]. Ned.Tijdschr.Geneeskd. 2012;156(41):A5095.
- Fenselau, C. and Talalay, P. Is oestrogenic activity present in hops? Food Cosmet.Toxicol. 1973;11(4):597-602. PubMed
- Godnic-Cvar, J., Zuskin, E., Mustajbegovic, J., Schachter, E. N., Kanceljak, B., Macan, J., Ilic, Z., and Ebling, Z. Respiratory and immunological findings in brewery workers. Am J Ind Med 1999;35(1):68-75. DOI
- Lee KM, Jung JS, Song DK, and et al. Effects of Humulus lupulus extract on the central nervous system in mice. Planta Med 1993;59(Suppl):A691.
- Assessment report on Humulus lupulus L., flos. European Medicines Agency, 2014. Available at: https://www.ema.europa.eu/en/documents/herbal-report/final-assessment-report-humulus-lupulus-l-flos_en.pdf. Accessed September 29, 2021.
- van Breemen RB, Chen L, Tonsing-Carter A, et al. Pharmacokinetic Interactions of a Hop Dietary Supplement with Drug Metabolism in Perimenopausal and Postmenopausal Women. J Agric Food Chem. 2020;68(18):5212-5220. PubMed
Skullcap 3 references
- Wolfson P, Hoffmann DL. An investigation into the efficacy of Scutellaria lateriflora in healthy volunteers. Altern Ther Health Med 2003;9:74-8.
- Awad, R., Arnason, J. T., Trudeau, V., Bergeron, C., Budzinski, J. W., Foster, B. C., and Merali, Z. Phytochemical and biological analysis of skullcap (Scutellaria lateriflora L.): a medicinal plant with anxiolytic properties. Phytomedicine. 2003;10(8):6 PubMed
- Brock C, Whitehouse J, Tewfik I, Towell T. American skullcap (Scutellaria lateriflora): a randomised, double-blind placebo-controlled crossover study of its effects on mood in healthy volunteers. Phytother Res 2014;28(5):692-8.
German Chamomile 15 references
- Subiza J, Subiza JL, Hinojosa M, et al. Anaphylactic reaction after the ingestion of chamomile tea; a study of cross-reactivity with other composite pollens. J Allergy Clin Immunol 1989;84:353-8. PubMed
- Budzinski JW, Foster BC, Vandenhoek S, Arnason JT. An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. Phytomedicine 2000;7:273-82. PubMed
- Viola H, Wasowski C, Levi de Stein M, et al. Apigenin, a component of Matricaria recutita flowers, is a central benzodiazepine receptors-ligand with anxiolytic effects. Planta Med 1995;61:213-6.
- van Ketel WG. Allergy to Matricaria chamomilla. Contact Dermatitis 1982;8:143. PubMed
- van Ketel WG. Allergy to Matricaria chamomilla. Contact Dermatitis 1987;16:50-1. PubMed
- Hormann HP, Korting HC. Evidence for the efficacy and safety of topical herbal drugs in dermatology: part I: anti-inflammatory agents. Phytomedicine 1994;1:161-71. PubMed
- Avallone R, Zanoli P, Puia G, et al. Pharmacological profile of apigenin, a flavonoid isolated from Matricaria chamomilla. Biochem Pharmacol 2000;59:1387-94. PubMed
- Kassi E, Papoutsi Z, Fokialakis N, et al. Greek plant extracts exhibit selective estrogen receptor modulator (SERM)-like properties. J Agric Food Chem 2004;52:6956-61. PubMed
- Maliakal PP, Wanwimolruk S. Effect of herbal teas on hepatic drug metabolizing enzymes in rats. J Pharm Pharmacol 2001;53:1323-9. PubMed
- Segal R, Pilote L. Warfarin interaction with Matricaria chamomilla. CMAJ 2006;174:1281-2. PubMed
- Loggia RD, Traversa U, Scarcia V, et al. Depressive effects of Chamomilla recutita (L.) Rausch, tubular flowers, on central nervous system in mice. Pharmacol Res Commun 1982;14(2):153-162. PubMed
- Ganzera M, Schneider P, Stuppner H. Inhibitory effects of the essential oil of chamomile (Matricaria recutita L.) and its major constituents on human cytochrome P450 enzymes. Life Sci 2006;78(8):856-861. PubMed
- Benito P, Rodríguez-Perez R, García F, Juste S, Moneo I, Caballero ML. Occupational allergic rhinoconjunctivitis induced by Matricaria chamomilla with tolerance of chamomile tea. J Investig Allergol Clin Immunol. 2014;24(5):369-70. No abstract available.
- Braga FT, Santos AC, Bueno PC, et al. Use of Chamomilla recutita in the prevention and treatment of oral mucositis in patients undergoing hematopoietic stem cell transplantation: a randomized, controlled, phase II clinical trial. Cancer Nurs 2015;38(4):32 PubMed
- Sarris J, Ravindran A, Yatham LN, et al. Clinician guidelines for the treatment of psychiatric disorders with nutraceuticals and phytoceuticals: The World Federation of Societies of Biological Psychiatry (WFSBP) and Canadian Network for Mood and Anxiety T
Catnip 7 references
- Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Osterhoudt KC, Lee SK, Callahan JM, Henretig FM. Catnip and the alteration of human consciousness. Vet Hum Toxicol 1997;39:373-5.
- Sherry, C. J. and Hunter, P. S. The effect of an ethanol extract of catnip (Nepeta cataria) on the behavior of the young chick. Experientia 2-15-1979;35(2):237-238. PubMed
- Harney, J. W., Barofsky, I. M., and Leary, J. D. Behavioral and toxicological studies of cyclopentanoid monoterpenes from Nepeta cataria. Lloydia. 1978;41(4):367-374.
- Massoco, C. O., Silva, M. R., Gorniak, S. L., Spinosa, M. S., and Bernardi, M. M. Behavioral effects of acute and long-term administration of catnip (Nepeta cataria) in mice. Vet.Hum.Toxicol 1995;37(6):530-533.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC