Advanced BP Ingredients & Drug Interactions
by New Sun
What is this page for?
First and foremost: checking Advanced BP against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Advanced BP is a dietary supplement by New Sun with 15 active ingredients. Its ingredients are commonly taken for heart failure symptoms, high blood pressure, chest pain (angina).Based on those ingredients, 1,462 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Passionflower, Celery, Gota Kola. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Advanced BP by New Sun
Ask about any prescription or over-the-counter medication and we check it for interactions with Advanced BP by New Sun — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Advanced BP by New Sun
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Advanced BP contains 15 ingredients in a proprietary blend, including hawthorn, passionflower, European mistletoe, honeysuckle, chrysanthemum, tribulus, celery, gotu kola, oats, and rosemary. Hawthorn is included for heart health and blood pressure support; passionflower for its calming properties; and tribulus traditionally for blood pressure and blood sugar.
Oats are well-studied for heart health and cholesterol support. The product also contains inactive ingredients—a vegetarian capsule that holds the blend together.
Does it work?
Strong evidence
Evidence is limited for most of the ingredients in this blend when it comes to blood pressure specifically. Hawthorn, tribulus, celery, and European mistletoe all show insufficient evidence or mixed findings for the conditions listed in the product facts.
Oats stand out as likely effective for heart health and cholesterol—they have robust evidence for lowering cholesterol and supporting coronary heart disease prevention. Gotu kola shows possibly effective evidence for venous insufficiency (leg swelling).
Passionflower is possibly effective for insomnia and pre-procedural anxiety, though it's not marketed here for those uses. For most other ingredients and uses on file, the evidence is insufficient to rate their effectiveness.
How safe is it?
Well-documented data
Most ingredients are generally well tolerated in short-term use, though several carry cautions. Hawthorn is generally well tolerated but requires medical supervision if you have a heart condition—it can affect heart rate and rhythm.
Passionflower commonly causes drowsiness, dizziness, and confusion; it should not be mixed with sedatives or alcohol. European mistletoe is potentially toxic in raw form and should only be used as a standardized product under medical guidance.
Celery seed may trigger allergic reactions, including anaphylaxis in very sensitive people. Several ingredients—passionflower, honeysuckle, and tribulus—carry rare reports of serious side effects including heart rhythm problems and organ damage at high doses or with prolonged use.
Chrysanthemum can cause allergic reactions, and an estimated 60% of Europeans are allergic to it. Gotu kola has rare reports of liver damage, though this was not seen in clinical trials at typical doses.
Meds to double-check
Major interaction found
Before taking Advanced BP, have your pharmacist check these medication types: nitrates and phosphodiesterase-5 inhibitors (Major risk of low blood pressure), beta-blockers, calcium channel blockers, antihypertensive drugs, anticoagulants and antiplatelet drugs, antidiabetes drugs and insulin, lithium, CNS depressants, and aspirin or salicylate-containing pain relievers. Passionflower may cause additive drowsiness with sedatives.
Celery interacts with several other drugs including levothyroxine and venlafaxine. Run your complete medication list through the checker on this page.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with strong clinical evidence behind its ingredients' uses. Major medication interactions have been identified, and safety information is well characterized.
This product combines multiple blood-pressure-focused herbs, but it carries substantial interaction risks—especially with heart medications, blood thinners, and diabetes drugs. If you take any prescription medications, particularly for blood pressure, heart rhythm, blood clotting, blood sugar, or mood, check your exact drugs with the tool on this page before starting.
Anyone with a diagnosed heart condition should talk to their doctor first; passionflower users should expect drowsiness and avoid driving. This is not a substitute for medical treatment of high blood pressure.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 11 of 15 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 28, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Advanced BP, straight from the product label.
| Brand | New Sun |
|---|---|
| Barcode (UPC) | 51-2 |
| Net contents | 90 Vegetarian Capsules |
| Market status | On market |
| Date entered into DSLD | May 28, 2019 |
| DSLD ID | 202033 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Advanced BP by New Sun, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 1230 mg | -- |
| Hawthorn | 0 NP | -- |
| Passionflower | 0 NP | -- |
| European Mistletoe | 0 NP | -- |
| Honeysuckle | 0 NP | -- |
| Feather Cockscomb | 0 NP | -- |
| Eucommia (bark) concentrate | 0 NP | -- |
| Chrysanthemum | 0 NP | -- |
| Sickle-Pod Senna (seed) concentrate | 0 NP | -- |
| Tribulus | 0 NP | -- |
| Heal All (fruit) concentrate | 0 NP | -- |
| Wild Chrysanthemum (flower) concentrate | 0 NP | -- |
| Celery | 0 NP | -- |
| Gota Kola | 0 NP | -- |
| Oat | 0 NP | -- |
| Rosemary | 0 NP | -- |
Other ingredients: Vegetarian Capsule
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Recommendation: As a dietary supplement, take two capsules three times daily, preferably with meals.
Precautions
Keep out of reach of children.
Do not use if safety seal is missing or broken.
Warning: Individuals with renal disorders should use with caution. Do not take if you suffer from protein hypersensitivity or progressive infections such as tuberculosis and AIDS. Do not use this product if you have abdominal pain or diarrhea. Discontinue use in the event of diarrhea or watery stools.
If you are pregnant, nursing, taking any medications, or experiencing health issues, consult your doctor before use.
Anyone under the age of 18 should consult a physician concerning usage and dosage of this product.
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
General Statements
Herbal
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Advanced BP by New Sun label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Advanced BP by New Sun
These are the 15 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Vegetarian Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
- › Hawthorn
- › Passionflower
- › European Mistletoe
- › Honeysuckle
- › Feather Cockscomb
- › Eucommia (bark) concentrate
- › Chrysanthemum
- › Sickle-Pod Senna (seed) concentrate
- › Tribulus
- › Heal All (fruit) concentrate
- › Wild Chrysanthemum (flower) concentrate
- › Celery
- › Gota Kola
- › Oat
- › Rosemary
Other (inactive) ingredients: Vegetarian Capsule. These complete the product’s ingredient list but are not active constituents.
Advanced BP by New Sun Drug Interactions
HelloPharmacist Interaction Report
Advanced BP by New Sun contains multiple ingredients with documented interactions with medications.
The most serious concerns involve hawthorn, which carries Major-severity interactions with nitrates (used for chest pain) and phosphodiesterase-5 inhibitors like sildenafil (Viagra). Both can cause dangerous drops in blood pressure when combined with hawthorn's blood-pressure-lowering effects.
Read the full breakdown — every affected drug type, severity by severity
Several ingredients interact with blood pressure medications. Hawthorn, tribulus, celery, and European mistletoe all may lower blood pressure further, raising the risk of hypotension (dangerously low blood pressure).
Hawthorn and celery can also interact with beta-blockers and calcium channel blockers—common heart drugs—by adding to their effects on blood pressure and heart function. Tribulus carries a separate Moderate concern with lithium (a mood stabilizer), potentially increasing lithium levels to unsafe ranges.
Other notable interactions: hawthorn and honeysuckle with blood thinners (anticoagulants and antiplatelet drugs like warfarin or clopidogrel) may raise bleeding risk. Passionflower may add to the drowsiness caused by sedatives and sleeping pills.
Celery and oats interact with diabetes medications and insulin, potentially lowering blood sugar too much. Rosemary may increase bleeding risk with blood thinners and add to the effects of aspirin and similar pain relievers.
We could not check several ingredients—feather cockscomb, eucommia bark concentrate, sickle-pod senna seed concentrate, and heal all fruit concentrate—because we hold no data for them.
Altogether, these interactions span 1,441 individual medications. Use the medication checker on this page to verify your exact prescriptions before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Advanced BP?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Advanced BP interact with 1,462 drugs. Click any drug to see the details.
9 of the 15 ingredients in Advanced BP interact with drugs. Each result below shows which ingredient is responsible. Passionflower Celery Gota Kola Rosemary European Mistletoe Tribulus Hawthorn Honeysuckle Oat
AvanafilStendra
How Avanafil interacts with Advanced BP — through 2 ingredients. Tap an ingredient for the detail:
HawthornPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn + Avanafil interactionPassionflowerCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower + Avanafil interactionFinasteride, TadalafilEntadfi
How Finasteride, Tadalafil interacts with Advanced BP — through 2 ingredients. Tap an ingredient for the detail:
HawthornPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn + Finasteride, Tadalafil interactionPassionflowerCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower + Finasteride, Tadalafil interactionGlyceryl TrinitrateNitronal
How Glyceryl Trinitrate interacts with Advanced BP — through 1 ingredient. Tap an ingredient for the detail:
HawthornNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn + Glyceryl Trinitrate interactionIsosorbide DinitrateAngitak, Cedocard Retard, Isoket, Isoket Retard, Isordil
How Isosorbide Dinitrate interacts with Advanced BP — through 1 ingredient. Tap an ingredient for the detail:
HawthornNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn + Isosorbide Dinitrate interactionIsosorbide Dinitrate, HydralazineBiDil
How Isosorbide Dinitrate, Hydralazine interacts with Advanced BP — through 4 ingredients. Tap an ingredient for the detail:
HawthornNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn + Isosorbide Dinitrate, Hydralazine interactionTribulusAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking tribulus with antihypertensive drugs might increase the risk of hypotension.
Read the full Tribulus + Isosorbide Dinitrate, Hydralazine interactionEuropean MistletoeAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, European mistletoe might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full European Mistletoe + Isosorbide Dinitrate, Hydralazine interactionCeleryAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, celery seed extract might have additive effects with antihypertensive drugs.
Read the full Celery + Isosorbide Dinitrate, Hydralazine interactionIsosorbide MononitrateAngeze, Angeze SR, Chemydur 60XL, Dynamin, Elantan, Elantan LA +13 more
How Isosorbide Mononitrate interacts with Advanced BP — through 1 ingredient. Tap an ingredient for the detail:
HawthornNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn + Isosorbide Mononitrate interactionMacitentan, TadalafilOpsynvi
How Macitentan, Tadalafil interacts with Advanced BP — through 6 ingredients. Tap an ingredient for the detail:
HawthornPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn + Macitentan, Tadalafil interactionCeleryAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, celery seed extract might have additive effects with antihypertensive drugs.
Read the full Celery + Macitentan, Tadalafil interactionEuropean MistletoeAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, European mistletoe might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full European Mistletoe + Macitentan, Tadalafil interactionGota KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gota Kola + Macitentan, Tadalafil interactionTribulusAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking tribulus with antihypertensive drugs might increase the risk of hypotension.
Read the full Tribulus + Macitentan, Tadalafil interactionPassionflowerCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower + Macitentan, Tadalafil interactionNicorandilAprior, Dancor, Ikorel, Sigmart, Zynicor
How Nicorandil interacts with Advanced BP — through 1 ingredient. Tap an ingredient for the detail:
HawthornNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn + Nicorandil interactionNitroglycerinGonitro, Nitro Time, Nitro-Bid, Nitrocine Timecaps, Nitrogard, Nitrogard SR +7 more
How Nitroglycerin interacts with Advanced BP — through 1 ingredient. Tap an ingredient for the detail:
HawthornNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn + Nitroglycerin interactionPentaerythritol TetranitratePeritrate, Peritrate SA
How Pentaerythritol Tetranitrate interacts with Advanced BP — through 1 ingredient. Tap an ingredient for the detail:
HawthornNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn + Pentaerythritol Tetranitrate interactionSildenafilRevatio
How Sildenafil interacts with Advanced BP — through 2 ingredients. Tap an ingredient for the detail:
HawthornPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn + Sildenafil interactionPassionflowerCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower + Sildenafil interactionSildenafil CitrateViagra
How Sildenafil Citrate interacts with Advanced BP — through 2 ingredients. Tap an ingredient for the detail:
HawthornPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn + Sildenafil Citrate interactionPassionflowerCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower + Sildenafil Citrate interactionTadalafilCialis, Tadliq
How Tadalafil interacts with Advanced BP — through 2 ingredients. Tap an ingredient for the detail:
HawthornPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn + Tadalafil interactionPassionflowerCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower + Tadalafil interactionVardenafilLevitra, Staxyn
How Vardenafil interacts with Advanced BP — through 2 ingredients. Tap an ingredient for the detail:
HawthornPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn + Vardenafil interactionPassionflowerCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower + Vardenafil interaction6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Advanced BP — through 2 ingredients. Tap an ingredient for the detail:
European MistletoeImmunosuppressants Moderate
Interaction Summary
Theoretically, European mistletoe might decrease the effectiveness of immunosuppressants.
Read the full European Mistletoe + 6-mercaptopurine interactionGota KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gota Kola + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Advanced BP — through 1 ingredient. Tap an ingredient for the detail:
Gota KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gota Kola + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Advanced BP — through 1 ingredient. Tap an ingredient for the detail:
Gota KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gota Kola + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Advanced BP — through 4 ingredients. Tap an ingredient for the detail:
CeleryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, celery root might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Celery + Abciximab interactionHoneysuckleAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, honeysuckle might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Honeysuckle + Abciximab interactionRosemaryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Rosemary + Abciximab interactionHawthornAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn + Abciximab interactionAbiraterone
How Abiraterone interacts with Advanced BP — through 2 ingredients. Tap an ingredient for the detail:
Gota KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gota Kola + Abiraterone interactionPassionflowerCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Advanced BP — through 2 ingredients. Tap an ingredient for the detail:
Gota KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gota Kola + Abiraterone Acetate interactionPassionflowerCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Advanced BP — through 5 ingredients. Tap an ingredient for the detail:
HawthornAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn + Abrocitinib interactionHoneysuckleAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, honeysuckle might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Honeysuckle + Abrocitinib interactionRosemaryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Rosemary + Abrocitinib interactionCeleryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, celery root might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Celery + Abrocitinib interactionEuropean MistletoeImmunosuppressants Moderate
Interaction Summary
Theoretically, European mistletoe might decrease the effectiveness of immunosuppressants.
Read the full European Mistletoe + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Advanced BP — through 4 ingredients. Tap an ingredient for the detail:
OatAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oats may have additive effects with antidiabetic agents and might increase the risk of hypoglycemia.
Read the full Oat + Acarbose interactionRosemaryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking rosemary with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Rosemary + Acarbose interactionTribulusAntidiabetes Drugs Moderate
Interaction Summary
Taking tribulus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Tribulus + Acarbose interactionGota KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gota Kola + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Advanced BP — through 5 ingredients. Tap an ingredient for the detail:
Gota KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gota Kola + Acebutolol interactionTribulusAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking tribulus with antihypertensive drugs might increase the risk of hypotension.
Read the full Tribulus + Acebutolol interactionHawthornBeta-blockers Moderate
Interaction Summary
Theoretically, concomitant use might cause additive effects on blood pressure and heart rate.
Read the full Hawthorn + Acebutolol interactionEuropean MistletoeAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, European mistletoe might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full European Mistletoe + Acebutolol interactionCeleryAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, celery seed extract might have additive effects with antihypertensive drugs.
Read the full Celery + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Advanced BP — through 4 ingredients. Tap an ingredient for the detail:
CeleryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, celery root might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Celery + Acenocoumarol interactionHoneysuckleAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, honeysuckle might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Honeysuckle + Acenocoumarol interactionHawthornAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn + Acenocoumarol interactionRosemaryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Rosemary + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Advanced BP — through 3 ingredients. Tap an ingredient for the detail:
Gota KolaCns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
Read the full Gota Kola + Acepromazine interactionPassionflowerCns Depressants Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower + Acepromazine interactionCeleryPhotosensitizing Drugs Minor
Interaction Summary
Theoretically, celery might increase the risk of photosensitivity reactions when taken with photosensitizing drugs.
Read the full Celery + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Advanced BP — through 3 ingredients. Tap an ingredient for the detail:
CeleryCytochrome P450 1a2 (cyp1a2) Substrates, Acetaminophen (tylenol, Others) Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery + Acetaminophen interactionGota KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gota Kola + Acetaminophen interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Advanced BP — through 5 ingredients. Tap an ingredient for the detail:
Gota KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gota Kola + Acetaminophen, Aspirin interactionHoneysuckleAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, honeysuckle might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Honeysuckle + Acetaminophen, Aspirin interactionHawthornAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn + Acetaminophen, Aspirin interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Aspirin interactionCeleryCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Advanced BP — through 6 ingredients. Tap an ingredient for the detail:
CeleryAnticoagulant/antiplatelet Drugs, Acetaminophen (tylenol, Others) +1 Moderate
Interaction Summary
Theoretically, celery root might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Celery + Acetaminophen, Aspirin, Caffeine interactionRosemaryAspirin, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, rosemary might have additive effects with salicylate-containing drugs such as aspirin.
Read the full Rosemary + Acetaminophen, Aspirin, Caffeine interactionGota KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gota Kola + Acetaminophen, Aspirin, Caffeine interactionHoneysuckleAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, honeysuckle might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Honeysuckle + Acetaminophen, Aspirin, Caffeine interactionHawthornAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn + Acetaminophen, Aspirin, Caffeine interactionPassionflowerCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Advanced BP — through 3 ingredients. Tap an ingredient for the detail:
CeleryCytochrome P450 1a2 (cyp1a2) Substrates, Photosensitizing Drugs +1 Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionGota KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gota Kola + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Advanced BP — through 3 ingredients. Tap an ingredient for the detail:
Gota KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gota Kola + Acetaminophen, Butalbital interactionCeleryCytochrome P450 1a2 (cyp1a2) Substrates, Acetaminophen (tylenol, Others) Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery + Acetaminophen, Butalbital interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Butalbital interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Advanced BP with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Passionflower
Cns Depressants
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Research in animals and humans shows that passion flower has sedative effects which can be additive when used with sedative medications like lorazepam.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
In vitro research suggests that passion flower can induce CYP3A4 enzymes, albeit to a much lower degree than rifampin, a known CYP3A4 inducer.
Organic Anion-Transporting Polypeptide Substrates (Oatp)
Theoretically, passion flower might reduce the bioavailability of OATP2B1 and OATP1A2 substrates.
In vitro research shows that the passion flower constituents apigenin and vitexin inhibit OATP2B1 and OATP1A2. This inhibition may be dose-dependent. One specific high-flavonoid passion flower extract (Valverde) seems to inhibit OATP2B1 and OATP1A2, while another extract with a lower flavonoid concentration (Arkocaps) shows less potent inhibition. OATPs are responsible for the uptake of drugs and other compounds into the body; however, the specific activities of OATP2B1 and OATP1A2 are not well characterized.
Celery
Anticoagulant/Antiplatelet Drugs
Theoretically, celery root might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Celery root contains the constituents falcarinol and falcarindiol. Laboratory research suggests that these constituents can inhibit platelet aggregation. This effect has not been reported in humans.
Antihypertensive Drugs
Theoretically, celery seed extract might have additive effects with antihypertensive drugs.
Clinical research suggests that taking celery seed extract may reduce daytime systolic blood pressure by about 12 mmHg compared to less than 1 mmHg with placebo.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
In vitro and animal research suggests that constituents of celery can inhibit CYP1A2. This effect has not been reported in humans.
Levothyroxine (Synthroid, Others)
Theoretically, celery seed might decrease the effects of levothyroxine.
Several cases of hypothyroidism with low T4 levels have been reported in people who were previously stabilized on levothyroxine and then started taking celery seed tablets. They presented with symptoms such as lethargy, bloating, and dry skin, and recovered when celery seed was stopped. However, celery stem and leaf has been associated with case reports of hyperthyroidism in patients with no pre-existing thyroid disorders.
Lithium
Theoretically, celery might reduce excretion and increase levels of lithium due to potential diuretic effects.
Celery is thought to have diuretic properties. However, this effect has not been confirmed in humans.
Venlafaxine (Effexor)
Theoretically, celery root extract might increase blood levels of venlafaxine.
There is one case report of a patient who experienced medication-induced bipolar disorder after beginning to take celery root extract 1000 mg daily along with venlafaxine 75 mg and St. John's wort 600 mg daily. Symptoms included confusion, speech abnormalities, manic affect, and visual hallucinations. The plasma level of venlafaxine was 476.8 ng/mL (normal range 195-400 ng/mL). It is theorized that celery root increased venlafaxine levels by inhibiting cytochrome P450 2D6.
Acetaminophen (Tylenol, Others)
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Animal research suggests that concomitant use of celery juice plus acetaminophen prolongs the effects of acetaminophen. This effect has been attributed to a decrease in hepatic cytochrome P450 activity. However, other animal research shows that pretreatment with celery root extract protects against acetaminophen-induced acute liver failure. These effects have not been reported in humans.
Photosensitizing Drugs
Theoretically, celery might increase the risk of photosensitivity reactions when taken with photosensitizing drugs.
Laboratory research shows that celery contains photosensitizing agents such as phenols and psoralens.
Gota Kola
Cns Depressants
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
In vitro research suggests that gotu kola may have sedative effects via binding of GABA receptors.
Hepatotoxic Drugs
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
There are at least four case reports of hepatotoxicity associated with the use of gotu kola. However, more information is needed to determine if gotu kola was the causative factor in these cases.
Rosemary
Anticoagulant/Antiplatelet Drugs
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research suggests that rosemary inhibits platelet aggregation.
Antidiabetes Drugs
Theoretically, taking rosemary with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that rosemary extract can decrease blood glucose levels in diabetic models. However, research in humans is conflicting. Although rosemary powder decreased blood glucose levels in healthy adults, no change in blood glucose levels was seen in adults with type 2 diabetes, most of whom were taking antidiabetes drugs.
Aspirin
Theoretically, rosemary might have additive effects with salicylate-containing drugs such as aspirin.
Rosemary is reported to contain salicylates.
Choline Magnesium Trisalicylate (Trilisate)
Theoretically, rosemary might have additive effects with salicylate-containing drugs such as choline magnesium trisalicylate.
Rosemary is reported to contain salicylate.
Salsalate (Disalcid)
Theoretically, rosemary might have additive effects with salicylate-containing drugs such as salsalate.
Rosemary is reported to contain salicylate.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that rosemary induces CYP1A2 enzymes. This effect has not been reported in humans.
European Mistletoe
Antihypertensive Drugs
Theoretically, European mistletoe might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research suggests that European mistletoe extracts have hypotensive effects.
Immunosuppressants
Theoretically, European mistletoe might decrease the effectiveness of immunosuppressants.
Clinical and in vitro studies suggest that European mistletoe might have immunostimulant effects.
Tribulus
Antidiabetes Drugs
Taking tribulus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that Tribulus can lower blood glucose levels in adults with type 2 diabetes who are taking antidiabetes medications.
Antihypertensive Drugs
Theoretically, taking tribulus with antihypertensive drugs might increase the risk of hypotension.
Animal research shows that tribulus can lower blood pressure by inhibiting angiotensin-converting enzyme (ACE). Tribulus has also demonstrated hypotensive effects in pre-hypertensive adults.
Lithium
Theoretically, tribulus might increase the levels and clinical effects of lithium.
Tribulus is thought to have diuretic properties. Due to these potential diuretic effects, tribulus might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.
Hawthorn
Nitrates
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Some evidence shows that hawthorn might lower blood pressure due to vasodilatory effects.
Phosphodiesterase-5 Inhibitors
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Hawthorn might inhibit PDE-5 and cause vasodilation.
Anticoagulant/Antiplatelet Drugs
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research shows that hawthorn can inhibit platelet aggregation. However, its effect in humans is unclear. One observational study shows that patients taking hawthorn shortly before undergoing coronary artery bypass graft (CABG) surgery or valve replacement surgery have a 10% incidence of postoperative bleeding, compared with 1% in those who never consumed hawthorn extract. However, clinical research shows that taking a specific preparation of dried hawthorn leaves and flowers (Crataesor, Soria Natural Lab) 800 mg three times daily for 15 days does not affect platelet aggregation or levels of thromboxane B2, the metabolite of thromboxane A2, in healthy humans.
Beta-Blockers
Theoretically, concomitant use might cause additive effects on blood pressure and heart rate.
Some evidence shows that hawthorn might lower blood pressure and heart rate.
Calcium Channel Blockers
Theoretically, concomitant use might cause additive coronary vasodilation and hypotensive effects.
Some evidence shows that hawthorn might lower blood pressure due to vasodilatory effects.
Digoxin (Lanoxin)
Theoretically, hawthorn might potentiate the effects and adverse effects of digoxin.
Hawthorn appears to improve cardiac output; however, hawthorn does not appear to affect digoxin pharmacokinetics. Case reports suggest that at least one species of hawthorn root extract (Crataegus mexicana) may produce adverse effects similar to digoxin and can cross-react with digoxin assays, leading to falsely elevated plasma digoxin levels.
Honeysuckle
Anticoagulant/Antiplatelet Drugs
Theoretically, honeysuckle might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that polyphenols extracted from honeysuckle can inhibit platelet aggregation.
Oat
Antidiabetes Drugs
Theoretically, oats may have additive effects with antidiabetic agents and might increase the risk of hypoglycemia.
Consuming oats can decrease blood glucose in patients with diabetes. In those who require insulin, taking oats 100 grams daily for 2 days reduces the insulin dose required to achieve metabolic control.
Insulin
Concomitant use of oats and insulin might increase the risk of hypoglycemia.
In patients with insulin-dependent type 2 diabetes, taking oats 100 grams daily for 2 days reduces the insulin dose required to achieve metabolic control.
Brand information
Manufacturer and brand details for Advanced BP, from the product label.
New Sun
See all New Sun products- Name
- New Sun, Inc.
- City
- Hendersonville
- State
- NC
- ZipCode
- 28792
- Phone Number
- (800) 544-0777
- Web Address
- mynewsun.com
Advanced BP by New Sun: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Advanced BP’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Hawthorn
Interacts with 191 drugsHawthorn is a plant traditionally used for heart-related complaints, and some studies suggest it may modestly help symptoms of mild heart failure when added to standard care. However, the ev...
Read the full Hawthorn monograph → Herb & supplement monographPassion Flower
Interacts with 836 drugsPassion flower is a traditional calming herb that many people use for anxiety and sleep. Early studies hint it may help with mild anxiety and restlessness, but the evidence is limited and mo...
Read the full Passion Flower monograph → Herb & supplement monographEuropean Mistletoe
Interacts with 293 drugsEuropean mistletoe is a parasitic plant most studied as an injectable extract used alongside conventional cancer care in some European countries, mainly to improve quality of life rather tha...
Read the full European Mistletoe monograph → Herb & supplement monographHoneysuckle
Interacts with 122 drugsHoneysuckle, especially Japanese honeysuckle flower (Lonicera japonica), is a staple of traditional Chinese medicine used mainly for colds, sore throat, and inflammation. Modern human eviden...
Read the full Honeysuckle monograph → Herb & supplement monographChrysanthemum
Chrysanthemum flowers are most often used as a soothing tea in traditional Chinese medicine and as a folk remedy for eye irritation, colds, and minor inflammation. Solid human evidence for t...
Read the full Chrysanthemum monograph → Herb & supplement monographTribulus
Interacts with 259 drugsTribulus is a plant supplement most often marketed to boost libido, testosterone, and athletic performance, but the human evidence behind these claims is weak and inconsistent. It is general...
Read the full Tribulus monograph → Herb & supplement monographCelery
Interacts with 651 drugsCelery is a common vegetable that is also taken as a seed extract or oil supplement, mainly for blood pressure, fluid retention, and joint discomfort. Human evidence for these supplement use...
Read the full Celery monograph → Herb & supplement monographGotu Kola
Interacts with 579 drugsGotu kola is a traditional Ayurvedic and Asian herb that people use for wound healing, circulation, skin problems, and as a calming or memory-supporting herb. Some early studies suggest poss...
Read the full Gotu Kola monograph → Herb & supplement monographOats
Interacts with 86 drugsOats are a well-studied whole grain whose soluble fiber (beta-glucan) can help lower cholesterol and support heart health when eaten regularly. As a food, oats are safe for most people, and...
Read the full Oats monograph → Herb & supplement monographRosemary
Interacts with 372 drugsRosemary is a fragrant Mediterranean herb that is safe and flavorful in normal food amounts. Some early research suggests possible benefits for memory, mood, and hair growth, but the evidenc...
Read the full Rosemary monograph →Sources & How We Checked
Advanced BP's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 216 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Hawthorn 25 references
- Tauchert M. Efficacy and safety of crataegus extract WS 1442 in comparison with placebo in patients with chronic stable New York Heart Association class-III heart failure. Am Heart J 2002;143:910-5. PubMed
- Pittler MH, Schmidt K, Ernst E. Hawthorn extract for treating chronic heart failure: meta-analysis of randomized trials. Am J Med 2003;114:665-74.. PubMed
- Chang Q, Zuo Z, Harrison F, Chow MS. Hawthorn. J Clin Pharmacol 2002;42:605-12.
- Holubarsch CJ, Colucci WS, Meinertz T, et al. The efficacy and safety of Crataegus extract WS 1442 in patients with heart failure: the SPICE trial. Eur J Heart Fail 2008;10:1255-63. PubMed
- Pittler MH, Guo R, and Ernst E. Hawthorn extract for treating chronic heart failure. Cochrane.Database.Syst Rev 2008:CD005312. PubMed
- Zick SM, Vautaw BM, Gillespie B, Aaronson KD. Hawthorn Extract Randomized Blinded Chronic Heart Failure (HERB CHF) trial. Eur J Heart Fail. 2009;11:990-99. PubMed
- Werner NS, Duschek S, and Schandry R. D-camphor-crataegus berry extract combination increases blood pressure and cognitive functioning in the elderly - a randomized, placebo controlled double blind study. Phytomedicine. 2009;16:1077-82. PubMed
- Dalli E, Colomer E, Tormos MC, et al. Crataegus laevigata decreases neutrophil elastase and has hypolipidemic effect: a randomized, double-blind, placebo-controlled trial. Phytomedicine. 6-15-2011;18:769-75. PubMed
- Maek-a-nantawat W, Phonrat B, Dhitavat J, et al. Safety and efficacy of CKBM-A01, a Chinese herbal medicine, among asymptomatic HIV patients. Southeast Asian J Trop.Med Public Health 2009;40:494-501.
- Asher GN, Viera AJ, Weaver MA, et al. Effect of hawthorn standardized extract on flow mediated dilation in prehypertensive and mildly hypertensive adults: a randomized, controlled cross-over trial. BMC.Complement Altern.Med 2012;12:26. PubMed
- Walker AF, Marakis G, Simpson E, et al. Hypotensive effects of hawthorn for patients with diabetes taking prescription drugs: a randomised controlled trial. Br J Gen.Pract 2006;56:437-43.
- Daniele C, Mazzanti G, Pittler MH, et al. Adverse-event profile of Crataegus spp.: a systematic review. Drug Saf 2006;29:523-35. PubMed
- Tankanow R, Tamer HR, Streetman DS, et al. Interaction study between digoxin and a preparation of hawthorn (Crataegus oxyacantha). J.Clin.Pharmacol. 2003;43:637-42. DOI
- Tauchert, M., Gildor, A., and Lipinski, J. [High-dose Crataegus extract WS 1442 in the treatment of NYHA stage II heart failure]. Herz 1999;24(6):465-474.
- Horoz, M., Gok, E., Genctoy, G., Ozcan, T., Olmaz, R., Akca, M., Kiykim, A., and Gurses, I. Crataegus orientalis associated multiorgan hypersensitivity reaction and acute renal failure. Intern.Med 2008;47(23):2039-2042. PubMed
- Dalli, E., Valles, J., Cosin-Sales, J., Santos, M. T., Moscardo, A., Milara, J., and Sotillo, J. F. Effects of hawthorn (Crataegus laevigata) on platelet aggregation in healthy volunteers. Thromb.Res 2011;128(4):398-400. PubMed
- Rogov VD. [Toxiderma due to the fruits of the hawthorn]. Vestn Dermatol Venerol 1984;7(7):46-47.
- Loew D, Albrecht M, and Podzuweit H. Efficacy and tolerability of a Hawthorn preparation in patients with heart failure Stage I and II according to NYHA - a surveillance study. Phytomedicine 1996;3(Suppl 1):92.
- Rababa'h AM, Altarabsheh SE, Haddad O, Deo SV, Obeidat Y, Al-Azzam S. Hawthorn Herb Increases the Risk of Bleeding after Cardiac Surgery: An Evidence-Based Approach. Heart Surg Forum 2016;19(4):E175-9. PubMed
- Shatoor AS, Soliman H, Al-Hashem F, Gamal BE, Othman A, El-Menshaw N. Effect of hawthorn (Crataegus aronia syn. Azarolus (L)) on platelet function in albino wistar rats. Thromb Res 2012;130(1):75-80. PubMed
- Vibes J, Lasserre B, Gleye J, Declume C. Inhibition of thromboxane A2 biosynthesis in vitro by the main components of Crataegus oxyacantha (hawthorn) flower heads. Prostaglandins Leukot Essent Fatty Acids 1994;50(4):173-5. PubMed
- Rogers KL, Grice ID, Griffiths LR. Inhibition of platelet aggregation and 5-HT release by extracts of Australian plants used traditionally as headache treatments. Eur J Pharm Sci 2000;9(4):355-63. PubMed
- Zhou CC, Huang XX, Gao PY, et al. Two new compounds from Crataegus pinnatifida and their antithrombotic activities. J Asian Nat Prod Res 2014;16(2):169-74.
- Palmer KG, Lebin JA, Cronin MT, Mazor SS, Burns RA. Crataegus mexicana (Tejocote) Exposure Associated with Cardiotoxicity and a Falsely Elevated Digoxin Level. J Med Toxicol. 2019;15(4):295-298. PubMed
- Espinosa J, Bassett R, Lucerna A, Finn D. Hawthorne root (Crataegus mexicana) toxicity. Am J Emerg Med. 2024;78:242.e5-242.e6. PubMed
Passion Flower 19 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Fisher AA, Purcell P, Le Couteur DG. Toxicity of Passiflora incarnata L. J Toxicol Clin Toxicol 2000;38:63-6.
- Akhondzadeh S, Naghavi HR, Shayeganpour A, et al. Passionflower in the treatment of generalized anxiety: a pilot double-blind randomized controlled trial with oxazepam. J Clin Pharm Ther 2001;26:363-7. PubMed
- Farnsworth N, Bingel A, Cordell G, et al. Potential value of plants as sources of new antifertility agents I. J Pharm Sci 1975;64:535-98. DOI
- Mori A, Hasegawa K, Murasaki M, et al. Clinical evaluation of Passiflamin (passiflora extract) on neurosis - multicenter double blind study in comparison with mexazolam. Rinsho Hyoka (Clinical Evaluation) 1993;21:383-440.
- Miyasaka LS, Atallah AN, Soares BG. Passiflora for anxiety disorder. Cochrane Database Syst Rev 2007;(1):CD004518. DOI
- Speroni E., Minghetti A. Neuropharmacological activity of extracts from Passiflora incarnata. Planta Med. 1988;54:488-91.
- Capasso A., Sorrentino L. Pharmacological studies on the sedative and hypnotic effect of Kava kava and Passiflora extracts combination. Phytomedicine. 2005;12:39-45. PubMed
- Carrasco MC, Vallejo JR, Pardo-de-Santayana M, et al. Interactions of Valeriana officinalis L. and Passiflora incarnata L. in a patient treated with lorazepam. Phytother Res. 2009 Dec;23:1795-6.
- Smith, G. W., Chalmers, T. M., and Nuki, G. Vasculitis associated with herbal preparation containing Passiflora extract. Br J Rheumatol. 1993;32(1):87-88.
- Soulimani, R., Younos, C., Jarmouni, S., Bousta, D., Misslin, R., and Mortier, F. Behavioural effects of Passiflora incarnata L. and its indole alkaloid and flavonoid derivatives and maltol in the mouse. J Ethnopharmacol. 1997;57(1):11-20. PubMed
- Nojoumi M, Ghaeli P, Salimi S, Sharifi A, Raisi F. Effects of Passion Flower Extract, as an Add-On Treatment to Sertraline, on Reaction Time in Patients ?with Generalized Anxiety Disorder: A Double-Blind Placebo-Controlled Study. Iran J Psychiatry. 2016;1
- Rokhtabnak F, Ghodraty MR, Kholdebarin A, et al. Comparing the Effect of Preoperative Administration of Melatonin and Passiflora incarnata on Postoperative Cognitive Disorders in Adult Patients Undergoing Elective Surgery. Anesth Pain Med. 2016;7(1):e4123 PubMed
- Dantas LP, de Oliveira-Ribeiro A, de Almeida-Souza LM, Groppo FC. Effects of passiflora incarnata and midazolam for control of anxiety in patients undergoing dental extraction. Med Oral Patol Oral Cir Bucal. 2017;22(1):e95-e101. PubMed
- Ozturk Z, Kalayci CC. Pregnancy outcomes in psychiatric patients treated with passiflora incarnata. Complement Ther Med. 2018 Feb;36:30-32. PubMed
- da Cunha RS, Amorim KS, Gercina AC, et al. Herbal medicines as anxiolytics prior to third molar surgical extraction. A randomized controlled clinical trial. Clin Oral Investig. 2020. PubMed
- Schäfer AM, Gilgen PM, Spirgi C, et al. Constituents of Passiflora incarnata, but Not of Valeriana officinalis, Interact with the Organic Anion Transporting Polypeptides (OATP)2B1 and OATP1A2. Planta Med. 2021. PubMed
- Mazzari ALDA, Lacerda MG, Milton FA, et al. In vitro effects of European and Latin-American medicinal plants in CYP3A4 gene expression, glutathione levels, and P-glycoprotein activity. Front Pharmacol 2022;13:826395. PubMed
European Mistletoe 35 references
- Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Harvey J, Colin-Jones DG. Mistletoe hepatitis. Br Med J (Clin Res Ed) 1981;282:186-7.
- Natl Cancer Inst. Mistletoe (PDQ). CancerNet. www.cancernet.nci.nih.gov/cam/mistletoe.htm#7 (Accessed 30 March 2001).
- Kaegi E. Unconventional therapies for cancer: 3. Iscador. Task Force on Alternative Therapies of the Canadian Breast Cancer Research Initiative. CMAJ 1998;158:1157-9.
- Grossarth-Matichek R, Kiene H, Baumgartner SM, Ziegler R. Use of Iscador, an extract of European mistletoe (Viscum album), in cancer treatment: prospective nonrandomized and randomized matched-pair studies nested within a cohort study. Altern Ther Health
- Huber R, Barth H, Schmitt-Graff A, Klein R. Hypereosinophilia induced by high-dose intratumoral and peritumoral mistletoe application to a patient with pancreatic carcinoma. J Altern Complement Med 2000;6:305-10. PubMed
- Timoshenko AV, Cherenkevich SN, Gabius HJ. Viscum album agglutinin-induced aggregation of blood cells and the lectin effects on neutrophil function. Biomed Pharmacother 1995;49:153-8.. PubMed
- Bussing A, Regnery A, Schweizer K. Effects of Viscum album L. on cyclophosphamide-treated peripheral blood mononuclear cells in vitro: sister chromatid exchanges and activation/proliferation marker expression. Cancer Lett 1995;94:199-205.. PubMed
- Deliorman D, Calis I, Ergun F. A new acyclic monoterpene glucoside from Viscum album ssp. album. Fitoterapia 2001;72:101-5. PubMed
- Finall AI, McIntosh SA, Thompson WD. Subcutaneous inflammation mimicking metastatic malignancy induced by injection of mistletoe extract. BMJ 2006;333:1293-4. PubMed
- Bauer C, Oppel T, Rueff F, Przybilla B. Anaphylaxis to viscotoxins of mistletoe (Viscum album) extracts. Ann Allergy Asthma Immunol 2005;94:86-9. PubMed
- Schoffski P, Breidenbach I, Krauter J, et al. Weekly 24 h infusion of aviscumine (rViscumin): A phase I study in patients with solid tumours. Eur J Cancer 2005;41:1431-8.
- Chernyshov VP, Omelchenko LI, Heusser P, and et al. Immunomodulatory actions of Viscum album (Iscador) in children with recurrent respiratory disease as a result of the Chernobyl nuclear accident. Complementary Therapies in Medicine 1997;5(3):141-146. DOI
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