Major interaction on record — check this product against your medications before combining. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Sulfurzyme Ingredients & Drug Interactions

by Young Living Essential Oils

Sulfurzyme label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Sulfurzyme against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Sulfurzyme is a dietary supplement by Young Living Essential Oils with 2 active ingredients. Its ingredients are commonly taken for general antioxidant support, eye health, immune support.Based on those ingredients, 1,000 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Ningxia Wolfberry, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Sulfurzyme by Young Living Essential Oils

Ask about any prescription or over-the-counter medication and we check it for interactions with Sulfurzyme by Young Living Essential Oils — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Sulfurzyme by Young Living Essential Oils

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Sulfurzyme Blend” is a proprietary blend — the label gives one combined amount (1.80 Gram(s)) without saying how much of each component you get.

Sulfurzyme contains two active ingredients. Ningxia Wolfberry powder is goji berry in a concentrated form.

Methylsulfonylmethane (MSM) is an organic sulfur compound. The capsule also contains inactive ingredients — hypromellose, rice flour, magnesium stearate, and silica — which are fillers and binders to hold the capsule together.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: joint health and exercise recovery support.
  • We looked for evidence on: joint inflammation, muscle recovery, exercise-induced soreness.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence for goji berry in Sulfurzyme is not established in the data we hold. Our monograph rates it as having insufficient reliable evidence to support its use for sunburn, cardiovascular disease, high blood pressure, obesity, or quality of life.

We have no effectiveness ratings on file for methylsulfonylmethane.

The evidence, ingredient by ingredient Goji

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Goji berry from food sources is generally well tolerated, but concentrated supplements like this one have less safety data than the whole fruit. A small number of people have reported allergic reactions — ranging from itching and swelling of the lips and face to anaphylaxis — after consuming goji berries.

There are also isolated case reports of liver inflammation (hepatitis) tied to goji or goji-containing products, though it's sometimes unclear if goji alone was the cause. If you're pregnant, the safety data advises against using medicinal amounts of goji due to limited data and traditional concerns about effects on the uterus.

If you're breastfeeding, there isn't enough reliable data on supplement use, so caution is advised — talk with your doctor or pharmacist about whether this is right for you.

Side effects, ingredient by ingredient Goji

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Goji.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 1,001 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Sulfurzyme, double-check if you take warfarin or other blood thinners — goji can increase bleeding risk. Also check any CYP2D6, CYP2C19, CYP2C9, or CYP3A4 substrates (your pharmacist can tell you if your drugs are in these groups), blood pressure medications, diabetes drugs, and flecainide.

Altogether, these interactions span 988 individual medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Sulfurzyme is worth considering only if you take no other medications, especially not blood thinners, heart rhythm drugs, or blood pressure medications. If you take any prescription drug, check it against the interaction tool below first.

If you're pregnant or breastfeeding, talk with your pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 20, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sulfurzyme, straight from the product label.

Brand Young Living Essential Oils
Net contents 300 Capsule(s)
Market status On market
Date entered into DSLD Jun 20, 2024
DSLD ID 315157
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sulfurzyme by Young Living Essential Oils, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
150
IngredientAmount% DV
Methylsulfonylmethane0 NP--
Ningxia Wolfberry, Powder0 NP--
Sulfurzyme Blend1.8 Gram(s)--

Other ingredients: Hypromellose, Rice Flour, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Formula

An MSM and Ningxia Wolfberry Fruit Powder Supplement

Sulfurzyme combines MSM, an organic form of dietary sulfur, with pure wolfberry powder for a supplement that supports recovery time and acute inflammation associated with exercise and overall joint health.

Seals/Symbols

Seed to Seal Young Living Est 1994 Quality Commitment

Suggested/Recommended/Usage/Directions

Directions: Take 2 capsules 2 times daily or as needed. Take 1 hour before or after meals.

Precautions

Caution: Keep out of reach of children.

If you are pregnant, nursing, taking medication, or have a medical condition, consult a health care professional prior to use.

Storage

Storage: Keep in a cool, dark place.

General Statements

Formulated by D. Gary Young

This package may not be recycled in your area

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Sulfurzyme by Young Living Essential Oils label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Sulfurzyme label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Sulfurzyme by Young Living Essential Oils

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container150 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sulfurzyme Blend

1.8 Gram(s) per serving

Other (inactive) ingredients: Hypromellose, Rice Flour, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Sulfurzyme by Young Living Essential Oils Drug Interactions

Want to check YOUR meds against Sulfurzyme?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,000Drugs
2 Major 930 Moderate 68 Minor

Ingredients driving the most interactions

Ningxia Wolfberry, Powder 1,000

Individual Drug Interactions

The ingredients in Sulfurzyme interact with 1,000 drugs. Click any drug to see the details.

1 of the 2 ingredients in Sulfurzyme interact with drugs. Each result below shows which ingredient is responsible. Ningxia Wolfberry, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Sulfurzyme with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Ningxia Wolfberry, Powder8 drug types · 1,000 drugs

Warfarin (Coumadin)

Goji can increase the effects of warfarin and possibly increase the risk of bleeding.
There are at least 5 case reports of increased international normalized ratio (INR) in patients stabilized on warfarin who began drinking goji juice, concentrated goji tea, or goji wine. Goji may inhibit the metabolism of warfarin by cytochrome P450 2C9 (CYP2C9).

Likelihood Probable Evidence D
Antihypertensive Drugs

Theoretically, concomitant use of goji root bark, but not goji fruit, with antihypertensive drugs might have additive effects.
Animal and in vitro research suggest that goji root bark has hypotensive effects. However, goji fruit juice does not appear to reduce systolic or diastolic blood pressure in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, goji berry might inhibit CYP2C19 and reduce metabolism of CYP2C19 substrates.
In vitro research shows that goji berry tincture and juice inhibit CYP2C19 enzymes. Concomitant use with goji may decrease metabolism and increase levels of CYP2C19 substrates. However, this has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, goji berry might inhibit CYP2C9 and reduce metabolism of CYP2C9 substrates.
In vitro research shows that goji berry tincture and juice inhibit CYP2C9 enzymes. Additionally, multiple case reports suggest that goji berry concentrated tea and juice inhibit the metabolism of warfarin, a CYP2C9 substrate. Concomitant use with goji may decrease metabolism and increase levels of CYP2C9 substrates.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, goji berry might inhibit CYP2D6 and reduce metabolism of CYP2D6 substrates.
In vitro research shows that goji berry juice inhibits CYP2D6 enzymes. Concomitant use with goji may decrease metabolism and increase levels of CYP2D6 substrates. However, this has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, goji berry might inhibit CYP3A4 and reduce metabolism of CYP3A4 substrates.
In vitro research shows that goji berry juice inhibits CYP3A4 enzymes. Concomitant use with goji may decrease metabolism and increase levels of CYP3A4 substrates. However, this has not been reported in humans.

Likelihood Possible Evidence D
Flecainide (Tambocor)

Theoretically, goji berry might increase the levels and clinical effects of flecainide.
In one case report, a 75-year-old patient stable on flecainide and warfarin presented to the emergency room with fainting and pleomorphic arrhythmia caused by flecainide toxicity. Flecainide toxicity was attributed to drinking 1-2 glasses of concentrated goji tea daily for 2 weeks. Theoretically, goji may have inhibited the cytochrome P450 2D6 (CYP2D6) metabolism of flecainide.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, concomitant use of goji fruit polysaccharides or goji root bark with antidiabetes drugs might have additive effects.
Animal and in vitro research show that goji root bark and fruit polysaccharides might have hypoglycemic effects. However, clinical research has only shown that taking goji fruit polysaccharides with or without antidiabetes drugs modestly reduces postprandial glucose when compared with control, with no reports of hypoglycemia.

Likelihood Possible Evidence B
Ningxia Wolfberry, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Sulfurzyme, from the product label.

Young Living Essential Oils

See all Young Living Essential Oils products
Name
Young Living Essential Oils, LC
City
Lehi
State
UT
ZipCode
84043
Phone Number
1-800-371-3515
Web Address
YoungLiving.com
Pharmacist Counseling Corner

Sulfurzyme by Young Living Essential Oils: Common Questions

Does Sulfurzyme by Young Living Essential Oils interact with any medications?
Yes. Based on its ingredients, Sulfurzyme has a known interaction with 1,000 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Sulfurzyme contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Sulfurzyme if I'm on warfarin?
No — goji berry in this product can increase how much warfarin stays in your body and raise the risk of bleeding. Case reports show people stable on warfarin developed blood-thinning problems after consuming goji juice and tea. Talk with your doctor about whether you should take this.
What's MSM, and why is it in here?
MSM stands for methylsulfonylmethane — it's an organic sulfur compound. We don't have interaction data or effectiveness data on file for it, so I can't tell you what role it plays in this product or how it might affect your medications.
Are there any side effects I should know about?
Most people tolerate goji berry well when eaten as food. However, allergic reactions have been reported — symptoms can range from itching and mouth tingling to facial swelling and, rarely, anaphylaxis. There are also rare case reports of liver inflammation tied to goji or goji-containing products.
Can I take this while pregnant?
No — the safety data advises against using medicinal amounts of goji during pregnancy due to limited safety data and traditional concerns about effects on the uterus. Talk with your doctor or pharmacist about your options.
Is it safe while breastfeeding?
There isn't enough reliable data on supplement use while breastfeeding, so caution is advised. Talk with your pharmacist about whether this product is appropriate for you during this time.
Does Sulfurzyme actually work?
Our data shows insufficient evidence to support its use for the conditions it's sometimes promoted for — sunburn, heart health, high blood pressure, weight, or quality of life. The evidence just isn't there yet.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Sulfurzyme is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sulfurzyme label
Go deeper

The Full Monographs Behind Sulfurzyme’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Goji

Interacts with 1,000 drugs

Goji berries are a nutritious fruit rich in antioxidants, vitamins, and plant polysaccharides, and they are safe for most people as a food. While they are popular for eye health, immune supp...

Read the full Goji monograph →
Sources

Sources & How We Checked

Sulfurzyme's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Goji 14 references
  1. Huang KC. The Pharmacology of Chinese Herbs. 2nd ed. Boca Raton, FL: CRC Press, LLC 1999.
  2. Lam AY, Elmer GW, Mohutsky MA. Possible interaction between warfarin and Lycium Barbarum. Ann Pharmacother 2001;35:1199-201.
  3. Leung H, Hung A, Hui AC, Chan TY. Warfarin overdose due to the possible effects of Lycium barbarum L. Food Chem Toxicol 2008;46:1860-2. PubMed
  4. Amagase H, Nance DM. A randomized, double-blind, placebo-controlled, clinical study of the general effects of a standardized Lycium barbarum (goji) juice, GoChi. J Altern Complement Med 2008;14:403-12.
  5. Rivera, C. A., Ferro, C. L., Bursua, A. J., and Gerber, B. S. Probable interaction between Lycium barbarum (goji) and warfarin. Pharmacotherapy 2012;32(3):e50-e53.
  6. Monzon, Ballarin S., Lopez-Matas, M. A., Saenz, Abad D., Perez-Cinto, N., and Carnes, J. Anaphylaxis associated with the ingestion of Goji berries (Lycium barbarum). J.Investig.Allergol.Clin.Immunol. 2011;21(7):567-570.
  7. Franco, M., Monmany, J., Domingo, P., and Turbau, M. [Autoimmune hepatitis triggered by consumption of Goji berries]. Med.Clin.(Barc.) 9-22-2012;139(7):320-321.
  8. Jiménez-Encarnación E, Ríos G, Muñoz-Mirabal A, Vilá LM. Euforia-induced acute hepatitis in a patient with scleroderma. BMJ Case Rep 2012;2012. PubMed
  9. Larramendi CH, García-Abujeta JL, Vicario S, García-Endrino A, López-Matas MA, García-Sedeño MD, et al. Goji berries (Lycium barbarum): Risk of allergic reactions in individuals with food allergy. J Investig Allergol Clin Immunol. 2012;22(5):345-50.
  10. Cai H, Liu F, Zuo P, Huang G, Song Z, Wang T, et al. Practical application of antidiabetic efficacy of Lycium barbarum polysaccharide in patients with type 2 diabetes. Med Chem. 2015;11(4):383-90.
  11. Potterat O. Goji (Lycium barbarum and L. chinense): Phytochemistry, pharmacology and safety in the perspective of traditional uses and recent popularity. Planta Med 2010;76(1):7-19.
  12. Guzmán CE, Guzmán-Moreno CG, Assad-Morell JL, Edgar Francisco Carrizales-Sepúlveda EF. Flecainide toxicity associated with the use of goji berries: a case report. Eur Heart J Case Rep. 2021;5(6):ytab204. PubMed
  13. Liu R, Tam TW, Mao J, et al. In vitro activity of Lycium barbarum (Goji) against major human phase I metabolism enzymes. Complement Integr Med. 2016;13(3):257-265.
  14. Zhang J, Tian L, Xie B. Bleeding due to a probable interaction between warfarin and Gouqizi (Lycium Barbarum L.). Toxicol Rep. 2015;2:1209-1212. PubMed

See these in context on the Goji monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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