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Dietary supplement

Super Joints 1500 mg Ingredients & Drug Interactions

by 8WeeksOut

Super Joints 1500 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Super Joints 1500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Super Joints 1500 mg is a dietary supplement by 8WeeksOut with 1 active ingredient. Its ingredients are commonly taken for bone fracture healing, joint pain and bone health, weight management.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cissus quadrangularis (stem) extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Super Joints 1500 mg by 8WeeksOut

Ask about any prescription or over-the-counter medication and we check it for interactions with Super Joints 1500 mg by 8WeeksOut — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Super Joints 1500 mg by 8WeeksOut

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 17, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Cissus quadrangularis stem extract at 1,500 mg per capsule. Cissus is a plant extract traditionally used in herbal medicine and studied for its effects on body weight and metabolic markers.

The capsules also contain gelatin, rice flour, and magnesium stearate as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Cissus Quadrangularis's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: joint pain relief and bone fracture healing.
  • We looked for evidence on: Fractures, Joint pain, Osteoporosis, Osteopenia, Rheumatoid arthritis (RA), Gout — and 3 related terms.
  • The closest evidence on file: Cissus Quadrangularis is rated "Insufficient Reliable Evidence To Rate" for Osteopenia (Natural Medicines).
  • Also on file: Cissus Quadrangularis is rated "Insufficient Reliable Evidence To Rate" for Fractures, Osteoporosis, Joint pain, Rheumatoid arthritis (RA), and more.

Cissus quadrangularis has possibly effective evidence for obesity (meaning there's some evidence, but it's not yet definitive). For other uses in this product — high cholesterol (hyperlipidemia), weak bones (osteopenia), cancer, and epilepsy — the evidence is too thin to rate.

If you're considering it mainly for joint or bone support, understand that the data we hold doesn't establish effectiveness for those purposes.

The evidence, ingredient by ingredient Cissus Quadrangularis

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Cissus quadrangularis is generally well tolerated in short-term use, though long-term safety hasn't been thoroughly studied. Reported side effects in trials — headache, insomnia, flatulence, diarrhea, gastritis, and dry mouth — occurred at rates similar to or lower than placebo, so they're not common.

The safety data advises against use during pregnancy and breastfeeding because there isn't enough research. If you're pregnant, nursing, or planning to become pregnant, talk with your doctor or pharmacist about whether this product is right for you.

Side effects, ingredient by ingredient Cissus Quadrangularis

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Cissus Quadrangularis.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any antidiabetes drugs — insulin, metformin, sulfonylureas, GLP-1 agonists, or any other blood-sugar medication — check with your doctor or pharmacist before starting this product. Cissus quadrangularis may increase the risk of low blood sugar when combined with these medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This single-ingredient product may be worth considering if you're interested in weight management and have discussed it with your healthcare provider. However, if you take any blood-sugar-lowering medication, you need to check with your doctor or pharmacist first — Cissus may strengthen that drug's effect and lower your blood sugar too far.

Long-term safety data is limited, so it's best used short-term and under guidance.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Super Joints 1500 mg, straight from the product label.

Brand 8WeeksOut
Barcode (UPC) 647732625622
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Jun 24, 2020
DSLD ID 228472
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Super Joints 1500 mg by 8WeeksOut, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
90
UPC/BARCODE
647732625622
IngredientAmount% DV
Cissus quadrangularis (stem) extract1500 mg--

Other ingredients: Gelatin Caps, Rice Flour, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

SuperJoints: Contains the famous award winning cissus quadragularis extract which has been the subject of several university pilot studies known for its miraculous ability to turn around stubborn joint problems.

Super Joints 1500 mg per dose

100% cissus quadrangularis

Formulation

Clinical studies have shown promise of: Analgestic joint pain relief Muscle relaxing anti-inflamatory properties Increase bone fracture healing rates Antioxidant properties Promotes improved body composition

Professional joint relief

Best of the best joint support

Suggested/Recommended/Usage/Directions

Directions: Take two capsules 30 minutes before breakfast, and two capsule 30 minutes before dinner. Once relief is achieved, take a single maintenance dose daily.

Precautions

Warnings: Keep out of reach of children.

Do not use if pregnant or breastfeeding.

Cissus quadrangularis might lower blood sugar.

Taking cissus quadrangularis along with medications for diabetes might lower blood sugar too much.

Watch for signs of low blood sugar (hypoglycemia) and monitor your blood sugar levels closely if you have diabetes and use cissus quadrangularis.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

100% money back guarantee

Award winning studies

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

ASI Food Safety FDA Registered Facility GMP Good Manufacturing Practice Consistent Quality Made in U.S.A.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Super Joints 1500 mg by 8WeeksOut label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Super Joints 1500 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Super Joints 1500 mg by 8WeeksOut

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Cissus quadrangularis (stem) extract

Interacts with
86 drugs
1500 mg per serving

Cissus quadrangularis is a traditional vine used mainly for bone health, joint pain, and weight management. Most of the supporting evidence comes from...

Cissus quadrangularis (stem) extract monograph & interactions

Other (inactive) ingredients: Gelatin Caps, Rice Flour, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Super Joints 1500 mg by 8WeeksOut Drug Interactions

Want to check YOUR meds against Super Joints 1500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Cissus quadrangularis (stem) extract 86

Individual Drug Interactions

The ingredients in Super Joints 1500 mg interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Super Joints 1500 mg interact with drugs. Each result below shows which ingredient is responsible. Cissus quadrangularis (stem) extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Super Joints 1500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Cissus quadrangularis (stem) extract1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, Cissus quadrangularis might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Small clinical studies suggest that Cissus quadrangularis might reduce fasting blood glucose in individuals with overweight or obesity.

Likelihood Possible Evidence D
Cissus quadrangularis (stem) extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Super Joints 1500 mg, from the product label.

8WeeksOut

See all 8WeeksOut products
Name
8WeeksOut
City
San Antonio
State
TX
ZipCode
78259
Web Address
www.8weeksoutlabs.com
Pharmacist Counseling Corner

Super Joints 1500 mg by 8WeeksOut: Common Questions

Does Super Joints 1500 mg by 8WeeksOut interact with any medications?
Yes. Based on its ingredients, Super Joints 1500 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Super Joints 1500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my joints?
The evidence we hold shows possibly effective data for obesity, but we don't have established effectiveness data for joint or bone support specifically. If that's your main goal, talk with your pharmacist about whether the available evidence fits your needs.
Can I take this while pregnant or breastfeeding?
No. There isn't enough safety data, so it's best avoided during pregnancy and while breastfeeding. If you're in either situation and interested in this product, discuss options with your doctor or pharmacist.
What side effects might I notice?
Headache, insomnia, flatulence, diarrhea, gastritis, and dry mouth have been reported in trials, but at rates similar to placebo — so they're uncommon. Most people tolerate it well in short-term use.
How long is it safe to take this?
Short-term use is well tolerated based on available studies, but long-term safety hasn't been thoroughly studied. Check with your pharmacist or doctor about how long you should use it.
What is Cissus quadrangularis?
It's a plant extract, sometimes called Veld Grape, studied for effects on body weight and metabolic health. This product contains the stem extract at 1,500 mg per capsule.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Super Joints 1500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Super Joints 1500 mg label
Go deeper

The Full Monographs Behind Super Joints 1500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Cissus Quadrangularis

Interacts with 86 drugs

Cissus quadrangularis is a traditional vine used mainly for bone health, joint pain, and weight management. Most of the supporting evidence comes from animal studies and a small number of hu...

Read the full Cissus Quadrangularis monograph →
Sources

Sources & How We Checked

Super Joints 1500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cissus Quadrangularis 5 references
  1. Oben J, Kuate D, Agbor G, et al. The use of a Cissus quadrangularis formulation in the management of weight loss and metabolic syndrome. Lipids Health Dis 2006, 5:24.
  2. Oben JE, Ngondi JL, Momo CN, et al. The use of Cissus quadrangularis/Irvingia gabonensis combination in the management of weight loss: a double-blind placebo-controlled study. Lipids Health Dis 2008;7:12.
  3. Panpimanmas, S., Sithipongsri, S., Sukdanon, C., and Manmee, C. Experimental comparative study of the efficacy and side effects of Cissus quadrangularis L. (Vitaceae) to Daflon (Servier) and placebo in the treatment of acute hemorrhoids. J Med Assoc.Thai
  4. Nash R, Azantsa B, Kuate D, Singh H, Oben J. The use of a stem and leaf aqueous extract of Cissus quadrangularis (CQR-300) to reduce body fat and other components of metabolic syndrome in overweight participants. J Altern Complement Med. 2019;25(1):98-106
  5. Benjawan S, Nimitphong H, Tragulpiankit P, Musigavong O, Prathanturarug S, Pathomwichaiwat T. The effect of Cissus quadrangularis L. on delaying bone loss in postmenopausal women with osteopenia: A randomized placebo-controlled trial. Phytomedicine 2022;1 PubMed

See these in context on the Cissus Quadrangularis monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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